High-amylose maize starch has great pote ntial for widespread in dustrial use due to its ability to form strong gels and film and in the food processi ng field,thus servi ng as a resista nt starch source.However,there...High-amylose maize starch has great pote ntial for widespread in dustrial use due to its ability to form strong gels and film and in the food processi ng field,thus servi ng as a resista nt starch source.However,there is still a substa ntial shortage of high-amylose maize due to the limitation of natural germplasm resources,although the well-known amylose extender(ae)gene mutants have bee n found to produce high-amylose maize lines since 1948.In this con text,high-amylose maize lines(13 inbreds and 18 hybrids)originating from a natural amylose mutant in our testing field were utilized to study the correlation between amylose content(AC)and phenotypic traits(kernel morphology and endosperm glossiness),grain filling characteristics,gene expression,and amylose inheritanee.Our results showed that AC was negatively correlated with total starch con tent but was not correlated with grain phe no types,such as kernel full ness,kernel morphology and endosperm glossiness.Maize lines with higher amylose had a greater grain filling rate than that of the controI(B73)during the first 20 days after pollination(DAP).Both starch debranching enzyme(DBE)groups and starch branching enzyme lib(SBEIIb)groups showed a greater abundance in the control(B73)than in the high-amylose maize lines.Male parents directly predicted AC of Fv which was moderately positively correlated with the F2 generation.展开更多
Objective:To systematically evaluate the efficacy of traditional Chinese medicine decoction combined with arthroscopy in the treatment of gouty arthritis.Methods:A systematic search of CNKI,CBM,WanFang,VIP,PubMed,Coch...Objective:To systematically evaluate the efficacy of traditional Chinese medicine decoction combined with arthroscopy in the treatment of gouty arthritis.Methods:A systematic search of CNKI,CBM,WanFang,VIP,PubMed,Cochrane Library,and EMBASE databases,and the receipt of the database until February 2021.Randomized controlled trials(RCTs)of traditional Chinese medicine(TCM)decoction combined with arthroscopy in the treatment of gouty arthritis.Two researchers independently read the title and abstract to screen and them read the full text to clarify whether it should be included.The method of Cochrane systematic review was used to evaluate the quality of the literature,and the RevMan 5.3 software was used to conduct meta-analysis of the data.Results:Nineteen RCTs were finally included.A total of 1383 patients,697 cases in the treatment group were treated with traditional Chinese medicine decoction combined with arthroscopy,and 686 cases in the control group were treated with arthroscopy alone or combined with western medicine.Meta-analysis results showed that the total clinical effective rate(P<0.00001)of the treatment group was better than that of the control group.Visual analogue scoring(VAS)score(P=0.0005,P<0.00001,P=0.03)and erythrocyte sedimentation rate(ESR)level(P<0.00001,P<0.00001,P<0.00001)reduction in each subgroup was better than that of the control group.The Lysholm score of the treatment group increased(P<0.00001,P<0.00001,P=0.19),while for blood uric acid(UA)level(P<0.00001,P=0.18,P<0.0001)and C-reactive protein(CRP)levels(P<0.0001,P<0.00001,P=0.23)two subgroups were better than the control group,but there was no significant difference in one subgroup.Conclusion:Traditional Chinese medicine decoction combined with arthroscopy is effective in treating gouty arthritis,which can relieve pain,improve joint function,and reduce body inflammation and uric acid levels.However,in the future,clinical studies with larger sample sizes,more reasonable designs,and higher quality are still needed to demonstrate this conclusion.展开更多
基金This work was supported by the National Key Research and Development Program of China(2017YFD0300304),the Sci-Tech Project of Yangling City,China(2014NY-01),the Tang Foundation,China(A212021205),and the Shaanxi Science&Technology Co-ordination&Innovation Project,China(2015KTZDNY01-01-01).
文摘High-amylose maize starch has great pote ntial for widespread in dustrial use due to its ability to form strong gels and film and in the food processi ng field,thus servi ng as a resista nt starch source.However,there is still a substa ntial shortage of high-amylose maize due to the limitation of natural germplasm resources,although the well-known amylose extender(ae)gene mutants have bee n found to produce high-amylose maize lines since 1948.In this con text,high-amylose maize lines(13 inbreds and 18 hybrids)originating from a natural amylose mutant in our testing field were utilized to study the correlation between amylose content(AC)and phenotypic traits(kernel morphology and endosperm glossiness),grain filling characteristics,gene expression,and amylose inheritanee.Our results showed that AC was negatively correlated with total starch con tent but was not correlated with grain phe no types,such as kernel full ness,kernel morphology and endosperm glossiness.Maize lines with higher amylose had a greater grain filling rate than that of the controI(B73)during the first 20 days after pollination(DAP).Both starch debranching enzyme(DBE)groups and starch branching enzyme lib(SBEIIb)groups showed a greater abundance in the control(B73)than in the high-amylose maize lines.Male parents directly predicted AC of Fv which was moderately positively correlated with the F2 generation.
基金National Natural Science Foundation of China(No.82060871,81860857)。
文摘Objective:To systematically evaluate the efficacy of traditional Chinese medicine decoction combined with arthroscopy in the treatment of gouty arthritis.Methods:A systematic search of CNKI,CBM,WanFang,VIP,PubMed,Cochrane Library,and EMBASE databases,and the receipt of the database until February 2021.Randomized controlled trials(RCTs)of traditional Chinese medicine(TCM)decoction combined with arthroscopy in the treatment of gouty arthritis.Two researchers independently read the title and abstract to screen and them read the full text to clarify whether it should be included.The method of Cochrane systematic review was used to evaluate the quality of the literature,and the RevMan 5.3 software was used to conduct meta-analysis of the data.Results:Nineteen RCTs were finally included.A total of 1383 patients,697 cases in the treatment group were treated with traditional Chinese medicine decoction combined with arthroscopy,and 686 cases in the control group were treated with arthroscopy alone or combined with western medicine.Meta-analysis results showed that the total clinical effective rate(P<0.00001)of the treatment group was better than that of the control group.Visual analogue scoring(VAS)score(P=0.0005,P<0.00001,P=0.03)and erythrocyte sedimentation rate(ESR)level(P<0.00001,P<0.00001,P<0.00001)reduction in each subgroup was better than that of the control group.The Lysholm score of the treatment group increased(P<0.00001,P<0.00001,P=0.19),while for blood uric acid(UA)level(P<0.00001,P=0.18,P<0.0001)and C-reactive protein(CRP)levels(P<0.0001,P<0.00001,P=0.23)two subgroups were better than the control group,but there was no significant difference in one subgroup.Conclusion:Traditional Chinese medicine decoction combined with arthroscopy is effective in treating gouty arthritis,which can relieve pain,improve joint function,and reduce body inflammation and uric acid levels.However,in the future,clinical studies with larger sample sizes,more reasonable designs,and higher quality are still needed to demonstrate this conclusion.
