S Background Music therapy is a promising complementary intervention for addressing various mental health conditions.Despite evidence of the beneficial effects of music,the acoustic features that make music effective ...S Background Music therapy is a promising complementary intervention for addressing various mental health conditions.Despite evidence of the beneficial effects of music,the acoustic features that make music effective in therapeutic contexts remain elusive.Aims This study aimed to identify and validate distinctive acoustic features of healing music.Methods We constructed a healing music dataset(HMD)based on nominations from related professionals and extracted 370 acoustic features.Healing-distinctive acoustic features were identified as those that were(1)independent from genre within the HMD,(2)significantly different from music pieces in a classical music dataset(CMD)and(3)similar to pieces in a five-element music dataset(FEMD).We validated the identified features by comparing jazz pieces in the HMD with a jazz music dataset(JMD).We also examined the emotional properties of the features in a Chinese affective music system(CAMS).Results The HMD comprised 165 pieces.Among all the acoustic features,74.59%shared commonalities across genres,and 26.22%significantly differed between the HMD classical pieces and the CMD.The equivalence test showed that the HMD and FEMD did not differ significantly in 9.46%of the features.The potential healing-distinctive acoustic features were identified as the standard deviation of the roughness,mean and period entropy of the third coefficient of the mel-frequency cepstral coefficients.In a three-dimensional space defined by these features,HMD's jazz pieces could be distinguished from those of the JMD.These three features could significantly predict both subjective valence and arousal ratings in the CAMS.Conclusions The distinctive acoustic features of healing music that have been identified and validated in this study have implications for the development of artificial intelligence models for identifying therapeutic music,particularly in contexts where access to professional expertise may be limited.This study contributes to the growing body of research exploring the potential of digital technologies for healthcare interventions.展开更多
Objective: This analysis was conducted to clarify risk factors for chemotherapy-induced leukopenia (CIL) in lung cancer. Methods: A retrospective study was conducted on data from 358 patients with lung cancer who rece...Objective: This analysis was conducted to clarify risk factors for chemotherapy-induced leukopenia (CIL) in lung cancer. Methods: A retrospective study was conducted on data from 358 patients with lung cancer who received chemotherapy. Results: Among 358 cases of lung cancer who received chemotherapy, a total of 240 patients experienced CIL, rate was 67%. The demographic data including gender (P = 0.795), age (P = 0.134), presence of selected chronic comorbidities (P = 0.23) were not significantly different in the two groups. The weight loss rate, PS score, sub-normal pre-WBC level, sub-normal pre-PLT level, and the cycle of chemotherapy were significantly different between the groups (P < 0.05). Multivariate analysis revealed that the weight loss rate ≥5% (OR = 0.503), sub-normal pre-WBC level (OR = 11.807), the cycle of chemotherapy ≥3 (OR = 3.100) were main risk factors for CIL in lung cancer. Conclusion: Before treatment, weight loss rate is 5% or higher, chemotherapy has a cycle of 3 or more and sub-normal WBC level is independent risk factor of lung cancer after chemotherapy-induced leucopenia.展开更多
The thermal decomposition process was studied by the TG–DTA analyzer. The results show that the decomposition process of sodium hydroxyethyl sulfonate consisted of three stages: the mass loss for the first, the secon...The thermal decomposition process was studied by the TG–DTA analyzer. The results show that the decomposition process of sodium hydroxyethyl sulfonate consisted of three stages: the mass loss for the first, the second and third stages may be about the groups of CH_3CH_2OH, CH_3CHO and SO_2 volatilized, respectively. The decomposition residuum of three stages was analyzed by FT-IR, and the results of FT-IR agreed with the decomposition process predicted by theoretical weight loss. The specific heat capacity of sodium hydroxyethyl sulfonate was determined by differential scanning calorimetry(DSC). The melting temperature and melting enthalpy were obtained to be 465.41 K and 25.69 kJ·mol^(-1), respectively. The molar specific heat capacity of sodium hydroxyethyl sulfonate was determinated from 310.15 K to 365.15 K and expressed as a function of temperature.展开更多
Plants are amazing chemical factories,and medicinal plants provide a myriad of pharmaceutically active compounds that have been commonly used as traditional medicines for thousands of years.The practice of traditional...Plants are amazing chemical factories,and medicinal plants provide a myriad of pharmaceutically active compounds that have been commonly used as traditional medicines for thousands of years.The practice of traditional medicine in China dates back at least 4,500 years.The Shen Nong Ben Cao Jing("Shen Nong's Herbal Classic"in 770−475 BC)has been considered the oldest list of medicinal plants.Recent rapid economic development has enabled China to invest substantially in science and technology research.In many ethnic groups worldwide,herbal medicines are,in the same way as traditional Chinese medicines,still commonly used today.A wide array of plant-extract health supplements has become increasingly popular in Western societies.Numerous drugs derived from a broad range of plant species have been discoveried,such as taxol and artemisinin and their derivatives.展开更多
Cotton is an irreplaceable economic crop currently domesticated in the human world for its extremely elongated fiber cells specialized in seed epidermis,which makes it of high research and application value.To date,nu...Cotton is an irreplaceable economic crop currently domesticated in the human world for its extremely elongated fiber cells specialized in seed epidermis,which makes it of high research and application value.To date,numerous research on cotton has navigated various aspects,from multi-genome assembly,genome editing,mechanism of fiber development,metabolite biosynthesis,and analysis to genetic breeding.Genomic and 3D genomic studies reveal the origin of cotton species and the spatiotemporal asymmetric chromatin structure in fibers.Mature multiple genome editing systems,such as CRISPR/Cas9,Cas12(Cpf1)and cytidine base editing(CBE),have been widely used in the study of candidate genes affecting fiber development.Based on this,the cotton fiber cell development network has been preliminarily drawn.Among them,the MYB-b HLH-WDR(MBW)transcription factor complex and IAA and BR signaling pathway regulate the initiation;various plant hormones,including ethylene,mediated regulatory network and membrane protein overlap fine-regulate elongation.Multistage transcription factors targeting Ces A 4,7,and 8 specifically dominate the whole process of secondary cell wall thickening.And fluorescently labeled cytoskeletal proteins can observe real-time dynamic changes in fiber development.Furthermore,research on the synthesis of cotton secondary metabolite gossypol,resistance to diseases and insect pests,plant architecture regulation,and seed oil utilization are all conducive to finding more high-quality breeding-related genes and subsequently facilitating the cultivation of better cotton varieties.This review summarizes the paramount research achievements in cotton molecular biology over the last few decades from the above aspects,thereby enabling us to conduct a status review on the current studies of cotton and provide strong theoretical support for the future direction.展开更多
目的探讨3.0 T MRI的定量磁敏感成像(QSM)上中央静脉征(CVS)、铁沉积鉴别诊断多发性硬化(MS)与视神经脊髓炎谱系疾病(NMOSD)患者颅内病灶的价值。方法本研究为回顾性研究。收集2018年7月至2020年12月乐山市人民医院和重庆医科大学附属...目的探讨3.0 T MRI的定量磁敏感成像(QSM)上中央静脉征(CVS)、铁沉积鉴别诊断多发性硬化(MS)与视神经脊髓炎谱系疾病(NMOSD)患者颅内病灶的价值。方法本研究为回顾性研究。收集2018年7月至2020年12月乐山市人民医院和重庆医科大学附属第一医院临床确诊的54例MS患者和49例NMOSD患者。所有患者均接受常规MRI和三维增强T2*加权血管成像(3D-ESWAN),并从3D-ESWAN数据重建滤波相位图和QSM。首先在质子密度(PD)-T2WI筛选MS及NMOSD的颅内病灶,然后在相位图和QSM图上观察病灶位置、CVS以及结节状、环状铁沉积。采用χ^(2)检验比较MS与NMOSD患者颅内病灶位置、CVS、铁沉积的差异。采用受试者操作特征曲线及曲线下面积(AUC)评估CVS、QSM铁沉积鉴别MS和NMOSD的效能。结果 54例MS患者观察到968个颅脑病灶,其中354个病灶有CVS,227个CVS位于侧脑室周围,117个位于深部白质(DWM),10个位于皮层/皮层下;QSM上有372个病灶表现为结节状铁沉积、193个病灶表现为环状铁沉积。48例NMOSD患者中41例观察到247个颅脑病灶,其中4个病灶有CVS,1个位于侧脑室周围,3个位于DWM;QSM上3个病灶有结节状铁沉积。MS与NMOSD患者颅内病灶位于皮层/皮层下、CVS、铁沉积差异有统计学意义(χ^(2)分别为29.33、115.66、258.21,P<0.001)。CVS鉴别MS和NMOSD的AUC为0.941(95%CI 0.887~0.994),灵敏度为96.3%,特异度为91.8%;铁沉积鉴别MS和NMOSD的AUC为0.969(95%CI 0.930~1.000),灵敏度为100%,特异度为93.9%。结论 3.0 T MRI上CVS和铁沉积是MS病灶截然不同于NMOSD病灶的影像学特征,对鉴别二者具有一定的价值。展开更多
The effects of Sm on the microstructure and mechanical properties of Mg-11 Gd-2 Y-0.6 Al alloy were investigated by X-ray diffraction,optical microscopy,scanning electron microscopy,energy dispersive spectrometry and ...The effects of Sm on the microstructure and mechanical properties of Mg-11 Gd-2 Y-0.6 Al alloy were investigated by X-ray diffraction,optical microscopy,scanning electron microscopy,energy dispersive spectrometry and high resolution transmission electron microscopy.Based on the theory of edge—edge matching and electronegativity theory,the mechanism of grain refinement is discussed.The strengthening mechanism is expounded conveniently from fine grain strengthening,coherent strengthening,precipitation strengthening and grain boundary strengthening.The results show that the micro structure of Mg-11 Gd-2 Y-0.6 Al alloy is mainly composed of a-Mg matrix,Mg5 Gd and Mg24Y5 phases.The addition of Sm forms Mg41Sm5 phase in the alloy and refines the alloy.The addition of Sm significantly improves the mechanical properties of the alloy at room and high temperatures.When the addition of Sm is 3 wt%,the tensile strengths of the alloy at room temperature and high temperature(200℃)reach the maximum value 292 and 321 MPa,respectively.The fracture mode of the alloy at different temperatures is mainly brittle fracture and intercrystalline fracture.展开更多
Sesquiterpenoids are a class of 15-carbon secondary metabolites that play diverse roles in plant adaptation to environment.Cotton plants accumulate a large amount of sesquiterpene aldehydes(including gossypol)as phyto...Sesquiterpenoids are a class of 15-carbon secondary metabolites that play diverse roles in plant adaptation to environment.Cotton plants accumulate a large amount of sesquiterpene aldehydes(including gossypol)as phytoalexins against pathogens and herbivores.They are stored in pigment glands of aerial organs and in epidermal layers of roots.Several enzymes of gossypol biosynthesis pathway have been characterized,including 3-hydroxy-3-methylglutaryl coenzyme A reductase(HMGR)and farnesyl diphosphate synthase(FPS)that catalyze the formation of the precursor farnesyl diphosphate(FPP),(+)-δ-cadinene synthase(CDN)which is the first enzyme committed to gossypol biosynthesis,and the downstream enzymes of CYP706B1 and methyltransferase.Expressions of these genes are tightly regulated during cotton plants development and induced by jasmonate and fungi elicitors.The transcription factor Ga WRKY1 has been shown to be involved in gossypol pathway regulation.Recent development of new genomic platforms and methods and releases of diploid and tetraploid cotton genome sequences will greatly facilitate the elucidation of gossypol biosynthetic pathway and its regulation.展开更多
Trimercaptotriazine-functionalized polystyrene chelating resin was prepared and employed for the adsorption of Ag(I)from aqueous solution.The adsorbent was characterized according to the following techniques:Fourier t...Trimercaptotriazine-functionalized polystyrene chelating resin was prepared and employed for the adsorption of Ag(I)from aqueous solution.The adsorbent was characterized according to the following techniques:Fourier transform infrared spectroscopy,elemental analysis,scanning electron microscopy and the Brunauer-Emmet-Teller method.The effects of initial Ag(I)concentration,contact time,solution pH and coexisting ions on the adsorption capacity of Ag(I)were systematically investigated.The maximum adsorption capacity of Ag(I)was up to 187.1 mg/g resin at pH 0.0 and room temperature.The kinetic experiments indicated that the adsorption rate of Ag(I)onto the chelating resin was quite fast in the first 60 min and reached adsorption equilibrium after 360min.The adsorption process can be well described by the pseudo second-order kinetic model and the equilibrium adsorption isotherm was closely fitted by the Langmuir model.Moreover,the chelating resin could selectively adsorb more Ag(I)ions than other heavy metal ions including:Cu(II),Zn(II),Ni(II),Pb(II)and Cr(III)during competitive adsorption in the binary metal species systems,which indicated that it was a highly selective adsorbent of Ag(I)from aqueous solution.展开更多
The green mirid bug Apolygus lucorum is an agricultural pest that is known to cause damage to more than 150 plant species.Here,we report the transcriptomes of A.lucorum at three different developmental stages(the seco...The green mirid bug Apolygus lucorum is an agricultural pest that is known to cause damage to more than 150 plant species.Here,we report the transcriptomes of A.lucorum at three different developmental stages(the second and fifth instar nymphs and adults).A total of 98,236 unigenes with an average length of l,335 nt was obtained,of which 50,640 were annotated,including those encoding digestive enzymes and cytochrome P450 s.Comparisons with cotton bollworm and cotton aphid transcriptomes revealed distinct features of A.lucorum as a mesophyll feeder.The gene expression dynamics varied during development from young nymphs to adults.The high-quality transcriptome data and the gene expression dynamics reported here provide valuable data for a more comprehensive understanding of the physiology and development of mirid bugs,and for mining targets for their control.展开更多
FeCe nanocomposite catalysts with different iron contents were synthesized by a facile co-precipitation method.The as-prepared materials were characterized by various techniques including powder X-ray diffraction(XRD)...FeCe nanocomposite catalysts with different iron contents were synthesized by a facile co-precipitation method.The as-prepared materials were characterized by various techniques including powder X-ray diffraction(XRD),N2 adsorption/desorption and high-resolution transmission electron microscopy(HRTEM).Catalyst with the highest iron content(90 FeCe) shows the best activity for the hydrogen generation via ammonia decomposition.83% NH3 conversion is achieved at 550℃ and nearly full conversion of NH3 is realized at 600℃ with a GHSV of 24000 cm3/(gcat·h).The large content and small size crystal particles of iron species are responsible for the good catalytic performance.Temperatureprogrammed reduction by hydrogen(H2-TPR) was performed to investigate the interaction between cerium and iron species.It is found that slight cerium can exert strong interaction with iron compound thus effectively prevent the self-aggregation of active iron species,so as to improve the catalytic activity for ammonia decomposition.展开更多
Modern agricultural bio-technologies have significantly increased the efficiency and quality of crop production and contributed to the improvement of people's life in the world.Widespread utilization of fertilizer...Modern agricultural bio-technologies have significantly increased the efficiency and quality of crop production and contributed to the improvement of people's life in the world.Widespread utilization of fertilizers,herbicides,fungicides,pesticides,antibiotics,and plant growth regulators has been instrumental in securing crop yields to feed over seven billions of human beings in the earth.However,during the recent half century,extensive uses of pesticides and other chemicals,which traditionally target the essential physiological pathways of pathogenic microbes and pests,have proverbial,negative impacts on the environmental展开更多
Human history of domestication of wild plants as food source has witnessed continuous improvement in nutritional qualities of plant products.However,some nutritional traits were lost during agricultural breeding(Tiema...Human history of domestication of wild plants as food source has witnessed continuous improvement in nutritional qualities of plant products.However,some nutritional traits were lost during agricultural breeding(Tieman et al.,2017),and some are absent in certain wild ancestors and could展开更多
Metabolism is the basic activity of life.Two international conferences,including the 4th International Conference on Plant Metabolism(ICPM2017,http://www.cspb.org.cn/2017/icpm.asp),and the 13th International Meeting o...Metabolism is the basic activity of life.Two international conferences,including the 4th International Conference on Plant Metabolism(ICPM2017,http://www.cspb.org.cn/2017/icpm.asp),and the 13th International Meeting on Biosynthesis,Function and Synthetic Biology of Isoprenoids(TERPNET2017,http://www.cspb.org.cn/2017/terpnet.asp)were concurrently convened side by side in Dalian from July 16 to 20,2017.The two conferences were scheduled with independent programs to keep their traditional style,but also arranged展开更多
The triennial International Conference on Plant Cell Wall Biology has been held 5 times since it was initiated in the United States.PCWB2017 for the first time is organized in China.The conference was attended with mo...The triennial International Conference on Plant Cell Wall Biology has been held 5 times since it was initiated in the United States.PCWB2017 for the first time is organized in China.The conference was attended with more than 220 participants and featured with oral and poster presentations,reflecting the contemporary status of plant cell wall studies.展开更多
基金supported by the National Natural Science Foundation of China(62101324)the Shanghai Sailing Program(20YF1442000)+2 种基金the Academic Leader of the Health Discipline of Shanghai Municipal Health Commission(2022XD025)the Qihang Program of Shanghai Mental Health Center(2020-QH-01)the Hospital Program of Shanghai Mental Health Center(2020-YJ01)。
文摘S Background Music therapy is a promising complementary intervention for addressing various mental health conditions.Despite evidence of the beneficial effects of music,the acoustic features that make music effective in therapeutic contexts remain elusive.Aims This study aimed to identify and validate distinctive acoustic features of healing music.Methods We constructed a healing music dataset(HMD)based on nominations from related professionals and extracted 370 acoustic features.Healing-distinctive acoustic features were identified as those that were(1)independent from genre within the HMD,(2)significantly different from music pieces in a classical music dataset(CMD)and(3)similar to pieces in a five-element music dataset(FEMD).We validated the identified features by comparing jazz pieces in the HMD with a jazz music dataset(JMD).We also examined the emotional properties of the features in a Chinese affective music system(CAMS).Results The HMD comprised 165 pieces.Among all the acoustic features,74.59%shared commonalities across genres,and 26.22%significantly differed between the HMD classical pieces and the CMD.The equivalence test showed that the HMD and FEMD did not differ significantly in 9.46%of the features.The potential healing-distinctive acoustic features were identified as the standard deviation of the roughness,mean and period entropy of the third coefficient of the mel-frequency cepstral coefficients.In a three-dimensional space defined by these features,HMD's jazz pieces could be distinguished from those of the JMD.These three features could significantly predict both subjective valence and arousal ratings in the CAMS.Conclusions The distinctive acoustic features of healing music that have been identified and validated in this study have implications for the development of artificial intelligence models for identifying therapeutic music,particularly in contexts where access to professional expertise may be limited.This study contributes to the growing body of research exploring the potential of digital technologies for healthcare interventions.
文摘Objective: This analysis was conducted to clarify risk factors for chemotherapy-induced leukopenia (CIL) in lung cancer. Methods: A retrospective study was conducted on data from 358 patients with lung cancer who received chemotherapy. Results: Among 358 cases of lung cancer who received chemotherapy, a total of 240 patients experienced CIL, rate was 67%. The demographic data including gender (P = 0.795), age (P = 0.134), presence of selected chronic comorbidities (P = 0.23) were not significantly different in the two groups. The weight loss rate, PS score, sub-normal pre-WBC level, sub-normal pre-PLT level, and the cycle of chemotherapy were significantly different between the groups (P < 0.05). Multivariate analysis revealed that the weight loss rate ≥5% (OR = 0.503), sub-normal pre-WBC level (OR = 11.807), the cycle of chemotherapy ≥3 (OR = 3.100) were main risk factors for CIL in lung cancer. Conclusion: Before treatment, weight loss rate is 5% or higher, chemotherapy has a cycle of 3 or more and sub-normal WBC level is independent risk factor of lung cancer after chemotherapy-induced leucopenia.
文摘The thermal decomposition process was studied by the TG–DTA analyzer. The results show that the decomposition process of sodium hydroxyethyl sulfonate consisted of three stages: the mass loss for the first, the second and third stages may be about the groups of CH_3CH_2OH, CH_3CHO and SO_2 volatilized, respectively. The decomposition residuum of three stages was analyzed by FT-IR, and the results of FT-IR agreed with the decomposition process predicted by theoretical weight loss. The specific heat capacity of sodium hydroxyethyl sulfonate was determined by differential scanning calorimetry(DSC). The melting temperature and melting enthalpy were obtained to be 465.41 K and 25.69 kJ·mol^(-1), respectively. The molar specific heat capacity of sodium hydroxyethyl sulfonate was determinated from 310.15 K to 365.15 K and expressed as a function of temperature.
文摘Plants are amazing chemical factories,and medicinal plants provide a myriad of pharmaceutically active compounds that have been commonly used as traditional medicines for thousands of years.The practice of traditional medicine in China dates back at least 4,500 years.The Shen Nong Ben Cao Jing("Shen Nong's Herbal Classic"in 770−475 BC)has been considered the oldest list of medicinal plants.Recent rapid economic development has enabled China to invest substantially in science and technology research.In many ethnic groups worldwide,herbal medicines are,in the same way as traditional Chinese medicines,still commonly used today.A wide array of plant-extract health supplements has become increasingly popular in Western societies.Numerous drugs derived from a broad range of plant species have been discoveried,such as taxol and artemisinin and their derivatives.
基金the National Natural Science Foundation of China(32200286)the China Postdoctoral Science Foundation(2022TQ0240,2022M722470)。
文摘Cotton is an irreplaceable economic crop currently domesticated in the human world for its extremely elongated fiber cells specialized in seed epidermis,which makes it of high research and application value.To date,numerous research on cotton has navigated various aspects,from multi-genome assembly,genome editing,mechanism of fiber development,metabolite biosynthesis,and analysis to genetic breeding.Genomic and 3D genomic studies reveal the origin of cotton species and the spatiotemporal asymmetric chromatin structure in fibers.Mature multiple genome editing systems,such as CRISPR/Cas9,Cas12(Cpf1)and cytidine base editing(CBE),have been widely used in the study of candidate genes affecting fiber development.Based on this,the cotton fiber cell development network has been preliminarily drawn.Among them,the MYB-b HLH-WDR(MBW)transcription factor complex and IAA and BR signaling pathway regulate the initiation;various plant hormones,including ethylene,mediated regulatory network and membrane protein overlap fine-regulate elongation.Multistage transcription factors targeting Ces A 4,7,and 8 specifically dominate the whole process of secondary cell wall thickening.And fluorescently labeled cytoskeletal proteins can observe real-time dynamic changes in fiber development.Furthermore,research on the synthesis of cotton secondary metabolite gossypol,resistance to diseases and insect pests,plant architecture regulation,and seed oil utilization are all conducive to finding more high-quality breeding-related genes and subsequently facilitating the cultivation of better cotton varieties.This review summarizes the paramount research achievements in cotton molecular biology over the last few decades from the above aspects,thereby enabling us to conduct a status review on the current studies of cotton and provide strong theoretical support for the future direction.
文摘目的探讨3.0 T MRI的定量磁敏感成像(QSM)上中央静脉征(CVS)、铁沉积鉴别诊断多发性硬化(MS)与视神经脊髓炎谱系疾病(NMOSD)患者颅内病灶的价值。方法本研究为回顾性研究。收集2018年7月至2020年12月乐山市人民医院和重庆医科大学附属第一医院临床确诊的54例MS患者和49例NMOSD患者。所有患者均接受常规MRI和三维增强T2*加权血管成像(3D-ESWAN),并从3D-ESWAN数据重建滤波相位图和QSM。首先在质子密度(PD)-T2WI筛选MS及NMOSD的颅内病灶,然后在相位图和QSM图上观察病灶位置、CVS以及结节状、环状铁沉积。采用χ^(2)检验比较MS与NMOSD患者颅内病灶位置、CVS、铁沉积的差异。采用受试者操作特征曲线及曲线下面积(AUC)评估CVS、QSM铁沉积鉴别MS和NMOSD的效能。结果 54例MS患者观察到968个颅脑病灶,其中354个病灶有CVS,227个CVS位于侧脑室周围,117个位于深部白质(DWM),10个位于皮层/皮层下;QSM上有372个病灶表现为结节状铁沉积、193个病灶表现为环状铁沉积。48例NMOSD患者中41例观察到247个颅脑病灶,其中4个病灶有CVS,1个位于侧脑室周围,3个位于DWM;QSM上3个病灶有结节状铁沉积。MS与NMOSD患者颅内病灶位于皮层/皮层下、CVS、铁沉积差异有统计学意义(χ^(2)分别为29.33、115.66、258.21,P<0.001)。CVS鉴别MS和NMOSD的AUC为0.941(95%CI 0.887~0.994),灵敏度为96.3%,特异度为91.8%;铁沉积鉴别MS和NMOSD的AUC为0.969(95%CI 0.930~1.000),灵敏度为100%,特异度为93.9%。结论 3.0 T MRI上CVS和铁沉积是MS病灶截然不同于NMOSD病灶的影像学特征,对鉴别二者具有一定的价值。
基金Project supported by the National Natural Science Foundation of China(51571084 and 51171059)Project of Scientific And Technological Research In Henan Province(152102210072)
文摘The effects of Sm on the microstructure and mechanical properties of Mg-11 Gd-2 Y-0.6 Al alloy were investigated by X-ray diffraction,optical microscopy,scanning electron microscopy,energy dispersive spectrometry and high resolution transmission electron microscopy.Based on the theory of edge—edge matching and electronegativity theory,the mechanism of grain refinement is discussed.The strengthening mechanism is expounded conveniently from fine grain strengthening,coherent strengthening,precipitation strengthening and grain boundary strengthening.The results show that the micro structure of Mg-11 Gd-2 Y-0.6 Al alloy is mainly composed of a-Mg matrix,Mg5 Gd and Mg24Y5 phases.The addition of Sm forms Mg41Sm5 phase in the alloy and refines the alloy.The addition of Sm significantly improves the mechanical properties of the alloy at room and high temperatures.When the addition of Sm is 3 wt%,the tensile strengths of the alloy at room temperature and high temperature(200℃)reach the maximum value 292 and 321 MPa,respectively.The fracture mode of the alloy at different temperatures is mainly brittle fracture and intercrystalline fracture.
基金This work was supported by National Natural Science Foundation of China （31200615, 31600238）, Postgraduate Research and Innovation Project of Hunan Province （CX2014B302）, National Key Laboratory Cultivation Base Construction Project （15KFXM09）, the National Science-Technology Support Plan Projects of China （2012BAI29B04）, The talent introduction Science Foundation of Hunan Agricultural University （13YJ09）, and the Natural Science Foundation of Hunan Province （2016JJ4040）.
文摘在动物农业和药的抗菌素的 overuse 引起了一系列潜在的威胁到公共健康。Macleaya cordata 是从 Papaveraceae 家庭的药用的植物种，提供为抗菌剂的制造的一个安全资源为家畜喂添加剂。从 M. 的活跃成分 ? cordata 被知道包括 benzylisoquinoline 碱(偏爱) 象 sanguinarine (圣) 和 chelerythrine (CHE ) 那样的 ?，而是他们的新陈代谢的小径还得在这非模型植物被学习。在 M. 的圣和 CHE 的活跃生合成 ? cordata 被喂 <sup>13</sup 首先检验并且证实 >标记 C 的酷氨酸。为了增加，推进卓见，我们 de novo 定序 M 的整个染色体。cordata，第一从 Papaveraceae 家庭被定序。M.? 盖住 378 Mb 的 cordata 染色体与 43.5%being 编码 22,328 预言的编码蛋白质的基因 transposable 元素。作为基础 eudicot 的一个成员， M.? cordata 染色体缺乏 ? 发生在几乎所有 eudicots 的 paleohexaploidy 事件。从 genomics 数据， 16 的一个完全的集合 ? 新陈代谢 ? 为圣和 CHE 生合成的基因被检索，并且 14 项他们的生物化学的活动被验证。这些 genomics 和新陈代谢的数据在 M. 显示出保存 BIA 新陈代谢的小径 ? cordata 并且由庄稼改进或微生物引起的小径重建为圣和 CHE 的未来生产提供知识基础。
基金the State Key Basic Research Program of China (2013CB127000)the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB11030300)+1 种基金the National Natural Science Foundation of China (31300255)the Special Fund for Shanghai Landscaping Administration Bureau Program (G142425, F112418).
文摘Sesquiterpenoids are a class of 15-carbon secondary metabolites that play diverse roles in plant adaptation to environment.Cotton plants accumulate a large amount of sesquiterpene aldehydes(including gossypol)as phytoalexins against pathogens and herbivores.They are stored in pigment glands of aerial organs and in epidermal layers of roots.Several enzymes of gossypol biosynthesis pathway have been characterized,including 3-hydroxy-3-methylglutaryl coenzyme A reductase(HMGR)and farnesyl diphosphate synthase(FPS)that catalyze the formation of the precursor farnesyl diphosphate(FPP),(+)-δ-cadinene synthase(CDN)which is the first enzyme committed to gossypol biosynthesis,and the downstream enzymes of CYP706B1 and methyltransferase.Expressions of these genes are tightly regulated during cotton plants development and induced by jasmonate and fungi elicitors.The transcription factor Ga WRKY1 has been shown to be involved in gossypol pathway regulation.Recent development of new genomic platforms and methods and releases of diploid and tetraploid cotton genome sequences will greatly facilitate the elucidation of gossypol biosynthetic pathway and its regulation.
基金supported by the Chinese Academy of Science and Technology Project in Support of Gansu (No.XBLZ-2011-013)
文摘Trimercaptotriazine-functionalized polystyrene chelating resin was prepared and employed for the adsorption of Ag(I)from aqueous solution.The adsorbent was characterized according to the following techniques:Fourier transform infrared spectroscopy,elemental analysis,scanning electron microscopy and the Brunauer-Emmet-Teller method.The effects of initial Ag(I)concentration,contact time,solution pH and coexisting ions on the adsorption capacity of Ag(I)were systematically investigated.The maximum adsorption capacity of Ag(I)was up to 187.1 mg/g resin at pH 0.0 and room temperature.The kinetic experiments indicated that the adsorption rate of Ag(I)onto the chelating resin was quite fast in the first 60 min and reached adsorption equilibrium after 360min.The adsorption process can be well described by the pseudo second-order kinetic model and the equilibrium adsorption isotherm was closely fitted by the Langmuir model.Moreover,the chelating resin could selectively adsorb more Ag(I)ions than other heavy metal ions including:Cu(II),Zn(II),Ni(II),Pb(II)and Cr(III)during competitive adsorption in the binary metal species systems,which indicated that it was a highly selective adsorbent of Ag(I)from aqueous solution.
基金supported by the Strategic Priority Research Program of Chinese Academy of Sciences(XDB11030000)the Ministry of Agriculture of China(2014ZX08009001-009)
文摘The green mirid bug Apolygus lucorum is an agricultural pest that is known to cause damage to more than 150 plant species.Here,we report the transcriptomes of A.lucorum at three different developmental stages(the second and fifth instar nymphs and adults).A total of 98,236 unigenes with an average length of l,335 nt was obtained,of which 50,640 were annotated,including those encoding digestive enzymes and cytochrome P450 s.Comparisons with cotton bollworm and cotton aphid transcriptomes revealed distinct features of A.lucorum as a mesophyll feeder.The gene expression dynamics varied during development from young nymphs to adults.The high-quality transcriptome data and the gene expression dynamics reported here provide valuable data for a more comprehensive understanding of the physiology and development of mirid bugs,and for mining targets for their control.
基金Project supported by the Natural Science Foundation of Jiangsu Province (BK20170232,BK20170238)National Natural Science Foundation of China (51908256)。
文摘FeCe nanocomposite catalysts with different iron contents were synthesized by a facile co-precipitation method.The as-prepared materials were characterized by various techniques including powder X-ray diffraction(XRD),N2 adsorption/desorption and high-resolution transmission electron microscopy(HRTEM).Catalyst with the highest iron content(90 FeCe) shows the best activity for the hydrogen generation via ammonia decomposition.83% NH3 conversion is achieved at 550℃ and nearly full conversion of NH3 is realized at 600℃ with a GHSV of 24000 cm3/(gcat·h).The large content and small size crystal particles of iron species are responsible for the good catalytic performance.Temperatureprogrammed reduction by hydrogen(H2-TPR) was performed to investigate the interaction between cerium and iron species.It is found that slight cerium can exert strong interaction with iron compound thus effectively prevent the self-aggregation of active iron species,so as to improve the catalytic activity for ammonia decomposition.
文摘Modern agricultural bio-technologies have significantly increased the efficiency and quality of crop production and contributed to the improvement of people's life in the world.Widespread utilization of fertilizers,herbicides,fungicides,pesticides,antibiotics,and plant growth regulators has been instrumental in securing crop yields to feed over seven billions of human beings in the earth.However,during the recent half century,extensive uses of pesticides and other chemicals,which traditionally target the essential physiological pathways of pathogenic microbes and pests,have proverbial,negative impacts on the environmental
文摘Human history of domestication of wild plants as food source has witnessed continuous improvement in nutritional qualities of plant products.However,some nutritional traits were lost during agricultural breeding(Tieman et al.,2017),and some are absent in certain wild ancestors and could
文摘Metabolism is the basic activity of life.Two international conferences,including the 4th International Conference on Plant Metabolism(ICPM2017,http://www.cspb.org.cn/2017/icpm.asp),and the 13th International Meeting on Biosynthesis,Function and Synthetic Biology of Isoprenoids(TERPNET2017,http://www.cspb.org.cn/2017/terpnet.asp)were concurrently convened side by side in Dalian from July 16 to 20,2017.The two conferences were scheduled with independent programs to keep their traditional style,but also arranged
文摘The triennial International Conference on Plant Cell Wall Biology has been held 5 times since it was initiated in the United States.PCWB2017 for the first time is organized in China.The conference was attended with more than 220 participants and featured with oral and poster presentations,reflecting the contemporary status of plant cell wall studies.
