Chiglitazar sodium is a new peroxisome proliferator-activated receptor(PPAR)pan-agonist with independent intellectual property rights in China.It can treat type 2 diabetes mellitus and regulate metabolism by modestly ...Chiglitazar sodium is a new peroxisome proliferator-activated receptor(PPAR)pan-agonist with independent intellectual property rights in China.It can treat type 2 diabetes mellitus and regulate metabolism by modestly activating PPARα,PPARγ,and PPARδto improve insulin sensitivity,regulate blood glucose,and promote fatty acid oxidation and utilization.Chiglitazar sodium has a significant insulin-sensitizing effect and is advantageous in reducing fasting and postprandial blood glucose levels,particularly at the 48 mg dose in patients with concomitant high triglycerides in terms of blood glucose and triglyceride level control.展开更多
目的:探究不同光固化模式和乙醇湿粘接对牙本质粘结强度及耐久性的影响,为临床应用提供理论指导。创新点:率先将乙醇湿粘接技术和不同光固化模式有机结合,成功筛选出了提高牙本质粘结性能的有效策略。方法:将Single Bond 2(SB)组、Gluma...目的:探究不同光固化模式和乙醇湿粘接对牙本质粘结强度及耐久性的影响,为临床应用提供理论指导。创新点:率先将乙醇湿粘接技术和不同光固化模式有机结合,成功筛选出了提高牙本质粘结性能的有效策略。方法:将Single Bond 2(SB)组、Gluma Comfort Bond(GB)组和N-Bond(NB)组分别分为6个亚组:高光照射模式、乙醇预处理+高光照射模式、软启动照射模式、乙醇预处理+软启动照射模式、标准照射模式和乙醇预处理+标准照射模式。按照分组粘结,水储24小时和6个月后,应用万能测试机分别检测微拉伸强度,体视显微镜观察微拉伸试件断裂类型和扫描电镜观察混合层形态。结论:乙醇湿粘接技术可以改善混合层质量,从而提高其粘结强度和改善粘结耐久性;软启动光照模式和标准光照模式可以形成更好的混合层质量,获得更高的牙本质粘结强度和更好的粘结耐久性。展开更多
文摘Chiglitazar sodium is a new peroxisome proliferator-activated receptor(PPAR)pan-agonist with independent intellectual property rights in China.It can treat type 2 diabetes mellitus and regulate metabolism by modestly activating PPARα,PPARγ,and PPARδto improve insulin sensitivity,regulate blood glucose,and promote fatty acid oxidation and utilization.Chiglitazar sodium has a significant insulin-sensitizing effect and is advantageous in reducing fasting and postprandial blood glucose levels,particularly at the 48 mg dose in patients with concomitant high triglycerides in terms of blood glucose and triglyceride level control.
基金Project supported by the Science and Technology Research Project of the Education Department of Jilin Province of China(No.(2015)527)
文摘目的:探究不同光固化模式和乙醇湿粘接对牙本质粘结强度及耐久性的影响,为临床应用提供理论指导。创新点:率先将乙醇湿粘接技术和不同光固化模式有机结合,成功筛选出了提高牙本质粘结性能的有效策略。方法:将Single Bond 2(SB)组、Gluma Comfort Bond(GB)组和N-Bond(NB)组分别分为6个亚组:高光照射模式、乙醇预处理+高光照射模式、软启动照射模式、乙醇预处理+软启动照射模式、标准照射模式和乙醇预处理+标准照射模式。按照分组粘结,水储24小时和6个月后,应用万能测试机分别检测微拉伸强度,体视显微镜观察微拉伸试件断裂类型和扫描电镜观察混合层形态。结论:乙醇湿粘接技术可以改善混合层质量,从而提高其粘结强度和改善粘结耐久性;软启动光照模式和标准光照模式可以形成更好的混合层质量,获得更高的牙本质粘结强度和更好的粘结耐久性。