Objective:To investigate the effects of intravenous thrombolysis therapy with alteplase on neurological function,coagulation function and serum inflammatory factors in patients with acute cerebral infarction.Methods:A...Objective:To investigate the effects of intravenous thrombolysis therapy with alteplase on neurological function,coagulation function and serum inflammatory factors in patients with acute cerebral infarction.Methods:A total of 96 patients with acute cerebral infarction admitted to our hospital from September 2017 to October 2019 were randomly divided into two groups,with 48 patients in each group.The control group(n=48)received routine treatment,and the observation group received intravenous thrombolysis therapy with alteplase on the basis of routine treatment.The neurological deficit score,prothrombin time(PT),activated partial thromboplastin time(APTT),tumor necrosis factor-a level(TNF-α),and high-sensitivity C-reactive protein(hs-CRP)were compared between the two groups after 15 days of treatment.Results:After treatment,NIHSS scores in both groups were lower than those before treatment;PT levels were increased,while APTT,TNF-αand hs-CRP levels were all decreased in both groups,and the changes in the observation group were greater than those in the control group,with statistically significant difference(P<0.05).Conclusions:Intravenous thrombolysis therapy with alteplase can improve the neurological function,coagulation function and serum levels of inflammatory factors in patients with acute cerebral infarction,which is worthy of clinical application.展开更多
Oxychloride titanium oxide precursor material is one of the key substances produced by the giant electrorheological effect. In this paper, tetrabutyl titanate and oxalic acid and anhydrous ethanol are used to prepare ...Oxychloride titanium oxide precursor material is one of the key substances produced by the giant electrorheological effect. In this paper, tetrabutyl titanate and oxalic acid and anhydrous ethanol are used to prepare porous titanyl oxalate precursor powder by precipitation method. The materials, morphology and grain size were analyzed by X-ray diffraction and electron microscope method. Conductivity was measured by a four-probe method, and then the infiltration property of water and silicone oil on the surface of the powder was investigated. The results show that Oxychloride titanium oxide precursor has good wettability to water and silicone oil. The wettability has little to do with the bath temperature and the pH of the solution. The contact angle of water on oxychloride titanium oxide precursor surface does not change greatly with the change of the bath temperature and pH, ranging from 26.8? to 31.1?. Similarly, the contact angle of silicone oil on the surface of the sample ranges from 9.5? to 11.5?. So, silicone oil has better wettability on the surface of the sample than water. Porous titanium oxalate is an insulating material having a resistivity more than 1 GΩ?cm. Oxychloride titanium oxide precursor is poor thermal stability, and it breaks down to generate TiO2 when the temperature is higher than 70?C.展开更多
Objective:To investigate the clinical effect of Xingnaojing injection combined with craniocerebral hypothermia apparatus in the treatment of acute hemorrhagic stroke.Methods:Seventy-two patients with acute hemorrhagic...Objective:To investigate the clinical effect of Xingnaojing injection combined with craniocerebral hypothermia apparatus in the treatment of acute hemorrhagic stroke.Methods:Seventy-two patients with acute hemorrhagic stroke admitted to our hospital from March 2018 to September 2019 were randomly divided into two groups,with 36 cases in each group.The control group(n=36)was treated with craniocerebral hypothermia apparatus,and the observation group(n=36)was treated with Xingnaojing injection combined with craniocerebral hypothermia apparatus.The clinical efficacy,the National Institutes of Health Stroke Scale(NIHSS)score and the activity of daily living(MBI score)after 1 month of treatment were compared.Results:The effective rate of treatment in the observation group was higher than that in the control group(P<0.05);NIHSS score was decreased in both groups(P<0.05);MBI score was increased in both groups,and the change range of the observation group was greater than that of the control group,showing statistically significant differences(P<0.05).Conclusion:Xingnaojing injection combined with craniocerebral hypothermia apparatus can improve the clinical efficacy,the neurological impairment and activity of daily living in the treatment of acute hemorrhagic stroke,which is worthy of clinical application.展开更多
文摘Objective:To investigate the effects of intravenous thrombolysis therapy with alteplase on neurological function,coagulation function and serum inflammatory factors in patients with acute cerebral infarction.Methods:A total of 96 patients with acute cerebral infarction admitted to our hospital from September 2017 to October 2019 were randomly divided into two groups,with 48 patients in each group.The control group(n=48)received routine treatment,and the observation group received intravenous thrombolysis therapy with alteplase on the basis of routine treatment.The neurological deficit score,prothrombin time(PT),activated partial thromboplastin time(APTT),tumor necrosis factor-a level(TNF-α),and high-sensitivity C-reactive protein(hs-CRP)were compared between the two groups after 15 days of treatment.Results:After treatment,NIHSS scores in both groups were lower than those before treatment;PT levels were increased,while APTT,TNF-αand hs-CRP levels were all decreased in both groups,and the changes in the observation group were greater than those in the control group,with statistically significant difference(P<0.05).Conclusions:Intravenous thrombolysis therapy with alteplase can improve the neurological function,coagulation function and serum levels of inflammatory factors in patients with acute cerebral infarction,which is worthy of clinical application.
文摘Oxychloride titanium oxide precursor material is one of the key substances produced by the giant electrorheological effect. In this paper, tetrabutyl titanate and oxalic acid and anhydrous ethanol are used to prepare porous titanyl oxalate precursor powder by precipitation method. The materials, morphology and grain size were analyzed by X-ray diffraction and electron microscope method. Conductivity was measured by a four-probe method, and then the infiltration property of water and silicone oil on the surface of the powder was investigated. The results show that Oxychloride titanium oxide precursor has good wettability to water and silicone oil. The wettability has little to do with the bath temperature and the pH of the solution. The contact angle of water on oxychloride titanium oxide precursor surface does not change greatly with the change of the bath temperature and pH, ranging from 26.8? to 31.1?. Similarly, the contact angle of silicone oil on the surface of the sample ranges from 9.5? to 11.5?. So, silicone oil has better wettability on the surface of the sample than water. Porous titanium oxalate is an insulating material having a resistivity more than 1 GΩ?cm. Oxychloride titanium oxide precursor is poor thermal stability, and it breaks down to generate TiO2 when the temperature is higher than 70?C.
文摘Objective:To investigate the clinical effect of Xingnaojing injection combined with craniocerebral hypothermia apparatus in the treatment of acute hemorrhagic stroke.Methods:Seventy-two patients with acute hemorrhagic stroke admitted to our hospital from March 2018 to September 2019 were randomly divided into two groups,with 36 cases in each group.The control group(n=36)was treated with craniocerebral hypothermia apparatus,and the observation group(n=36)was treated with Xingnaojing injection combined with craniocerebral hypothermia apparatus.The clinical efficacy,the National Institutes of Health Stroke Scale(NIHSS)score and the activity of daily living(MBI score)after 1 month of treatment were compared.Results:The effective rate of treatment in the observation group was higher than that in the control group(P<0.05);NIHSS score was decreased in both groups(P<0.05);MBI score was increased in both groups,and the change range of the observation group was greater than that of the control group,showing statistically significant differences(P<0.05).Conclusion:Xingnaojing injection combined with craniocerebral hypothermia apparatus can improve the clinical efficacy,the neurological impairment and activity of daily living in the treatment of acute hemorrhagic stroke,which is worthy of clinical application.