Dear Editor,I write to present one case report of a patient suffered the panophthalmitis caused by non-metallic foreign body with no etiologic agent and recovered quickly by phacoemulsification and vitrectomy with sil...Dear Editor,I write to present one case report of a patient suffered the panophthalmitis caused by non-metallic foreign body with no etiologic agent and recovered quickly by phacoemulsification and vitrectomy with silicone oil tamponade.Ocular trauma remains a major cause of blindness, particularly in the working-age population.展开更多
OBJECTIVE: To develope a new enzyme immune assay (ELISA) for detection of M2 antibody specificfor primary biliary cirrhosis (PBC) by using a triple hybrid clone as antigen, which coexpresses the threeimmunodominant li...OBJECTIVE: To develope a new enzyme immune assay (ELISA) for detection of M2 antibody specificfor primary biliary cirrhosis (PBC) by using a triple hybrid clone as antigen, which coexpresses the threeimmunodominant lipoyl domains of PDC-E2, BCOADC-E2 and OGDC-E2 from human sources.METHODS: After expressing autoantigens of PBC in prokaryote by constructing recombinant expressiveplasmid successfully, the fusion protein was purified by affinity chromatography. The sera of 17 PBCpatients were examined. As controls, the sera of 167 non-PBC patients and the sera of 1225 normalcontrols aged under 28 were examined.RESULTS: None of the sera from the non-PBC patients or the normal controls was positive for anti-M2shown by the new ELISA. However, the positivity rate for anti-M2 in the PBC patients was 100%(17/17), as shown by the new ELISA.CONCLUSION: The detection system with a good sensitivity and specificity may be used as a powerfulmethod for the diagnosis of PBC.展开更多
Dear sir,I am Dr Zhi-Qing Chen,from the Department of Ophthalmology of the Second Affiliated Hospital of Zhejiang University in Hangzhou,Zhejiang Province,China.I write to present two cases of neovascular age-related ...Dear sir,I am Dr Zhi-Qing Chen,from the Department of Ophthalmology of the Second Affiliated Hospital of Zhejiang University in Hangzhou,Zhejiang Province,China.I write to present two cases of neovascular age-related macular degeneration(AMD)occurred retinal pigment epithelium(RPE)tears after different treatment.RPE tear is a rare complication of neovascular AMD,展开更多
Choroidal neovascularization(CNV)is an uncommon complication associated with a macular hole.In this case report of a rare condition,we present a pathologic myopia patient with a co-existent macular hole and choroidal ...Choroidal neovascularization(CNV)is an uncommon complication associated with a macular hole.In this case report of a rare condition,we present a pathologic myopia patient with a co-existent macular hole and choroidal neovascular membrane.The patient was treated with photodynamic therapy for CNV,and then vitreous surgery for the retinal detachment and macular hole.At the end of 4 years follow-up,her visual acuity was improved to 0.1 while the macular hole remained open.Optical coherence tomography is a useful inspection method of the diagnosis of CNV and macular hole.展开更多
Dear Editor,I am Dr.Zhi-Tao Su,from the Eye Center,Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China.I write to present a case of spontaneous resolution of a traumatic cataract resulted ...Dear Editor,I am Dr.Zhi-Tao Su,from the Eye Center,Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China.I write to present a case of spontaneous resolution of a traumatic cataract resulted in good visual rehabilitation after removal of a ferrous intravitreal foreign body(IVFB).展开更多
Dear Sir,I am Dr.Zhe Xu,from the Eye Center,Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China.We write to present a case of resolution of siderotic glaucoma after removal of a retained f...Dear Sir,I am Dr.Zhe Xu,from the Eye Center,Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China.We write to present a case of resolution of siderotic glaucoma after removal of a retained ferrous foreign body.This study has been performed in accordance with the Declaration of Helsinki and was approved by the Ethics Committee of the Second Affiliated Hospital.展开更多
I am Dr.Ke Yao,from Eye Center,the Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China.I write to present three cases with metastatic choroidal tumor using an ultra-wide-field scanning las...I am Dr.Ke Yao,from Eye Center,the Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China.I write to present three cases with metastatic choroidal tumor using an ultra-wide-field scanning laser ophthalmoscope.展开更多
Dear Editor,We present a case of choroidal metastasis(CM)masquerading as circumscribed choroidal hemangioma as initial manifestation of lung adenocarcinoma.The study procedures were in accordance with the Declaration ...Dear Editor,We present a case of choroidal metastasis(CM)masquerading as circumscribed choroidal hemangioma as initial manifestation of lung adenocarcinoma.The study procedures were in accordance with the Declaration of Helsinki and were approved by the Institutional Review Board of the Second Affiliated Hospital of Zhejiang University School of Medicine.Written informed consent was obtained from the patient.展开更多
基金Supported by Natural Science Foundation of China (No.81571819 No.81500766)the Natural Science Foundation of Zhejiang Province, China (No.LY14H120004)
文摘Dear Editor,I write to present one case report of a patient suffered the panophthalmitis caused by non-metallic foreign body with no etiologic agent and recovered quickly by phacoemulsification and vitrectomy with silicone oil tamponade.Ocular trauma remains a major cause of blindness, particularly in the working-age population.
基金This study was supported by the National Natural Science Fundation of China (No. 30080027,39570673).
文摘OBJECTIVE: To develope a new enzyme immune assay (ELISA) for detection of M2 antibody specificfor primary biliary cirrhosis (PBC) by using a triple hybrid clone as antigen, which coexpresses the threeimmunodominant lipoyl domains of PDC-E2, BCOADC-E2 and OGDC-E2 from human sources.METHODS: After expressing autoantigens of PBC in prokaryote by constructing recombinant expressiveplasmid successfully, the fusion protein was purified by affinity chromatography. The sera of 17 PBCpatients were examined. As controls, the sera of 167 non-PBC patients and the sera of 1225 normalcontrols aged under 28 were examined.RESULTS: None of the sera from the non-PBC patients or the normal controls was positive for anti-M2shown by the new ELISA. However, the positivity rate for anti-M2 in the PBC patients was 100%(17/17), as shown by the new ELISA.CONCLUSION: The detection system with a good sensitivity and specificity may be used as a powerfulmethod for the diagnosis of PBC.
基金Supported by the Natural Science Foundation of Zhejiang Province(No.LY 16H 120002)Zhejiang Province Medical Platform Program Grant(No.2013RCB008)
文摘Dear sir,I am Dr Zhi-Qing Chen,from the Department of Ophthalmology of the Second Affiliated Hospital of Zhejiang University in Hangzhou,Zhejiang Province,China.I write to present two cases of neovascular age-related macular degeneration(AMD)occurred retinal pigment epithelium(RPE)tears after different treatment.RPE tear is a rare complication of neovascular AMD,
基金Public Welfare Technology Project of Science Technology Department of Zhejiang Province,China(No.2012C23068)
文摘Choroidal neovascularization(CNV)is an uncommon complication associated with a macular hole.In this case report of a rare condition,we present a pathologic myopia patient with a co-existent macular hole and choroidal neovascular membrane.The patient was treated with photodynamic therapy for CNV,and then vitreous surgery for the retinal detachment and macular hole.At the end of 4 years follow-up,her visual acuity was improved to 0.1 while the macular hole remained open.Optical coherence tomography is a useful inspection method of the diagnosis of CNV and macular hole.
基金Supported by the National Natural Science Foundation of China(No.81800877)the Natural Science Foundation of Zhejiang Province(No.LY15H120001No.LQ17H120008)。
文摘Dear Editor,I am Dr.Zhi-Tao Su,from the Eye Center,Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China.I write to present a case of spontaneous resolution of a traumatic cataract resulted in good visual rehabilitation after removal of a ferrous intravitreal foreign body(IVFB).
基金Supported by the National Natural Science Foundation of China(No.81800877)the Natural Science Foundation of Zhejiang Province(No.LY15H120001,No.LQ17H120008)。
文摘Dear Sir,I am Dr.Zhe Xu,from the Eye Center,Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China.We write to present a case of resolution of siderotic glaucoma after removal of a retained ferrous foreign body.This study has been performed in accordance with the Declaration of Helsinki and was approved by the Ethics Committee of the Second Affiliated Hospital.
基金Supported by Zhejiang Natural Science Foundation Project of China (No.LY18H120001)
文摘I am Dr.Ke Yao,from Eye Center,the Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China.I write to present three cases with metastatic choroidal tumor using an ultra-wide-field scanning laser ophthalmoscope.
基金Supported by Medical Scientific Research Foundation of Zhejiang Province,China(No.201130184)。
文摘Dear Editor,We present a case of choroidal metastasis(CM)masquerading as circumscribed choroidal hemangioma as initial manifestation of lung adenocarcinoma.The study procedures were in accordance with the Declaration of Helsinki and were approved by the Institutional Review Board of the Second Affiliated Hospital of Zhejiang University School of Medicine.Written informed consent was obtained from the patient.
基金Project supported by the Qianjiang Talents Project of Zhejiang Province(No.2010R10067)the Zhejiang Key Innovation Team Project of China(No.2009R50039)the Zhejiang Key Laboratory Foundation of China(No.2011E10006)
