BACKGROUND There are relatively few studies on continuing care of coronary heart disease(CHD),and its research value needs to be further clarified.AIM To investigate the effect of continuous nursing on treatment compl...BACKGROUND There are relatively few studies on continuing care of coronary heart disease(CHD),and its research value needs to be further clarified.AIM To investigate the effect of continuous nursing on treatment compliance and side effect management in patients with CHD.METHODS This is a retrospective study with patients from January 2021 to 2023.The study was divided into two groups with 30 participants in each group.Self-rating anxiety scale(SAS)and Self-rating depression scale(SDS)were used to assess patients'anxiety and depression,and medical coping questionnaire was used to assess patients'coping styles.The pelvic floor dysfunction questionnaire(PFDI-20)was used to assess the status of pelvic floor function,including bladder symptoms,intestinal symptoms,and pelvic symptoms.RESULTS SAS score decreased from 57.33±3.01before treatment to 41.33±3.42 after treatment,SDS score decreased from 50.40±1.45 to 39.47±1.57.The decrease of these two indexes was statistically significant(P<0.05).PFDI-20 scores decreased from the mean 16.83±1.72 before treatment to 10.47±1.3the mean after treatment,which was statistically significant(P<0.05).CONCLUSION The results of this study indicate that pioneering research in continuous care of CHD has a positive impact on improving patients'treatment compliance,reducing anxiety and depression levels,and improving coping styles and pelvic floor functional status.展开更多
Infantile malignant osteopetrosis （IMO） is a rare congenital disease that is characterized by an impaired function or differentiation of osteoclasts.IMO is the most severe type of osteopetrosis.Patients usually pres...Infantile malignant osteopetrosis （IMO） is a rare congenital disease that is characterized by an impaired function or differentiation of osteoclasts.IMO is the most severe type of osteopetrosis.Patients usually present various fatal manifestations soon after birth and die in infancy or childhood.Clinical features include bone marrow failure resulting in pancytopenia,hepatosplenomegaly,blindness secondary to optic nerve compression,hydrocephalus,and other neurological complications. T-cell immune regulator 1 （TCIRG1,Gene ID：10312） is one of the main genes that are responsible for the majority of IMO cases.Mutations in TCIRG1 associated with general clinical features have been reported in some studies. In this study,we reported the ocular manifestations and genetic findings of an IMO patient.展开更多
文摘BACKGROUND There are relatively few studies on continuing care of coronary heart disease(CHD),and its research value needs to be further clarified.AIM To investigate the effect of continuous nursing on treatment compliance and side effect management in patients with CHD.METHODS This is a retrospective study with patients from January 2021 to 2023.The study was divided into two groups with 30 participants in each group.Self-rating anxiety scale(SAS)and Self-rating depression scale(SDS)were used to assess patients'anxiety and depression,and medical coping questionnaire was used to assess patients'coping styles.The pelvic floor dysfunction questionnaire(PFDI-20)was used to assess the status of pelvic floor function,including bladder symptoms,intestinal symptoms,and pelvic symptoms.RESULTS SAS score decreased from 57.33±3.01before treatment to 41.33±3.42 after treatment,SDS score decreased from 50.40±1.45 to 39.47±1.57.The decrease of these two indexes was statistically significant(P<0.05).PFDI-20 scores decreased from the mean 16.83±1.72 before treatment to 10.47±1.3the mean after treatment,which was statistically significant(P<0.05).CONCLUSION The results of this study indicate that pioneering research in continuous care of CHD has a positive impact on improving patients'treatment compliance,reducing anxiety and depression levels,and improving coping styles and pelvic floor functional status.
基金This study was supported by the grants from the National Natural Science Foundation of China （No. 81570891） the National Natural Science Foundation of China （No. 81272981 ）+4 种基金 the Beijing Municipal Administration of Hospitals＇ Ascent Plan （No. DFL20150201 ） the Science and Technology Project of Beijing Municipal Science and Technology Commission （No. ZI51100001615052） the Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support （No. ZYLX201307） the Beijing Natural Science Foundation （No. 7151003） and the Advanced Health Care Professionals Development Project of Beijing Municipal Health Bureau （No. 2014-2-003）.
文摘Infantile malignant osteopetrosis （IMO） is a rare congenital disease that is characterized by an impaired function or differentiation of osteoclasts.IMO is the most severe type of osteopetrosis.Patients usually present various fatal manifestations soon after birth and die in infancy or childhood.Clinical features include bone marrow failure resulting in pancytopenia,hepatosplenomegaly,blindness secondary to optic nerve compression,hydrocephalus,and other neurological complications. T-cell immune regulator 1 （TCIRG1,Gene ID：10312） is one of the main genes that are responsible for the majority of IMO cases.Mutations in TCIRG1 associated with general clinical features have been reported in some studies. In this study,we reported the ocular manifestations and genetic findings of an IMO patient.
