We investigate the performance of multiple relays cooperative go back n automatic repeat request(MRC-GBn-ARQ) protocol with limited retransmission. An N +2-state Markov transition model is constructed for analyzing ar...We investigate the performance of multiple relays cooperative go back n automatic repeat request(MRC-GBn-ARQ) protocol with limited retransmission. An N +2-state Markov transition model is constructed for analyzing arbitrary packet transmission process with limited retransmission. Then the system's steadystate distribution is derived by using the Kolmogorov equations.Further, the mean packet transmission delay and startup delay are obtained respectively; the channel utilization is derived based on discrete-time Geom/G/1 queue model with startup. Also, we get the energy efficiency of the MRC-GBn-ARQ based on energy analytical model. Especially, the presented models are contrary to the classical ARQ protocols of always allowing infinite retransmission, and our analysis of the MRC-GBn-ARQ protocol with limited retransmission provides theoretical results for reducing the system's delay and energy consumption. Finally, analysis is validated through some numerical simulations.展开更多
Based on the survey data about clam breeding farmers in Hongdao Town in August 2011,this paper analyzes the production and operation of typical clam breeding pattern,and estimates the costs and benefits. Through the a...Based on the survey data about clam breeding farmers in Hongdao Town in August 2011,this paper analyzes the production and operation of typical clam breeding pattern,and estimates the costs and benefits. Through the analysis of operation conditions and economic conditions of Hongdao clam breeding,this paper aims to explore a more reasonable and effective breeding pattern so as to reduce breeding costs and market risks,and increase breeding farmers' income.展开更多
Proanthocyanidins naturally occur in various fruits,some vegetables and beverages.Increasing evidence has shown that dietary intake of proanthocyanidins is a promising alternative to tumor chemoprevention or chemother...Proanthocyanidins naturally occur in various fruits,some vegetables and beverages.Increasing evidence has shown that dietary intake of proanthocyanidins is a promising alternative to tumor chemoprevention or chemotherapy.Grape seeds are the most abundant source of proanthocyanidins,and grape seed proanthocyanidins(GSPs)show an anticancer effect on hepatocellular carcinoma(HCC),which accounts for approximately 85-90%of all primary liver malignancies.Although an increasing number of studies have investigated the effects of GSPs on HCC and the associated mechanisms,the precise mechanism of GSP therapy in HCC remains unclear.This study aimed to understand the cytotoxic effect of GSPs on HepG2 cells by investigating morphology and growth inhibition.Cell proliferation and apoptosis were estimated by an MTT assay and flow cytometry,and the protein expression of HepG2 cells was determined through Western blotting.The results indicated that GSPs could markedly inhibit HepG2 liver cancer cells and induce apoptosis,with the effects varying by dose and treatment time.Furthermore,GSPs inhibited the phosphorylation of extracellular regulated protein kinases(ERK),c-Jun NH2-terminal kinase(JNK),p38 mitogen-activated protein kinase(p38 MAPK),IκBα,pyruvate dehydrogenase kinase 1(PDK1),glycogen synthase kinase-3 beta(GSK3β)and protein kinase B(AKT),which accounted for the inactivation of mitogen-activated protein kinase/AKT(MAPK/AKT)pathways.These results indicate that GSPs are a potential source of natural chemopreventive agents for the treatment of HCC.展开更多
基金supported by the National Natural Science Foundation of China(61167005)
文摘We investigate the performance of multiple relays cooperative go back n automatic repeat request(MRC-GBn-ARQ) protocol with limited retransmission. An N +2-state Markov transition model is constructed for analyzing arbitrary packet transmission process with limited retransmission. Then the system's steadystate distribution is derived by using the Kolmogorov equations.Further, the mean packet transmission delay and startup delay are obtained respectively; the channel utilization is derived based on discrete-time Geom/G/1 queue model with startup. Also, we get the energy efficiency of the MRC-GBn-ARQ based on energy analytical model. Especially, the presented models are contrary to the classical ARQ protocols of always allowing infinite retransmission, and our analysis of the MRC-GBn-ARQ protocol with limited retransmission provides theoretical results for reducing the system's delay and energy consumption. Finally, analysis is validated through some numerical simulations.
基金Supported by Special Funding for the Construction of National Modern Agricultural Technology System-Shellfish System(Subitem of Industrial Economy CARS-48-09B)General Project of Zhejiang Provincial Education Department(Y201430449)
文摘Based on the survey data about clam breeding farmers in Hongdao Town in August 2011,this paper analyzes the production and operation of typical clam breeding pattern,and estimates the costs and benefits. Through the analysis of operation conditions and economic conditions of Hongdao clam breeding,this paper aims to explore a more reasonable and effective breeding pattern so as to reduce breeding costs and market risks,and increase breeding farmers' income.
基金provided by the Research Cooperation Fund Project of Agricultural University of China and Xinjiang Agricultural University in 2016(grant number:2017TC010).
文摘Proanthocyanidins naturally occur in various fruits,some vegetables and beverages.Increasing evidence has shown that dietary intake of proanthocyanidins is a promising alternative to tumor chemoprevention or chemotherapy.Grape seeds are the most abundant source of proanthocyanidins,and grape seed proanthocyanidins(GSPs)show an anticancer effect on hepatocellular carcinoma(HCC),which accounts for approximately 85-90%of all primary liver malignancies.Although an increasing number of studies have investigated the effects of GSPs on HCC and the associated mechanisms,the precise mechanism of GSP therapy in HCC remains unclear.This study aimed to understand the cytotoxic effect of GSPs on HepG2 cells by investigating morphology and growth inhibition.Cell proliferation and apoptosis were estimated by an MTT assay and flow cytometry,and the protein expression of HepG2 cells was determined through Western blotting.The results indicated that GSPs could markedly inhibit HepG2 liver cancer cells and induce apoptosis,with the effects varying by dose and treatment time.Furthermore,GSPs inhibited the phosphorylation of extracellular regulated protein kinases(ERK),c-Jun NH2-terminal kinase(JNK),p38 mitogen-activated protein kinase(p38 MAPK),IκBα,pyruvate dehydrogenase kinase 1(PDK1),glycogen synthase kinase-3 beta(GSK3β)and protein kinase B(AKT),which accounted for the inactivation of mitogen-activated protein kinase/AKT(MAPK/AKT)pathways.These results indicate that GSPs are a potential source of natural chemopreventive agents for the treatment of HCC.
