This article provides an overview of underwater sound-absorbing materials mainly applied with polyurethane matrix.It mainly elaborates on the underwater sound mecha-nism,commonly used underwater sound-absorbing materi...This article provides an overview of underwater sound-absorbing materials mainly applied with polyurethane matrix.It mainly elaborates on the underwater sound mecha-nism,commonly used underwater sound-absorbing materials and structures,as well as new underwater sound-absorbing material structures derived from local resonance pho-nonic crystals,such as phononic crystals,local resonance phonon wood piles,and meta-material sound-absorbing structures.This provides a broader development space and direction for the future development of underwater sound-absorbing materials.展开更多
Dear editor,In 2016,several landmark government initiatives were launched in an effort to build a more healthy China.In March,the National People’s Congress of China adopted the 13th FiveYear Plan,which sets out new ...Dear editor,In 2016,several landmark government initiatives were launched in an effort to build a more healthy China.In March,the National People’s Congress of China adopted the 13th FiveYear Plan,which sets out new objectives,principles,and targets for 2016–2020,1including action plans for enhancing environmental protection and green growth,promoting individual展开更多
Research situation of eco-design is analyzed, and then thoughts and methods of eco-design are discused. The eco-design includes packaging modularization, dematerialization, energy-saving and bio-simulation.
Background and Aims:Protein phosphatase 2A(PP2A)is associated with many cancers.This study aimed to clarify whether PPP2CA,which encodes the alpha isoform of the catalytic subunit of PP2A,plays a role in hepatocellula...Background and Aims:Protein phosphatase 2A(PP2A)is associated with many cancers.This study aimed to clarify whether PPP2CA,which encodes the alpha isoform of the catalytic subunit of PP2A,plays a role in hepatocellular carcinoma(HCC)and to identify the potential underlying molecular pathways.Methods:Based on bioinformatics,public databases and our in-house RNA-Seq database,we analyzed the clinical value and molecular mechanism of PPP2CA in HCC.Results:Data were analyzed from 2,545 patients with HCC and 1,993 controls without HCC indexed in The Cancer Genome Atlas database,the Gene Expression Omnibus database and our in-house RNA-Seq database.PPP2CA expression was significantly higher in HCC tissue than in non-cancerous tissues(standardized mean difference:0.69,95%confidence interval[CI]:0.50–0.89).PPP2CA expression was able to differentiate HCC from non-HCC,with an area under the summary receiver operator characteristic curve of 0.79(95%CI:0.75–0.83).Immunohistochemistry of tissue sections confirmed that PPP2CA protein was up-regulated in HCC tissues.High PPP2CA expression in HCC patients was associated with shorter overall,progression-free and disease-free survival.Potential molecular pathways through which PPP2CA may be involved in HCC were determined using miRWalk 2.0 as well as analysis of Gene Ontology categories,Kyoto Encyclopedia of Genes and Genomes pathways,and protein-protein interaction networks.Conclusions:PPP2CA is up-regulated in HCC and higher expression correlates with worse prognosis.PPP2CA shows potential as a diagnostic marker for HCC.Future studies should examine whether PPP2CA contributes to HCC through the candidate microRNAs,pathways and hub genes identified in this study.展开更多
文摘This article provides an overview of underwater sound-absorbing materials mainly applied with polyurethane matrix.It mainly elaborates on the underwater sound mecha-nism,commonly used underwater sound-absorbing materials and structures,as well as new underwater sound-absorbing material structures derived from local resonance pho-nonic crystals,such as phononic crystals,local resonance phonon wood piles,and meta-material sound-absorbing structures.This provides a broader development space and direction for the future development of underwater sound-absorbing materials.
基金supported by China Institute of Sport Science(No.16-16,16-53)
文摘Dear editor,In 2016,several landmark government initiatives were launched in an effort to build a more healthy China.In March,the National People’s Congress of China adopted the 13th FiveYear Plan,which sets out new objectives,principles,and targets for 2016–2020,1including action plans for enhancing environmental protection and green growth,promoting individual
基金Supported by Jiangsu Province Scientific Innovation Research of College Graduate
文摘Research situation of eco-design is analyzed, and then thoughts and methods of eco-design are discused. The eco-design includes packaging modularization, dematerialization, energy-saving and bio-simulation.
基金This research was supported by the Innovation and Entrepreneurship Training Program for College Students of Guangxi Medical University(202010598047)the China Postdoctoral Science Foundation(2019M663876XB)+2 种基金the National Natural Science Foundation of China(81960450,82060510)the‘Guangxi BaGui Scholars’Special Fund(2019AQ20)the National Major Special Science and Technology Project(2017ZX10203207).
文摘Background and Aims:Protein phosphatase 2A(PP2A)is associated with many cancers.This study aimed to clarify whether PPP2CA,which encodes the alpha isoform of the catalytic subunit of PP2A,plays a role in hepatocellular carcinoma(HCC)and to identify the potential underlying molecular pathways.Methods:Based on bioinformatics,public databases and our in-house RNA-Seq database,we analyzed the clinical value and molecular mechanism of PPP2CA in HCC.Results:Data were analyzed from 2,545 patients with HCC and 1,993 controls without HCC indexed in The Cancer Genome Atlas database,the Gene Expression Omnibus database and our in-house RNA-Seq database.PPP2CA expression was significantly higher in HCC tissue than in non-cancerous tissues(standardized mean difference:0.69,95%confidence interval[CI]:0.50–0.89).PPP2CA expression was able to differentiate HCC from non-HCC,with an area under the summary receiver operator characteristic curve of 0.79(95%CI:0.75–0.83).Immunohistochemistry of tissue sections confirmed that PPP2CA protein was up-regulated in HCC tissues.High PPP2CA expression in HCC patients was associated with shorter overall,progression-free and disease-free survival.Potential molecular pathways through which PPP2CA may be involved in HCC were determined using miRWalk 2.0 as well as analysis of Gene Ontology categories,Kyoto Encyclopedia of Genes and Genomes pathways,and protein-protein interaction networks.Conclusions:PPP2CA is up-regulated in HCC and higher expression correlates with worse prognosis.PPP2CA shows potential as a diagnostic marker for HCC.Future studies should examine whether PPP2CA contributes to HCC through the candidate microRNAs,pathways and hub genes identified in this study.
