Supercapacitor is an efficient energy storage device,yet its wider application is still limited by self-discharge.Currently,various composite materials have been reported to have improved inhibition on self-discharge,...Supercapacitor is an efficient energy storage device,yet its wider application is still limited by self-discharge.Currently,various composite materials have been reported to have improved inhibition on self-discharge,while the evaluation of the synergistic effect in composite materials is challenging.Herein,pairs of intercalation type pseudocapacitive niobium oxides are pre-lithiated and coupled to construct conjugatedly configured supercapacitors,within which the cathode and anode experience identical reaction environment with single type of charge carrier,thus providing ideal platform to quantify the synergistic effect of composite materials on the self-discharge process.By using titanium dioxide as the stabilizer,we have compared how the modes of forming composite would influence the selfdischarge performance of the active composite materials with similar ratio of the constituent materials.Specifically,core@shell Nb_(2)O_(5)@TiO_(2) composite using TiO_(2) as the shell shows significantly higher synergy coefficient(μ=0.61,defined as the value that evaluates the synergistic effect between composite materials,and can be quantified using the overall performance of the composite,performance of individual component as well as the ratio of the component.) than other control group samples,which corresponds to the highest retained energy of 63% at 100 h.This work is expected to provide a general method for quantifying the synergistic effect and guide the design of composite materials with specific mode of forming the composite.展开更多
According to the characteristic of huge thick loose layer in Huainan mining area, based on the measured data, the correlation between the relative parameters of coal pillar setting and the ratio of loose layer thickne...According to the characteristic of huge thick loose layer in Huainan mining area, based on the measured data, the correlation between the relative parameters of coal pillar setting and the ratio of loose layer thickness to mining depth in Huainan mining area under the mining condition of huge thick loose layer was mainly studied by using regression analysis method, and corresponding mathematical models were established and analyzed. It makes a theoretical supplement for the the analysis and research of mining subsidence rules in Huainan mining area under the condition of huge thick loose layer.展开更多
Significant progress has been made in the exploration and development of unconventional gas resources in China since the beginning of the 21st century.With a rapid increase in yield,the exploration and development of ...Significant progress has been made in the exploration and development of unconventional gas resources in China since the beginning of the 21st century.With a rapid increase in yield,the exploration and development of shale gas have been upgraded to a level of national strategy.Logging is one of the core technologies in gas exploration and development.However,logging technologies face the challenges of complex geological conditions and well casing environment,high temperature,high pressure,and strong heterogeneity.Despite the rich experience accumulated,unified understanding and implementation specifications are yet to be established for shale gas well logging.Given the analysis and comparison of the effectiveness and adaptability of logging technologies at different stages of shale gas exploration and development for the Sichuan Basin,this study optimizes the log suite to meet the demand for highefficiency exploration and development of shale gas.According to the adaptability analysis of shale gas log suite,the mandatory logging items of exploratory wells should include caliper log(CAL),natural gamma ray spectrometry(NGS)log,spontaneous potential(SP)log,directional survey,borehole compensated sonic log,litho-density log(LDL),compensated neutron log(CNL),dual laterologmicrospherically focused log/dual induction-laterolog log/array induction log,temperature log,elemental capture spectroscopy(ECS)log,formation microimager(FMI)log,and array sonic log.The log suite of appraisal wells is almost the same as that for exploratory wells,excluding the ECS log and microresistivity scanning imaging.Meanwhile,for the logging of horizontal/highly-deviated holes,the log suite of vertical wells should be referred to according to specific well conditions.展开更多
Efficient recycling technology for the rapid growth of spent lithium-ion batteries(LIBs)is essential to tackle the resources and environmental crisis.Hydrometallurgical approach has attracted extensive research due to...Efficient recycling technology for the rapid growth of spent lithium-ion batteries(LIBs)is essential to tackle the resources and environmental crisis.Hydrometallurgical approach has attracted extensive research due to its potential to reduce the consumption of energy and threat to the environment.However,the simultaneous realization of green,efficient and closed-loop recycling is still challenging.Herein,we report a closed-loop and highly efficient approach to recycle lithium cobalt oxide from spent LIBs based on a choline chloride:oxalic acid(ChCl:OA)type deep eutectic solvent(DES).An ultrafast leaching process is observed at 180°C for 10 s with no observable residues.The energy barrier during leaching is calculated to be 113.9 kJ/mol.Noteworthy,the solubility of cobalt ions can be reversibly tuned by simply adding/evaporating deionized water,thus avoiding the addition of precipitant and enabling the easy recovery of the leaching solvent for realizing a closed-loop recycling process.The simultaneous realization of high efficiency,green and closed-loop process is expected to push the DES into practical application for recycling the electrodes of LIBs.展开更多
The patial interpolation of borehole data is an important means of stratigraphic structure to construct a three-dimensional model of coal strata,and the reasonable selection of an effective spatial interpolation metho...The patial interpolation of borehole data is an important means of stratigraphic structure to construct a three-dimensional model of coal strata,and the reasonable selection of an effective spatial interpolation method will directly affect the accuracy of three-dimensional modeling of the strata.To select an effective spatial interpolation method and improve the accuracy of 3D modeling of formations,four interpolation methods(the inverse distance weight interpolation algorithm,the local polynomial interpolation algorithm,the radial basis neural network interpolation algorithm and the kriging interpolation algorithm)were compared and analyzed.In particular,the methods of interpolation algorithm,interpolation surface,sample test error,and cross-validation error were used.The experiment of 13-1 seam coal in the Huainan mining area showed the spatial surface interpolation effect of the radial basis neural network interpolation algorithm(RBF)compared with the inverse distance weight interpolation algorithm(IDW),local polynomial interpolation algorithm(LPI)and kriging algorithm.The three interpolation methods have higher accuracy and are more suitable for surface interpolation of coal seams,which is of great significance for improving the accuracy of subsequent 3D modeling of coal seams.展开更多
The Mufushan massif, as continental intra-plate magmatites located in the Jiangnan-Xuefeng orogenic belt of the South China. The Mufushan massif constitutes the largest Mesozoic intrusive complex, intruded the Mesopro...The Mufushan massif, as continental intra-plate magmatites located in the Jiangnan-Xuefeng orogenic belt of the South China. The Mufushan massif constitutes the largest Mesozoic intrusive complex, intruded the Mesoproterozoic Lengjiaxi Formation. Multiple geochronometric dating was used to reconstruct their evolution from emplacement to exhumation. The Mufushan granitoids were emplaced at ~150 Ma(U-Pb zircon) as post-orogenic magmatites contributing to Triassic crustal thickening. Onset of regional extension at ~128 Ma(40Ar/39Ar white mica and biotite) manifests a tectonic regime switch. Intense exhumation prior to ~55 Ma was followed by slow denudation and peneplanation for the next 37 Ma(~55–18 Ma). Accelerated cooling since ~18 Ma may have been caused by a far-field effect of the collision between IndiaAsia Plate or the Pacific-Plate subduction. Through a multi-geochronometric approach, this study provides a new comprehensive model for the cause of the intra-plate magmatism formation in the South China, and also established a reliable geochronological framework of the post-orogenic tectonic evolutions of the Jiangnan-Xuefeng orogenic belt.展开更多
Implant-associated infections are generally difficult to cure owing to the bacterial antibiotic resistance which is attributed to the widespread usage of antibiotics.Given the global threat and increasing influence of...Implant-associated infections are generally difficult to cure owing to the bacterial antibiotic resistance which is attributed to the widespread usage of antibiotics.Given the global threat and increasing influence of antibiotic resistance,there is an urgent demand to explore novel antibacterial strategies other than using antibiotics.Recently,using a certain surface topography to provide a more persistent antibacterial solution attracts more and more attention.However,the clinical application of biomimetic nano-pillar array is not satisfactory,mainly because its antibacterial ability against Gram-positive strain is not good enough.Thus,the pillar array should be equipped with other antibacterial agents to fulfill the bacteriostatic and bactericidal requirements of clinical application.Here,we designed a novel model substrate which was a combination of periodic micro/nano-pillar array and TiO2 for basically understanding the topographical bacteriostatic effects of periodic micro/nano-pillar array and the photocatalytic bactericidal activity of TiO2.Such innovation may potentially exert the synergistic effects by integrating the persistent topographical antibacterial activity and the non-invasive X-ray induced photocatalytic antibacterial property of TiO2 to combat against antibiotic-resistant implant-associated infections.First,to separately verify the topographical antibacterial activity of TiO2 periodic micro/nano-pillar array,we systematically investigated its effects on bacterial adhesion,growth,proliferation,and viability in the dark without involving the photocatalysis of TiO2.The pillar array with sub-micron motif size can significantly inhibit the adhesion,growth,and proliferation of Staphylococcus aureus(S.aureus)and Escherichia coli(E.coli).Such antibacterial ability is mainly attributed to a spatial confinement size-effect and limited contact area availability generated by the special topography of pillar array.Moreover,the pillar array is not lethal to S.aureus and E.coli in 24 h.Then,the X-ray induced photocatalytic antibacterial property of TiO2 periodic micro/nano-pillar array in vitro and in vivo will be systematically studied in a future work.This study could shed light on the direction of surface topography design for future medical implants to combat against antibiotic-resistant implant-associated infections without using antibiotics.展开更多
Biomedical implants have revolutionised medicine,while they also increase the risk of implant-associatedinfection which is one of the most frequent and severe complications accpmpanied by the application of biomateria...Biomedical implants have revolutionised medicine,while they also increase the risk of implant-associatedinfection which is one of the most frequent and severe complications accpmpanied by the application of biomaterials.Since the widespread usage of antibiotics drives the emergence of multidrug-resistant strains,the orthopaedic implantinfections are usually hard to treat due to the antibiotic resistance,tolerance and/or persistence of pathogens.Giventhe growing impact of multidrug resistance,an urgent need has been triggered to develop new types of antimicrobialstrategy other than using antibiotics.In this review,the authors highlight the recent progress on antimicrobialbiomaterials with non-antibiotic strategies including chemical strategy,physical strategy,and synergetic strategy.The antimicrobial mechanisms of many kinds of non-antibiotic antimicrobial biomaterials are still not fully understood.Researchers gradually found that welcoming microbial cellular adhesion to a lethal surface was a more effectivesolution than targeting microbial cellular repulsion when designing antimicrobial surfaces.Moreover,there is a populartendency to make the antimicrobial biomaterials not only kill pathogenic microbes but also facilitate the adhesion andgrowth of the healthy cell,which means that the next generation biomaterials should possess dual functions ofpreventing microbial infection together with promoting tissue regeneration simultaneously for biomedical applications.展开更多
Refractory metal niobium(Nb) incorporated with a small amount of silver(Ag),the resulting Nb-Ag twophase alloys,were fabricated by mechanical alloying and spark plasma sintering.The microstructure,mechanical propertie...Refractory metal niobium(Nb) incorporated with a small amount of silver(Ag),the resulting Nb-Ag twophase alloys,were fabricated by mechanical alloying and spark plasma sintering.The microstructure,mechanical properties,wear resistance,corrosion behavior,in vitro and in vivo antibacterial properties and biocompatibility of the Nb-Ag alloys were systematically investigated.The results show that the mechanical properties,wear resistance,corrosion resistance and antibacterial ability were significantly enhanced after addition of 5 at.% Ag.The fabricated Nb-5 at.% Ag alloy demonstrates high yield strength of up to ~1486 MPa and fracture strain of ~35 %.The precipitated Ag particles could reduce friction and wear.The enhanced corrosion resistance was attributed to the higher relative density of the sintered alloys and the formation of a stable and dense passive film of niobium and silver oxides.In vitro and in vivo evaluations show that the Nb-5 at.% Ag alloy also has strong antibacterial activity and good biocompatibility and osteointegration ability.These results demonstrate great potential of the nanostructured Nb-Ag alloys for dental and orthopedic implants.展开更多
Pluripotent stem cells hold tremendous promise for regenerative medicine.The mechanisms underlying the acquisition and loss of pluripotency have been revealed at multiple levels.Subcellular mechanisms such as metaboli...Pluripotent stem cells hold tremendous promise for regenerative medicine.The mechanisms underlying the acquisition and loss of pluripotency have been revealed at multiple levels.Subcellular mechanisms such as metabolic and organelle remodeling are emerging as critical for pluripotent cell fate transitions.Understanding the rules and roles of organelle remodeling will not only provide important insights into pluripotency regulation,but also help improving application in regenerative medicine.In this review,we summarize recent discoveries in organelle remodeling during the acquisition and loss of pluripotency and discuss how membrane lipids orchestrate organelle remodeling and drive nuclear gene expression.展开更多
基金supported by the National Natural Science Foundation of China (52262030)the Natural Science Foundation of Guizhou Science and Technology Department (QKHJC-ZK[2021]YB257)。
文摘Supercapacitor is an efficient energy storage device,yet its wider application is still limited by self-discharge.Currently,various composite materials have been reported to have improved inhibition on self-discharge,while the evaluation of the synergistic effect in composite materials is challenging.Herein,pairs of intercalation type pseudocapacitive niobium oxides are pre-lithiated and coupled to construct conjugatedly configured supercapacitors,within which the cathode and anode experience identical reaction environment with single type of charge carrier,thus providing ideal platform to quantify the synergistic effect of composite materials on the self-discharge process.By using titanium dioxide as the stabilizer,we have compared how the modes of forming composite would influence the selfdischarge performance of the active composite materials with similar ratio of the constituent materials.Specifically,core@shell Nb_(2)O_(5)@TiO_(2) composite using TiO_(2) as the shell shows significantly higher synergy coefficient(μ=0.61,defined as the value that evaluates the synergistic effect between composite materials,and can be quantified using the overall performance of the composite,performance of individual component as well as the ratio of the component.) than other control group samples,which corresponds to the highest retained energy of 63% at 100 h.This work is expected to provide a general method for quantifying the synergistic effect and guide the design of composite materials with specific mode of forming the composite.
文摘According to the characteristic of huge thick loose layer in Huainan mining area, based on the measured data, the correlation between the relative parameters of coal pillar setting and the ratio of loose layer thickness to mining depth in Huainan mining area under the mining condition of huge thick loose layer was mainly studied by using regression analysis method, and corresponding mathematical models were established and analyzed. It makes a theoretical supplement for the the analysis and research of mining subsidence rules in Huainan mining area under the condition of huge thick loose layer.
文摘Significant progress has been made in the exploration and development of unconventional gas resources in China since the beginning of the 21st century.With a rapid increase in yield,the exploration and development of shale gas have been upgraded to a level of national strategy.Logging is one of the core technologies in gas exploration and development.However,logging technologies face the challenges of complex geological conditions and well casing environment,high temperature,high pressure,and strong heterogeneity.Despite the rich experience accumulated,unified understanding and implementation specifications are yet to be established for shale gas well logging.Given the analysis and comparison of the effectiveness and adaptability of logging technologies at different stages of shale gas exploration and development for the Sichuan Basin,this study optimizes the log suite to meet the demand for highefficiency exploration and development of shale gas.According to the adaptability analysis of shale gas log suite,the mandatory logging items of exploratory wells should include caliper log(CAL),natural gamma ray spectrometry(NGS)log,spontaneous potential(SP)log,directional survey,borehole compensated sonic log,litho-density log(LDL),compensated neutron log(CNL),dual laterologmicrospherically focused log/dual induction-laterolog log/array induction log,temperature log,elemental capture spectroscopy(ECS)log,formation microimager(FMI)log,and array sonic log.The log suite of appraisal wells is almost the same as that for exploratory wells,excluding the ECS log and microresistivity scanning imaging.Meanwhile,for the logging of horizontal/highly-deviated holes,the log suite of vertical wells should be referred to according to specific well conditions.
基金supported by the Talented Program of Guizhou University(702759203301)the Natural Science Foundation of Guizhou Science and Technology Department(QKHJC-ZK[2021]-YB257)。
文摘Efficient recycling technology for the rapid growth of spent lithium-ion batteries(LIBs)is essential to tackle the resources and environmental crisis.Hydrometallurgical approach has attracted extensive research due to its potential to reduce the consumption of energy and threat to the environment.However,the simultaneous realization of green,efficient and closed-loop recycling is still challenging.Herein,we report a closed-loop and highly efficient approach to recycle lithium cobalt oxide from spent LIBs based on a choline chloride:oxalic acid(ChCl:OA)type deep eutectic solvent(DES).An ultrafast leaching process is observed at 180°C for 10 s with no observable residues.The energy barrier during leaching is calculated to be 113.9 kJ/mol.Noteworthy,the solubility of cobalt ions can be reversibly tuned by simply adding/evaporating deionized water,thus avoiding the addition of precipitant and enabling the easy recovery of the leaching solvent for realizing a closed-loop recycling process.The simultaneous realization of high efficiency,green and closed-loop process is expected to push the DES into practical application for recycling the electrodes of LIBs.
文摘The patial interpolation of borehole data is an important means of stratigraphic structure to construct a three-dimensional model of coal strata,and the reasonable selection of an effective spatial interpolation method will directly affect the accuracy of three-dimensional modeling of the strata.To select an effective spatial interpolation method and improve the accuracy of 3D modeling of formations,four interpolation methods(the inverse distance weight interpolation algorithm,the local polynomial interpolation algorithm,the radial basis neural network interpolation algorithm and the kriging interpolation algorithm)were compared and analyzed.In particular,the methods of interpolation algorithm,interpolation surface,sample test error,and cross-validation error were used.The experiment of 13-1 seam coal in the Huainan mining area showed the spatial surface interpolation effect of the radial basis neural network interpolation algorithm(RBF)compared with the inverse distance weight interpolation algorithm(IDW),local polynomial interpolation algorithm(LPI)and kriging algorithm.The three interpolation methods have higher accuracy and are more suitable for surface interpolation of coal seams,which is of great significance for improving the accuracy of subsequent 3D modeling of coal seams.
基金the NSFC projects(Nos.41972152,41672140,41372140)the“Thirteenth Five-Year”Major National Science and Technology Programs(Nos.2017ZX05032-002-004,2016ZX05024-002-005)+2 种基金the Special Fund for Basic Scientific Research of Central Colleges,China University of Geosciences,Wuhan(No.CUGCJ1820)the“111”Program(No.B14031)the Natural Science Foundation of Hubei Province(No.2016CFA055)。
文摘The Mufushan massif, as continental intra-plate magmatites located in the Jiangnan-Xuefeng orogenic belt of the South China. The Mufushan massif constitutes the largest Mesozoic intrusive complex, intruded the Mesoproterozoic Lengjiaxi Formation. Multiple geochronometric dating was used to reconstruct their evolution from emplacement to exhumation. The Mufushan granitoids were emplaced at ~150 Ma(U-Pb zircon) as post-orogenic magmatites contributing to Triassic crustal thickening. Onset of regional extension at ~128 Ma(40Ar/39Ar white mica and biotite) manifests a tectonic regime switch. Intense exhumation prior to ~55 Ma was followed by slow denudation and peneplanation for the next 37 Ma(~55–18 Ma). Accelerated cooling since ~18 Ma may have been caused by a far-field effect of the collision between IndiaAsia Plate or the Pacific-Plate subduction. Through a multi-geochronometric approach, this study provides a new comprehensive model for the cause of the intra-plate magmatism formation in the South China, and also established a reliable geochronological framework of the post-orogenic tectonic evolutions of the Jiangnan-Xuefeng orogenic belt.
基金supported by the Natural Science Foundation of Tianjin(General Program,No.18JCYBJC19500)the Independent Innovation Fund of Tianjin University(No.2019XZS-0014)the Research Grants Council of Hong Kong(No.HKUST615408).
文摘Implant-associated infections are generally difficult to cure owing to the bacterial antibiotic resistance which is attributed to the widespread usage of antibiotics.Given the global threat and increasing influence of antibiotic resistance,there is an urgent demand to explore novel antibacterial strategies other than using antibiotics.Recently,using a certain surface topography to provide a more persistent antibacterial solution attracts more and more attention.However,the clinical application of biomimetic nano-pillar array is not satisfactory,mainly because its antibacterial ability against Gram-positive strain is not good enough.Thus,the pillar array should be equipped with other antibacterial agents to fulfill the bacteriostatic and bactericidal requirements of clinical application.Here,we designed a novel model substrate which was a combination of periodic micro/nano-pillar array and TiO2 for basically understanding the topographical bacteriostatic effects of periodic micro/nano-pillar array and the photocatalytic bactericidal activity of TiO2.Such innovation may potentially exert the synergistic effects by integrating the persistent topographical antibacterial activity and the non-invasive X-ray induced photocatalytic antibacterial property of TiO2 to combat against antibiotic-resistant implant-associated infections.First,to separately verify the topographical antibacterial activity of TiO2 periodic micro/nano-pillar array,we systematically investigated its effects on bacterial adhesion,growth,proliferation,and viability in the dark without involving the photocatalysis of TiO2.The pillar array with sub-micron motif size can significantly inhibit the adhesion,growth,and proliferation of Staphylococcus aureus(S.aureus)and Escherichia coli(E.coli).Such antibacterial ability is mainly attributed to a spatial confinement size-effect and limited contact area availability generated by the special topography of pillar array.Moreover,the pillar array is not lethal to S.aureus and E.coli in 24 h.Then,the X-ray induced photocatalytic antibacterial property of TiO2 periodic micro/nano-pillar array in vitro and in vivo will be systematically studied in a future work.This study could shed light on the direction of surface topography design for future medical implants to combat against antibiotic-resistant implant-associated infections without using antibiotics.
基金the Natural ScienceFoundation of Tianjin(General Program,No.18ICYBJC19500)the Independent Innovation Fund of Tianjin University(2019XZS-0014).
文摘Biomedical implants have revolutionised medicine,while they also increase the risk of implant-associatedinfection which is one of the most frequent and severe complications accpmpanied by the application of biomaterials.Since the widespread usage of antibiotics drives the emergence of multidrug-resistant strains,the orthopaedic implantinfections are usually hard to treat due to the antibiotic resistance,tolerance and/or persistence of pathogens.Giventhe growing impact of multidrug resistance,an urgent need has been triggered to develop new types of antimicrobialstrategy other than using antibiotics.In this review,the authors highlight the recent progress on antimicrobialbiomaterials with non-antibiotic strategies including chemical strategy,physical strategy,and synergetic strategy.The antimicrobial mechanisms of many kinds of non-antibiotic antimicrobial biomaterials are still not fully understood.Researchers gradually found that welcoming microbial cellular adhesion to a lethal surface was a more effectivesolution than targeting microbial cellular repulsion when designing antimicrobial surfaces.Moreover,there is a populartendency to make the antimicrobial biomaterials not only kill pathogenic microbes but also facilitate the adhesion andgrowth of the healthy cell,which means that the next generation biomaterials should possess dual functions ofpreventing microbial infection together with promoting tissue regeneration simultaneously for biomedical applications.
基金financially supported by the Natural Science Foundation of Guangdong(Grant No.2019A1515011755)the Fundamental Research Program of Shenzhen(Grant Nos.JCYJ20170412153039309 and JCYJ20170307110418960)the Natural Science Foundation of Tianjin(General Program,No.18JCYBJC19500),China。
文摘Refractory metal niobium(Nb) incorporated with a small amount of silver(Ag),the resulting Nb-Ag twophase alloys,were fabricated by mechanical alloying and spark plasma sintering.The microstructure,mechanical properties,wear resistance,corrosion behavior,in vitro and in vivo antibacterial properties and biocompatibility of the Nb-Ag alloys were systematically investigated.The results show that the mechanical properties,wear resistance,corrosion resistance and antibacterial ability were significantly enhanced after addition of 5 at.% Ag.The fabricated Nb-5 at.% Ag alloy demonstrates high yield strength of up to ~1486 MPa and fracture strain of ~35 %.The precipitated Ag particles could reduce friction and wear.The enhanced corrosion resistance was attributed to the higher relative density of the sintered alloys and the formation of a stable and dense passive film of niobium and silver oxides.In vitro and in vivo evaluations show that the Nb-5 at.% Ag alloy also has strong antibacterial activity and good biocompatibility and osteointegration ability.These results demonstrate great potential of the nanostructured Nb-Ag alloys for dental and orthopedic implants.
基金supported by the National Key Research and Development Program of China(2018YFA0107100)the National Natural Science Foundation of China(Grant Nos.31622037and 31631163001).
文摘Pluripotent stem cells hold tremendous promise for regenerative medicine.The mechanisms underlying the acquisition and loss of pluripotency have been revealed at multiple levels.Subcellular mechanisms such as metabolic and organelle remodeling are emerging as critical for pluripotent cell fate transitions.Understanding the rules and roles of organelle remodeling will not only provide important insights into pluripotency regulation,but also help improving application in regenerative medicine.In this review,we summarize recent discoveries in organelle remodeling during the acquisition and loss of pluripotency and discuss how membrane lipids orchestrate organelle remodeling and drive nuclear gene expression.
