Background:The impacts of selective logging on ecosystem multifunctionality(EMF)remain largely unexplored.In this study,we analyzed the response of nine variables related to four ecosystem functions(i.e.nutrient cycli...Background:The impacts of selective logging on ecosystem multifunctionality(EMF)remain largely unexplored.In this study,we analyzed the response of nine variables related to four ecosystem functions(i.e.nutrient cycling,soil carbon stocks,decomposition,and wood production)to five selective logging intensities in a Pinus yunnanensisdominated forest.We included a control group with no harvest to evaluate the potential shifts in EMF of the P.yunnanensis forests.We also assessed the relationship between above-and belowground biodiversity and EMF under these different selective logging intensities.Additionally,we evaluated the effects of biotic and abiotic factors on EMF using a structural equation modeling(SEM)approach.Results:Individual ecosystem functions(EFs)all had a significant positive correlation with selective logging intensity.Different EFs showed different patterns with the increase of selective logging intensity.We found that EMF tended to increase with logging intensity,and that EMF significantly improved when the stand was harvested at least twice.Both functional diversity and soil moisture had a significant positive correlation with EMF,but soil fungal operational taxonomic units(OTUs)had a significant negative correlation with EMF.Based on SEM,we found that selective logging improved EMF mainly by increasing functional diversity.Conclusion:Our study demonstrates that selective logging is a good management technique from an EMF perspective,and thus provide us with potential guidelines to improve forest management in P.yunnanensis forests in this region.The functional diversity is maximized through reasonable selective logging measures,so as to enhance EMF.展开更多
Objective:The aim of our study was to comprehensively access current status of radiotherapy physicians' opinions in post-mastectomy radiotherapy(PMRT) for breast cancer in Guangdong province.Methods:From June 2007...Objective:The aim of our study was to comprehensively access current status of radiotherapy physicians' opinions in post-mastectomy radiotherapy(PMRT) for breast cancer in Guangdong province.Methods:From June 2007 to June 2008,questionnaires on the clinical value,sequencing with chemotherapy and endocrine therapy,indications and irradiated targets for PMRT were sent to physicians of all radiotherapy departments registering at Radiotherapy Professional Committee of Guangdong Anti-cancer Association.Results:There were 126 physicians joining this investigation.Proportions of physicians who accepted the views that PMRT could merely improve local control or can improve both local control and overall survival were 100% and 25.2%.The most common sequences of PMRT and chemotherapy or endocrine therapy were "sandwich" and sequential modes,performed 46.9% and 59.5% respectively.The median interval of surgery and PMRT was 8 weeks.Proportions of physicians who accepted T3-4 diseases,or four or more axillary lymph nodes metastasis,or T1-2 with 1-3 positive lymph nodes,or T1-2N0 with primary tumor located in the center or inner quadrant as the indications of PMRT were 97.6%,100%,46.8%,13.5%,respectively.Proportions of physicians who accepted chest wall,supraclavicular region,internal mammary chain or axilla as irradiated targets were 86.5%,100%,49.2% and 38.9% respectively.Conclusion:For Radiotherapy physicians of Guangdong Province,there is still lacking of consensus in the opinions of whether PMRT can improve survival,and optimal sequencing with chemotherapy or endocrine therapy,and how to make decision for patients with T1-2 with 1-3 positive lymph nodes,and rational irradiated targets,which requires advanced professional training for physicians and further prospective clinical trial evidences to guide clinical practice.展开更多
Systemic lupus erythematosus(SLE)is an autoimmune disease,characterized by the production of autoantibodies and the involvement of multi-systems.In order to explore its molecular mechanism,we,using bioinformatics anal...Systemic lupus erythematosus(SLE)is an autoimmune disease,characterized by the production of autoantibodies and the involvement of multi-systems.In order to explore its molecular mechanism,we,using bioinformatics analysis and wet lab experiments,identified two key genes in SLE patients.展开更多
In the past decade,ozone(O_(3))pollution has been continuously worsening in most developing countries.The accurate identification of the nonlinear relationship between O_(3) and its precursors is a prerequisite for fo...In the past decade,ozone(O_(3))pollution has been continuously worsening in most developing countries.The accurate identification of the nonlinear relationship between O_(3) and its precursors is a prerequisite for formulating effective O_(3) control measures.At present,precursor-based O_(3) isopleth diagrams are widely used to infer O_(3) control strategy at a particular location.However,there is frequently a large gap between the O_(3)-precursor nonlinearity delineated by the O_(3) isopleths and the emission source control measures to reduce O_(3) levels.Consequently,we developed an emission source-based O_(3) isopleth diagram that directly illustrates the O_(3) level changes in response to synergistic control on two types of emission sources using a validated numerical modeling system and the latest regional emission inventory.Isopleths can be further upgraded to isosurfaces when co-control on three types of emission sources is investigated.Using Guangzhou and Foshan as examples,we demonstrate that similar precursor-based O_(3) isopleths can be associated with significantly different emission source co-control strategies.In Guangzhou,controlling solvent use emissions was the most effective approach to reduce peak O_(3) levels.In Foshan,co-control of on-road mobile,solvent use,and fixed combustion sources with a ratio of 3:1:2 or 3:1:3 was best to effectively reduce the peak O_(3) levels below 145 ppbv.This study underscores the importance of using emission source-based O_(3) isopleths and isosurface diagrams to guide a precursor emission control strategy that can effectively reduce the peak O_(3) levels in a particular area.展开更多
A photocleavable low-molecular-weight hydrogelator (LMWG) was synthesized based on coumarin derivative.~1H NMR and UV spectroscopy study suggested that the gelator had good gelling ability, and the driving force for t...A photocleavable low-molecular-weight hydrogelator (LMWG) was synthesized based on coumarin derivative.~1H NMR and UV spectroscopy study suggested that the gelator had good gelling ability, and the driving force for the gelation were hydrogen bonding and π-π stacking. This molecular hydrogel exhibited satisfied photocleavage at C-N bond in 7-amino coumarin with the light irradiation (365 nm,77.5 mW/cm^2). The promising photo-triggered drug release of antineoplastics cytarabine hydrochloride has been obtained, due to the photocleavage motived gel-sol transition.展开更多
The natural frequencies, complex modes and critical speeds of an axially moving rectangular plate, which is partially immersed in a fluid and subjected to a pretension, are investigated. The effects of free surface wa...The natural frequencies, complex modes and critical speeds of an axially moving rectangular plate, which is partially immersed in a fluid and subjected to a pretension, are investigated. The effects of free surface waves, compressibility and viscidity of the fluid are neglected in the analysis. The subsection functions are used to describe the discontinuous characteristics of the system due to partial immersion. The classical thin plate theory is adopted to formulate the equations of motion of a vibrating plate. The velocity potential and Bernoulli＇s equation are used to describe the fluid pressure acting on the moving plate. The effect of fluid on the vibrations of the plate may be equivalent to the added mass on the plate. The effects of distance ratio, moving speed, immersed-depth ratio, boundary conditions, stiffness ratio and aspect ratio of the plate as well as the fluid-plate density ratios on the free vibrations of the moving plate-fluid system are investigated.展开更多
Moisture capacity of iron ore, defined as its ability to hold water, has been found to be attected by Its particle size and chemical composition. To explain this phenomenon, mathematical model was developed on the bas...Moisture capacity of iron ore, defined as its ability to hold water, has been found to be attected by Its particle size and chemical composition. To explain this phenomenon, mathematical model was developed on the basis of particle size, specific surface area, pore properties and contact angle between the iron ore and water. The specific surface area and the pore volume of iron ores were measured to validate the model, and parametric studies were carried out to investigate the effects of these factors, showing that particle size and surface area of the iron ore and thickness of the water film are the principal factors determining the moisture capacity. The model gave reasonable explanation of the phenomenon that moisture capacity increases with decreasing particle size. A correlation developed can well predict the moisture capacity of iron ores. Deviations between measurements and calculations were analyzed.展开更多
Host-guest supramolecular gels were developed via the self-assembly of inclusion complexes(ICs) ofβ-cyclodextrins/phenylboronic acid gelator(PBA).Salts and current were involved in the self-assembly to stabilize the ...Host-guest supramolecular gels were developed via the self-assembly of inclusion complexes(ICs) ofβ-cyclodextrins/phenylboronic acid gelator(PBA).Salts and current were involved in the self-assembly to stabilize the host-guest gels.The stability of the gels was greatly improved after salts were added.The stable time of gels was extended from 2.5 h to 120 h with the addition of NH_4 NO_3 at the concentration of 2.5×10^(-2) g/mL.The morphology of the gel was affected by the concentrations of NH_4NO_3.SEM images revealed that the gels were three-dimensional nanofibrous networks,the sizes of fibers decreased with decreasing NH_4NO_3 concentrations,which affected the stability of gels,further proved by the rheological properties of gels.More stable gels were obtained with current stimulation,the stable time of the gel was increased from 2.5 h to 55 h with current by adding NaBF_4.The current also exhibited significant influence on the aggregation as the voltage varied(0-500 mV) with a constant concentration of salts.The result showed the self-assembly process of host-guest gel could be well controlled via the addition of salts and current to desired morphology and stability.展开更多
Sodium metal is a promising anode for sodium batteries due to its high theoretical capacity and low cost.However,the serious Na dendrite growth and low Coulombic efficiency,especially at high current densities/cycling...Sodium metal is a promising anode for sodium batteries due to its high theoretical capacity and low cost.However,the serious Na dendrite growth and low Coulombic efficiency,especially at high current densities/cycling capacities,severely limit the application of sodium metal anodes.Herein,trifluoromethylfullerene,C_(60)(CF_(3))_(6),is designed as an electrolyte additive to enable the high-rate cycling of sodium metal anodes with high Coulombic efficiency.The CF3 groups contribute to the formation of stable NaF-rich solid electrolyte interface layer,while C_(60)cages induce the uniform distribution of sodium ions and promote the formation of smooth and compact morphology.Thus,Na||Cu cell with C_(60)(CF_(3))_(6)can be cycled at 2 mA·cm^(−2)and 10 mAh·cm^(−2)over 180 cycles with an average Coulombic efficiency of 99.9%,and Na||Na cell can be cycled at 10 mA·cm^(−2)over 600 cycles.Furthermore,Na||NaV2(PO_(4))_(3)@C full cell exhibits high capacity retention of 84%over 2,000 cycles at 20 C(~3 mA·cm^(−2)).展开更多
A novel fluorescence chemosensor 1 based on （R）-binaphthyl-salen can exhibit highly sensitive and selective recognition responses toward Cu^2＋ by ＂turn-off＂ fluorescence quench type in THF/H20, and Zn^2＋ by ＂tu...A novel fluorescence chemosensor 1 based on （R）-binaphthyl-salen can exhibit highly sensitive and selective recognition responses toward Cu^2＋ by ＂turn-off＂ fluorescence quench type in THF/H20, and Zn^2＋ by ＂turn-on＂ fluorescence enhancement type in CHC13/CH3CN, respectively, suggesting that solvents can dramatically affect the responsive properties of salen-based chemosensor. In addition, Cu^2＋ can lead to the most pronounced changes of CD spectra without the influence of solvents, which indicates this kind chemosensor can also be used as a sole Cu^2＋ probe based on CD spectra.展开更多
To the Editor:The coronavirus disease2019(COVID-19)outbreak developedinto a pandemic.Patientsundergoing hemodialysis(HD)are more susceptible to COVID-19,and isolating patients undergoing HD after exposure are extremel...To the Editor:The coronavirus disease2019(COVID-19)outbreak developedinto a pandemic.Patientsundergoing hemodialysis(HD)are more susceptible to COVID-19,and isolating patients undergoing HD after exposure are extremely challenging since they frequently travel between their homes and dialysis centers,during which they share a hall for dialysis sessions that may last for hours.We successfully quarantined one infected HD patient and other potentially exposed patients.This experience might serve as an important reference for dialysis centers or for people in similar situations across the country to reduce the spread of COVID-19.展开更多
Prostate cancer is a clinically heterogeneous disease and remains the most common non-skin malignancy in men worldwide(Abate-Shen and Shen,2000;Litwin and Tan,2017),which is often diagnosed through screening with digi...Prostate cancer is a clinically heterogeneous disease and remains the most common non-skin malignancy in men worldwide(Abate-Shen and Shen,2000;Litwin and Tan,2017),which is often diagnosed through screening with digital rectal examinations and quantitation of serum levels of prostate-specific antigen(PSA).At the morphological aspect,the Gleason scoring system is regarded as the most reliable and predictive histo-logical grading system(Welch and Albertsen,2009;Heidenreich et al.,2011).展开更多
Type A aortic aneurysm and dissection secondary to bicuspid aortic valve(BAV)with untreated coarctation of the aorta(CoA)in adults is a rare finding because there are almost no“abnormalities”in these patients’medic...Type A aortic aneurysm and dissection secondary to bicuspid aortic valve(BAV)with untreated coarctation of the aorta(CoA)in adults is a rare finding because there are almost no“abnormalities”in these patients’medical histories.Here,we report on a 47-year-old man with unexplained weakness followed by unconsciousness.He was diagnosed with cardiogenic shock and underwent venoarterial extracorporeal membrane oxygenation(VA-ECMO).BAV,ascending aortic aneurysm and dissection(based on bedside echocardiography)and concomitant CoA(based on computed tomography angiography)were confirmed.The patient then underwent emergency surgery including aortic root replacement with a composite mechanical valve conduit,additional ascending-to-descending aortic bypass,and coronary artery bypass grafting with a saphenous vein graft to the right coronary artery.After treatment,he recovered uneventfully.Thus,here we present a case involving a patient in a critical condition with ascending aortic aneurysm and dissection secondary to complex congenital heart defects,who was successfully treated with composite surgical procedures combined with life-saving VA-ECMO.展开更多
The feasibility and safety of intracardiac echocardiography(ICE)-guided catheter ablation for atrial fibrillation(AF)using a minimal/zero-fluoroscopy approach have recently been reported.This approach helps to reduce ...The feasibility and safety of intracardiac echocardiography(ICE)-guided catheter ablation for atrial fibrillation(AF)using a minimal/zero-fluoroscopy approach have recently been reported.This approach helps to reduce ionizing radiation exposure and orthopedic complications resulting from using lead aprons.The objectives of this planned prospective,multicenter randomized controlled trial(RCT)(paroxysmal AF(PAF)-ICE trial;ChiCTR2000033624)are to evaluate the efficacy and safety of ICE-guided minimal-fluoroscopy ablation in patients with PAF and the impact on occupational hazards among lab staff.Patients will be randomized in a 1:1 ratio to 2 groups:minimal fluoroscopy group(n=216)and traditional approach group(n=216).In the minimal fluoroscopy group,an ICE catheter will be used for geometry/anatomic construction,transseptal puncture,catheter tracking,and effusion monitoring.Pulmonary vein isolation(PVI)will be performed using an open-irrigated radiofrequency SmartTouch Surround Flow or SmartTouch catheter(Biosense Webster,Diamond Bar,California,USA),and confirmed by a multipolar Lasso or PentaRay catheter(Biosense Webster).In the traditional approach group,an ICE catheter will not be used.Transseptal puncture will be performed under fluoroscopic guidance,with all geometries constructed by mapping the catheters.The primary efficacy endpoint is freedom from AF recurrence(without antiarrhythmic medications)at 12months after ablation.Other endpoints include duration of lead apron use,measures of intra-procedural efficiency,and peri-procedural complications.This RCT will evaluate the efficacy and safety of ICE-guided minimal-fluoroscopy ablation in patients with PAF,also evaluate the benefits to lab staff(regarding reducing occupational hazards)related to this“minimal/zero-fluoroscopy”and“leadless”mode.展开更多
基金the Fundamental Research Funds of CAF(CAFYBB2017ZX002)Yunnan Basic Research Program(2019FB058).
文摘Background:The impacts of selective logging on ecosystem multifunctionality(EMF)remain largely unexplored.In this study,we analyzed the response of nine variables related to four ecosystem functions(i.e.nutrient cycling,soil carbon stocks,decomposition,and wood production)to five selective logging intensities in a Pinus yunnanensisdominated forest.We included a control group with no harvest to evaluate the potential shifts in EMF of the P.yunnanensis forests.We also assessed the relationship between above-and belowground biodiversity and EMF under these different selective logging intensities.Additionally,we evaluated the effects of biotic and abiotic factors on EMF using a structural equation modeling(SEM)approach.Results:Individual ecosystem functions(EFs)all had a significant positive correlation with selective logging intensity.Different EFs showed different patterns with the increase of selective logging intensity.We found that EMF tended to increase with logging intensity,and that EMF significantly improved when the stand was harvested at least twice.Both functional diversity and soil moisture had a significant positive correlation with EMF,but soil fungal operational taxonomic units(OTUs)had a significant negative correlation with EMF.Based on SEM,we found that selective logging improved EMF mainly by increasing functional diversity.Conclusion:Our study demonstrates that selective logging is a good management technique from an EMF perspective,and thus provide us with potential guidelines to improve forest management in P.yunnanensis forests in this region.The functional diversity is maximized through reasonable selective logging measures,so as to enhance EMF.
文摘Objective:The aim of our study was to comprehensively access current status of radiotherapy physicians' opinions in post-mastectomy radiotherapy(PMRT) for breast cancer in Guangdong province.Methods:From June 2007 to June 2008,questionnaires on the clinical value,sequencing with chemotherapy and endocrine therapy,indications and irradiated targets for PMRT were sent to physicians of all radiotherapy departments registering at Radiotherapy Professional Committee of Guangdong Anti-cancer Association.Results:There were 126 physicians joining this investigation.Proportions of physicians who accepted the views that PMRT could merely improve local control or can improve both local control and overall survival were 100% and 25.2%.The most common sequences of PMRT and chemotherapy or endocrine therapy were "sandwich" and sequential modes,performed 46.9% and 59.5% respectively.The median interval of surgery and PMRT was 8 weeks.Proportions of physicians who accepted T3-4 diseases,or four or more axillary lymph nodes metastasis,or T1-2 with 1-3 positive lymph nodes,or T1-2N0 with primary tumor located in the center or inner quadrant as the indications of PMRT were 97.6%,100%,46.8%,13.5%,respectively.Proportions of physicians who accepted chest wall,supraclavicular region,internal mammary chain or axilla as irradiated targets were 86.5%,100%,49.2% and 38.9% respectively.Conclusion:For Radiotherapy physicians of Guangdong Province,there is still lacking of consensus in the opinions of whether PMRT can improve survival,and optimal sequencing with chemotherapy or endocrine therapy,and how to make decision for patients with T1-2 with 1-3 positive lymph nodes,and rational irradiated targets,which requires advanced professional training for physicians and further prospective clinical trial evidences to guide clinical practice.
基金supported by the National Natural Science Foundation of China(No.81802504,81872207)Sichuan Science and Technology Bureau,China(No.2019YFS0439,2020JDJQ0067,2020JDRC0118,2021YJ0564,and 2022YFH0005)+1 种基金the Science and Technology Innovation Project of Chengdu,China(No.2021-YF05-00225-SN)a Sichuan Medical Association grant(China)(No.Q19037).
文摘Systemic lupus erythematosus(SLE)is an autoimmune disease,characterized by the production of autoantibodies and the involvement of multi-systems.In order to explore its molecular mechanism,we,using bioinformatics analysis and wet lab experiments,identified two key genes in SLE patients.
基金supported by the National Natural Science Foundation of China(No.91644221)the National Key Re-search and Development Program(2016YFC0202201).
文摘In the past decade,ozone(O_(3))pollution has been continuously worsening in most developing countries.The accurate identification of the nonlinear relationship between O_(3) and its precursors is a prerequisite for formulating effective O_(3) control measures.At present,precursor-based O_(3) isopleth diagrams are widely used to infer O_(3) control strategy at a particular location.However,there is frequently a large gap between the O_(3)-precursor nonlinearity delineated by the O_(3) isopleths and the emission source control measures to reduce O_(3) levels.Consequently,we developed an emission source-based O_(3) isopleth diagram that directly illustrates the O_(3) level changes in response to synergistic control on two types of emission sources using a validated numerical modeling system and the latest regional emission inventory.Isopleths can be further upgraded to isosurfaces when co-control on three types of emission sources is investigated.Using Guangzhou and Foshan as examples,we demonstrate that similar precursor-based O_(3) isopleths can be associated with significantly different emission source co-control strategies.In Guangzhou,controlling solvent use emissions was the most effective approach to reduce peak O_(3) levels.In Foshan,co-control of on-road mobile,solvent use,and fixed combustion sources with a ratio of 3:1:2 or 3:1:3 was best to effectively reduce the peak O_(3) levels below 145 ppbv.This study underscores the importance of using emission source-based O_(3) isopleths and isosurface diagrams to guide a precursor emission control strategy that can effectively reduce the peak O_(3) levels in a particular area.
基金financial support from the National Natural Science Foundation of China (Nos. 21672164, 21372177)
文摘A photocleavable low-molecular-weight hydrogelator (LMWG) was synthesized based on coumarin derivative.~1H NMR and UV spectroscopy study suggested that the gelator had good gelling ability, and the driving force for the gelation were hydrogen bonding and π-π stacking. This molecular hydrogel exhibited satisfied photocleavage at C-N bond in 7-amino coumarin with the light irradiation (365 nm,77.5 mW/cm^2). The promising photo-triggered drug release of antineoplastics cytarabine hydrochloride has been obtained, due to the photocleavage motived gel-sol transition.
基金Project supported by the National Natural Science Foundation of China(Nos.11302046 and 11172063)
文摘The natural frequencies, complex modes and critical speeds of an axially moving rectangular plate, which is partially immersed in a fluid and subjected to a pretension, are investigated. The effects of free surface waves, compressibility and viscidity of the fluid are neglected in the analysis. The subsection functions are used to describe the discontinuous characteristics of the system due to partial immersion. The classical thin plate theory is adopted to formulate the equations of motion of a vibrating plate. The velocity potential and Bernoulli＇s equation are used to describe the fluid pressure acting on the moving plate. The effect of fluid on the vibrations of the plate may be equivalent to the added mass on the plate. The effects of distance ratio, moving speed, immersed-depth ratio, boundary conditions, stiffness ratio and aspect ratio of the plate as well as the fluid-plate density ratios on the free vibrations of the moving plate-fluid system are investigated.
基金the Fundamental Research Funds for the Central Universities (Grant No. CDJRC10130009)National Natural Science Foundation of China (Grant No.51104192)
文摘Moisture capacity of iron ore, defined as its ability to hold water, has been found to be attected by Its particle size and chemical composition. To explain this phenomenon, mathematical model was developed on the basis of particle size, specific surface area, pore properties and contact angle between the iron ore and water. The specific surface area and the pore volume of iron ores were measured to validate the model, and parametric studies were carried out to investigate the effects of these factors, showing that particle size and surface area of the iron ore and thickness of the water film are the principal factors determining the moisture capacity. The model gave reasonable explanation of the phenomenon that moisture capacity increases with decreasing particle size. A correlation developed can well predict the moisture capacity of iron ores. Deviations between measurements and calculations were analyzed.
基金financial support from the National Natural Science Foundation of China(No.21672164)Wenzhou Science and Technology Bureau(No.Y20170162)Graduate Innovation Fund of Wenzhou University(No.3162018031)。
文摘Host-guest supramolecular gels were developed via the self-assembly of inclusion complexes(ICs) ofβ-cyclodextrins/phenylboronic acid gelator(PBA).Salts and current were involved in the self-assembly to stabilize the host-guest gels.The stability of the gels was greatly improved after salts were added.The stable time of gels was extended from 2.5 h to 120 h with the addition of NH_4 NO_3 at the concentration of 2.5×10^(-2) g/mL.The morphology of the gel was affected by the concentrations of NH_4NO_3.SEM images revealed that the gels were three-dimensional nanofibrous networks,the sizes of fibers decreased with decreasing NH_4NO_3 concentrations,which affected the stability of gels,further proved by the rheological properties of gels.More stable gels were obtained with current stimulation,the stable time of the gel was increased from 2.5 h to 55 h with current by adding NaBF_4.The current also exhibited significant influence on the aggregation as the voltage varied(0-500 mV) with a constant concentration of salts.The result showed the self-assembly process of host-guest gel could be well controlled via the addition of salts and current to desired morphology and stability.
基金the National Science Foundation of China(Nos.21925104,51672093,51821005,U1966214,51902116,and 21975087)。
文摘Sodium metal is a promising anode for sodium batteries due to its high theoretical capacity and low cost.However,the serious Na dendrite growth and low Coulombic efficiency,especially at high current densities/cycling capacities,severely limit the application of sodium metal anodes.Herein,trifluoromethylfullerene,C_(60)(CF_(3))_(6),is designed as an electrolyte additive to enable the high-rate cycling of sodium metal anodes with high Coulombic efficiency.The CF3 groups contribute to the formation of stable NaF-rich solid electrolyte interface layer,while C_(60)cages induce the uniform distribution of sodium ions and promote the formation of smooth and compact morphology.Thus,Na||Cu cell with C_(60)(CF_(3))_(6)can be cycled at 2 mA·cm^(−2)and 10 mAh·cm^(−2)over 180 cycles with an average Coulombic efficiency of 99.9%,and Na||Na cell can be cycled at 10 mA·cm^(−2)over 600 cycles.Furthermore,Na||NaV2(PO_(4))_(3)@C full cell exhibits high capacity retention of 84%over 2,000 cycles at 20 C(~3 mA·cm^(−2)).
基金the National Natural Science Foundation of China，National Basic Research Program of China，Zhejiang Provincial Natural Science Foundation，the Bureau of Science and Technology of Wenzhou
文摘A novel fluorescence chemosensor 1 based on （R）-binaphthyl-salen can exhibit highly sensitive and selective recognition responses toward Cu^2＋ by ＂turn-off＂ fluorescence quench type in THF/H20, and Zn^2＋ by ＂turn-on＂ fluorescence enhancement type in CHC13/CH3CN, respectively, suggesting that solvents can dramatically affect the responsive properties of salen-based chemosensor. In addition, Cu^2＋ can lead to the most pronounced changes of CD spectra without the influence of solvents, which indicates this kind chemosensor can also be used as a sole Cu^2＋ probe based on CD spectra.
基金Peking University Special Fund for COVID-19 Prevention and Control(No.PKU2020PKYZX001)。
文摘To the Editor:The coronavirus disease2019(COVID-19)outbreak developedinto a pandemic.Patientsundergoing hemodialysis(HD)are more susceptible to COVID-19,and isolating patients undergoing HD after exposure are extremely challenging since they frequently travel between their homes and dialysis centers,during which they share a hall for dialysis sessions that may last for hours.We successfully quarantined one infected HD patient and other potentially exposed patients.This experience might serve as an important reference for dialysis centers or for people in similar situations across the country to reduce the spread of COVID-19.
基金This research was supported by the Center for Health Statistics and Information,National Health Commission of China(2127000141).
文摘Prostate cancer is a clinically heterogeneous disease and remains the most common non-skin malignancy in men worldwide(Abate-Shen and Shen,2000;Litwin and Tan,2017),which is often diagnosed through screening with digital rectal examinations and quantitation of serum levels of prostate-specific antigen(PSA).At the morphological aspect,the Gleason scoring system is regarded as the most reliable and predictive histo-logical grading system(Welch and Albertsen,2009;Heidenreich et al.,2011).
基金supported by the National Natural Science and Technology Foundation of China(81800274 to QJ)Sichuan Science and Technology Program(2021JDJQ0041 to QJ)Grant for Clinical Translation Research of Sichuan Provincial People’s Hospital(2017LY07 to QJ).
文摘Type A aortic aneurysm and dissection secondary to bicuspid aortic valve(BAV)with untreated coarctation of the aorta(CoA)in adults is a rare finding because there are almost no“abnormalities”in these patients’medical histories.Here,we report on a 47-year-old man with unexplained weakness followed by unconsciousness.He was diagnosed with cardiogenic shock and underwent venoarterial extracorporeal membrane oxygenation(VA-ECMO).BAV,ascending aortic aneurysm and dissection(based on bedside echocardiography)and concomitant CoA(based on computed tomography angiography)were confirmed.The patient then underwent emergency surgery including aortic root replacement with a composite mechanical valve conduit,additional ascending-to-descending aortic bypass,and coronary artery bypass grafting with a saphenous vein graft to the right coronary artery.After treatment,he recovered uneventfully.Thus,here we present a case involving a patient in a critical condition with ascending aortic aneurysm and dissection secondary to complex congenital heart defects,who was successfully treated with composite surgical procedures combined with life-saving VA-ECMO.
基金supported by the Investigator-Initiated Study Program of Biosense Webster,Inc.(Diamond Bar,California,USA).
文摘The feasibility and safety of intracardiac echocardiography(ICE)-guided catheter ablation for atrial fibrillation(AF)using a minimal/zero-fluoroscopy approach have recently been reported.This approach helps to reduce ionizing radiation exposure and orthopedic complications resulting from using lead aprons.The objectives of this planned prospective,multicenter randomized controlled trial(RCT)(paroxysmal AF(PAF)-ICE trial;ChiCTR2000033624)are to evaluate the efficacy and safety of ICE-guided minimal-fluoroscopy ablation in patients with PAF and the impact on occupational hazards among lab staff.Patients will be randomized in a 1:1 ratio to 2 groups:minimal fluoroscopy group(n=216)and traditional approach group(n=216).In the minimal fluoroscopy group,an ICE catheter will be used for geometry/anatomic construction,transseptal puncture,catheter tracking,and effusion monitoring.Pulmonary vein isolation(PVI)will be performed using an open-irrigated radiofrequency SmartTouch Surround Flow or SmartTouch catheter(Biosense Webster,Diamond Bar,California,USA),and confirmed by a multipolar Lasso or PentaRay catheter(Biosense Webster).In the traditional approach group,an ICE catheter will not be used.Transseptal puncture will be performed under fluoroscopic guidance,with all geometries constructed by mapping the catheters.The primary efficacy endpoint is freedom from AF recurrence(without antiarrhythmic medications)at 12months after ablation.Other endpoints include duration of lead apron use,measures of intra-procedural efficiency,and peri-procedural complications.This RCT will evaluate the efficacy and safety of ICE-guided minimal-fluoroscopy ablation in patients with PAF,also evaluate the benefits to lab staff(regarding reducing occupational hazards)related to this“minimal/zero-fluoroscopy”and“leadless”mode.
