Cross-media analysis and reasoning is an active research area in computer science, and a promising direction for artificial intelligence. However, to the best of our knowledge, no existing work has summarized the stat...Cross-media analysis and reasoning is an active research area in computer science, and a promising direction for artificial intelligence. However, to the best of our knowledge, no existing work has summarized the state-of-the-art methods for cross-media analysis and reasoning or presented advances, challenges, and future directions for the field. To address these issues, we provide an overview as follows： （1） theory and model for cross-media uniform representation; （2） cross-media correlation understanding and deep mining; （3） cross-media knowledge graph construction and learning methodologies; （4） cross-media knowledge evolution and reasoning; （5） cross-media description and generation; （6） cross-media intelligent engines; and （7） cross-media intelligent applications. By presenting approaches, advances, and future directions in cross-media analysis and reasoning, our goal is not only to draw more attention to the state-of-the-art advances in the field, but also to provide technical insights by discussing the challenges and research directions in these areas.展开更多
Background:The association between free triiodothyronine(FT3)and long-term prognosis in dilated cardiomyopathy(DCM)patients has not been evaluated.The purpose of this study was to determine whether the level of FT3 co...Background:The association between free triiodothyronine(FT3)and long-term prognosis in dilated cardiomyopathy(DCM)patients has not been evaluated.The purpose of this study was to determine whether the level of FT3 could provide prognostic value in patients with DCM.Methods:Data of consecutive patients diagnosed with DCM were collected from October 2009 to December 2014.FT3 was measured by fluoroimmunoassay.Other biochemical markers,such as free thyroxin(FT4),thyroid-stimulating hormone,red blood cell,hemoglobin,blood urea nitrogen,and serum creatinine,were tested at the same time.Follow-up was performed every 3 months.The primary endpoint was all-cause mortality.Pearson analysis was used to evaluate the correlation of FT3 and other lab metrics with DCM patients’prognosis.The association of long-term mortality in DCM and FT3 was compared using Cox hazards model.Results:Data of 176 patients diagnosed with DCM were collected.Of them,24 patients missed FT3 values and six patients were lost to follow-up.Altogether,data of 146 patients were analyzed.During the median follow-up time of 79.9(53.5-159.6)months,nine patients lost,61 patients died(non-survival group),and 85 patients survived(survival group).FT3 was significantly lower in non-survival group than that in survival group(3.65±0.83 pmol/L vs.4.36±1.91 pmol/L;P=0.003).FT3 also showed a significantly positive correlation with red blood cell and hemoglobin,negatively correlated with age,blood urea nitrogen and serum creatinine(P<0.05),respectively.Patients in the group of lower FT3 levels(FT3≤3.49 pmol/L)suffered from a higher risk of all-cause mortality(P for log-rank=0.001).In multivariate Cox regression analysis,FT3 level was significantly associated with all-cause mortality(hazard ratio:0.70,95%confidence interval 0.52-0.95,P for trend=0.021).Conclusion:Low levels of FT3 were associated with increased all-cause mortality in patients with DCM.展开更多
基金supported by the National Natural Science Foundation of China(Nos.61371128,U1611461,61425025,and 61532005)
文摘Cross-media analysis and reasoning is an active research area in computer science, and a promising direction for artificial intelligence. However, to the best of our knowledge, no existing work has summarized the state-of-the-art methods for cross-media analysis and reasoning or presented advances, challenges, and future directions for the field. To address these issues, we provide an overview as follows： （1） theory and model for cross-media uniform representation; （2） cross-media correlation understanding and deep mining; （3） cross-media knowledge graph construction and learning methodologies; （4） cross-media knowledge evolution and reasoning; （5） cross-media description and generation; （6） cross-media intelligent engines; and （7） cross-media intelligent applications. By presenting approaches, advances, and future directions in cross-media analysis and reasoning, our goal is not only to draw more attention to the state-of-the-art advances in the field, but also to provide technical insights by discussing the challenges and research directions in these areas.
基金funded by grants from the National Key Research and Development Program of China(No.2016YFE0117000)the National Natural Science Foundation of China(Nos.81901410,81871113)+2 种基金Qinghai Provincial Natural Science Fund(No.2017-ZJ-769)333 project of Jiangsu Province(No.BRA2017544)Changzhou Science and Technology Bureau(No.CJ20190102)。
文摘Background:The association between free triiodothyronine(FT3)and long-term prognosis in dilated cardiomyopathy(DCM)patients has not been evaluated.The purpose of this study was to determine whether the level of FT3 could provide prognostic value in patients with DCM.Methods:Data of consecutive patients diagnosed with DCM were collected from October 2009 to December 2014.FT3 was measured by fluoroimmunoassay.Other biochemical markers,such as free thyroxin(FT4),thyroid-stimulating hormone,red blood cell,hemoglobin,blood urea nitrogen,and serum creatinine,were tested at the same time.Follow-up was performed every 3 months.The primary endpoint was all-cause mortality.Pearson analysis was used to evaluate the correlation of FT3 and other lab metrics with DCM patients’prognosis.The association of long-term mortality in DCM and FT3 was compared using Cox hazards model.Results:Data of 176 patients diagnosed with DCM were collected.Of them,24 patients missed FT3 values and six patients were lost to follow-up.Altogether,data of 146 patients were analyzed.During the median follow-up time of 79.9(53.5-159.6)months,nine patients lost,61 patients died(non-survival group),and 85 patients survived(survival group).FT3 was significantly lower in non-survival group than that in survival group(3.65±0.83 pmol/L vs.4.36±1.91 pmol/L;P=0.003).FT3 also showed a significantly positive correlation with red blood cell and hemoglobin,negatively correlated with age,blood urea nitrogen and serum creatinine(P<0.05),respectively.Patients in the group of lower FT3 levels(FT3≤3.49 pmol/L)suffered from a higher risk of all-cause mortality(P for log-rank=0.001).In multivariate Cox regression analysis,FT3 level was significantly associated with all-cause mortality(hazard ratio:0.70,95%confidence interval 0.52-0.95,P for trend=0.021).Conclusion:Low levels of FT3 were associated with increased all-cause mortality in patients with DCM.
