[Objectives] The biologically active compounds of Houttuynia cordata Thunb. as a medicinal and edible plant are well documented. However, amino acid as an important indicator of the value of H. cordata is little repor...[Objectives] The biologically active compounds of Houttuynia cordata Thunb. as a medicinal and edible plant are well documented. However, amino acid as an important indicator of the value of H. cordata is little reported. [Methods] Amino acids of the H. cordata were analysed by pre-column derivatization with 2,4-dinitrochlorobenzne(CDNB) coupled to HPLC/DAD. The optimized conditions of the amino acids derivatized by CDNB were followed: 110 ℃ of hydrolysis temperature, 1∶12 of the equivalent proportion between amino acid and CDNB, 80 min of derivatization reaction time and 80 ℃ of derivatization reaction temperature. The method was used to determine the amino acids of H. cordata samples from 11 different geographical sites in Guizhou. [Results] The results suggested that the contents of 17 amino acids were quite variable at different H. cordata samples. [Conclusions] This study will provide a basis for the quality evaluation of H. cordata nutrition.展开更多
Non-alcoholic fatty liver disease(NAFLD)is a condition involving the accumulation of liver fat in excess of 5–10%of its weight after excluding excessive alcohol intake and any other causes of liver disease or steatos...Non-alcoholic fatty liver disease(NAFLD)is a condition involving the accumulation of liver fat in excess of 5–10%of its weight after excluding excessive alcohol intake and any other causes of liver disease or steatosis.1 NAFLD has increased with the occurrence of obesity,diabetes,and metabolic syndrome,due to which an international consensus of experts proposed renaming it metabolic dysfunction-associated fatty liver disease(MAFLD).展开更多
A series of carb on nano particles(CNPs)with emissi on wavele ngth ranging from 483 to 525 nm were prepared by hydrothermal treatme nt of poly-3-thiopheneacetic acid(PTA)and NaOH.The emission wavelength and surface ox...A series of carb on nano particles(CNPs)with emissi on wavele ngth ranging from 483 to 525 nm were prepared by hydrothermal treatme nt of poly-3-thiopheneacetic acid(PTA)and NaOH.The emission wavelength and surface oxidation degree of CNPs were shown to be controllable by simply adjusti ng NaOH concentration.These CNPs prese nted obvious fluoresce nee spectral response toward copper ions(Cu^2+)through static quenching caused synergistically by electron transfer and inner filter effect.The O-and S-containing groups on the surface of CNPs were dem on strated to be resp on sible for their outsta nding sensing performa nee.Based on that,a CN Ps-based ratiometric fluoresce nt probe for Cu^2+with a high fluoresce nee quenching rate constant of 1.4×10^5 L/mol and a short resp onse time(10 s)was developed.Their practical applications in detecting Cu^2+in pond water and living cells were also dem on strated.展开更多
2,7-Di（9,9-dimethyl-9H-fluoren-l-yl）-9H-thioxanthen-9-one （DMBFTX） with thermally activated delayed fluorescence （TADF） was well designed and synthesized. The phosphorescent organic lightemitting device （PHOLED...2,7-Di（9,9-dimethyl-9H-fluoren-l-yl）-9H-thioxanthen-9-one （DMBFTX） with thermally activated delayed fluorescence （TADF） was well designed and synthesized. The phosphorescent organic lightemitting device （PHOLED） based on this novel TADF host material displays a stable red phosphorescence region, a peak external quantum efficiency （EQE） value of 12.9% and a low EQE roll-off of 38.8%at a luminance of 10000 cd/m2, which is benefited from the reverse intersystem crossing （RISC） of TADF host and less populated triplet exitons. Notably, the red device based on the TADF host DMBFrX exhibits superior electroluminescence performance and reduced efficiency roll-offcompared with the one hosted by commercially available host 1,3-bis（9-carbazolyl）benzene （mCP）, illustrating the high potential of employing the TADF host material with small energy gap to reduce efficiency roll-off in PHOLED.展开更多
基金Supported by National Natural Science Foundation of China(41761010,81260641)Science and Technology Foundation of Guizhou Province of China([2017]1121)Projects of Guizhou Normal University for Scientific Research of Doctors
文摘[Objectives] The biologically active compounds of Houttuynia cordata Thunb. as a medicinal and edible plant are well documented. However, amino acid as an important indicator of the value of H. cordata is little reported. [Methods] Amino acids of the H. cordata were analysed by pre-column derivatization with 2,4-dinitrochlorobenzne(CDNB) coupled to HPLC/DAD. The optimized conditions of the amino acids derivatized by CDNB were followed: 110 ℃ of hydrolysis temperature, 1∶12 of the equivalent proportion between amino acid and CDNB, 80 min of derivatization reaction time and 80 ℃ of derivatization reaction temperature. The method was used to determine the amino acids of H. cordata samples from 11 different geographical sites in Guizhou. [Results] The results suggested that the contents of 17 amino acids were quite variable at different H. cordata samples. [Conclusions] This study will provide a basis for the quality evaluation of H. cordata nutrition.
基金supported by the Basic and Applied Basic Research Foundation of Guangdong Province(2021A1515220185).
文摘Non-alcoholic fatty liver disease(NAFLD)is a condition involving the accumulation of liver fat in excess of 5–10%of its weight after excluding excessive alcohol intake and any other causes of liver disease or steatosis.1 NAFLD has increased with the occurrence of obesity,diabetes,and metabolic syndrome,due to which an international consensus of experts proposed renaming it metabolic dysfunction-associated fatty liver disease(MAFLD).
基金This work was supported by the General Research Fund of Hong Kong(Nos.CityU 11306717,and CityU 11338516)the National Natural Science Foundation of China(Nos.61720106014 and 61805287)+2 种基金National Science Foundation of Hunan Province,China(Nos.2018JJ3632 and 2019JJ50824)Basic Research Foundation of Shenzhen Science and Technology Innovation(Nos.JCYJ20180307151245919)the Fundamental Research Funds for the Central Universities(No.202045002).
文摘A series of carb on nano particles(CNPs)with emissi on wavele ngth ranging from 483 to 525 nm were prepared by hydrothermal treatme nt of poly-3-thiopheneacetic acid(PTA)and NaOH.The emission wavelength and surface oxidation degree of CNPs were shown to be controllable by simply adjusti ng NaOH concentration.These CNPs prese nted obvious fluoresce nee spectral response toward copper ions(Cu^2+)through static quenching caused synergistically by electron transfer and inner filter effect.The O-and S-containing groups on the surface of CNPs were dem on strated to be resp on sible for their outsta nding sensing performa nee.Based on that,a CN Ps-based ratiometric fluoresce nt probe for Cu^2+with a high fluoresce nee quenching rate constant of 1.4×10^5 L/mol and a short resp onse time(10 s)was developed.Their practical applications in detecting Cu^2+in pond water and living cells were also dem on strated.
基金supported by National Natural Science Foundation of China(No. 61605158)the Science and TechnologyDepartment of Shaanxi Province(No. 2016JQ2028)the Education Department of Shaanxi Province(No. 16JK1790)
文摘2,7-Di（9,9-dimethyl-9H-fluoren-l-yl）-9H-thioxanthen-9-one （DMBFTX） with thermally activated delayed fluorescence （TADF） was well designed and synthesized. The phosphorescent organic lightemitting device （PHOLED） based on this novel TADF host material displays a stable red phosphorescence region, a peak external quantum efficiency （EQE） value of 12.9% and a low EQE roll-off of 38.8%at a luminance of 10000 cd/m2, which is benefited from the reverse intersystem crossing （RISC） of TADF host and less populated triplet exitons. Notably, the red device based on the TADF host DMBFrX exhibits superior electroluminescence performance and reduced efficiency roll-offcompared with the one hosted by commercially available host 1,3-bis（9-carbazolyl）benzene （mCP）, illustrating the high potential of employing the TADF host material with small energy gap to reduce efficiency roll-off in PHOLED.
