Carbyne delivers various excellent properties for the existence of the larger number of sp-hybridized carbon atoms.Here,a 3D well-defined porous carbon material germanium-carbdiyne(Ge-CDY)which is comprised of only sp...Carbyne delivers various excellent properties for the existence of the larger number of sp-hybridized carbon atoms.Here,a 3D well-defined porous carbon material germanium-carbdiyne(Ge-CDY)which is comprised of only sp-hybridized carbon atoms bridging by Ge atoms has been developed and investigated.The unique diamond-like structure constructed by linear butadiyne bonds and sp 3-hybridized Ge atoms ensures the stability of Ge-CDY.The large percentage of conjugated alkyne bonds composed of sp-C guarantees the good conductivity and the low band gap,which were further confirmed experimentally and theoretically,endowing Ge-CDY with the potential in electrochemical applications.The well-defined 3D carbon skeleton of Ge-CDY provides abundant uniform nanopores,which is suitable for metal ions storage and diffusion.Further half-cell evaluation also demonstrated Ge-CDY exhibited an excellent performance in lithium storage.All those indicating sp-hybridized carbon-based materials can exhibit great potential to possess excellent properties and be applied in the field of energy,electronic,and so on.展开更多
The head-related transfer function(HRTF)plays a vital role in immersive virtual reality and augmented reality technologies,especially in spatial audio synthesis for binaural reproduction.This article proposes a deep l...The head-related transfer function(HRTF)plays a vital role in immersive virtual reality and augmented reality technologies,especially in spatial audio synthesis for binaural reproduction.This article proposes a deep learning method with generic HRTF amplitudes and anthropometric parameters as input features for individual HRTF generation.By designing fully convolutional neural networks,the key anthropometric parameters and the generic HRTF amplitudes were used to predict each individual HRTF amplitude spectrum in the full-space directions,and the interaural time delay(ITD)was predicted by the transformer module.In the amplitude prediction model,the attention mechanism was adopted to better capture the relationship of HRTF amplitude spectra at two distinctive directions with large angle differences in space.Finally,with the minimum phase model,the predicted amplitude spectrum and ITDs were used to obtain a set of individual head-related impulse responses.Besides the separate training of the HRTF amplitude and ITD generation models,their joint training was also considered and evaluated.The root-mean-square error and the log-spectral distortion were selected as objective measurement metrics to evaluate the performance.Subjective experiments further showed that the auditory source localisation performance of the proposed method was better than other methods in most cases.展开更多
Objective:To classify the subtypes of metabolic-associated fatty liver disease(MAFLD)and provide new insights into the heterogeneity of MAFLD.Methods:Electronic medical records(EMR)of MAFLD diagnosed in accordance wit...Objective:To classify the subtypes of metabolic-associated fatty liver disease(MAFLD)and provide new insights into the heterogeneity of MAFLD.Methods:Electronic medical records(EMR)of MAFLD diagnosed in accordance with the diagnostic criteria of Hubei Provincial Hospital of Traditional Chinese Medicine from 2016-2020 were included in the study.for physical annotation,and the data on each clinical phenotype was normalized according to corresponding aspirational standards.The MAFLD heterogeneous medical record network(HEMnet)was constructed using sex,age,disease diagnosis,symptoms,and Western medicine prescriptions as nodes and the co-occurrence times between phenotypes as edges.K-means clustering was used for disease classification.Relative risk(RR)was used to assess the specificity of each phenotype.Statistical methods were used to compare differences in laboratory indicators among subtypes.Results:A total of patients(12,626)with a mean age of 55.02(±14.21)years were included in the study.MAFLD can be divided into five subtypes:digestive diseases(C0),mental disorders and gynecological diseases(C1),chronic liver diseases and decompensated complications(C2),diabetes mellitus and its complications(C3),and immune joint system diseases(C4).Conclusions:Patients with MAFLD experience various symptoms and complications.The classification of MAFLD based on the HEMnet method is highly reliable.展开更多
The electrocatalytic conversion of reactive nitrogen species to ammonia is a promising strategy for efficient NH_(3) synthesis.In this study,we reveal that the hybrid Cu^(+)/Cu~0 interface is catalytically active for ...The electrocatalytic conversion of reactive nitrogen species to ammonia is a promising strategy for efficient NH_(3) synthesis.In this study,we reveal that the hybrid Cu^(+)/Cu~0 interface is catalytically active for electrochemical ammonia synthesis from nitrate reduction.To maintain the hybrid Cu^(+)/Cu~0 state at negative reaction potentials,hydrophilic zeolite is used to modify Cu/Cu_(2)O electrocatalyst,which demonstrates an impressive NH_(3) production rate of 41.65 mg h^(-1) cm^(-2)with ~100% Faradaic efficiency of ammonia synthesis at-0.6 V vs.RHE.In-situ Raman spectroscopy unveil the high activity originates from the zeolite reconstruction at the electrode–electrolyte interface,which protects the valence state of Cu~0/Cu^(+) site under negative potential and promotes electrochemical activity towards NH_(3) synthesis.展开更多
Two types of silicon carbide fibers with sinusoidal electrical resistivity were prepared by using different pyrolysis technology. The relationship between the microstructure and the electrical resistivity of these fib...Two types of silicon carbide fibers with sinusoidal electrical resistivity were prepared by using different pyrolysis technology. The relationship between the microstructure and the electrical resistivity of these fibers was investigated and compared. The results indicated that carbon layer was the main conductive phase in the SiC fibers obtained by means of one step pyrolysis, whereas a free carbon phase governed the conductivity of the SiC fibers prepared through two step pyrolysis mode.展开更多
What factors fundamentally determine the value of superconducting transition temperature Tc in high temperature superconductors has been the subject of intense debate.Following the establishment of an empirical law kn...What factors fundamentally determine the value of superconducting transition temperature Tc in high temperature superconductors has been the subject of intense debate.Following the establishment of an empirical law known as Homes'law,there is a growing consensus in the community that the Tc value of the cuprate superconductors is closely linked to the superfluid density(ρ_(s))of its ground state and the conductivity(σ)of its normal state.However,all the data supporting this empirical law(ρ_(s)=AσT_(c))have been obtained from the ambientpressure superconductors.In this study,we present the first high-pressure results about the connection of the quantities of ρ_(s) and σ with T_(c),through the studies on the Bi_(1.74)Pb_(0.38)Sr_(1.88)CuO_(6+δ)and Bi_(2)Sr_(2)CaCu_(2)O_(8+δ),in which the value of their high-pressure resistivity(ρ=1/σ)is achieved by adopting our newly established method,while the quantity ofρs is extracted using Homes'law.We highlight that the Tc values are strongly linked to the joint response factors of magnetic field and electric field,i.e.,ρ_(s) and σ,respectively,implying that the physics determining T_(c) is governed by the intrinsic electromagnetic fields of the system.展开更多
Tuning the coordination atoms of central metal is an effective means to improve the electrocatalytic activity of atomic catalysts.Herein,iridium(Ir) is proposed to be asymmetrically anchored by sp-N and pyridinic N of...Tuning the coordination atoms of central metal is an effective means to improve the electrocatalytic activity of atomic catalysts.Herein,iridium(Ir) is proposed to be asymmetrically anchored by sp-N and pyridinic N of hydrogen-substituted graphdiyne(HsGDY),and coordinated with OH as an Ir atomic catalyst(Ir_(1)-N-HsGDY).The electron structures,especially the d-band center of Ir atom,are optimized by these specific coordination atoms.Thus,the as-synthesized Ir_(1)-N-HsGDY exhibits excellent electrocatalytic performances for oxygen reduction and hydrogen evolution reactions in both acidic and alkaline media.Benefiting from the unique structure of HsGDY,IrN_(2)(OH)_(3) has been developed and demonstrated to act as the active site in these electrochemical reactions.All those indicate the fresh role of the sp-N in graphdiyne in producing a new anchor way and contributing to promote the electrocatalytic activity,showing a new strategy to design novel electrochemical catalysts.展开更多
High purity and ultrafine DAAF(u-DAAF)is an emerging insensitive charge in initiators.Although there are many ways to obtain u-DAAF,developing a preparation method with stable operation,accurate control,good quality c...High purity and ultrafine DAAF(u-DAAF)is an emerging insensitive charge in initiators.Although there are many ways to obtain u-DAAF,developing a preparation method with stable operation,accurate control,good quality consistency,equipment miniaturization,and minimum manpower is an inevitable requirement to adapt to the current social technology development trend.Here reported is the microfluidic preparation of u-DAAF with tunable particle size by a passive swirling microreactor.Under the guidance of recrystallization growth kinetics and mixing behavior of fluids in the swirling microreactor,the key parameters(liquid flow rate,explosive concentration and crystallization temperature)were screened and optimized through screening experiments.Under the condition that no surfactant is added and only experimental parameters are controlled,the particle size of recrystallized DAAF can be adjusted from 98 nm to 785 nm,and the corresponding specific surface area is 8.45 m^(2)·g^(-1)to 1.33 m^(2)·g^(-1).In addition,the preparation method has good batch stability,high yield(90.8%-92.6%)and high purity(99.0%-99.4%),indicating a high practical application potential.Electric explosion derived flyer initiation tests demonstrate that the u-DAAF shows an initiation sensitivity much lower than that of the raw DAAF,and comparable to that of the refined DAAF by conventional spraying crystallization method.This study provides an efficient method to fabricate u-DAAF with narrow particle size distribution and high reproducibility as well as a theoretical reference for fabrication of other ultrafine explosives.展开更多
Auxin plays a crucial role in all aspects of plant growth and development.Auxin can induce the rapid and efficient expression of some genes,which are named auxin early response genes(AERGs),mainly including the three ...Auxin plays a crucial role in all aspects of plant growth and development.Auxin can induce the rapid and efficient expression of some genes,which are named auxin early response genes(AERGs),mainly including the three families:auxin/indole-3-acetic acid(Aux/IAA),Gretchen Hagen 3(GH3),and small auxin-up RNA(SAUR).Aux/IAA encodes the Aux/IAA protein,which is a negative regulator of auxin response.Aux/IAA and auxin response factor(ARF)form a heterodimer and participate in a variety of physiological processes through classical or non-classical auxin signaling pathways.The GH3 encodes auxin amide synthetase,which catalyzes the binding of auxin to acyl-containing small molecule substrates(such as amino acids and jasmonic acid),and regulates plant growth and stresses by regulating auxin homeostasis.SAURs is a class of small auxin up-regulated RNAs.SAUR response to auxin is complex,and the process may occur at the transcriptional,post-transcriptional and protein levels.With the development of multi-omics,significant progress has been made in the study of Aux/IAA,GH3,and SAUR genes,but there are still many unknowns.This review offers insight into the characteristics of Aux/IAA,GH3,and SAUR gene families,and their roles in roots,hypocotyls,leaves,leaf inclinations,flowers,seed development,stress response,and phytohormone crosstalk,and provides clues for future research on phytohormone signaling and the molecular design breeding of crops.展开更多
To assess the effects of river damming on dissolved inorganic carbon in the Jialing River, a total of 40 water samples, including inflow, outflow, and stratified water in four cascade reservoirs(Tingzikou, Xinzheng,Do...To assess the effects of river damming on dissolved inorganic carbon in the Jialing River, a total of 40 water samples, including inflow, outflow, and stratified water in four cascade reservoirs(Tingzikou, Xinzheng,Dongxiguan, Caojie) were collected in January and July,2016. The major cations, anions, and δ^(13)C_(DIC) values were analyzed. It was found that the dissolved compositions are dominated by carbonate weathering, while sulfuric acids may play a relatively important role during carbonate weathering and increasing DIC concentration. Different reservoirs had variable characteristics of water physiochemical stratification. The DIC concentrations of reservoir water were lower in summer than those in winter due to the dilute effects and intensive aquatic photosynthesis, as well as imported tributaries. The δ^(13)C_(DIC) values in Tingzikou Reservoir were higher during summer than those in winter,which indicated that intensive photosynthesis increased the δ^(13)C_(DIC) values in residual water, but a similar trend was not obvious in other reservoirs. Except for in Xinzheng Reservoir, the δ^(13)C_(DIC) values in inflow and outflow reservoir water were lower than those in the surface water of stratified sampling in summer. For stratified sampling, it could be found that, in summer, the Tingzikou Reservoir δ^(13)C_(DIC) values significantly decreased with water depthdue to the anaerobic breakdown of organic matter. The significant correlation(p<0.01 or 0.05) between the DIC concentrations, the δ^(13)C_(DIC) values and anthropogenic species(Na^++K^+, Cl~–, SO_4^(2-) and NO_3^-) showed that the isotope composition of DIC can be a useful tracer of contaminants. In total, Tingzikou Reservoir showed lacustrine features, Xinzheng Reservoir and Dongxiguan Reservoir had "transitional'' features, and Caojie Reservoir had a total of "fluvial'' features. Generally, cascade reservoirs in the Jialing River exhibited natural river features rather than typical lake features due to characteristics of reservoir water in physiochemical stratification, spatiotemporal variations of DIC concentrations and isotopic compositions. It is evident that the dissolved inorganic carbon dynamics of natural rivers had been partly remolded by dam building.展开更多
A flexible counter electrode(CE) for dye-sensitized solar cells(DSCs) has been fabricated using a micro-porous polyvinylidene fluoride membrane as support media and sputtered Pt as the catalytic material.Non-conventio...A flexible counter electrode(CE) for dye-sensitized solar cells(DSCs) has been fabricated using a micro-porous polyvinylidene fluoride membrane as support media and sputtered Pt as the catalytic material.Non-conventional structure DSCs have been developed by the fabricated CEs. The Pt metal was sputtered onto one surface of the membrane as the catalytic material. DSCs were assembled by attaching the Ti O2 electrode to the membrane surface without Pt coating. The membrane was with cylindrical pore geometry. It served not only as a substrate for the CE but also as a spacer for the DSC. The fabricated DSC with the flexible membrane CE showed higher photocurrent density than the conventional sandwich devices based on chemically deposited Pt/FTO glass, achieving a photovoltaic conversion efficiency of 4.43%. The results provides useful information in investigation and development of stable, low-cost, simple-design, flexible and lightweight DSCs.展开更多
Dynamic stability analysis of superconducting electro-dynamic maglev train under lateral and yawing motion condition is the key research content.The novel three-dimensional electromagnetic model of integrated linear s...Dynamic stability analysis of superconducting electro-dynamic maglev train under lateral and yawing motion condition is the key research content.The novel three-dimensional electromagnetic model of integrated linear synchronous motor in electro-dynamic maglev train with yawing operation condition is proposed,which can not only simultaneously achieve the propulsion,levitation and guidance performances of maglev vehicle,but also analyze the dynamic stability performance of train with yawing condition.The three-dimensional analytical method is introduced for analyzing the electromagnetic force characteristics of the linear synchronous motor with the yawing operation condition.Firstly,the topology structure and operation principle of the linear synchronous motor with yawing attitude are proposed.Secondly,the three-dimensional analytical model and expressions of electromagnetic characteristics are obtained by equivalent circuit method and Fourier decomposition method,such as levitation force,guidance force,propulsion force and yawing torque,etc.Finally,the three-dimensional electromagnetic characteristics of the linear synchronous motor are calculated under yawing operation conditions of maglev train,and the correctness of the analytical theory is verified by the finite element analysis and measured data on the test line.展开更多
The use of atmospheric rotating gliding arc(RGA)plasma is proposed as a facile,scalable and catalyst-free approach to synthesizing hydrogen(H2)and graphene sheets from coalbed methane(CBM).CH4 is used as a CBM surroga...The use of atmospheric rotating gliding arc(RGA)plasma is proposed as a facile,scalable and catalyst-free approach to synthesizing hydrogen(H2)and graphene sheets from coalbed methane(CBM).CH4 is used as a CBM surrogate.Based on a previous investigation of discharge properties,product distribution and energy efficiency,the operating parameters such as CH4 concentration,applied voltage and gas flow rate can effectively affect the CH4 conversion rate,the selectivity of H2 and the properties of solid generated carbon.Nevertheless,the basic properties of RGA plasma and its role in CH4 conversion are scarcely mentioned.In the present work,a 3D RGA model,with a detailed nonequilibrium CH4/Ar plasma chemistry,is developed to validate the previous experiments on CBM conversion,aiming in particular at the distribution of H2 and other gas products.Our results demonstrate that the dynamics of RGA is derived from the joint effects of electron convection,electron migration and electron diffusion,and is prominently determined by the variation of the gas flow rate and applied voltage.Subsequently,a combined experimental and chemical kinetical simulation is performed to analyze the selectivity of gas products in an RGA reaction,taking into consideration the formation and loss pathways of crucial targeted substances(such as CH4,C2H2,H2 and H radicals)and corresponding contribution rates.Additionally,the effects of operating conditions on the properties of solid products are investigated by scanning electron microscopy(SEM)and Raman spectroscopy.The results show that increasing the applied voltage and decreasing CH4 concentration will change the solid carbon from its initial spherical structure into folded multilayer graphene sheets,while the size of the graphene sheets is slightly affected by the change in gas flow rate.展开更多
Indirect approaches to estimation of biomass factors are often applied to measure carbon flux in the forestry sector. An assumption underlying a country-level carbon stock estimate is the representativeness of these f...Indirect approaches to estimation of biomass factors are often applied to measure carbon flux in the forestry sector. An assumption underlying a country-level carbon stock estimate is the representativeness of these factors. Although intensive studies have been conducted to quantify biomass factors, each study typically covers a limited geographic area. The goal of this study was to employ a meta-analysis approach to develop regional bio- mass factors for Quercus mongolica forests in South Korea. The biomass factors of interest were biomass conversion and expansion factor （BCEF）, biomass expansion factor （BEF） and root-to-shoot ratio （RSR）. Our objectives were to select probability density functions （PDFs） that best fitted the three biomass factors and to quantify their means and uncertainties. A total of 12 scientific publications were selected as data sources based on a set of criteria. Fromthese publications we chose 52 study sites spread out across South Korea. The statistical model for the meta- analysis was a multilevel model with publication （data source） as the nesting factor specified under the Bayesian framework. Gamma, Log-normal and Weibull PDFs were evaluated. The Log-normal PDF yielded the best quanti- tative and qualitative fit for the three biomass factors. However, a poor fit of the PDF to the long right tail of observed BEF and RSR distributions was apparent. The median posterior estimates for means and 95 % credible intervals for BCEF, BEF and RSR across all 12 publica- tions were 1.016 （0.800-1.299）, 1.414 （1.304-1.560） and 0.260 （0.200-0.335）, respectively. The Log-normal PDF proved useful for estimating carbon stock of Q. mongolica forests on a regional scale and for uncertainty analysis based on Monte Carlo simulation.展开更多
This article reviews the research progress of measurement techniques and materials on the mechanocaloric effect over the past few decades.Mechanocaloric materials can be divided into elastocaloric and barocaloric mate...This article reviews the research progress of measurement techniques and materials on the mechanocaloric effect over the past few decades.Mechanocaloric materials can be divided into elastocaloric and barocaloric materials depending on the applied uniaxial stress or hydrostatic pressure.Elastocaloric materials include non-magnetic shape memory alloys,polymers,and rare-earth compounds.Barocaloric materials include magnetic shape memory alloys,ferroelectric ceramics,superionic conductors,and oxyfluorides.The mechanocaloric effects of these classes of materials are systematically compared in terms of the isothermal entropy change and adiabatic temperature change.In addition to the thermal effects,other characteristics closely related to the application of mechanocaloric materials are also summarized.Finally,perspectives for further development of mechanocaloric materials in the solid-state cooling area are discussed.展开更多
Silica aerogels are light weight, nanostructured, and highly porous materials with an open pore structure. Due to their excellent characteristics, such as extremely low thermal conductivity, low density and high poros...Silica aerogels are light weight, nanostructured, and highly porous materials with an open pore structure. Due to their excellent characteristics, such as extremely low thermal conductivity, low density and high porosity, the silica aerogels become promising potential adsorbents, catalysts, thermal insulation, and acoustic absorption materials for environmental purposes. This paper presents the synthesis of a highly flexible polymer modified silica aerogel with the use of a cellulose-methyltriethoxysilane (MTES) precursor in a two-step acid-base catalyzed sol-gel process. The physical properties of the resulting aerogels were characterized by thermogravimetry, scanning electron microscopy, nitrogen adsorption-desorption, contact angle, thermal conductivity measurements, compression testing and Fourier transform infrared spectroscopy. The fabricated aerogel exhibited high flexibility with a Young’s modulus of compression of 0.33 MPa and the density of 0.132 g/cm3. They were hydrophobic in nature and had low thermal conductivity. Preparation of aerogel with solid waste (fly ash/bottom ash) is also discussed. The preliminary results showed that the materials have great potential for environmental application, i.e. enhancement of solid waste recycling rate by converting waste to high value-added materials, super thermal and acoustic insulation materials in green building and removal of oil spilled into surface drainage.展开更多
Rapeseed(Brassica napus)is an oil crop grown worldwide,making it a key plant species in molecular breeding research.However,the complexity of its polyploid genome increases sequencing costs and reduces sequencing accu...Rapeseed(Brassica napus)is an oil crop grown worldwide,making it a key plant species in molecular breeding research.However,the complexity of its polyploid genome increases sequencing costs and reduces sequencing accuracy.Target capture coupled with high-throughput sequencing is an efficient approach for detecting genetic variation at genomic regions or loci of interest.In this study,588 resequenced accessions of rapeseed were used to develop a target capture sequencing SNP genotyping platform named BnaPan50T.The platform comprised 54,765,with 54,058 resequenced markers from the pan-genome,and 855 variant trait-associated markers for 12 agronomic traits.The capture quality of BnaPan50T was demonstrated well in 12 typical accessions.Compared with a conventional genotyping array,BnaPan50T has a high SNP density and a high proportion of SNPs in unique physical positions and in annotated functional genes,promising wide application.Target capture sequencing and wholegenome resequencing in 90 doubled-haploid lines yielded 60%specificity,78%uniformity within tenfold coverage range,and 93%genotyping accuracy for the platform.BnaPan50T was used to construct a genetic map for quantitative trait loci(QTL)mapping,identify 21 unique QTL,and predict several candidate genes for yield-related traits in multiple environments.A set of 132 core SNP loci was selected from BnaPan50T to construct DNA fingerprints and germplasm identification resources.This study provides genomics resources to support target capture sequencing,genetic analysis and genomic breeding of rapeseed.展开更多
基金This study was supported by the National Natural Science Foundation of China (21701182,51822208,21771187,21790050,and 21790051)the Frontier Science Research Project (QYZDB-SSW-JSC052)+1 种基金the Chinese Academy of Sciences,the Taishan Scholars Program of Shandong Province (tsqn201812111)Institute Research Project (QIBEBT ZZBS 201809).
文摘Carbyne delivers various excellent properties for the existence of the larger number of sp-hybridized carbon atoms.Here,a 3D well-defined porous carbon material germanium-carbdiyne(Ge-CDY)which is comprised of only sp-hybridized carbon atoms bridging by Ge atoms has been developed and investigated.The unique diamond-like structure constructed by linear butadiyne bonds and sp 3-hybridized Ge atoms ensures the stability of Ge-CDY.The large percentage of conjugated alkyne bonds composed of sp-C guarantees the good conductivity and the low band gap,which were further confirmed experimentally and theoretically,endowing Ge-CDY with the potential in electrochemical applications.The well-defined 3D carbon skeleton of Ge-CDY provides abundant uniform nanopores,which is suitable for metal ions storage and diffusion.Further half-cell evaluation also demonstrated Ge-CDY exhibited an excellent performance in lithium storage.All those indicating sp-hybridized carbon-based materials can exhibit great potential to possess excellent properties and be applied in the field of energy,electronic,and so on.
基金National Key Research&Development,R&D Program of China,Grant/Award Number:2021YFB3201702National Natural Science Foundation of China,Grant/Award Number:12074403。
文摘The head-related transfer function(HRTF)plays a vital role in immersive virtual reality and augmented reality technologies,especially in spatial audio synthesis for binaural reproduction.This article proposes a deep learning method with generic HRTF amplitudes and anthropometric parameters as input features for individual HRTF generation.By designing fully convolutional neural networks,the key anthropometric parameters and the generic HRTF amplitudes were used to predict each individual HRTF amplitude spectrum in the full-space directions,and the interaural time delay(ITD)was predicted by the transformer module.In the amplitude prediction model,the attention mechanism was adopted to better capture the relationship of HRTF amplitude spectra at two distinctive directions with large angle differences in space.Finally,with the minimum phase model,the predicted amplitude spectrum and ITDs were used to obtain a set of individual head-related impulse responses.Besides the separate training of the HRTF amplitude and ITD generation models,their joint training was also considered and evaluated.The root-mean-square error and the log-spectral distortion were selected as objective measurement metrics to evaluate the performance.Subjective experiments further showed that the auditory source localisation performance of the proposed method was better than other methods in most cases.
基金supported by grants from the Key project Natural Science Foundation of Hubei Province(No.2020CFA023)Project of the State Administration of Traditional Chinese Medicine(No Z155080000004):Key Laboratory of Liver and Kidney Treatment of Chronic Liver Diseases.
文摘Objective:To classify the subtypes of metabolic-associated fatty liver disease(MAFLD)and provide new insights into the heterogeneity of MAFLD.Methods:Electronic medical records(EMR)of MAFLD diagnosed in accordance with the diagnostic criteria of Hubei Provincial Hospital of Traditional Chinese Medicine from 2016-2020 were included in the study.for physical annotation,and the data on each clinical phenotype was normalized according to corresponding aspirational standards.The MAFLD heterogeneous medical record network(HEMnet)was constructed using sex,age,disease diagnosis,symptoms,and Western medicine prescriptions as nodes and the co-occurrence times between phenotypes as edges.K-means clustering was used for disease classification.Relative risk(RR)was used to assess the specificity of each phenotype.Statistical methods were used to compare differences in laboratory indicators among subtypes.Results:A total of patients(12,626)with a mean age of 55.02(±14.21)years were included in the study.MAFLD can be divided into five subtypes:digestive diseases(C0),mental disorders and gynecological diseases(C1),chronic liver diseases and decompensated complications(C2),diabetes mellitus and its complications(C3),and immune joint system diseases(C4).Conclusions:Patients with MAFLD experience various symptoms and complications.The classification of MAFLD based on the HEMnet method is highly reliable.
基金the support from the Fundamental Research Funds for the Central Universities (2022LHJH01-03, 2022ZFJH04, 2022QZJH14)Pioneer R&D Program of Zhejiang Province (2022C03040)+1 种基金the Ecological civilization project, Zhejiang Universitythe support from A Project Supported by Scientific Research Fund of Zhejiang University (XY2022013)。
文摘The electrocatalytic conversion of reactive nitrogen species to ammonia is a promising strategy for efficient NH_(3) synthesis.In this study,we reveal that the hybrid Cu^(+)/Cu~0 interface is catalytically active for electrochemical ammonia synthesis from nitrate reduction.To maintain the hybrid Cu^(+)/Cu~0 state at negative reaction potentials,hydrophilic zeolite is used to modify Cu/Cu_(2)O electrocatalyst,which demonstrates an impressive NH_(3) production rate of 41.65 mg h^(-1) cm^(-2)with ~100% Faradaic efficiency of ammonia synthesis at-0.6 V vs.RHE.In-situ Raman spectroscopy unveil the high activity originates from the zeolite reconstruction at the electrode–electrolyte interface,which protects the valence state of Cu~0/Cu^(+) site under negative potential and promotes electrochemical activity towards NH_(3) synthesis.
文摘Two types of silicon carbide fibers with sinusoidal electrical resistivity were prepared by using different pyrolysis technology. The relationship between the microstructure and the electrical resistivity of these fibers was investigated and compared. The results indicated that carbon layer was the main conductive phase in the SiC fibers obtained by means of one step pyrolysis, whereas a free carbon phase governed the conductivity of the SiC fibers prepared through two step pyrolysis mode.
基金supported by the National Key Research and Development Program of China(Grant Nos.2021YFA1401800 and 2022YFA1403900)the National Natural Science Foundation of China(Grant Nos.U2032214,12122414,12104487,and 12004419)+1 种基金the Strategic Priority Research Program(B)of the Chinese Academy of Sciences(Grant No.XDB25000000)supported by the US Department of Energy,Office of Basic Energy Sciences(Grant No.DOE-sc0012704)。
文摘What factors fundamentally determine the value of superconducting transition temperature Tc in high temperature superconductors has been the subject of intense debate.Following the establishment of an empirical law known as Homes'law,there is a growing consensus in the community that the Tc value of the cuprate superconductors is closely linked to the superfluid density(ρ_(s))of its ground state and the conductivity(σ)of its normal state.However,all the data supporting this empirical law(ρ_(s)=AσT_(c))have been obtained from the ambientpressure superconductors.In this study,we present the first high-pressure results about the connection of the quantities of ρ_(s) and σ with T_(c),through the studies on the Bi_(1.74)Pb_(0.38)Sr_(1.88)CuO_(6+δ)and Bi_(2)Sr_(2)CaCu_(2)O_(8+δ),in which the value of their high-pressure resistivity(ρ=1/σ)is achieved by adopting our newly established method,while the quantity ofρs is extracted using Homes'law.We highlight that the Tc values are strongly linked to the joint response factors of magnetic field and electric field,i.e.,ρ_(s) and σ,respectively,implying that the physics determining T_(c) is governed by the intrinsic electromagnetic fields of the system.
基金supported by the National Natural Science Foundation of China(22172090,21790051)the National Key Research and Development Project of China(2022YFA1204500,2022YFA1204501)+2 种基金the Natural Science Foundation of Shan-dong Province(ZR2021MB015)the Open Funds of the State Key Laboratory of Electroanalytical Chemistry(SKLEAC202202)the Young Scholars Program of Shandong University。
文摘Tuning the coordination atoms of central metal is an effective means to improve the electrocatalytic activity of atomic catalysts.Herein,iridium(Ir) is proposed to be asymmetrically anchored by sp-N and pyridinic N of hydrogen-substituted graphdiyne(HsGDY),and coordinated with OH as an Ir atomic catalyst(Ir_(1)-N-HsGDY).The electron structures,especially the d-band center of Ir atom,are optimized by these specific coordination atoms.Thus,the as-synthesized Ir_(1)-N-HsGDY exhibits excellent electrocatalytic performances for oxygen reduction and hydrogen evolution reactions in both acidic and alkaline media.Benefiting from the unique structure of HsGDY,IrN_(2)(OH)_(3) has been developed and demonstrated to act as the active site in these electrochemical reactions.All those indicate the fresh role of the sp-N in graphdiyne in producing a new anchor way and contributing to promote the electrocatalytic activity,showing a new strategy to design novel electrochemical catalysts.
基金the National Natural Science Foundation of China (Grant No.22105184)Research Fund of SWUST for PhD (Grant No.22zx7175)+1 种基金Sichuan Science and Technology Program (Grant No.2019ZDZX0013)Institute of Chemical Materials Program (Grant No.SXK-2022-03)for financial support。
文摘High purity and ultrafine DAAF(u-DAAF)is an emerging insensitive charge in initiators.Although there are many ways to obtain u-DAAF,developing a preparation method with stable operation,accurate control,good quality consistency,equipment miniaturization,and minimum manpower is an inevitable requirement to adapt to the current social technology development trend.Here reported is the microfluidic preparation of u-DAAF with tunable particle size by a passive swirling microreactor.Under the guidance of recrystallization growth kinetics and mixing behavior of fluids in the swirling microreactor,the key parameters(liquid flow rate,explosive concentration and crystallization temperature)were screened and optimized through screening experiments.Under the condition that no surfactant is added and only experimental parameters are controlled,the particle size of recrystallized DAAF can be adjusted from 98 nm to 785 nm,and the corresponding specific surface area is 8.45 m^(2)·g^(-1)to 1.33 m^(2)·g^(-1).In addition,the preparation method has good batch stability,high yield(90.8%-92.6%)and high purity(99.0%-99.4%),indicating a high practical application potential.Electric explosion derived flyer initiation tests demonstrate that the u-DAAF shows an initiation sensitivity much lower than that of the raw DAAF,and comparable to that of the refined DAAF by conventional spraying crystallization method.This study provides an efficient method to fabricate u-DAAF with narrow particle size distribution and high reproducibility as well as a theoretical reference for fabrication of other ultrafine explosives.
基金supported by the National Natural Science Foundation of China(32060451 and 32372073)the Natural Science Foundation of Inner Mongolia(2022ZD11)+1 种基金the Science-Technology Plan Project of Inner Mongolia(2023YFDZ0007)Applied Technology Research and Development Foundation of Inner Mongolia(2021PT0001).
文摘Auxin plays a crucial role in all aspects of plant growth and development.Auxin can induce the rapid and efficient expression of some genes,which are named auxin early response genes(AERGs),mainly including the three families:auxin/indole-3-acetic acid(Aux/IAA),Gretchen Hagen 3(GH3),and small auxin-up RNA(SAUR).Aux/IAA encodes the Aux/IAA protein,which is a negative regulator of auxin response.Aux/IAA and auxin response factor(ARF)form a heterodimer and participate in a variety of physiological processes through classical or non-classical auxin signaling pathways.The GH3 encodes auxin amide synthetase,which catalyzes the binding of auxin to acyl-containing small molecule substrates(such as amino acids and jasmonic acid),and regulates plant growth and stresses by regulating auxin homeostasis.SAURs is a class of small auxin up-regulated RNAs.SAUR response to auxin is complex,and the process may occur at the transcriptional,post-transcriptional and protein levels.With the development of multi-omics,significant progress has been made in the study of Aux/IAA,GH3,and SAUR genes,but there are still many unknowns.This review offers insight into the characteristics of Aux/IAA,GH3,and SAUR gene families,and their roles in roots,hypocotyls,leaves,leaf inclinations,flowers,seed development,stress response,and phytohormone crosstalk,and provides clues for future research on phytohormone signaling and the molecular design breeding of crops.
基金financially supported by the National Key Research and Development Program of China(2016YFA0601000)the National Natural Science Foundation of China(Grant No.41373136)
文摘To assess the effects of river damming on dissolved inorganic carbon in the Jialing River, a total of 40 water samples, including inflow, outflow, and stratified water in four cascade reservoirs(Tingzikou, Xinzheng,Dongxiguan, Caojie) were collected in January and July,2016. The major cations, anions, and δ^(13)C_(DIC) values were analyzed. It was found that the dissolved compositions are dominated by carbonate weathering, while sulfuric acids may play a relatively important role during carbonate weathering and increasing DIC concentration. Different reservoirs had variable characteristics of water physiochemical stratification. The DIC concentrations of reservoir water were lower in summer than those in winter due to the dilute effects and intensive aquatic photosynthesis, as well as imported tributaries. The δ^(13)C_(DIC) values in Tingzikou Reservoir were higher during summer than those in winter,which indicated that intensive photosynthesis increased the δ^(13)C_(DIC) values in residual water, but a similar trend was not obvious in other reservoirs. Except for in Xinzheng Reservoir, the δ^(13)C_(DIC) values in inflow and outflow reservoir water were lower than those in the surface water of stratified sampling in summer. For stratified sampling, it could be found that, in summer, the Tingzikou Reservoir δ^(13)C_(DIC) values significantly decreased with water depthdue to the anaerobic breakdown of organic matter. The significant correlation(p<0.01 or 0.05) between the DIC concentrations, the δ^(13)C_(DIC) values and anthropogenic species(Na^++K^+, Cl~–, SO_4^(2-) and NO_3^-) showed that the isotope composition of DIC can be a useful tracer of contaminants. In total, Tingzikou Reservoir showed lacustrine features, Xinzheng Reservoir and Dongxiguan Reservoir had "transitional'' features, and Caojie Reservoir had a total of "fluvial'' features. Generally, cascade reservoirs in the Jialing River exhibited natural river features rather than typical lake features due to characteristics of reservoir water in physiochemical stratification, spatiotemporal variations of DIC concentrations and isotopic compositions. It is evident that the dissolved inorganic carbon dynamics of natural rivers had been partly remolded by dam building.
基金supported by National Natural Science Foundation of China(No.10774046)Shanghai Municipal Science&Technology Committee(No.09JC1404600+1 种基金No.0852nm06100 and No.08230705400)Singapore Ministry of Education innovation fund(MOE IF Funding MOE2008-IF-1-016)
文摘A flexible counter electrode(CE) for dye-sensitized solar cells(DSCs) has been fabricated using a micro-porous polyvinylidene fluoride membrane as support media and sputtered Pt as the catalytic material.Non-conventional structure DSCs have been developed by the fabricated CEs. The Pt metal was sputtered onto one surface of the membrane as the catalytic material. DSCs were assembled by attaching the Ti O2 electrode to the membrane surface without Pt coating. The membrane was with cylindrical pore geometry. It served not only as a substrate for the CE but also as a spacer for the DSC. The fabricated DSC with the flexible membrane CE showed higher photocurrent density than the conventional sandwich devices based on chemically deposited Pt/FTO glass, achieving a photovoltaic conversion efficiency of 4.43%. The results provides useful information in investigation and development of stable, low-cost, simple-design, flexible and lightweight DSCs.
基金supported in part by the National Natural Science Foundation of China under Grant 52077003 and 51777009。
文摘Dynamic stability analysis of superconducting electro-dynamic maglev train under lateral and yawing motion condition is the key research content.The novel three-dimensional electromagnetic model of integrated linear synchronous motor in electro-dynamic maglev train with yawing operation condition is proposed,which can not only simultaneously achieve the propulsion,levitation and guidance performances of maglev vehicle,but also analyze the dynamic stability performance of train with yawing condition.The three-dimensional analytical method is introduced for analyzing the electromagnetic force characteristics of the linear synchronous motor with the yawing operation condition.Firstly,the topology structure and operation principle of the linear synchronous motor with yawing attitude are proposed.Secondly,the three-dimensional analytical model and expressions of electromagnetic characteristics are obtained by equivalent circuit method and Fourier decomposition method,such as levitation force,guidance force,propulsion force and yawing torque,etc.Finally,the three-dimensional electromagnetic characteristics of the linear synchronous motor are calculated under yawing operation conditions of maglev train,and the correctness of the analytical theory is verified by the finite element analysis and measured data on the test line.
基金supported by the Foundation for Innovative Research Groups of National Natural Science Foundation of China (No. 51621005)China Postdoctoral Science Foundation (No. 2018M630672)
文摘The use of atmospheric rotating gliding arc(RGA)plasma is proposed as a facile,scalable and catalyst-free approach to synthesizing hydrogen(H2)and graphene sheets from coalbed methane(CBM).CH4 is used as a CBM surrogate.Based on a previous investigation of discharge properties,product distribution and energy efficiency,the operating parameters such as CH4 concentration,applied voltage and gas flow rate can effectively affect the CH4 conversion rate,the selectivity of H2 and the properties of solid generated carbon.Nevertheless,the basic properties of RGA plasma and its role in CH4 conversion are scarcely mentioned.In the present work,a 3D RGA model,with a detailed nonequilibrium CH4/Ar plasma chemistry,is developed to validate the previous experiments on CBM conversion,aiming in particular at the distribution of H2 and other gas products.Our results demonstrate that the dynamics of RGA is derived from the joint effects of electron convection,electron migration and electron diffusion,and is prominently determined by the variation of the gas flow rate and applied voltage.Subsequently,a combined experimental and chemical kinetical simulation is performed to analyze the selectivity of gas products in an RGA reaction,taking into consideration the formation and loss pathways of crucial targeted substances(such as CH4,C2H2,H2 and H radicals)and corresponding contribution rates.Additionally,the effects of operating conditions on the properties of solid products are investigated by scanning electron microscopy(SEM)and Raman spectroscopy.The results show that increasing the applied voltage and decreasing CH4 concentration will change the solid carbon from its initial spherical structure into folded multilayer graphene sheets,while the size of the graphene sheets is slightly affected by the change in gas flow rate.
文摘Indirect approaches to estimation of biomass factors are often applied to measure carbon flux in the forestry sector. An assumption underlying a country-level carbon stock estimate is the representativeness of these factors. Although intensive studies have been conducted to quantify biomass factors, each study typically covers a limited geographic area. The goal of this study was to employ a meta-analysis approach to develop regional bio- mass factors for Quercus mongolica forests in South Korea. The biomass factors of interest were biomass conversion and expansion factor （BCEF）, biomass expansion factor （BEF） and root-to-shoot ratio （RSR）. Our objectives were to select probability density functions （PDFs） that best fitted the three biomass factors and to quantify their means and uncertainties. A total of 12 scientific publications were selected as data sources based on a set of criteria. Fromthese publications we chose 52 study sites spread out across South Korea. The statistical model for the meta- analysis was a multilevel model with publication （data source） as the nesting factor specified under the Bayesian framework. Gamma, Log-normal and Weibull PDFs were evaluated. The Log-normal PDF yielded the best quanti- tative and qualitative fit for the three biomass factors. However, a poor fit of the PDF to the long right tail of observed BEF and RSR distributions was apparent. The median posterior estimates for means and 95 % credible intervals for BCEF, BEF and RSR across all 12 publica- tions were 1.016 （0.800-1.299）, 1.414 （1.304-1.560） and 0.260 （0.200-0.335）, respectively. The Log-normal PDF proved useful for estimating carbon stock of Q. mongolica forests on a regional scale and for uncertainty analysis based on Monte Carlo simulation.
基金Project supported by the National Natural Science Foundation of China(Grant No.11474280).
文摘This article reviews the research progress of measurement techniques and materials on the mechanocaloric effect over the past few decades.Mechanocaloric materials can be divided into elastocaloric and barocaloric materials depending on the applied uniaxial stress or hydrostatic pressure.Elastocaloric materials include non-magnetic shape memory alloys,polymers,and rare-earth compounds.Barocaloric materials include magnetic shape memory alloys,ferroelectric ceramics,superionic conductors,and oxyfluorides.The mechanocaloric effects of these classes of materials are systematically compared in terms of the isothermal entropy change and adiabatic temperature change.In addition to the thermal effects,other characteristics closely related to the application of mechanocaloric materials are also summarized.Finally,perspectives for further development of mechanocaloric materials in the solid-state cooling area are discussed.
文摘Silica aerogels are light weight, nanostructured, and highly porous materials with an open pore structure. Due to their excellent characteristics, such as extremely low thermal conductivity, low density and high porosity, the silica aerogels become promising potential adsorbents, catalysts, thermal insulation, and acoustic absorption materials for environmental purposes. This paper presents the synthesis of a highly flexible polymer modified silica aerogel with the use of a cellulose-methyltriethoxysilane (MTES) precursor in a two-step acid-base catalyzed sol-gel process. The physical properties of the resulting aerogels were characterized by thermogravimetry, scanning electron microscopy, nitrogen adsorption-desorption, contact angle, thermal conductivity measurements, compression testing and Fourier transform infrared spectroscopy. The fabricated aerogel exhibited high flexibility with a Young’s modulus of compression of 0.33 MPa and the density of 0.132 g/cm3. They were hydrophobic in nature and had low thermal conductivity. Preparation of aerogel with solid waste (fly ash/bottom ash) is also discussed. The preliminary results showed that the materials have great potential for environmental application, i.e. enhancement of solid waste recycling rate by converting waste to high value-added materials, super thermal and acoustic insulation materials in green building and removal of oil spilled into surface drainage.
基金supported by the National Natural Science Foundation of China(31871653 to K.L.,31830067 to J.L.)the Talent Project of Chongqing Natural Science Foundation(cstc2021ycjhbgzxm0033 to K.L.)Germplasm Creation Special Program of Southwest University.
文摘Rapeseed(Brassica napus)is an oil crop grown worldwide,making it a key plant species in molecular breeding research.However,the complexity of its polyploid genome increases sequencing costs and reduces sequencing accuracy.Target capture coupled with high-throughput sequencing is an efficient approach for detecting genetic variation at genomic regions or loci of interest.In this study,588 resequenced accessions of rapeseed were used to develop a target capture sequencing SNP genotyping platform named BnaPan50T.The platform comprised 54,765,with 54,058 resequenced markers from the pan-genome,and 855 variant trait-associated markers for 12 agronomic traits.The capture quality of BnaPan50T was demonstrated well in 12 typical accessions.Compared with a conventional genotyping array,BnaPan50T has a high SNP density and a high proportion of SNPs in unique physical positions and in annotated functional genes,promising wide application.Target capture sequencing and wholegenome resequencing in 90 doubled-haploid lines yielded 60%specificity,78%uniformity within tenfold coverage range,and 93%genotyping accuracy for the platform.BnaPan50T was used to construct a genetic map for quantitative trait loci(QTL)mapping,identify 21 unique QTL,and predict several candidate genes for yield-related traits in multiple environments.A set of 132 core SNP loci was selected from BnaPan50T to construct DNA fingerprints and germplasm identification resources.This study provides genomics resources to support target capture sequencing,genetic analysis and genomic breeding of rapeseed.
