Advancing high-voltage stability of layered sodium-ion oxides represents a pivotal avenue for their progress in energy storage applications.Despite this,a comprehensive understanding of the mechanisms underpinning the...Advancing high-voltage stability of layered sodium-ion oxides represents a pivotal avenue for their progress in energy storage applications.Despite this,a comprehensive understanding of the mechanisms underpinning their structural deterioration at elevated voltages remains insufficiently explored.In this study,we unveil a layer delamination phenomenon of Na_(0.67)Ni_(0.3)Mn_(0.7)O_(2)(NNM)within the 2.0-4.3 V voltage,attributed to considerable volumetric fluctuations along the c-axis and lattice oxygen reactions induced by the simultaneous Ni^(3+)/Ni^(4+)and anion redox reactions.By introducing Mg doping to diminished Ni-O antibonding,the anion oxidation-reduction reactions are effectively mitigated,and the structural integrity of the P2 phase remains firmly intact,safeguarding active sites and precluding the formation of novel interfaces.The Na_(0.67)Mg_(0.05)Ni_(0.25)Mn_(0.7)O_(2)(NMNM-5)exhibits a specific capacity of100.7 mA h g^(-1),signifying an 83%improvement compared to the NNM material within the voltage of2.0-4.3 V.This investigation underscores the intricate interplay between high-voltage stability and structural degradation mechanisms in layered sodium-ion oxides.展开更多
Atlantic meridional overturning circulation(AMOC)plays an important role in transporting heat meridionally in the Earth’s climate system and is also a key metrical tool to verify oceanic general circulation models.Tw...Atlantic meridional overturning circulation(AMOC)plays an important role in transporting heat meridionally in the Earth’s climate system and is also a key metrical tool to verify oceanic general circulation models.Two OMIP(Ocean Model Intercomparison Project phase 1 and 2)simulations with LICOM3(version 3 of the LASG/IAP Climate System Ocean Model)developed at the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG),Institute of Atmospheric Physics(IAP),are compared in this study.Both simulations well reproduce the fundamental characteristics of the AMOC,but the OMIP1 simulation shows a significantly stronger AMOC than the OMIP2 simulation.Because the LICOM3 configurations are identical between these two experiments,any differences between them must be attributed to the surface forcing data.Further analysis suggests that sea surface salinity(SSS)differences should be mainly responsible for the enhanced AMOC in the OMIP1 simulation,but sea surface temperature(SST)also play an unignorable role in modulating AMOC.In the North Atlantic,where deep convection occurs,the SSS in OMIP1 is more saline than that in OMIP1.We find that in the major region of deep convection,the change of SSS has more significant effect on density than the change of SST.As a result,the SSS was more saline than that in OMIP2,leading to stronger deep convection and subsequently intensify the AMOC.We conduct a series of numerical experiments with LICOM3,and the results confirmed that the changes in SSS have more significant effect on the strength of AMOC than the changes in SST.展开更多
Plant-based fermentations provide an untapped source for novel biotechnological applications.In this study,a probiotic named Lactobacillus fermentum 21828 was introduced to ferment Lentinus edodes.Polysaccharides were...Plant-based fermentations provide an untapped source for novel biotechnological applications.In this study,a probiotic named Lactobacillus fermentum 21828 was introduced to ferment Lentinus edodes.Polysaccharides were extracted from fermented and non-fermented L.edodes and purified via DEAE-52 and Sephadex G-100.The components designated F-LEP-2a and NF-LEP-2a were analyzed by FT-IR,HPGPC,HPAEC,SEM,GC-MS and NMR.The results revealed that probiotic fermentation increased the molecular weight from 1.16×10^(4) Da to 1.87×10^(4) Da and altered the proportions of glucose,galactose and mannose,in which glucose increased from 45.94%to 48.16%.Methylation analysis and NMR spectra indicated that F-LEP-2a and NF-LEP-2a had similar linkage patterns.Furthermore,their immunomodulatory activities were evaluated with immunosuppressive mice.NF-LEP and F-LEP improved immune organ indices,immunoglobulin(Ig G and Ig M)and cytokines concentrations;restored the antioxidation capacity of liver;and maintained the balance of gut microbiota.F-LEP displayed better moderating effects on the spleen index,immunoglobulin,cytokines and the diversity of gut microbiota than NF-LEP(200,400 mg/kg).Our study provides an efficient and environment-friendly way for the structural modification of polysaccharides,which helps to enhance their biological activity and promote their wide application in food,medicine and other fields.展开更多
Quantum excitation is usually regarded as a transient process occurring instantaneously,leaving the underlying physics shrouded in mystery.Recent research shows that Rydberg-state excitation with ultrashort laser puls...Quantum excitation is usually regarded as a transient process occurring instantaneously,leaving the underlying physics shrouded in mystery.Recent research shows that Rydberg-state excitation with ultrashort laser pulses can be investigated and manipulated with state-of-the-art few-cycle pulses.We theoretically find that the efficiency of Rydberg state excitation can be enhanced with a short laser pulse and modulated by varying the laser intensities.We also uncover new facets of the excitation dynamics,including the launching of an electron wave packet through strong-field ionization,the re-entry of the electron into the atomic potential and the crucial step where the electron makes a U-turn,resulting in twin captures into Rydberg orbitals.By tuning the laser intensity,we show that the excitation of the Rydberg state can be coherently controlled on a sub-optical-cycle timescale.Our work paves the way toward ultrafast control and coherent manipulation of Rydberg states,thus benefiting Rydberg-state-based quantum technology.展开更多
In the past few years,many groups have focused on the research and development of GaN-based ultraviolet laser diodes(UV LDs).Great progresses have been achieved even though many challenges exist.In this article,we ana...In the past few years,many groups have focused on the research and development of GaN-based ultraviolet laser diodes(UV LDs).Great progresses have been achieved even though many challenges exist.In this article,we analyze the challenges of developing GaN-based ultraviolet laser diodes,and the approaches to improve the performance of ultraviolet laser diode are reviewed.With these techniques,room temperature(RT)pulsed oscillation of AlGaN UVA(ultraviolet A)LD has been realized,with a lasing wavelength of 357.9 nm.Combining with the suppression of thermal effect,the high output power of 3.8 W UV LD with a lasing wavelength of 386.5 nm was also fabricated.展开更多
Hydrogels offer tissue-like softness,stretchability,fracture toughness,ionic conductivity,and compatibility with biological tissues,which make them promising candidates for fabricating flexible bioelectronics.A soft h...Hydrogels offer tissue-like softness,stretchability,fracture toughness,ionic conductivity,and compatibility with biological tissues,which make them promising candidates for fabricating flexible bioelectronics.A soft hydrogel film offers an ideal interface to directly bridge thin-film electronics with the soft tissues.However,it remains difficult to fabricate a soft hydrogel film with an ultrathin configuration and excellent mechanical strength.Here we report a biological tissue-inspired ultrasoft microfiber composite ultrathin(<5μm)hydrogel film,which is currently the thinnest hydrogel film as far as we know.The embedded microfibers endow the composite hydrogel with prominent mechanical strength(tensile stress~6 MPa)and anti-tearing property.Moreover,our microfiber composite hydrogel offers the capability of tunable mechanical properties in a broad range,allowing for matching the modulus of most biological tissues and organs.The incorporation of glycerol and salt ions imparts the microfiber composite hydrogel with high ionic conductivity and prominent anti-dehydration behavior.Such microfiber composite hydrogels are promising for constructing attaching-type flexible bioelectronics to monitor biosignals.展开更多
High-order harmonics are ideal probes to resolve the attosecond dynamics of strong-field recollision processes.An easy-to-implement phase mask is utilized to covert the Gaussian beam to TEM01 transverse electromagneti...High-order harmonics are ideal probes to resolve the attosecond dynamics of strong-field recollision processes.An easy-to-implement phase mask is utilized to covert the Gaussian beam to TEM01 transverse electromagnetic mode,allowing the realization of two-source interferometry of high-order harmonics.We experimentally measure the intensity dependence of dipole phase directly with high-order harmonic interferometry,in which the driving laser intensity can be precisely adjusted.The classical electron excursion simulations reproduce the experimental findings quite well,demonstrating that Coulomb potential plays subtle roles on movement of electrons for harmonics near the ionization threshold.This work is of great importance for precision measurements of ultrafast dynamics in strong-field physics.展开更多
We show that it is feasible to generate sub-40-attosecond pulses with near-infrared few-cycle pulses centered at 800 nm.With proper gating technique,super-broadband continuum spectrum extending from 50 eV to above 200...We show that it is feasible to generate sub-40-attosecond pulses with near-infrared few-cycle pulses centered at 800 nm.With proper gating technique,super-broadband continuum spectrum extending from 50 eV to above 200 eV can be obtained,and the intrinsic atto-chirp can be satisfactorily compensated with C filter,producing isolated attosecond pulses with duration of 33 as.According to the wavelength scaling law of high-order harmonic generation,the proposed scheme is of great significance to develop high-flux ultrashort attosecond sources.展开更多
We demonstrate the extreme ultraviolet free induction decay emission that can be significantly enhanced by employing isolated attosecond pulses.The near infrared pulses are applied to excite the neon atoms into Rydber...We demonstrate the extreme ultraviolet free induction decay emission that can be significantly enhanced by employing isolated attosecond pulses.The near infrared pulses are applied to excite the neon atoms into Rydberg states coherently,and isolated attosecond pulses are used to manipulate populations of the Rydberg states and the subsequent free induction decay process.The time resolved experimental measurement of dependence of the resonance emission yield would help to understand the buildup dynamics of population of excited states.The enhancement assisted by attosecond pulses can serve as a mechanism to develop high-flux extreme ultraviolet light sources.展开更多
We sought to assess the incidence of aspirin resistance after off-pump coronary artery bypass(OPCAB) surgery,and investigate whether clopidogrel can improve aspirin response and be safely applied early after OPCAB sur...We sought to assess the incidence of aspirin resistance after off-pump coronary artery bypass(OPCAB) surgery,and investigate whether clopidogrel can improve aspirin response and be safely applied early after OPCAB surgery.Sixty patients who underwent standard OPCAB surgery were randomized into two groups.One group(30 patients)received mono-antiplatelet treatment(MAPT) with aspirin 100 mg daily and the other group received dual antiplatelet treatment(DAPT) with aspirin 100 mg daily plus clopidogrel 75 mg daily.Platelet aggregations in response to arachidonic acid(PL_(AA)) and adenosine diphosphate(ADP)(PL_(ADP)) were measured preoperatively and on days 1 to 6,8 and10 after the antiplatelet agents were administered.A PL_(AA) level above 20%was defined as aspirin resistance.Postoperative bleeding and other perioperative variables were also recorded.There were no significant differences between the two groups in baseline characteristics,average number of distal anastomosis,operation time,postoperative bleeding,ventilation time and postoperative hospital stay.However,the incidence of aspirin resistance was significantly lower in the DAPT group than that in the MAPT group on the first and second day after antiplatelet agents were given(62.1%vs.32.1%,34.5%vs.10.7%,respectively,both P < 0.05).There was no significant difference in postoperative complication between the two groups.DAPT with aspirin and clopidogrel can be safely applied to OPCAB patients early after the procedure.Moreover,clopidogrel reduces the incidence of OPCAB-related aspirin resistance.展开更多
Aqueous zinc-ion batteries(ZIBs)are receiving a continuously increasing attention for mobile devices,especially for the flexible and wearable electronics,due to their non-toxicity,non-flammability,and low-cost feature...Aqueous zinc-ion batteries(ZIBs)are receiving a continuously increasing attention for mobile devices,especially for the flexible and wearable electronics,due to their non-toxicity,non-flammability,and low-cost features.Despite the significant progress in achieving higher capacities for electrode materials of ZIBs,to endow them with high flexibility and economic feasibility is,however,still a significant challenge remaining unsolved.Herein,we present a highly flexible composite film composed of carbon nanotube film and V_(2)O_(5)(CNTF@V_(2)O_(5))with high strength and high conductivity,which is prepared by simply impregnating a porous CNT film with an aqueous V_(2)O_(5)sol under vacuum.For this material,intimate incorporation between V_(2)O_(5)and CNTs has been achieved,successfully integrating the high zinc ion storage capability with high mechanical flexibility.As a result,this CNTF@V_(2)O_(5)film delivers a high capacity of 356.6 m Ah g^(-1)at 0.4 A g^(-1)and excellent cycling stability with 80.1%capacity retention after 500 cycles at 2.0 A g^(-1).The novel strategy and the outstanding battery performance presented in this work should shed light on the development of high-performance and flexible ZIBs.展开更多
Under an extremely arid condition,a PVC greenhouse was built on the top of Mogao Grottoes in gobi area.The results of 235-day constant extraction of condensed water on the greenhouse film and soil water content showed...Under an extremely arid condition,a PVC greenhouse was built on the top of Mogao Grottoes in gobi area.The results of 235-day constant extraction of condensed water on the greenhouse film and soil water content showed that 2.1 g/(m2·d) groundwater moved up and exported into the soil,and a phreatic water evaporation existed in the extreme dry area where the groundwater is buried deeper than 200 m.After a prolonged export,the soil water content in the greenhouse was not lower but obviously higher than the original control ones.According to the monitored parameters including relative humidity and absolute humidity of soil,and temperature outside and inside the greenhouse,it was found that there is the available condition and mechanism for the upward movement of groundwater,and also it can be sure that the exported water was not from the soil and atmosphere outside the greenhouse.Phreatic water,an important source for soil water,interacts with atmosphere moisture via soil respiration.Soil salinity also has important effects on soil water movement and spatial-temporal heterogeneity.The extremely dry climate,terrestrial heat and change of upper soil temperature are the fundamental driving forces of water transportation and phreatic water evaporation in the Groundwater-Soil-Plant-Atmosphere Continuum(GSPAC) system.展开更多
Isolated attosecond pulses with a duration of 88 as are generated in the spectral range of 29–72 eV using double optical gating technique.The gate width is set to be shorter than half the optical cycle to avoid carri...Isolated attosecond pulses with a duration of 88 as are generated in the spectral range of 29–72 eV using double optical gating technique.The gate width is set to be shorter than half the optical cycle to avoid carrier envelop phase stabilization of the 4.2 fs driving laser pulses centered at 800 nm.The attosecond pulse duration is measured with the technique of frequency resolved optical gating for complete reconstruction of attosecond bursts.展开更多
Pore structure of hard carbon has a fundamental influence on the electrochemical properties in sodium-ion batteries(SIBs).Ultra-micropores(<0.5 nm)of hard carbon can function as ionic sieves to reduce the diffusion...Pore structure of hard carbon has a fundamental influence on the electrochemical properties in sodium-ion batteries(SIBs).Ultra-micropores(<0.5 nm)of hard carbon can function as ionic sieves to reduce the diffusion of slovated Na+but allow the entrance of naked Na^(+) into the pores,which can reduce the interficial contact between the electrolyte and the inner pores without sacrificing the fast diffusion kinetics.Herein,a molten diffusion-carbonization method is proposed to transform the micropores(>1 nm)inside carbon into ultra-micropores(<0.5 nm).Consequently,the designed carbon anode displays an enhanced capacity of 346 mAh g^(−1) at 30 mA g^(−1) with a high ICE value of~80.6%and most of the capacity(~90%)is below 1 V.Moreover,the high-loading electrode(~19 mg cm^(−2))exhibits a good temperature endurance with a high areal capacity of 6.14 mAh cm^(−2) at 25℃ and 5.32 mAh cm^(−2) at −20℃.Based on the in situ X-ray diffraction and ex situ solid-state nuclear magnetic resonance results,the designed ultra-micropores provide the extra Na+storage sites,which mainly contributes to the enhanced capacity.This proposed strategy shows a good potential for the development of high-performance SIBs.展开更多
Despite years of effort,no effective acute phase treatment has been discovered for traumatic brain injury.One impediment to successful drug development is entangled secondary injury pathways.Here we show that protein ...Despite years of effort,no effective acute phase treatment has been discovered for traumatic brain injury.One impediment to successful drug development is entangled secondary injury pathways.Here we show that protein S,a natural multifunctional protein that regulates coagulation,inflammation,and apoptosis,is able to reduce the extent of multiple secondary injuries in traumatic brain injury,and therefore improve prognosis.Mice subjected to controlled cortical impact were treated acutely(10–15 minutes post-injury)with a single dose of either protein S(1 mg/kg)or vehicle phosphate buffered saline via intravenous injection.At 24 hours post-injury,compared to the non-treated group,the protein S treated group showed substantial improvement of edema and fine motor coordination,as well as mitigation of progressive tissue loss.Immunohistochemistry and western blot targeting caspase-3,B-cell lymphoma 2(Bcl-2)along with terminal deoxynucleotidyl transferase dUTP nick end labeling(TUNEL)assay revealed that apoptosis was suppressed in treated animals.Immunohistochemistry targeting CD11 b showed limited leukocyte infiltration in the protein S-treated group.Moreover,protein S treatment increased the ipsilesional expression of aquaporin-4,which may be the underlying mechanism of its function in reducing edema.These results indicate that immediate intravenous protein S treatment after controlled cortical impact is beneficial to traumatic brain injury prognosis.Animal Use Protocols(AUPs)were approved by the University Committee on Animal Resources(UCAR)of University of Rochester Medical Center(approval No.UCAR-2008-102 R)on November 12,2013.展开更多
This paper proposes a static-output-feedback based robust fuzzy wheelbase preview control algorithm for uncertain active suspensions with time delay and finite frequency constraint.Firstly,a Takagi-Sugeno(T-S)fuzzy au...This paper proposes a static-output-feedback based robust fuzzy wheelbase preview control algorithm for uncertain active suspensions with time delay and finite frequency constraint.Firstly,a Takagi-Sugeno(T-S)fuzzy augmented model is established to formulate the half-car active suspension system with consideration of time delay,sprung mass variation and wheelbase preview information.Secondly,in view of the resonation between human’s organs and vertical vibrations in the frequency range of 4–8 Hz,a finite frequency control criterion in terms of H∞norm is developed to improve ride comfort.Meanwhile,other mechanical constraints are also considered and satisfied via generalized H2 norm.Thirdly,in order to maintain the feasibility of the controller despite of some state variables are not online-measured,a two stage approach is adopted to derive a static output feedback controller.Finally,numerical simulation results illustrate the excellent performance of the proposed controller.展开更多
基金the financial support from the National Natural Science Foundation of China(52202338)。
文摘Advancing high-voltage stability of layered sodium-ion oxides represents a pivotal avenue for their progress in energy storage applications.Despite this,a comprehensive understanding of the mechanisms underpinning their structural deterioration at elevated voltages remains insufficiently explored.In this study,we unveil a layer delamination phenomenon of Na_(0.67)Ni_(0.3)Mn_(0.7)O_(2)(NNM)within the 2.0-4.3 V voltage,attributed to considerable volumetric fluctuations along the c-axis and lattice oxygen reactions induced by the simultaneous Ni^(3+)/Ni^(4+)and anion redox reactions.By introducing Mg doping to diminished Ni-O antibonding,the anion oxidation-reduction reactions are effectively mitigated,and the structural integrity of the P2 phase remains firmly intact,safeguarding active sites and precluding the formation of novel interfaces.The Na_(0.67)Mg_(0.05)Ni_(0.25)Mn_(0.7)O_(2)(NMNM-5)exhibits a specific capacity of100.7 mA h g^(-1),signifying an 83%improvement compared to the NNM material within the voltage of2.0-4.3 V.This investigation underscores the intricate interplay between high-voltage stability and structural degradation mechanisms in layered sodium-ion oxides.
基金Supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA19060102)the National Natural Science Foundation of China(Nos.91958201,42130608)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB42000000)。
文摘Atlantic meridional overturning circulation(AMOC)plays an important role in transporting heat meridionally in the Earth’s climate system and is also a key metrical tool to verify oceanic general circulation models.Two OMIP(Ocean Model Intercomparison Project phase 1 and 2)simulations with LICOM3(version 3 of the LASG/IAP Climate System Ocean Model)developed at the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG),Institute of Atmospheric Physics(IAP),are compared in this study.Both simulations well reproduce the fundamental characteristics of the AMOC,but the OMIP1 simulation shows a significantly stronger AMOC than the OMIP2 simulation.Because the LICOM3 configurations are identical between these two experiments,any differences between them must be attributed to the surface forcing data.Further analysis suggests that sea surface salinity(SSS)differences should be mainly responsible for the enhanced AMOC in the OMIP1 simulation,but sea surface temperature(SST)also play an unignorable role in modulating AMOC.In the North Atlantic,where deep convection occurs,the SSS in OMIP1 is more saline than that in OMIP1.We find that in the major region of deep convection,the change of SSS has more significant effect on density than the change of SST.As a result,the SSS was more saline than that in OMIP2,leading to stronger deep convection and subsequently intensify the AMOC.We conduct a series of numerical experiments with LICOM3,and the results confirmed that the changes in SSS have more significant effect on the strength of AMOC than the changes in SST.
基金supported by grants from the National Key R&D Program of China(2019YFC1606701)。
文摘Plant-based fermentations provide an untapped source for novel biotechnological applications.In this study,a probiotic named Lactobacillus fermentum 21828 was introduced to ferment Lentinus edodes.Polysaccharides were extracted from fermented and non-fermented L.edodes and purified via DEAE-52 and Sephadex G-100.The components designated F-LEP-2a and NF-LEP-2a were analyzed by FT-IR,HPGPC,HPAEC,SEM,GC-MS and NMR.The results revealed that probiotic fermentation increased the molecular weight from 1.16×10^(4) Da to 1.87×10^(4) Da and altered the proportions of glucose,galactose and mannose,in which glucose increased from 45.94%to 48.16%.Methylation analysis and NMR spectra indicated that F-LEP-2a and NF-LEP-2a had similar linkage patterns.Furthermore,their immunomodulatory activities were evaluated with immunosuppressive mice.NF-LEP and F-LEP improved immune organ indices,immunoglobulin(Ig G and Ig M)and cytokines concentrations;restored the antioxidation capacity of liver;and maintained the balance of gut microbiota.F-LEP displayed better moderating effects on the spleen index,immunoglobulin,cytokines and the diversity of gut microbiota than NF-LEP(200,400 mg/kg).Our study provides an efficient and environment-friendly way for the structural modification of polysaccharides,which helps to enhance their biological activity and promote their wide application in food,medicine and other fields.
基金supported by the National Key Research and Development Program of China(Grant No.2019YFA0307703)the National Natural Science Foundation of China(Grant Nos.12234020,11874066,12274461,and 11974426)the Science and Technology Innovation Program of Hunan Province(Grant No.2022RC1193).
文摘Quantum excitation is usually regarded as a transient process occurring instantaneously,leaving the underlying physics shrouded in mystery.Recent research shows that Rydberg-state excitation with ultrashort laser pulses can be investigated and manipulated with state-of-the-art few-cycle pulses.We theoretically find that the efficiency of Rydberg state excitation can be enhanced with a short laser pulse and modulated by varying the laser intensities.We also uncover new facets of the excitation dynamics,including the launching of an electron wave packet through strong-field ionization,the re-entry of the electron into the atomic potential and the crucial step where the electron makes a U-turn,resulting in twin captures into Rydberg orbitals.By tuning the laser intensity,we show that the excitation of the Rydberg state can be coherently controlled on a sub-optical-cycle timescale.Our work paves the way toward ultrafast control and coherent manipulation of Rydberg states,thus benefiting Rydberg-state-based quantum technology.
基金This work was supported by the National Key R&D Program of China(2022YFB3605104)National Natural Science Foundation of China(62250038,61904172,61974162,62034008,62074142,and 62074140)+1 种基金Strategic Priority Research Program of Chinese Academy of Sciences(XDB43030101)Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering(2022SX-TD016).
文摘In the past few years,many groups have focused on the research and development of GaN-based ultraviolet laser diodes(UV LDs).Great progresses have been achieved even though many challenges exist.In this article,we analyze the challenges of developing GaN-based ultraviolet laser diodes,and the approaches to improve the performance of ultraviolet laser diode are reviewed.With these techniques,room temperature(RT)pulsed oscillation of AlGaN UVA(ultraviolet A)LD has been realized,with a lasing wavelength of 357.9 nm.Combining with the suppression of thermal effect,the high output power of 3.8 W UV LD with a lasing wavelength of 386.5 nm was also fabricated.
基金the funding support from the fellowship of the China Postdoctoral Science Foundation (2022M722329, 2021M700097)the National Natural Science Foundation for Distinguished Young Scholars of China (62125112)+2 种基金the National Natural Science Foundation of China (62071462, 62071463, 62271479, 22109173)the Jiangxi Provincial Natural Science Foundation (20224ACB212001)the support from Nano-X Vacuum Interconnected Workstation&Key Laboratory of Multifunctional Nanomaterials and Smart Systems of Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO),Chinese Academy of Sciences (CAS)
文摘Hydrogels offer tissue-like softness,stretchability,fracture toughness,ionic conductivity,and compatibility with biological tissues,which make them promising candidates for fabricating flexible bioelectronics.A soft hydrogel film offers an ideal interface to directly bridge thin-film electronics with the soft tissues.However,it remains difficult to fabricate a soft hydrogel film with an ultrathin configuration and excellent mechanical strength.Here we report a biological tissue-inspired ultrasoft microfiber composite ultrathin(<5μm)hydrogel film,which is currently the thinnest hydrogel film as far as we know.The embedded microfibers endow the composite hydrogel with prominent mechanical strength(tensile stress~6 MPa)and anti-tearing property.Moreover,our microfiber composite hydrogel offers the capability of tunable mechanical properties in a broad range,allowing for matching the modulus of most biological tissues and organs.The incorporation of glycerol and salt ions imparts the microfiber composite hydrogel with high ionic conductivity and prominent anti-dehydration behavior.Such microfiber composite hydrogels are promising for constructing attaching-type flexible bioelectronics to monitor biosignals.
基金supported by the National Key Research and Development Program of China(Grant No.2019YFA0307703)the National Natural Science Foundation of China(Grant Nos.12234020 and 11974426)。
文摘High-order harmonics are ideal probes to resolve the attosecond dynamics of strong-field recollision processes.An easy-to-implement phase mask is utilized to covert the Gaussian beam to TEM01 transverse electromagnetic mode,allowing the realization of two-source interferometry of high-order harmonics.We experimentally measure the intensity dependence of dipole phase directly with high-order harmonic interferometry,in which the driving laser intensity can be precisely adjusted.The classical electron excursion simulations reproduce the experimental findings quite well,demonstrating that Coulomb potential plays subtle roles on movement of electrons for harmonics near the ionization threshold.This work is of great importance for precision measurements of ultrafast dynamics in strong-field physics.
基金supported by the National Key Research and Development Program of China(Grant No.2019YFA0307703)the National Natural Science Foundation of China(Grant Nos.12234020 and 11974426)。
文摘We show that it is feasible to generate sub-40-attosecond pulses with near-infrared few-cycle pulses centered at 800 nm.With proper gating technique,super-broadband continuum spectrum extending from 50 eV to above 200 eV can be obtained,and the intrinsic atto-chirp can be satisfactorily compensated with C filter,producing isolated attosecond pulses with duration of 33 as.According to the wavelength scaling law of high-order harmonic generation,the proposed scheme is of great significance to develop high-flux ultrashort attosecond sources.
基金the National Key Research and Development Program of China(Grant No.2019YFA0307703)the National Natural Science Foundation of China(Grant Nos.11974426 and 12234020)。
文摘We demonstrate the extreme ultraviolet free induction decay emission that can be significantly enhanced by employing isolated attosecond pulses.The near infrared pulses are applied to excite the neon atoms into Rydberg states coherently,and isolated attosecond pulses are used to manipulate populations of the Rydberg states and the subsequent free induction decay process.The time resolved experimental measurement of dependence of the resonance emission yield would help to understand the buildup dynamics of population of excited states.The enhancement assisted by attosecond pulses can serve as a mechanism to develop high-flux extreme ultraviolet light sources.
基金supported by a grant from the National Natural Science Foundation of China(81170181)a Program for Development of Innovative Research Team in the First Affiliated Hospital of Nanjing Medical Universitya Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutes(PAPD)
文摘We sought to assess the incidence of aspirin resistance after off-pump coronary artery bypass(OPCAB) surgery,and investigate whether clopidogrel can improve aspirin response and be safely applied early after OPCAB surgery.Sixty patients who underwent standard OPCAB surgery were randomized into two groups.One group(30 patients)received mono-antiplatelet treatment(MAPT) with aspirin 100 mg daily and the other group received dual antiplatelet treatment(DAPT) with aspirin 100 mg daily plus clopidogrel 75 mg daily.Platelet aggregations in response to arachidonic acid(PL_(AA)) and adenosine diphosphate(ADP)(PL_(ADP)) were measured preoperatively and on days 1 to 6,8 and10 after the antiplatelet agents were administered.A PL_(AA) level above 20%was defined as aspirin resistance.Postoperative bleeding and other perioperative variables were also recorded.There were no significant differences between the two groups in baseline characteristics,average number of distal anastomosis,operation time,postoperative bleeding,ventilation time and postoperative hospital stay.However,the incidence of aspirin resistance was significantly lower in the DAPT group than that in the MAPT group on the first and second day after antiplatelet agents were given(62.1%vs.32.1%,34.5%vs.10.7%,respectively,both P < 0.05).There was no significant difference in postoperative complication between the two groups.DAPT with aspirin and clopidogrel can be safely applied to OPCAB patients early after the procedure.Moreover,clopidogrel reduces the incidence of OPCAB-related aspirin resistance.
基金supported by the National Natural Science Foundation of China(No.51072130,51502045 and 21905202)the Australian Research Council(ARC)through Discovery Project(No.DP200100365)the Discovery Early Career Researcher Award(DECRA,No.DE170100871)program。
文摘Aqueous zinc-ion batteries(ZIBs)are receiving a continuously increasing attention for mobile devices,especially for the flexible and wearable electronics,due to their non-toxicity,non-flammability,and low-cost features.Despite the significant progress in achieving higher capacities for electrode materials of ZIBs,to endow them with high flexibility and economic feasibility is,however,still a significant challenge remaining unsolved.Herein,we present a highly flexible composite film composed of carbon nanotube film and V_(2)O_(5)(CNTF@V_(2)O_(5))with high strength and high conductivity,which is prepared by simply impregnating a porous CNT film with an aqueous V_(2)O_(5)sol under vacuum.For this material,intimate incorporation between V_(2)O_(5)and CNTs has been achieved,successfully integrating the high zinc ion storage capability with high mechanical flexibility.As a result,this CNTF@V_(2)O_(5)film delivers a high capacity of 356.6 m Ah g^(-1)at 0.4 A g^(-1)and excellent cycling stability with 80.1%capacity retention after 500 cycles at 2.0 A g^(-1).The novel strategy and the outstanding battery performance presented in this work should shed light on the development of high-performance and flexible ZIBs.
基金the National Natural Science Foundation of China (40940005)
文摘Under an extremely arid condition,a PVC greenhouse was built on the top of Mogao Grottoes in gobi area.The results of 235-day constant extraction of condensed water on the greenhouse film and soil water content showed that 2.1 g/(m2·d) groundwater moved up and exported into the soil,and a phreatic water evaporation existed in the extreme dry area where the groundwater is buried deeper than 200 m.After a prolonged export,the soil water content in the greenhouse was not lower but obviously higher than the original control ones.According to the monitored parameters including relative humidity and absolute humidity of soil,and temperature outside and inside the greenhouse,it was found that there is the available condition and mechanism for the upward movement of groundwater,and also it can be sure that the exported water was not from the soil and atmosphere outside the greenhouse.Phreatic water,an important source for soil water,interacts with atmosphere moisture via soil respiration.Soil salinity also has important effects on soil water movement and spatial-temporal heterogeneity.The extremely dry climate,terrestrial heat and change of upper soil temperature are the fundamental driving forces of water transportation and phreatic water evaporation in the Groundwater-Soil-Plant-Atmosphere Continuum(GSPAC) system.
基金National Key Research and Development Program of China under Grant No.2019YFA0307703the Major Research Plan of the National Natural Science Foundation of China under Grant No.91850201the National Natural Science Foundation of China under Grant No.11974426.
文摘Isolated attosecond pulses with a duration of 88 as are generated in the spectral range of 29–72 eV using double optical gating technique.The gate width is set to be shorter than half the optical cycle to avoid carrier envelop phase stabilization of the 4.2 fs driving laser pulses centered at 800 nm.The attosecond pulse duration is measured with the technique of frequency resolved optical gating for complete reconstruction of attosecond bursts.
基金Singapore MOE Tier Ⅱ grant R143-000-A29-112the National Research Foundation under the Grant of NRF2017NRF-NSFC001-007.
文摘Pore structure of hard carbon has a fundamental influence on the electrochemical properties in sodium-ion batteries(SIBs).Ultra-micropores(<0.5 nm)of hard carbon can function as ionic sieves to reduce the diffusion of slovated Na+but allow the entrance of naked Na^(+) into the pores,which can reduce the interficial contact between the electrolyte and the inner pores without sacrificing the fast diffusion kinetics.Herein,a molten diffusion-carbonization method is proposed to transform the micropores(>1 nm)inside carbon into ultra-micropores(<0.5 nm).Consequently,the designed carbon anode displays an enhanced capacity of 346 mAh g^(−1) at 30 mA g^(−1) with a high ICE value of~80.6%and most of the capacity(~90%)is below 1 V.Moreover,the high-loading electrode(~19 mg cm^(−2))exhibits a good temperature endurance with a high areal capacity of 6.14 mAh cm^(−2) at 25℃ and 5.32 mAh cm^(−2) at −20℃.Based on the in situ X-ray diffraction and ex situ solid-state nuclear magnetic resonance results,the designed ultra-micropores provide the extra Na+storage sites,which mainly contributes to the enhanced capacity.This proposed strategy shows a good potential for the development of high-performance SIBs.
基金supported in part by a University of Rochester Institutional Grant(2011NSG-Huang,to JHH)National Institute of Health(NIH-R01-NS-067435,to JHH)the Hellen Vosberg McCrillus Plummer and Robert Edward Lee Plummer,Jr,Endowment fund from Baylor Scott&White Medical Center(to JHH)。
文摘Despite years of effort,no effective acute phase treatment has been discovered for traumatic brain injury.One impediment to successful drug development is entangled secondary injury pathways.Here we show that protein S,a natural multifunctional protein that regulates coagulation,inflammation,and apoptosis,is able to reduce the extent of multiple secondary injuries in traumatic brain injury,and therefore improve prognosis.Mice subjected to controlled cortical impact were treated acutely(10–15 minutes post-injury)with a single dose of either protein S(1 mg/kg)or vehicle phosphate buffered saline via intravenous injection.At 24 hours post-injury,compared to the non-treated group,the protein S treated group showed substantial improvement of edema and fine motor coordination,as well as mitigation of progressive tissue loss.Immunohistochemistry and western blot targeting caspase-3,B-cell lymphoma 2(Bcl-2)along with terminal deoxynucleotidyl transferase dUTP nick end labeling(TUNEL)assay revealed that apoptosis was suppressed in treated animals.Immunohistochemistry targeting CD11 b showed limited leukocyte infiltration in the protein S-treated group.Moreover,protein S treatment increased the ipsilesional expression of aquaporin-4,which may be the underlying mechanism of its function in reducing edema.These results indicate that immediate intravenous protein S treatment after controlled cortical impact is beneficial to traumatic brain injury prognosis.Animal Use Protocols(AUPs)were approved by the University Committee on Animal Resources(UCAR)of University of Rochester Medical Center(approval No.UCAR-2008-102 R)on November 12,2013.
基金supported by the National Natural Science Foundation of China(51705084)the Natural Science Foundation of Guangdong Province(2018A030313999,2019A1515011602)+6 种基金the Fundamental Research Funds for the Central Universities(N2003032)the Opening Project of Guangdong Provincial Key Laboratory of Technique and Equipment for Macromolecular Advanced ManufacturingSouth China University of Technology(2019kfkt06,2020kfkt05)the Research Grants of the University of Macao(MYRG2019-00028-FST)Guangdong Regular Institutions of Characteristic Innovation Project(2017KTSCX176)Key Laboratory of Robotics and Intelligent Equipment of Guangdong Regular Institutions of Higher Education(2017KSYS009)the National Key Research and Development Program of China(2017YFB1300200,2017YFB1300203)。
文摘This paper proposes a static-output-feedback based robust fuzzy wheelbase preview control algorithm for uncertain active suspensions with time delay and finite frequency constraint.Firstly,a Takagi-Sugeno(T-S)fuzzy augmented model is established to formulate the half-car active suspension system with consideration of time delay,sprung mass variation and wheelbase preview information.Secondly,in view of the resonation between human’s organs and vertical vibrations in the frequency range of 4–8 Hz,a finite frequency control criterion in terms of H∞norm is developed to improve ride comfort.Meanwhile,other mechanical constraints are also considered and satisfied via generalized H2 norm.Thirdly,in order to maintain the feasibility of the controller despite of some state variables are not online-measured,a two stage approach is adopted to derive a static output feedback controller.Finally,numerical simulation results illustrate the excellent performance of the proposed controller.
