Dear Editor,This letter presents a novel dynamic vision enabled contactless cross-domain fault diagnosis method with neuromorphic computing.The event-based camera is adopted to capture the machine vibration states in ...Dear Editor,This letter presents a novel dynamic vision enabled contactless cross-domain fault diagnosis method with neuromorphic computing.The event-based camera is adopted to capture the machine vibration states in the perspective of vision.展开更多
This study examines the effects of digital financial inclusion on non-farm employment of rural labor and the mediating mechanism of innovation and entrepreneurship activity using China Family Panel Studies(CFPS)and th...This study examines the effects of digital financial inclusion on non-farm employment of rural labor and the mediating mechanism of innovation and entrepreneurship activity using China Family Panel Studies(CFPS)and the provincial index of digital financial inclusion.Through the empirical test of the Probit model and mediation effect model,we found that:firstly,digital financial inclusion can promote non-farm employment of rural labor,with the level of digitalization having the most significant impact;secondly,by encouraging innovation and entrepreneurial activity,digital financial inclusion can promote non-farm employment of rural labor;thirdly,the driving effect of digital financial inclusion on non-farm employment of rural labor is more pronounced among the unmarried,eastern region,and male labor.Therefore,we should improve the construction of rural digital infrastructure and accelerate the development of inclusive rural finance to promote more diversified non-farm employment options for“disadvantaged groups”;encourage and support innovation at the government level,and create a favorable atmosphere for innovation and entrepreneurship.Simultaneously,farmers’digital literacy and financial knowledge should be improved so that more can adopt and take advantage of digital financial inclusion.展开更多
Diffuse large B-cell lymphoma(DLBCL)is the most common non-Hodgkin’s lymphoma(NHL)and has high heterogeneity.Approximately 30%–50%of patients develop relapsed/refractory(R/R)disease,which remains a major cause of mo...Diffuse large B-cell lymphoma(DLBCL)is the most common non-Hodgkin’s lymphoma(NHL)and has high heterogeneity.Approximately 30%–50%of patients develop relapsed/refractory(R/R)disease,which remains a major cause of mortality1-3.In recent years,a variety of novel therapies have emerged,including bispecific T-cell engagers(BiTEs),antibody–drug conjugates(ADCs),chimeric antigen receptor T cells(CAR-T),and selective BTK inhibitors,which have provided effective treatment strategies for patients with DLBCL1,4.Recently,the 58th Annual Meeting of the American Society of Clinical Oncology(ASCO)was held in Chicago,presenting cutting-edge studies in DLBCL.Here,we discuss a selection of interesting data on this topic.展开更多
Quasi-two-dimensional perovskite light-emitting diodes (quasi-2D PeLEDs) are emerging as high-potential candidates for new generation of wide-color gamut displays due to their simple, low-cost solution process, and hi...Quasi-two-dimensional perovskite light-emitting diodes (quasi-2D PeLEDs) are emerging as high-potential candidates for new generation of wide-color gamut displays due to their simple, low-cost solution process, and high color purity. However, the luminescence performance of quasi-2D perovskite films is severely limited by dispersed phase distribution and excessive defect density, which are caused by excessive diffusion of nucleation sites during the perovskite growth stage. Here, the benzylphosphonic acid (BPA) molecule, owing to its strong P-O-Pb bond energy sites and strong electronegativity to PEA+, can aggregate lead-halide octahedron to grow high-dimensional phases, avoiding scattered low-dimensional phases (n = 1). The continuous gradient phase distribution will be beneficial to smooth carrier injection and effectively suppress the leakage current in PeLEDs. Meanwhile, the introduction of phosphonic acid groups will fill the vacancies of Pb ions and reduce non-radiative recombination. As a result, the maximum external quantum efficiency (EQE) of PeLEDs can be increased from 8% to 20.6% with a 514 nm light emission and a 21 nm full-width half maximum, and the device lifetime (T 50) is nearly 6-fold of the pristine sample. In addition, this strategy is also suitable for other wavelength. For example, in blue light, performance improvement is also realized that the maximum EQE of 8% and the luminance increased from 1045 to 5264 cd/m2. These results provide a feasible strategy to regulate the phase distribution and passivate the defects of quasi-2D perovskites.展开更多
Purpose Lymphoma has become a major threat to human health.Fortunately,the diagnosis and treatment of lymphoma have developed rapidly,and research progress has emerged in an endless stream,with new drugs emerging one ...Purpose Lymphoma has become a major threat to human health.Fortunately,the diagnosis and treatment of lymphoma have developed rapidly,and research progress has emerged in an endless stream,with new drugs emerging one after another.These results are constantly rewriting guidelines changing clinical practice,need to be popularized and applied more widely.Methods This guideline has integrated consensuses reached by the Lymphoma Committee of China Anti-Cancer Association(CACA),based on China’s practice,tracking previous results of the most advanced clinical researches,absorbing the latest clinical evidence,and referring to domestic and international lymphoma guidelines.Results This holistic integrative guideline of lymphoma introduces the latest progress in the diagnosis and treatment of different subtypes of lymphoma,guide the clinical application of new drugs,standardized and precise management for lymphoma patients.Conclusions CACA guidelines for holistic integrative management of lymphoma(version 2022)enhance standardization and precision of the management for lymphoma patients in China.展开更多
Due to its excellent electrical and optical features,silicon(Si)is highly attractive for photodetector applications.The design and fabrication of low-dimensional semiconductor/Si hybrid heterostructures provide a grea...Due to its excellent electrical and optical features,silicon(Si)is highly attractive for photodetector applications.The design and fabrication of low-dimensional semiconductor/Si hybrid heterostructures provide a great platform for fabricating high-performance photodetectors,thereby overcoming the inherent limitations of Si.This review focuses on state-of-the-art Si heterostructure-based photodetectors.It starts with the introduction of three different device configurations,that is,photoconductors,photodiodes,and phototransistors.Their working mechanisms and relative pros and cons are introduced,and the figures of merit of photodetectors are summarized.Then,we discuss the device physics/design,photodetection performance,and optimization strategies for Si-based photodetectors.Finally,future challenges in the photodetector applications of Si-based hybrid heterostructures are discussed.展开更多
基金supported in part by the National Key R&D Program of China (2022YFB3402100)the National Science Fund for Distinguished Young Scholars of China (52025056)。
文摘Dear Editor,This letter presents a novel dynamic vision enabled contactless cross-domain fault diagnosis method with neuromorphic computing.The event-based camera is adopted to capture the machine vibration states in the perspective of vision.
基金Ministry of Education Humanities and Social Science Foundation Youth Project“Micro-Quantification,Action Mechanism and Impact Research on Financialization of Entity Enterprises”[Grant number.19YJC790106]National Social Science Fund“Mechanism Analysis and Optimization Path Research of Digital Finance Supporting the Improvement of development efficiency of SMEs”[Grant number.21BJY047]+1 种基金Science and Technology Research Program of Chongqing Municipal Education Commission of China:“Research on the Mechanism and Path of Green Finance to Promote Poverty Alleviation in Poor areas in Western China”[Grant number.KJQN201900550]Science and Technology Research Program of Chongqing Municipal Education Commission of China:“Research on Financial Efficiency and High-quality Innovation Development from the Perspective of the Innovation Value Chain”[Grant number.KJQN202000540].
文摘This study examines the effects of digital financial inclusion on non-farm employment of rural labor and the mediating mechanism of innovation and entrepreneurship activity using China Family Panel Studies(CFPS)and the provincial index of digital financial inclusion.Through the empirical test of the Probit model and mediation effect model,we found that:firstly,digital financial inclusion can promote non-farm employment of rural labor,with the level of digitalization having the most significant impact;secondly,by encouraging innovation and entrepreneurial activity,digital financial inclusion can promote non-farm employment of rural labor;thirdly,the driving effect of digital financial inclusion on non-farm employment of rural labor is more pronounced among the unmarried,eastern region,and male labor.Therefore,we should improve the construction of rural digital infrastructure and accelerate the development of inclusive rural finance to promote more diversified non-farm employment options for“disadvantaged groups”;encourage and support innovation at the government level,and create a favorable atmosphere for innovation and entrepreneurship.Simultaneously,farmers’digital literacy and financial knowledge should be improved so that more can adopt and take advantage of digital financial inclusion.
基金supported by grants from the National Natural Science Foundation of China(Grant No.82070206)Tianjin Key Medical Discipline(Specialty)Construction Project(Grant No.TJYXZDXK-053B).
文摘Diffuse large B-cell lymphoma(DLBCL)is the most common non-Hodgkin’s lymphoma(NHL)and has high heterogeneity.Approximately 30%–50%of patients develop relapsed/refractory(R/R)disease,which remains a major cause of mortality1-3.In recent years,a variety of novel therapies have emerged,including bispecific T-cell engagers(BiTEs),antibody–drug conjugates(ADCs),chimeric antigen receptor T cells(CAR-T),and selective BTK inhibitors,which have provided effective treatment strategies for patients with DLBCL1,4.Recently,the 58th Annual Meeting of the American Society of Clinical Oncology(ASCO)was held in Chicago,presenting cutting-edge studies in DLBCL.Here,we discuss a selection of interesting data on this topic.
基金financially supported by the National Key Research and Development Program of China(No.2022YFB3606502)the National Natural Science Foundation of China(Nos.52131304 and 62004101).
文摘Quasi-two-dimensional perovskite light-emitting diodes (quasi-2D PeLEDs) are emerging as high-potential candidates for new generation of wide-color gamut displays due to their simple, low-cost solution process, and high color purity. However, the luminescence performance of quasi-2D perovskite films is severely limited by dispersed phase distribution and excessive defect density, which are caused by excessive diffusion of nucleation sites during the perovskite growth stage. Here, the benzylphosphonic acid (BPA) molecule, owing to its strong P-O-Pb bond energy sites and strong electronegativity to PEA+, can aggregate lead-halide octahedron to grow high-dimensional phases, avoiding scattered low-dimensional phases (n = 1). The continuous gradient phase distribution will be beneficial to smooth carrier injection and effectively suppress the leakage current in PeLEDs. Meanwhile, the introduction of phosphonic acid groups will fill the vacancies of Pb ions and reduce non-radiative recombination. As a result, the maximum external quantum efficiency (EQE) of PeLEDs can be increased from 8% to 20.6% with a 514 nm light emission and a 21 nm full-width half maximum, and the device lifetime (T 50) is nearly 6-fold of the pristine sample. In addition, this strategy is also suitable for other wavelength. For example, in blue light, performance improvement is also realized that the maximum EQE of 8% and the luminance increased from 1045 to 5264 cd/m2. These results provide a feasible strategy to regulate the phase distribution and passivate the defects of quasi-2D perovskites.
文摘Purpose Lymphoma has become a major threat to human health.Fortunately,the diagnosis and treatment of lymphoma have developed rapidly,and research progress has emerged in an endless stream,with new drugs emerging one after another.These results are constantly rewriting guidelines changing clinical practice,need to be popularized and applied more widely.Methods This guideline has integrated consensuses reached by the Lymphoma Committee of China Anti-Cancer Association(CACA),based on China’s practice,tracking previous results of the most advanced clinical researches,absorbing the latest clinical evidence,and referring to domestic and international lymphoma guidelines.Results This holistic integrative guideline of lymphoma introduces the latest progress in the diagnosis and treatment of different subtypes of lymphoma,guide the clinical application of new drugs,standardized and precise management for lymphoma patients.Conclusions CACA guidelines for holistic integrative management of lymphoma(version 2022)enhance standardization and precision of the management for lymphoma patients in China.
基金support from the National Natural Science Foundation of China(51772197,51502184,51422206,51372159,51872191)1000 Youth Talents Plan,Key University Science Research Project of Jiangsu Province(17KJA430013)333 High-level Talents Cultivation Project of Jiangsu Province,Six Talents Peak Project of Jiangsu Province,and funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
文摘Due to its excellent electrical and optical features,silicon(Si)is highly attractive for photodetector applications.The design and fabrication of low-dimensional semiconductor/Si hybrid heterostructures provide a great platform for fabricating high-performance photodetectors,thereby overcoming the inherent limitations of Si.This review focuses on state-of-the-art Si heterostructure-based photodetectors.It starts with the introduction of three different device configurations,that is,photoconductors,photodiodes,and phototransistors.Their working mechanisms and relative pros and cons are introduced,and the figures of merit of photodetectors are summarized.Then,we discuss the device physics/design,photodetection performance,and optimization strategies for Si-based photodetectors.Finally,future challenges in the photodetector applications of Si-based hybrid heterostructures are discussed.
