The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the...The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the on-orbit performance of our newly developed Sc/Si multi-layer reflecting mirror and the 2k×2k EUV CMOS imaging camera and to take full-disk solar images at the Ne VII 46.5 nm spectral line with a filter width of~3 nm.SUTRI employs a Ritchey-Chrétien optical system with an aperture of 18 cm.The on-orbit observations show that SUTRI images have a field of view of~416×416 and a moderate spatial resolution of~8″without an image stabilization system.The normal cadence of SUTRI images is 30 s and the solar observation time is about16 hr each day because the earth eclipse time accounts for about 1/3 of SATech-01's orbit period.Approximately15 GB data is acquired each day and made available online after processing.SUTRI images are valuable as the Ne VII 46.5 nm line is formed at a temperature regime of~0.5 MK in the solar atmosphere,which has rarely been sampled by existing solar imagers.SUTRI observations will establish connections between structures in the lower solar atmosphere and corona,and advance our understanding of various types of solar activity such as flares,filament eruptions,coronal jets and coronal mass ejections.展开更多
The Solar Upper Transition Region Imager(SUTRI)focuses on the solar transition region to achieve dynamic imaging observation of the upper transition region.In this paper,we report the optical system design,mechanical ...The Solar Upper Transition Region Imager(SUTRI)focuses on the solar transition region to achieve dynamic imaging observation of the upper transition region.In this paper,we report the optical system design,mechanical design,ultrasmooth mirror manufacture and measurement,EUV multilayer film coating,prelaunch installation and calibration for the SUTRI payload at IPOE,Tongji University.Finally,the SUTRI carried by the SATech-01 satellite was successfully set to launch.All functions of this telescope were normal,and the observation results obtained in orbit were consistent with the design.展开更多
[Objectives] To study the effect of PPARγ agonist DA on the cognitive function of AD mice as well as the mechanism.[Methods]50 Kunming male mice were randomly divided into normal control group,model group and decanoi...[Objectives] To study the effect of PPARγ agonist DA on the cognitive function of AD mice as well as the mechanism.[Methods]50 Kunming male mice were randomly divided into normal control group,model group and decanoic acid administration group,the AD mice model was established by subcutaneous injection of D-galactose for 8 weeks,and the treatment group was administered orally with different doses of decanoic acid( low dose of 50 mg/kg,middle dose of 100 mg/kg,high dose of 200 mg/kg). After 8 weeks,the Morris water maze was used to detect the learning and memory capability of mice; HE staining was used to observe the morphological change of hippocampal cells in brain tissue; Western-blot and immunohistochemistry technique were used to detect the expression of PPARγ and Aβ42 protein in brain tissue; the ELISA method was used for the determination of TNF-α and i NOS level in serum. [Results]Morris water maze results showed that DA could significantly improve the learning and memory function in AD mice( P < 0. 05); HE staining showed that DA could significantly reduce degeneration in hippocampal cells; Western-blot and immunohistochemistry results showed that DA could promote the expression of PPARγ and reduce the expression of Aβ42 in brain tissue( P < 0. 05); ELISA results showed that the TNF-α,i NOS levels decreased in AD mice serum after DA treatment( P < 0. 05). [Conclusions] DA could significantly improve the cognitive function of AD mice,improve the degeneration of hippocampal cells in brain tissue,and decrease the expression of Aβ42 in brain tissue. The mechanism might be related to activation of PPARγ protein and down-regulation of expression of relevant inflammatory factors.展开更多
The stability of the flow in the vaneless diffuser of a centrifugal compressor is studied with the linear theory. The characteristics of direct and adjoint perturbation modes are investigated,and the receptivity of th...The stability of the flow in the vaneless diffuser of a centrifugal compressor is studied with the linear theory. The characteristics of direct and adjoint perturbation modes are investigated,and the receptivity of the instability mode to momentum forcing or mass injection is identified based on the adjoint modes. Analysis shows that the perturbation with the largest amplitude is located at the outlet of the vaneless diffuser, while the highest-receptivity region is located in the middle of the vaneless diffuser along the radial direction. The large difference between the direct and adjoint modes indicates that the instability mechanism cannot be identified from a study of either eigenmode separately. Therefore, the structural sensitivity analysis is adopted to study the feedback of the instability mode. The structural sensitivity of the eigenvalue which is proportional to the perturbation pressure and velocity is used to explain the mechanism of flow control for the vaneless diffuser.展开更多
基金supported by the National Natural Science Foundation of China(NSFC)under Grants 11825301,12003016,12073077the National Key R&D Program of China No.2021YFA0718600+1 种基金the Strategic Priority Research Program of the Chinese Academy of Sciences with the Grant No.XDA15018400the Youth Innovation Promotion Association of CAS(2023061)。
文摘The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the on-orbit performance of our newly developed Sc/Si multi-layer reflecting mirror and the 2k×2k EUV CMOS imaging camera and to take full-disk solar images at the Ne VII 46.5 nm spectral line with a filter width of~3 nm.SUTRI employs a Ritchey-Chrétien optical system with an aperture of 18 cm.The on-orbit observations show that SUTRI images have a field of view of~416×416 and a moderate spatial resolution of~8″without an image stabilization system.The normal cadence of SUTRI images is 30 s and the solar observation time is about16 hr each day because the earth eclipse time accounts for about 1/3 of SATech-01's orbit period.Approximately15 GB data is acquired each day and made available online after processing.SUTRI images are valuable as the Ne VII 46.5 nm line is formed at a temperature regime of~0.5 MK in the solar atmosphere,which has rarely been sampled by existing solar imagers.SUTRI observations will establish connections between structures in the lower solar atmosphere and corona,and advance our understanding of various types of solar activity such as flares,filament eruptions,coronal jets and coronal mass ejections.
基金the National Key R&D Program of China(2022YFF0709101)the National Natural Science Foundation of China(NSFC)under grant Nos.61621001,62105244,12003016 and 12204353.
文摘The Solar Upper Transition Region Imager(SUTRI)focuses on the solar transition region to achieve dynamic imaging observation of the upper transition region.In this paper,we report the optical system design,mechanical design,ultrasmooth mirror manufacture and measurement,EUV multilayer film coating,prelaunch installation and calibration for the SUTRI payload at IPOE,Tongji University.Finally,the SUTRI carried by the SATech-01 satellite was successfully set to launch.All functions of this telescope were normal,and the observation results obtained in orbit were consistent with the design.
基金Supported by Guangxi Experimental Animal Resource Sharing Platform Construction Project(2060499)
文摘[Objectives] To study the effect of PPARγ agonist DA on the cognitive function of AD mice as well as the mechanism.[Methods]50 Kunming male mice were randomly divided into normal control group,model group and decanoic acid administration group,the AD mice model was established by subcutaneous injection of D-galactose for 8 weeks,and the treatment group was administered orally with different doses of decanoic acid( low dose of 50 mg/kg,middle dose of 100 mg/kg,high dose of 200 mg/kg). After 8 weeks,the Morris water maze was used to detect the learning and memory capability of mice; HE staining was used to observe the morphological change of hippocampal cells in brain tissue; Western-blot and immunohistochemistry technique were used to detect the expression of PPARγ and Aβ42 protein in brain tissue; the ELISA method was used for the determination of TNF-α and i NOS level in serum. [Results]Morris water maze results showed that DA could significantly improve the learning and memory function in AD mice( P < 0. 05); HE staining showed that DA could significantly reduce degeneration in hippocampal cells; Western-blot and immunohistochemistry results showed that DA could promote the expression of PPARγ and reduce the expression of Aβ42 in brain tissue( P < 0. 05); ELISA results showed that the TNF-α,i NOS levels decreased in AD mice serum after DA treatment( P < 0. 05). [Conclusions] DA could significantly improve the cognitive function of AD mice,improve the degeneration of hippocampal cells in brain tissue,and decrease the expression of Aβ42 in brain tissue. The mechanism might be related to activation of PPARγ protein and down-regulation of expression of relevant inflammatory factors.
文摘The stability of the flow in the vaneless diffuser of a centrifugal compressor is studied with the linear theory. The characteristics of direct and adjoint perturbation modes are investigated,and the receptivity of the instability mode to momentum forcing or mass injection is identified based on the adjoint modes. Analysis shows that the perturbation with the largest amplitude is located at the outlet of the vaneless diffuser, while the highest-receptivity region is located in the middle of the vaneless diffuser along the radial direction. The large difference between the direct and adjoint modes indicates that the instability mechanism cannot be identified from a study of either eigenmode separately. Therefore, the structural sensitivity analysis is adopted to study the feedback of the instability mode. The structural sensitivity of the eigenvalue which is proportional to the perturbation pressure and velocity is used to explain the mechanism of flow control for the vaneless diffuser.
