BACKGROUND The liver hemodynamic changes caused by portal hypertension(PH)are closely related to various complications such as gastroesophageal varices and portosystemic shunts,which may lead to adverse clinical outco...BACKGROUND The liver hemodynamic changes caused by portal hypertension(PH)are closely related to various complications such as gastroesophageal varices and portosystemic shunts,which may lead to adverse clinical outcomes in these patients,so it is of great clinical significance to find treatment strategies with favorable clinical efficacy and low risk of complications.AIM To study the clinical efficacy of total laparoscopic splenectomy(TLS)for PH and its influence on hepatic hemodynamics and liver function.METHODS Among the 199 PH patients selected from October 2016 to October 2020,100 patients[observation group(OG)]were treated with TLS,while the remaining 99[reference group(RG)]were treated with open splenectomy(OS).We observed and compared the clinical efficacy,operation indexes[operative time(OT)and intraoperative bleeding volume],safety(intraperitoneal hemorrhage,ascitic fluid infection,eating disorders,liver insufficiency,and perioperative death),hepatic hemodynamics(diameter,velocity,and flow volume of the portal vein system),and liver function[serum alanine aminotransferase(ALT),serum aspartate aminotransferase(AST),and serum total bilirubin(TBil)]of the two groups.RESULTS The OT was significantly longer and intraoperative bleeding volume was significantly lesser in the OG than in the RG.Additionally,the overall response rate,postoperative complications rate,and liver function indexes(ALT,AST,and TBil)did not differ significantly between the OG and RG.The hepatic hemodynamics statistics showed that the pre-and postoperative blood vessel diameters in the two cohorts did not differ statistically.Although the postoperative blood velocity and flow volume reduced significantly when compared with the preoperative values,there were no significant inter-group differences.CONCLUSION TLS contributes to comparable clinical efficacy,safety,hepatic hemodynamics,and liver function as those of OS in treating PH,with a longer OT but lesser intraoperative blood loss.展开更多
We investigate the quantum entanglement in a non-Hermitian kicking system.In the Hermitian case,the out-of-time ordered correlators(OTOCs)exhibit the unbounded power-law increase with time.Correspondingly,the linear e...We investigate the quantum entanglement in a non-Hermitian kicking system.In the Hermitian case,the out-of-time ordered correlators(OTOCs)exhibit the unbounded power-law increase with time.Correspondingly,the linear entropy,which is a common measurement of entanglement,rapidly increases from zero to almost unity,indicating the formation of quantum entanglement.For strong enough non-Hermitian driving,both the OTOCs and linear entropy rapidly saturate as time evolves.Interestingly,with the increase of non-Hermitian kicking strength,the long-time averaged value of both OTOCs and linear entropy has the same transition point where they exhibit the sharp decrease from a plateau,demonstrating the disentanglment.We reveal the mechanism of disentanglement with the extension of Floquet theory to non-Hermitian systems.展开更多
We investigate both the quantum and classical dynamics of a non-Hermitian system via a kicked rotor model with PT symmetry.For the quantum dynamics,both the mean momentum and mean square of momentum exhibit the stairc...We investigate both the quantum and classical dynamics of a non-Hermitian system via a kicked rotor model with PT symmetry.For the quantum dynamics,both the mean momentum and mean square of momentum exhibit the staircase growth with time when the system parameter is in the neighborhood of the PT symmetry breaking point.If the system parameter is much larger than the PT symmetry breaking point,the accelerator mode results in the directed spreading of the wavepackets as well as the ballistic diffusion in momentum space.For the classical dynamics,the non-Hermitian kicking potential leads to the exponentially-fast increase of classical complex trajectories.As a consequence,the imaginary part of the trajectories exponentially diffuses with time,while the real part exhibits the normal diffusion.Our analytical prediction of the exponential diffusion of imaginary momentum and its breakdown time is in good agreement with numerical results.The quantum signature of the chaotic diffusion of the complex trajectories is reflected by the dynamics of the out-of-timeorder correlators(OTOC).In the semiclassical regime,the rate of the exponential increase of the OTOC is equal to that of the exponential diffusion of the complex trajectories.展开更多
We investigate the quantum to classical transition induced by two-particle interaction via a system of periodically kicked particles.The classical dynamics of particle 1 is almost unaffected in condition that its mass...We investigate the quantum to classical transition induced by two-particle interaction via a system of periodically kicked particles.The classical dynamics of particle 1 is almost unaffected in condition that its mass is much larger than that of particle 2.Interestingly,such classically weak influence leads to the quantum to classical transition of the dynamical behavior of particle 1.Namely,the quantum diffusion of this particle undergoes the transition from dynamical localization to the classically chaotic diffusion with the decrease of the effective Planck constantħeff.The behind physics is due to the growth of entanglement in the system.The classically very weak interaction leads to the exponential decay of purity in condition that the classical dynamics of external degrees freedom is strongly chaotic.展开更多
基金The study was reviewed and approved by the Chinese PLA General Hospital Institutional Review Board(Approval No.2010068D).
文摘BACKGROUND The liver hemodynamic changes caused by portal hypertension(PH)are closely related to various complications such as gastroesophageal varices and portosystemic shunts,which may lead to adverse clinical outcomes in these patients,so it is of great clinical significance to find treatment strategies with favorable clinical efficacy and low risk of complications.AIM To study the clinical efficacy of total laparoscopic splenectomy(TLS)for PH and its influence on hepatic hemodynamics and liver function.METHODS Among the 199 PH patients selected from October 2016 to October 2020,100 patients[observation group(OG)]were treated with TLS,while the remaining 99[reference group(RG)]were treated with open splenectomy(OS).We observed and compared the clinical efficacy,operation indexes[operative time(OT)and intraoperative bleeding volume],safety(intraperitoneal hemorrhage,ascitic fluid infection,eating disorders,liver insufficiency,and perioperative death),hepatic hemodynamics(diameter,velocity,and flow volume of the portal vein system),and liver function[serum alanine aminotransferase(ALT),serum aspartate aminotransferase(AST),and serum total bilirubin(TBil)]of the two groups.RESULTS The OT was significantly longer and intraoperative bleeding volume was significantly lesser in the OG than in the RG.Additionally,the overall response rate,postoperative complications rate,and liver function indexes(ALT,AST,and TBil)did not differ significantly between the OG and RG.The hepatic hemodynamics statistics showed that the pre-and postoperative blood vessel diameters in the two cohorts did not differ statistically.Although the postoperative blood velocity and flow volume reduced significantly when compared with the preoperative values,there were no significant inter-group differences.CONCLUSION TLS contributes to comparable clinical efficacy,safety,hepatic hemodynamics,and liver function as those of OS in treating PH,with a longer OT but lesser intraoperative blood loss.
基金supported by the National Natural Science Foundation of China (Grant No. 12065009)supported by the National Natural Science Foundation of China (Grant Nos. 11704132, 11874017, and U1830111)+2 种基金Science and Technology Planning Project of Ganzhou City (Grant No. 202101095077)the Natural Science Foundation of Guangdong Province, China (Grant No. 2021A1515012350)the KPST of Guangzhou (Grant No. 201804020055)
文摘We investigate the quantum entanglement in a non-Hermitian kicking system.In the Hermitian case,the out-of-time ordered correlators(OTOCs)exhibit the unbounded power-law increase with time.Correspondingly,the linear entropy,which is a common measurement of entanglement,rapidly increases from zero to almost unity,indicating the formation of quantum entanglement.For strong enough non-Hermitian driving,both the OTOCs and linear entropy rapidly saturate as time evolves.Interestingly,with the increase of non-Hermitian kicking strength,the long-time averaged value of both OTOCs and linear entropy has the same transition point where they exhibit the sharp decrease from a plateau,demonstrating the disentanglment.We reveal the mechanism of disentanglement with the extension of Floquet theory to non-Hermitian systems.
基金Project partially supported by the National Natural Science Foundation of China(Grant Nos.12065009,11804130,and 11805165)Zhejiang Provincial Nature Science Foundation,China(Grant No.LY20A050001)。
文摘We investigate both the quantum and classical dynamics of a non-Hermitian system via a kicked rotor model with PT symmetry.For the quantum dynamics,both the mean momentum and mean square of momentum exhibit the staircase growth with time when the system parameter is in the neighborhood of the PT symmetry breaking point.If the system parameter is much larger than the PT symmetry breaking point,the accelerator mode results in the directed spreading of the wavepackets as well as the ballistic diffusion in momentum space.For the classical dynamics,the non-Hermitian kicking potential leads to the exponentially-fast increase of classical complex trajectories.As a consequence,the imaginary part of the trajectories exponentially diffuses with time,while the real part exhibits the normal diffusion.Our analytical prediction of the exponential diffusion of imaginary momentum and its breakdown time is in good agreement with numerical results.The quantum signature of the chaotic diffusion of the complex trajectories is reflected by the dynamics of the out-of-timeorder correlators(OTOC).In the semiclassical regime,the rate of the exponential increase of the OTOC is equal to that of the exponential diffusion of the complex trajectories.
基金the National Natural Science Foundation of China(Grant Nos.11864014 and 11804130).
文摘We investigate the quantum to classical transition induced by two-particle interaction via a system of periodically kicked particles.The classical dynamics of particle 1 is almost unaffected in condition that its mass is much larger than that of particle 2.Interestingly,such classically weak influence leads to the quantum to classical transition of the dynamical behavior of particle 1.Namely,the quantum diffusion of this particle undergoes the transition from dynamical localization to the classically chaotic diffusion with the decrease of the effective Planck constantħeff.The behind physics is due to the growth of entanglement in the system.The classically very weak interaction leads to the exponential decay of purity in condition that the classical dynamics of external degrees freedom is strongly chaotic.
