Halide perovskites have emerged as the next generation of optoelectronic materials and their remarkable performances have been attractive in the fields of solar cells,light-emitting diodes,photodetectors,etc.In additi...Halide perovskites have emerged as the next generation of optoelectronic materials and their remarkable performances have been attractive in the fields of solar cells,light-emitting diodes,photodetectors,etc.In addition,halide perovskites have been reported as an attractive new class of X-ray direct detecting materials recently,owning to the strong X-ray stopping capacity,excellent carrier transport,high sensitivity,and cost-effective manufacturing.Meanwhile,perovskite based direct Xray imagers have been successfully demonstrated as well.In this review article,we firstly introduced some fundamental principles of direct X-ray detection and imaging,and summarized the advances of perovskite materials for these purposes and finally put forward some needful and feasible directions.展开更多
The traction characteristics of the grouser, cutting the simulative soil of deepsea sediment, with different tooth widths, tooth heights, and ground pressures are studied with traction characteristic test apparatus. A...The traction characteristics of the grouser, cutting the simulative soil of deepsea sediment, with different tooth widths, tooth heights, and ground pressures are studied with traction characteristic test apparatus. A traction-displacement model is obtained by combining the analysis of the cutting mechanism. The results show that the tractiondisplacement curves of grousers with different tooth widths, tooth heights, and ground pressures have the same changing trend, which matches the Wong traction model. Their sensitivity coefficient and shear modulus are slightly fluctuated. Therefore, the average values can be used as the traction model parameters. The maximum traction of the grouser with a two-side edge and a 10 mm tooth width increment changing with the tooth height and ground pressure can be determined according to the grousers with different tooth widths. By combining the traction model parameters, the traction-displacement curve of the grouser with a certain group values of tooth width, tooth height, and ground pressure can be predicted. Therefore, the slip of the mining machine can be prevented to improve the mining efficiency.展开更多
In our published letter,[1]we have identified a minor error in Figs.2 and 3.Instead,we have 2111 events in these two plots with 646,249,382,and 834 events in Run 9(20.0 ton·day),Run 10(19.4 ton·day),Run 11–...In our published letter,[1]we have identified a minor error in Figs.2 and 3.Instead,we have 2111 events in these two plots with 646,249,382,and 834 events in Run 9(20.0 ton·day),Run 10(19.4 ton·day),Run 11–1(24.2 ton·day),and Run 11–2(37.1 ton·day).The mistake is due to an incorrect application of a small energy non-linearity(known as the BLS non-linearity)in making plots,but has no impact to the final results.Figures 2 and 3 are now updated in this note.展开更多
We report a search for new physics signals using the low energy electron recoil events in the complete data set from PandaX-Ⅱ,in light of the recent event excess reported by XENON1 T.The data correspond to a total ex...We report a search for new physics signals using the low energy electron recoil events in the complete data set from PandaX-Ⅱ,in light of the recent event excess reported by XENON1 T.The data correspond to a total exposure of 100.7 ton·day with liquid xenon.With robust estimates of the dominant background spectra,we perform sensitive searches on solar axions and neutrinos with enhanced magnetic moment.It is found that the axionelectron coupling gAe<4.6×10^(-12) for an axion mass less than 0.1 keV/c^(2) and the neutrino magnetic moment μv<4.9×10^(-11)μB at 90%confidence level.The observed excess from XENON1 T is within our experimental constraints.展开更多
Due to the influence of deep-sea environment,deep-sea sediments are usually heterogeneous,and their moduli of elasticity and density change as depth changes.Combined with the characteristics of deep-sea sediments,the ...Due to the influence of deep-sea environment,deep-sea sediments are usually heterogeneous,and their moduli of elasticity and density change as depth changes.Combined with the characteristics of deep-sea sediments,the thermo-hydro-mechanical coupling dynamic response model of heterogeneous saturated porous sediments can be established to study the influence of elastic modulus,density,frequency,and load amplitude changes on the model.Based on the Green-Lindsay generalized thermoelasticity theory and Darcy’s law,the thermo-hydro-mechanical coupled dynamic response model and governing equations of heterogeneous deep-sea sediments with nonlinear elastic modulus and density are established.The analytical solutions of dimensionless vertical displacement,vertical stress,excess pore water pressure,and temperature are obtained by means of normal modal analysis,which are depicted graphically.The results show that the changes of elastic modulus and density have few effects on vertical displacement,vertical stress,and temperature,but have great effects on excess pore water pressure.When the mining machine vibrates,the heterogeneity of deep-sea sediments has great influence on vertical displacement,vertical stress,and excess pore water pressure,but has few effects on temperature.In addition,the vertical displacement,vertical stress,and excess pore water pressure of heterogeneous deep-sea sediments change more gently.The variation trends of physical quantities for heterogeneous and homogeneous deep-sea sediments with frequency and load amplitude are basically the same.The results can provide theoretical guidance for deep-sea mining engineering construction.展开更多
The excessive deformation of deep-sea sediments caused by the vibration of the mining machine will adversely affect the efficiency and safety of mining.Combined with the deep-sea environment,the coupled thermo-hydro-m...The excessive deformation of deep-sea sediments caused by the vibration of the mining machine will adversely affect the efficiency and safety of mining.Combined with the deep-sea environment,the coupled thermo-hydro-mechanical problem for saturated porous deep-sea sediments subject to the vibration of the mining vehicle is investigated.Based on the Green-Lindsay(G-L)generalized thermoelastic theory and Darcy’s law,the model of thermo-hydro-mechanical dynamic responses for saturated porous deep-sea sediments under the vibration of the mining vehicle is established.We obtain the analytical solutions of non-dimensional vertical displacement,excess pore water pressure,vertical stress,temperature,and change in the volume fraction field with the normal mode analysis method,and depict them graphically.The normal mode analysis method uses the canonical coordinate transformation to solve the equation,which can quickly decouple the equation by ignoring the modal coupling effect on the basis of the canonical mode.The results indicate that the vibration frequency has obvious influence on the vertical displacement,excess pore water pressure,vertical stress,and change in volume fraction field.The loading amplitude has a great effect on the physical quantities in the foundation,and the changes of the physical quantities increase with the increase in loading amplitude.展开更多
Based on the elementary solutions and new integral equations,a new analytical-numerical method is proposed to calculate the interacting stresses of multiple circular holes in an infinite elastic plate under both remot...Based on the elementary solutions and new integral equations,a new analytical-numerical method is proposed to calculate the interacting stresses of multiple circular holes in an infinite elastic plate under both remote stresses and arbitrarily distributed stresses applied to the circular boundaries.The validity of this new analytical-numerical method is verified by the analytical solution of the bi-harmonic stress function method,the numerical solution of the finite element method,and the analytical-numerical solutions of the series expansion and Laurent series methods.Some numerical examples are presented to investigate the effects of the hole geometry parameters(radii and relative positions)and loading conditions(remote stresses and surface stresses)on the interacting tangential stresses and interacting stress concentration factors(SCFs).The results show that whether the interference effect is shielding(k<1)or amplifying(k>1)depends on the relative orientation of holes(α)and remote stresses(σ^∞x,σ^∞y).When the maximum principal stress is aligned with the connecting line of two-hole centers andσ^∞y<0.5σ^∞x,the plate containing two circular holes has greater stability than that containing one circular hole,and the smaller circular hole has greater stability than the bigger one.This new method not only has a simple formulation and high accuracy,but also has an advantage of wide applications over common analytical methods and analytical-numerical methods in calculating the interacting stresses of a multi-hole problem under both remote and arbitrary surface stresses.展开更多
Dynamic host–pathogen interactions determine whether disease will occur.Pathogen effector proteins are central players in such disease development.On one hand,they improve susceptibility by manipulating host targets;...Dynamic host–pathogen interactions determine whether disease will occur.Pathogen effector proteins are central players in such disease development.On one hand,they improve susceptibility by manipulating host targets;on the other hand,they can trigger immunity after recognition by host immune receptors.A major research direction in the study of molecular plant pathology is to understand effector-host interactions,which has informed the development and breeding of crops with enhanced disease resistance.Recent breakthroughs on experiment-and artificial intelligence-based structure analyses significantly accelerate the development of this research area.Importantly,the detailed molecular insight of effector–host interactions enables precise engineering to mitigate disease.Here,we highlight a recent study by Xiao et al.,who describe the structure of an effector-receptor complex that consists of a fungal effector,with polygalacturonase(PG)activity,and a plant-derived polygalacturonase-inhibiting protein(PGIP).PGs weaken the plant cell wall and produce immune-suppressive oligogalacturonides(OGs)as a virulence mechanism;however,PGIPs directly bind to PGs and alter their enzymatic activity.When in a complex with PGIPs,PGs produce OG polymers with longer chains that can trigger immunity.Xiao et al.demonstrate that a PGIP creates a new active site tunnel,together with a PG,which favors the production of long-chain OGs.In this way,the PGIP essentially acts as both a PG receptor and enzymatic manipulator,converting virulence to defense activation.Taking a step forward,the authors used the PG-PGIP complex structure as a guide to generate PGIP variants with enhanced long-chain OG production,likely enabling further improved disease resistance.This study discovered a novel mechanism by which a plant receptor plays a dual role to activate immunity.It also demonstrates how fundamental knowledge,obtained through structural analyses,can be employed to guide the design of proteins with desired functions in agriculture.展开更多
Neutrinos from core-collapse supernovae are essential for understanding neutrino physics and stellar evolution.Dual-phase xenon dark matter detectors can be used to track explosions of galactic supernovae by detecting...Neutrinos from core-collapse supernovae are essential for understanding neutrino physics and stellar evolution.Dual-phase xenon dark matter detectors can be used to track explosions of galactic supernovae by detecting neutrinos through coherent elastic neutrino-nucleus scatterings.In this study,a variation of progenitor masses and explosion models are assumed to predict neutrino fluxes and spectra,which result in the number of expected neutrino events ranging from 6.6 to 13.7 at a distance of 10 kpc over a 10-s duration with negligible backgrounds at PandaX-4T.Two specialized triggering alarms for monitoring supernova burst neutrinos are built.The efficiency of detecting supernova explosions at various distances in the Milky Way is estimated.These alarms will be implemented in the real-time supernova monitoring system at PandaX-4T in the near future,which will provide supernova early warnings for the astronomical community.展开更多
The proton-proton(pp)fusion chain dominates the neutrino production in the Sun.The uncertainty of the predicted pp neutrino flux is at the sub-percent level,whereas that of the best measurement is O(10%).In this study...The proton-proton(pp)fusion chain dominates the neutrino production in the Sun.The uncertainty of the predicted pp neutrino flux is at the sub-percent level,whereas that of the best measurement is O(10%).In this study,for the first time,we measure solar pp neutrinos in the electron recoil energy range from 24 to 144 keV using the PandaX-4T commissioning data with 0.63 tonne×year exposure.The pp neutrino flux is determined as(8.0±3.9(stat)±10.0(syst))×1010 s^(-1)cm^(-2),which is consistent with the Standard Solar Model and existing measurements,corresponding to an upper flux limit of 23.3×10^(10)s^(-1)cm^(-2)at 90%C.L..展开更多
X-rays are widely used in probing inside information nondestructively,enabling broad applications in the medical radiography and electronic industries.X-ray imaging based on emerging lead halide perovskite scintillato...X-rays are widely used in probing inside information nondestructively,enabling broad applications in the medical radiography and electronic industries.X-ray imaging based on emerging lead halide perovskite scintillators has received extensive attention recently.However,the strong self-absorption,relatively low light yield and lead toxicity of these perovskites restrict their practical applications.Here,we report a series of nontoxic double-perovskite scintillators of Cs_(2)Ag_(0.6)Na_(0.4)In_(1-y)Bi_(y)Cl_(6).By controlling the content of the heavy atom Bi^(3+),the X-ray absorption coefficient,radiative emission efficiency,light yield and light decay were manipulated to maximise the scintillator performance.A light yield of up to 39,000±7000 photons/MeV for Cs_(2)Ag_(0.6)Na_(0.4)In_(0.85)Bi_(0.15)Cl_(6) was obtained,which is much higher than that for the previously reported lead halide perovskite colloidal CsPbBr_(3)(21,000 photons/MeV).The large Stokes shift between the radioluminescence(RL)and absorption spectra benefiting from self-trapped excitons(STEs)led to a negligible selfabsorption effect.Given the high light output and fast light decay of this scintillator,static X-ray imaging was attained under an extremely low dose of ∼1μGy_(air),and dynamic X-ray imaging of finger bending without a ghosting effect was demonstrated under a low-dose rate of 47.2μGy_(air) s^(−1).After thermal treatment at 85℃ for 50 h followed by X-ray irradiation for 50 h in ambient air,the scintillator performance in terms of the RL intensity and X-ray image quality remained almost unchanged.Our results shed light on exploring highly competitive scintillators beyond the scope of lead halide perovskites,not only for avoiding toxicity but also for better performance.展开更多
Self-interacting dark matter(SIDM)is a leading candidate proposed to solve discrepancies between predictions of the prevailing cold dark matter theory and observations of galaxies.Many SIDM models predict the existenc...Self-interacting dark matter(SIDM)is a leading candidate proposed to solve discrepancies between predictions of the prevailing cold dark matter theory and observations of galaxies.Many SIDM models predict the existence of a light force carrier that mediates strong dark matter self-interactions.If the mediator couples to the standard model particles,it could produce characteristic signals in dark matter direct detection experiments.We report searches for signals of SIDM models with a light mediator using the full dataset of the PandaX-II experiment,basing on a total exposure of 132 tonne-days.No significant excess over background is found,and our likelihood analysis leads to a strong upper limit on the dark matter-nucleon coupling strength.We further combine the PandaX-II constraints and those from observations of the light element abundances in the early universe,and show that direct detection and cosmological probes can provide complementary constraints on dark matter models with a light mediator.展开更多
We report the dark matter search results obtained using the full 132 ton·day exposure of the PandaX-II experiment,including all data from March 2016 to August 2018.No significant excess of events is identified ab...We report the dark matter search results obtained using the full 132 ton·day exposure of the PandaX-II experiment,including all data from March 2016 to August 2018.No significant excess of events is identified above the expected background.Upper limits are set on the spin-independent dark matter-nucleon interactions.The lowest 90%confidence level exclusion on the spin-independent cross section is 2.2×10−46 cm2 at a WIMP mass of 30 GeV/c2.展开更多
Precise measurement of two-neutrino double beta decay(DBD)half-life is an important step for the searches of Majorana neutrinos with neutrinoless double beta decay.We report the measurement of DBD half-life of 136xe u...Precise measurement of two-neutrino double beta decay(DBD)half-life is an important step for the searches of Majorana neutrinos with neutrinoless double beta decay.We report the measurement of DBD half-life of 136xe using the Pandax-4T dual-phase Time Projection Chamber(TPC)with 3.7-tonne natural xenon and the first 94.9-day physics data release.展开更多
We report the Neutrino-less Double Beta Decay(NLDBD) search results from PandaX-Ⅱ dual-phase liquid xenon time projection chamber.The total live time used in this analysis is 403.1 days from June 2016 to August2018...We report the Neutrino-less Double Beta Decay(NLDBD) search results from PandaX-Ⅱ dual-phase liquid xenon time projection chamber.The total live time used in this analysis is 403.1 days from June 2016 to August2018.With NLDBD-optimized event selection criteria,we obtain a fiducial mass of 219 kg of natural xenon.The accumulated xenon exposure is 242 kg yr,or equivalently 22.2 kg yr of 136Xe exposure.At the region around 136Xe decay Q-value of 2458 keV,the energy resolution of PandaX-Ⅱ is 4.2%.We find no evidence of NLDBD in PandaX-Ⅱand establish a lower limit for decay half-life of 2.1×1023yr at the 90% confidence level,which corresponds to an effective Majorana neutrino mass mββ <(1.4-3.7) eV.This is the first NLDBD result reported from a dual-phase xenon experiment.展开更多
In dark matter direct detection experiments,neutron is a serious source of background,which can mimic the dark matter-nucleus scattering signals.In this paper,we present an improved evaluation of the neutron backgroun...In dark matter direct detection experiments,neutron is a serious source of background,which can mimic the dark matter-nucleus scattering signals.In this paper,we present an improved evaluation of the neutron background in the PandaX-II dark matter experiment by a novel approach.Instead of fully relying on the Monte Carlo simulation,the overall neutron background is determined from the neutron-induced high energy signals in the data.In addition,the probability of producing a dark-matter-like background per neutron is evaluated with a complete Monte Carlo generator,where the correlated emission of neutron(s)andγ(s)in the(α,n)reactions and spontaneous fissions is taken into consideration.With this method,the neutron backgrounds in the Run 9(26-ton-day)and Run 10(28-ton-day)data sets of PandaX-II are estimated to be(0.66±0.24)and(0.47±0.25)events,respectively.展开更多
We present a systematic determination of the responses of PandaX-Ⅱ,a dual phase xenon time projection chamber detector,to low energy recoils.The electron recoil(ER) and nuclear recoil(NR) responses are calibrated,res...We present a systematic determination of the responses of PandaX-Ⅱ,a dual phase xenon time projection chamber detector,to low energy recoils.The electron recoil(ER) and nuclear recoil(NR) responses are calibrated,respectively,with injected tritiated methane or 220Rn source,and with 241Am-Be neutron source,in an energy range from 1-25 keV(ER) and 4-80 keV(NR),under the two drift fields,400 and 317 V/cm.An empirical model is used to fit the light yield and charge yield for both types of recoils.The best fit models can describe the calibration data significantly.The systematic uncertainties of the fitted models are obtained via statistical comparison to the data.展开更多
Ⅰ.INTRODUCTION The direct detection of dark matter particles,especially the weakly interacting massive particles(WIMPs),is being actively carried out by a couple of experiments worldwide[1].In recent years,the PandaX...Ⅰ.INTRODUCTION The direct detection of dark matter particles,especially the weakly interacting massive particles(WIMPs),is being actively carried out by a couple of experiments worldwide[1].In recent years,the PandaX-Ⅱ experiment located in the China Jinping Underground Laboratory(CJPL)[1-3],which uses the technology of dual phase liquid xenon time projection chambers(TPCs),has pushed the limits of the cross section between WIMPs and nucleons to a new level for most of the possible WIMP masses;other experiments of the same type are also being performed[4–10].展开更多
文摘Halide perovskites have emerged as the next generation of optoelectronic materials and their remarkable performances have been attractive in the fields of solar cells,light-emitting diodes,photodetectors,etc.In addition,halide perovskites have been reported as an attractive new class of X-ray direct detecting materials recently,owning to the strong X-ray stopping capacity,excellent carrier transport,high sensitivity,and cost-effective manufacturing.Meanwhile,perovskite based direct Xray imagers have been successfully demonstrated as well.In this review article,we firstly introduced some fundamental principles of direct X-ray detection and imaging,and summarized the advances of perovskite materials for these purposes and finally put forward some needful and feasible directions.
基金Project supported by the National Natural Science Foundation of China(No.51274251)
文摘The traction characteristics of the grouser, cutting the simulative soil of deepsea sediment, with different tooth widths, tooth heights, and ground pressures are studied with traction characteristic test apparatus. A traction-displacement model is obtained by combining the analysis of the cutting mechanism. The results show that the tractiondisplacement curves of grousers with different tooth widths, tooth heights, and ground pressures have the same changing trend, which matches the Wong traction model. Their sensitivity coefficient and shear modulus are slightly fluctuated. Therefore, the average values can be used as the traction model parameters. The maximum traction of the grouser with a two-side edge and a 10 mm tooth width increment changing with the tooth height and ground pressure can be determined according to the grousers with different tooth widths. By combining the traction model parameters, the traction-displacement curve of the grouser with a certain group values of tooth width, tooth height, and ground pressure can be predicted. Therefore, the slip of the mining machine can be prevented to improve the mining efficiency.
文摘In our published letter,[1]we have identified a minor error in Figs.2 and 3.Instead,we have 2111 events in these two plots with 646,249,382,and 834 events in Run 9(20.0 ton·day),Run 10(19.4 ton·day),Run 11–1(24.2 ton·day),and Run 11–2(37.1 ton·day).The mistake is due to an incorrect application of a small energy non-linearity(known as the BLS non-linearity)in making plots,but has no impact to the final results.Figures 2 and 3 are now updated in this note.
基金Supported in part by the National Key R&D Program of China(Grant No.2016YFA0400301)the National Natural Science Foundation of China(Grant Nos.11525522,11775141,and 11755001)+5 种基金the Double First Class Plan of the Shanghai Jiao Tong University,the China Postdoctoral Science Foundation(Grant No.2018M640036)the Office of Science and Technology,Shanghai Municipal Government(Grant Nos.11DZ2260700,16DZ2260200,and 18JC1410200)the Key Laboratory for Particle Physics,Astrophysics and Cosmology,Ministry of Education,for important supportsponsorship from the Chinese Academy of Sciences Center for Excellence in Particle Physics(CCEPP)the Hongwen Foundation in Hong Kongthe Tencent Foundation in China。
文摘We report a search for new physics signals using the low energy electron recoil events in the complete data set from PandaX-Ⅱ,in light of the recent event excess reported by XENON1 T.The data correspond to a total exposure of 100.7 ton·day with liquid xenon.With robust estimates of the dominant background spectra,we perform sensitive searches on solar axions and neutrinos with enhanced magnetic moment.It is found that the axionelectron coupling gAe<4.6×10^(-12) for an axion mass less than 0.1 keV/c^(2) and the neutrino magnetic moment μv<4.9×10^(-11)μB at 90%confidence level.The observed excess from XENON1 T is within our experimental constraints.
基金Project supported by the National Natural Science Foundation of China(Nos.12072309,61603322)。
文摘Due to the influence of deep-sea environment,deep-sea sediments are usually heterogeneous,and their moduli of elasticity and density change as depth changes.Combined with the characteristics of deep-sea sediments,the thermo-hydro-mechanical coupling dynamic response model of heterogeneous saturated porous sediments can be established to study the influence of elastic modulus,density,frequency,and load amplitude changes on the model.Based on the Green-Lindsay generalized thermoelasticity theory and Darcy’s law,the thermo-hydro-mechanical coupled dynamic response model and governing equations of heterogeneous deep-sea sediments with nonlinear elastic modulus and density are established.The analytical solutions of dimensionless vertical displacement,vertical stress,excess pore water pressure,and temperature are obtained by means of normal modal analysis,which are depicted graphically.The results show that the changes of elastic modulus and density have few effects on vertical displacement,vertical stress,and temperature,but have great effects on excess pore water pressure.When the mining machine vibrates,the heterogeneity of deep-sea sediments has great influence on vertical displacement,vertical stress,and excess pore water pressure,but has few effects on temperature.In addition,the vertical displacement,vertical stress,and excess pore water pressure of heterogeneous deep-sea sediments change more gently.The variation trends of physical quantities for heterogeneous and homogeneous deep-sea sediments with frequency and load amplitude are basically the same.The results can provide theoretical guidance for deep-sea mining engineering construction.
基金the National Natural Science Foundation of China(No.12072309)the Youth Fund Foundation of Education Bureau of Hunan Province of China(No.19B546)the High-Level Talent Gathering Project in Hunan Province of China(No.2019RS1059)。
文摘The excessive deformation of deep-sea sediments caused by the vibration of the mining machine will adversely affect the efficiency and safety of mining.Combined with the deep-sea environment,the coupled thermo-hydro-mechanical problem for saturated porous deep-sea sediments subject to the vibration of the mining vehicle is investigated.Based on the Green-Lindsay(G-L)generalized thermoelastic theory and Darcy’s law,the model of thermo-hydro-mechanical dynamic responses for saturated porous deep-sea sediments under the vibration of the mining vehicle is established.We obtain the analytical solutions of non-dimensional vertical displacement,excess pore water pressure,vertical stress,temperature,and change in the volume fraction field with the normal mode analysis method,and depict them graphically.The normal mode analysis method uses the canonical coordinate transformation to solve the equation,which can quickly decouple the equation by ignoring the modal coupling effect on the basis of the canonical mode.The results indicate that the vibration frequency has obvious influence on the vertical displacement,excess pore water pressure,vertical stress,and change in volume fraction field.The loading amplitude has a great effect on the physical quantities in the foundation,and the changes of the physical quantities increase with the increase in loading amplitude.
基金Project supported by the National Natural Science Foundation of China(Nos.51474251,51874351,and 11502226)the Natural Science Foundation of Hunan Province of China(No.2019JJ50625)and the Key Research and Development Plan of Hunan Province of China(No.2017WK2032)。
文摘Based on the elementary solutions and new integral equations,a new analytical-numerical method is proposed to calculate the interacting stresses of multiple circular holes in an infinite elastic plate under both remote stresses and arbitrarily distributed stresses applied to the circular boundaries.The validity of this new analytical-numerical method is verified by the analytical solution of the bi-harmonic stress function method,the numerical solution of the finite element method,and the analytical-numerical solutions of the series expansion and Laurent series methods.Some numerical examples are presented to investigate the effects of the hole geometry parameters(radii and relative positions)and loading conditions(remote stresses and surface stresses)on the interacting tangential stresses and interacting stress concentration factors(SCFs).The results show that whether the interference effect is shielding(k<1)or amplifying(k>1)depends on the relative orientation of holes(α)and remote stresses(σ^∞x,σ^∞y).When the maximum principal stress is aligned with the connecting line of two-hole centers andσ^∞y<0.5σ^∞x,the plate containing two circular holes has greater stability than that containing one circular hole,and the smaller circular hole has greater stability than the bigger one.This new method not only has a simple formulation and high accuracy,but also has an advantage of wide applications over common analytical methods and analytical-numerical methods in calculating the interacting stresses of a multi-hole problem under both remote and arbitrary surface stresses.
基金supported by Gatsby Charitable Foundation and UKRI BBSRC Grant BBS/E/J/000PR9797.
文摘Dynamic host–pathogen interactions determine whether disease will occur.Pathogen effector proteins are central players in such disease development.On one hand,they improve susceptibility by manipulating host targets;on the other hand,they can trigger immunity after recognition by host immune receptors.A major research direction in the study of molecular plant pathology is to understand effector-host interactions,which has informed the development and breeding of crops with enhanced disease resistance.Recent breakthroughs on experiment-and artificial intelligence-based structure analyses significantly accelerate the development of this research area.Importantly,the detailed molecular insight of effector–host interactions enables precise engineering to mitigate disease.Here,we highlight a recent study by Xiao et al.,who describe the structure of an effector-receptor complex that consists of a fungal effector,with polygalacturonase(PG)activity,and a plant-derived polygalacturonase-inhibiting protein(PGIP).PGs weaken the plant cell wall and produce immune-suppressive oligogalacturonides(OGs)as a virulence mechanism;however,PGIPs directly bind to PGs and alter their enzymatic activity.When in a complex with PGIPs,PGs produce OG polymers with longer chains that can trigger immunity.Xiao et al.demonstrate that a PGIP creates a new active site tunnel,together with a PG,which favors the production of long-chain OGs.In this way,the PGIP essentially acts as both a PG receptor and enzymatic manipulator,converting virulence to defense activation.Taking a step forward,the authors used the PG-PGIP complex structure as a guide to generate PGIP variants with enhanced long-chain OG production,likely enabling further improved disease resistance.This study discovered a novel mechanism by which a plant receptor plays a dual role to activate immunity.It also demonstrates how fundamental knowledge,obtained through structural analyses,can be employed to guide the design of proteins with desired functions in agriculture.
基金the National Natural Science Foundation of China(12090060,12090063,12105052,12005131,11905128,11925502)the Office of Science and Technology,Shanghai Municipal Government,China(22JC1410100)。
文摘Neutrinos from core-collapse supernovae are essential for understanding neutrino physics and stellar evolution.Dual-phase xenon dark matter detectors can be used to track explosions of galactic supernovae by detecting neutrinos through coherent elastic neutrino-nucleus scatterings.In this study,a variation of progenitor masses and explosion models are assumed to predict neutrino fluxes and spectra,which result in the number of expected neutrino events ranging from 6.6 to 13.7 at a distance of 10 kpc over a 10-s duration with negligible backgrounds at PandaX-4T.Two specialized triggering alarms for monitoring supernova burst neutrinos are built.The efficiency of detecting supernova explosions at various distances in the Milky Way is estimated.These alarms will be implemented in the real-time supernova monitoring system at PandaX-4T in the near future,which will provide supernova early warnings for the astronomical community.
基金supported in part by the grants from the National Science Foundation of China(12090060,12090063,12105052,12005131,11905128,11925502)the Office of Science and Technology,Shanghai Municipal Government(22JC1410100)+6 种基金the National Science Foundation of Sichuan ProvinceChina(2024NSFSC1371)the support from the Double First Class Plan of Shanghai Jiao Tong Universitythe sponsorship from the Chinese Academy of Sciences Center for Excellence in Particle Physics(CCEPP)Hongwen Foundation in Hong KongTencentNew Cornerstone Science Foundation in China。
文摘The proton-proton(pp)fusion chain dominates the neutrino production in the Sun.The uncertainty of the predicted pp neutrino flux is at the sub-percent level,whereas that of the best measurement is O(10%).In this study,for the first time,we measure solar pp neutrinos in the electron recoil energy range from 24 to 144 keV using the PandaX-4T commissioning data with 0.63 tonne×year exposure.The pp neutrino flux is determined as(8.0±3.9(stat)±10.0(syst))×1010 s^(-1)cm^(-2),which is consistent with the Standard Solar Model and existing measurements,corresponding to an upper flux limit of 23.3×10^(10)s^(-1)cm^(-2)at 90%C.L..
基金the support from the National Key Research and Development Program of China(2017YFA0207700)Outstanding Youth Fund of Zhejiang Natural Science Foundation of China(LR18F050001)National Natural Science Foundation of China(61804134,61525106,U1809204).
文摘X-rays are widely used in probing inside information nondestructively,enabling broad applications in the medical radiography and electronic industries.X-ray imaging based on emerging lead halide perovskite scintillators has received extensive attention recently.However,the strong self-absorption,relatively low light yield and lead toxicity of these perovskites restrict their practical applications.Here,we report a series of nontoxic double-perovskite scintillators of Cs_(2)Ag_(0.6)Na_(0.4)In_(1-y)Bi_(y)Cl_(6).By controlling the content of the heavy atom Bi^(3+),the X-ray absorption coefficient,radiative emission efficiency,light yield and light decay were manipulated to maximise the scintillator performance.A light yield of up to 39,000±7000 photons/MeV for Cs_(2)Ag_(0.6)Na_(0.4)In_(0.85)Bi_(0.15)Cl_(6) was obtained,which is much higher than that for the previously reported lead halide perovskite colloidal CsPbBr_(3)(21,000 photons/MeV).The large Stokes shift between the radioluminescence(RL)and absorption spectra benefiting from self-trapped excitons(STEs)led to a negligible selfabsorption effect.Given the high light output and fast light decay of this scintillator,static X-ray imaging was attained under an extremely low dose of ∼1μGy_(air),and dynamic X-ray imaging of finger bending without a ghosting effect was demonstrated under a low-dose rate of 47.2μGy_(air) s^(−1).After thermal treatment at 85℃ for 50 h followed by X-ray irradiation for 50 h in ambient air,the scintillator performance in terms of the RL intensity and X-ray image quality remained almost unchanged.Our results shed light on exploring highly competitive scintillators beyond the scope of lead halide perovskites,not only for avoiding toxicity but also for better performance.
基金This work was supported by a Double Top-class grant from Shanghai Jiao Tong University,and the National Natural Science Foundation of China(Grant No.11875190)Department of Energy(Grant No.de-sc0008541)the John Templeton Foundation(Grant No.#61884).
文摘Self-interacting dark matter(SIDM)is a leading candidate proposed to solve discrepancies between predictions of the prevailing cold dark matter theory and observations of galaxies.Many SIDM models predict the existence of a light force carrier that mediates strong dark matter self-interactions.If the mediator couples to the standard model particles,it could produce characteristic signals in dark matter direct detection experiments.We report searches for signals of SIDM models with a light mediator using the full dataset of the PandaX-II experiment,basing on a total exposure of 132 tonne-days.No significant excess over background is found,and our likelihood analysis leads to a strong upper limit on the dark matter-nucleon coupling strength.We further combine the PandaX-II constraints and those from observations of the light element abundances in the early universe,and show that direct detection and cosmological probes can provide complementary constraints on dark matter models with a light mediator.
基金Supported by a Double Top-class grant from Shanghai Jiao Tong University,grants from National Science Foundation of China(11435008,11525522,11775141,11755001)a grant from the Ministry of Science and Technology of China(2016YFA0400301)the Office of Science and Technology,Shanghai Municipal Government(11DZ2260700,16DZ2260200,18JC1410200)。
文摘We report the dark matter search results obtained using the full 132 ton·day exposure of the PandaX-II experiment,including all data from March 2016 to August 2018.No significant excess of events is identified above the expected background.Upper limits are set on the spin-independent dark matter-nucleon interactions.The lowest 90%confidence level exclusion on the spin-independent cross section is 2.2×10−46 cm2 at a WIMP mass of 30 GeV/c2.
基金This project is supported in part by grants from the Ministry of Science and Technology of China(No.2016YFA0400301 and 2016YFA0400302)grants from National Science Foundation of China(Nos.12090061,12090062,12005131,11905128,and 11925502)by Office of Science and Technology,Shanghai Municipal Government(grant No.18JC1410200).
文摘Precise measurement of two-neutrino double beta decay(DBD)half-life is an important step for the searches of Majorana neutrinos with neutrinoless double beta decay.We report the measurement of DBD half-life of 136xe using the Pandax-4T dual-phase Time Projection Chamber(TPC)with 3.7-tonne natural xenon and the first 94.9-day physics data release.
基金Supported by grants from the Ministry of Science and Technology of China(2016YFA0400301,2016YFA0400302)a Double Top-class grant from Shanghai Jiao Tong University,grants from National Science Foundation of China(11435008,11505112,11525522,11775142,11755001)+3 种基金grants from the Office of Science and Technology,Shanghai Municipal Government(11DZ2260700,16DZ2260200,18JC1410200)the support from the Key Laboratory for Particle Physics,Astrophysics and Cosmology,Ministry of Educationsupported in part by the Chinese Academy of Sciences Center for Excellence in Particle Physics(CCEPP)Hongwen Foundation in Hong Kong
文摘We report the Neutrino-less Double Beta Decay(NLDBD) search results from PandaX-Ⅱ dual-phase liquid xenon time projection chamber.The total live time used in this analysis is 403.1 days from June 2016 to August2018.With NLDBD-optimized event selection criteria,we obtain a fiducial mass of 219 kg of natural xenon.The accumulated xenon exposure is 242 kg yr,or equivalently 22.2 kg yr of 136Xe exposure.At the region around 136Xe decay Q-value of 2458 keV,the energy resolution of PandaX-Ⅱ is 4.2%.We find no evidence of NLDBD in PandaX-Ⅱand establish a lower limit for decay half-life of 2.1×1023yr at the 90% confidence level,which corresponds to an effective Majorana neutrino mass mββ <(1.4-3.7) eV.This is the first NLDBD result reported from a dual-phase xenon experiment.
基金supported by the Double Top-class of Shanghai Jiao Tong University,the National Natural Science Foundation of China(Grant Nos.11435008,11505112,11525522,11775141,and 11755001)the Ministry of Science and Technology of China(Grant No.2016YFA0400301)+4 种基金the Office of Science and Technology,Shanghai Municipal Government(Grant Nos.11DZ2260700,16DZ2260200,and 18JC1410200)the Key Laboratory for Particle Physics,Astrophysics and Cosmology,Ministry of Education,for important supportthe Chinese Academy of Sciences Center for Excellence in Particle Physics(CCEPP)Hongwen Foundation in Hong Kongwe thank the CJPL administration and the Yalong River Hydropower Development Company Ltd.for indispensable logistical support and other help.
文摘In dark matter direct detection experiments,neutron is a serious source of background,which can mimic the dark matter-nucleus scattering signals.In this paper,we present an improved evaluation of the neutron background in the PandaX-II dark matter experiment by a novel approach.Instead of fully relying on the Monte Carlo simulation,the overall neutron background is determined from the neutron-induced high energy signals in the data.In addition,the probability of producing a dark-matter-like background per neutron is evaluated with a complete Monte Carlo generator,where the correlated emission of neutron(s)andγ(s)in the(α,n)reactions and spontaneous fissions is taken into consideration.With this method,the neutron backgrounds in the Run 9(26-ton-day)and Run 10(28-ton-day)data sets of PandaX-II are estimated to be(0.66±0.24)and(0.47±0.25)events,respectively.
基金Supported by a grant from the Ministry of Science and Technology of China(2016YFA0400301)National Science Foundation of China(12090060,11525522,11775141,11755001)Office of Science and Technology,Shanghai Municipal Government(18JC1410200)。
文摘We present a systematic determination of the responses of PandaX-Ⅱ,a dual phase xenon time projection chamber detector,to low energy recoils.The electron recoil(ER) and nuclear recoil(NR) responses are calibrated,respectively,with injected tritiated methane or 220Rn source,and with 241Am-Be neutron source,in an energy range from 1-25 keV(ER) and 4-80 keV(NR),under the two drift fields,400 and 317 V/cm.An empirical model is used to fit the light yield and charge yield for both types of recoils.The best fit models can describe the calibration data significantly.The systematic uncertainties of the fitted models are obtained via statistical comparison to the data.
基金Supported in part by a grant from the Ministry of Science and Technology of China(2016YFA0400301)National Science Foundation of China(12090060,12005131,11905128,11925502,11775141)Office of Science and Technology,Shanghai Municipal Government(18JC1410200)。
文摘Ⅰ.INTRODUCTION The direct detection of dark matter particles,especially the weakly interacting massive particles(WIMPs),is being actively carried out by a couple of experiments worldwide[1].In recent years,the PandaX-Ⅱ experiment located in the China Jinping Underground Laboratory(CJPL)[1-3],which uses the technology of dual phase liquid xenon time projection chambers(TPCs),has pushed the limits of the cross section between WIMPs and nucleons to a new level for most of the possible WIMP masses;other experiments of the same type are also being performed[4–10].