Buyang Huanwu Decoction fraction extracted from Buyang Huanwu Decoction contains saponins of Astragalus, total paeony glycoside and safflower flavones. The aim of this study was to demonstrate the neuroprotective effe...Buyang Huanwu Decoction fraction extracted from Buyang Huanwu Decoction contains saponins of Astragalus, total paeony glycoside and safflower flavones. The aim of this study was to demonstrate the neuroprotective effect and mechanism of Buyang Huanwu Decoction fraction on ischemic injury both in vivo and in vitro. In vivo experiments showed that 50-200 mg/kg Buyang Huanwu Decoction fraction reduced infarct volume and pathological injury in ischemia/reperfusion rats, markedly inhibited expression of nuclear factor-κB and tumor necrosis factor-α and promoted nestin protein expression in brain tissue. Buyang Huanwu Decoction fraction (200 mg/kg) exhibited significant effects, which were similar to those of 100 mg/kg Ginkgo biloba extract. In vitro experimental results demonstrated that 10-100 mg/L Buyang Huanwu Decoction fraction significantly improved cell viability, decreased the release of lactate dehydrogenase and malondialdehyde levels, and inhibited the rate of apoptosis in HT22 cells following oxygen-glucose deprivation. Buyang Huanwu Decoction fraction (100 mg/L) exhibited significant effects, which were similar to those of 100 mg/L Ginkgo biloba extract. These findings suggest that Buyang Huanwu Decoction fraction may represent a novel, protective strategy against cerebral ischemia/reperfusion injury in rats and oxygen-glucose deprivation-induced damage in HT22 cells in vitro by attenuating the inflammatory response and cellular apoptosis.展开更多
We aim to understand the properties at the locations of supernova(SN) explosions in their host galaxies and compare with the global properties of these host galaxies. We use the integral field spectrograph(IFS) of Map...We aim to understand the properties at the locations of supernova(SN) explosions in their host galaxies and compare with the global properties of these host galaxies. We use the integral field spectrograph(IFS) of Mapping Nearby Galaxies at Apache Point Observatory(MaNGA) to generate 2 D maps of the parameter properties for 11 SN host galaxies. The sample galaxies are analyzed one by one in detail in terms of their properties of velocity field, star formation rate, oxygen abundance, stellar mass, etc.This sample of SN host galaxies has redshifts around z^0.03, which is higher than those of previous related works. The higher redshift distribution allows us to obtain the properties of more distant SN host galaxies. Metallicity(gas-phase oxygen abundance) estimated from integrated spectra can represent the local metallicity at SN explosion sites with small bias. All the host galaxies in our sample are metal-rich galaxies(12+log(O/H)> 8.5) except for NGC 6387, which means SNe may be more inclined to explode in metallicity-rich galaxies. There is a positive relation between global gas-phase oxygen abundance and the stellar mass of host galaxies. We also try to compare the differences of the host galaxies between SNe Ia and SNe II. In our sample, both SNe Ia and SNe II can explode in normal galaxies, but SNe II can also explode in an interacting or a merging system, in which star formation is occurring in the galaxy.展开更多
We select 947 star-forming galaxies from SDSS-DR7 with [O III]λ4363emission lines detected at a signal-to-noise ratio larger than 5σ. Their electron temperatures and direct oxygen abundances are then determined. We ...We select 947 star-forming galaxies from SDSS-DR7 with [O III]λ4363emission lines detected at a signal-to-noise ratio larger than 5σ. Their electron temperatures and direct oxygen abundances are then determined. We compare the results from different methods. t2, the electron temperature in the low ionization region, estimated from t3, that in the high ionization region, is compared using three analysis relations between t2- t3. These show obvious differences, which result in some different ionic oxygen abundances. The results of t3, t2, O++/H+and O+/H+derived by using methods from IRAF and literature are also compared. The ionic abundances O++/H+are higher than O+/H+for most cases. The different oxygen abundances derived from Teand the strong-line ratios show a clear discrepancy, which is more obvious following increasing stellar mass and strong-line ratio R23. The sample of galaxies from SDSS with detected [O III]λ4363 have lower metallicites and higher star formation rates, so they may not be typical representatives of the whole population of galaxies. Adopting data objects from Andrews & Martini, Liang et al. and Lee et al. data, we derive new relations of stellar mass and metallicity for star-forming galaxies in a much wider stellar mass range: from 106 M to 1011 M.展开更多
The Spitzer Extended Deep Survey(SEDS)as a deep and wide mid-infrared(MIR)survey project provides a sample of 500000+sources spreading 1.46 square degree and a depth of 26 AB mag(3σ).Combining with the previous avail...The Spitzer Extended Deep Survey(SEDS)as a deep and wide mid-infrared(MIR)survey project provides a sample of 500000+sources spreading 1.46 square degree and a depth of 26 AB mag(3σ).Combining with the previous available data,we build a PSF-matched multi-wavelength photometry catalog from u band to 8μm.We fit the SEDS galaxies spectral energy distributions by the local galaxy templates.The results show that the SEDS galaxy can be fitted well,indicating the high redshift galaxy(z~1)shares the same templates with the local galaxies.This study would facilitate the further study of the galaxy luminosity and high redshift mass function.展开更多
By using Data Analysis Pipeline(DAP)products of Mapping Nearby Galaxies at Apache Point Observatory(MaNGA),which are publicly available from the SDSS Data Release 15,we analyze the local properties at the SN explosion...By using Data Analysis Pipeline(DAP)products of Mapping Nearby Galaxies at Apache Point Observatory(MaNGA),which are publicly available from the SDSS Data Release 15,we analyze the local properties at the SN explosion sites and global properties of different types of SN host galaxies to explore the explosion environments of different types of SNe.In our sample,there are 67 SN host galaxies in the field of view of MaNGA,including 32 Type Ia,29 core collapse SNe(CCSNe),1 superluminous SN(SLSN),1 Type I and 4 unclassified type of SNe,with which we can apply the K-S test for analysis and derive statistically robust results.Due to the limited sample size,we could not remove the mass dependence in this work,which is likely the true driver of the trends for the properties presented in this work.The global star formation rate(SFR)and EW(H)for SN Ia hosts are slightly lower than those for CCSN hosts on average.SN Ia host galaxies are0.3 dex more massive than CCSN hosts,which implies that the number ratio of CCSNe to Type Ia SNe will decrease with increasing stellar mass of host galaxies.The stellar population age of SN Ia host galaxies is older than that of CCSN hosts on average.There is no significant difference between different types of SN hosts for some properties,including local SFR density(SFR),and local and global gas-phase oxygen abundance.For most galaxies in our sample,the global gas-phase oxygen abundance estimated from the integrated spectra of SN hosts can represent the local gas-phase oxygen abundance at the SN explosion sites with small bias.展开更多
How low surface brightness galaxies(LSBGs)form stars and assemble stellar mass is one of the most important questions related to understanding the LSBG population.We select a sample of 381 HI bright LSBGs with both fa...How low surface brightness galaxies(LSBGs)form stars and assemble stellar mass is one of the most important questions related to understanding the LSBG population.We select a sample of 381 HI bright LSBGs with both far ultraviolet(FUV)and near infrared(NIR)observations to investigate the star formation rate(SFR)and stellar mass scales,and the growth mode.We measure the FUV and NIR radii of our sample,which represent the star-forming and stellar mass distribution scales respectively.We also compare the FUV and H band radius-stellar mass relation with archival data,to identify the SFR and stellar mass structure difference between the LSBG population and other galaxies.Since galaxy HI mass has a tight correlation with the HI radius,we can also compare the HI and FUV radii to understand the distribution of HI gas and star formation activities.Our results show that most of the HI selected LSBGs have extended star formation structure.The stellar mass distribution of LSBGs may have a similar structure to disk galaxies at the same stellar mass bins,but the star-forming activity of LSBGs happens at a larger radius than the high surface density galaxies,which may help to identify the LSBG sample from the wide-field deep u band image survey.The HI is also distributed at larger radii,implying a steeper(or not)Kennicutt-Schmidt relation for LSBGs.展开更多
Minimally invasive surgeries,including laparoscopic,endoscopic,and robotic surgeries,have gained great popularity and have gradually replaced conventional open surgeries.Commonly,patients may have perioperative psycho...Minimally invasive surgeries,including laparoscopic,endoscopic,and robotic surgeries,have gained great popularity and have gradually replaced conventional open surgeries.Commonly,patients may have perioperative psychological issues such as anxiety,depression,sleep disturbance,and delirium.A comprehensive literature review was conducted to identify how these psychological issues occur in minimally invasive surgeries and how nurses can take better care of patients to alleviate these issues.Only papers focusing on psychological issues during the perioperative period were included in the re-view,and preexisting issues before the setting of surgical treatment plan were not discussed.Compared to conventional surgeries,the incidence of postoperative anxiety,preoperative depression,and sleep disturbance is lower in minimally invasive surgeries,the incidence of postoperative depression may be higher with limited evidence,and the incidence of preoperative anxiety and delirium is inconclusive.Systematic perioperative nursing programs not only alleviate psychological issues,but also reduce postsurgical complications and accelerate recovery.However,special nursing programs to handle delirium are lacking.展开更多
The 2019 novel coronavirus disease(COVID-19)has now swept through the continents and poses a global threat to public health.Several investigations have been conducted to identify whether COVID-19 can be transmitted th...The 2019 novel coronavirus disease(COVID-19)has now swept through the continents and poses a global threat to public health.Several investigations have been conducted to identify whether COVID-19 can be transmitted through the ocular route,and the conclusion is that it is a potential route but remains uncertain.Due to the faceto-face communication with patients,frequent exposure to tears and ocular discharge,and the unavoidable use of equipment which requires close proximity,ophthalmologists carry a high risk of contracting severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Based on 33 articles published by Chinese scholars,guidelines and clinical practice experience in domestic hospitals,we have summarized the Chinese experience through the lens of ophthalmology,hoping to make a contribution to protecting ophthalmologists and patients around the world.展开更多
Purpose:To assess the efficacy and safety of a novel ophthalmic viscosurgical device-free(OVD-free)method for posterior chamber phakic intraocular lens(PIOL)implantation in myopic eyes.Methods:In this retrospective co...Purpose:To assess the efficacy and safety of a novel ophthalmic viscosurgical device-free(OVD-free)method for posterior chamber phakic intraocular lens(PIOL)implantation in myopic eyes.Methods:In this retrospective cohort study,the medical records of myopic eyes that underwent PIOL(Implantable Collamer Lens,ICL)implantation for myopia correction at the Eye Hospital of Wenzhou Medical University between May 2015 and March 2017 were reviewed.A total of 49 eyes with complete data that met follow up requirements(2 h,1 day,1 week,3 months postoperatively)were recruited.Based on the surgical techniques used,the eyes were divided into the OVD-free method group and the standard method group.The clinical data,including intraocular pressure(IOP),corrected distance visual acuity(CDVA)and spherical equivalent(SE),at each follow-up were collected for comparison.Endothelial cell loss and complications were also investigated.Results:Twenty-one eyes received the standard method,and 28 eyes received the OVD-free method.A rise in IOP>22 mmHg at 2 h was noted in 14 eyes(66.7%)in the standard group and none(0%)in the OVD-free group(p<0.001).The rise in IOP from baseline was significantly higher at 2 h in the standard group(10.5±5.2 mmHg vs.2.2±3.3 mmHg,difference:8.3,95%CI 5.8 to 10.8;p<0.001).There was a significant difference in the time course of LogMAR CDVA changes between the two groups(p=0.047).The LogMAR CDVA was significantly better in the OVD-free method group compared to the standard group at 1 day(−0.076,95%CI−0.134 to−0.018;p=0.012),1 week(−0.071,95%CI−0.135 to−0.007;p=0.03),but not at 3 months(−0.046,95%CI−0.107 to 0.015;p=0.134).There was no significant difference in the time course of SE changes between the two groups(p=0.471;p=0.705).In the OVD-free group,mean endothelial cell loss was 4.6%at 3 months(2522±281 vs.2407±226 cells/mm^(2),difference:-115,95%CI−295 to 65;p=0.187).No complications were reported in both groups except for the early IOP elevation in the standard group during the observation period.Conclusions:The OVD-free method is safe and efficient for ICL implantation.It can be a safer method of ICL implantation compared to the standard method in that it completely eliminates ophthalmic viscoelastic devicesrelated complications without causing additional complications.展开更多
FTIR-ATR technology is used to study the efflorescence kinetic of Na_2SO_4 and mixed Na_2SO_4/CTAB aerosols.As the RH decreased linearly,the v_3-SO_4~2 band shifts from 1094 cm^1 to 1132 cm^1,suggesting the phase tran...FTIR-ATR technology is used to study the efflorescence kinetic of Na_2SO_4 and mixed Na_2SO_4/CTAB aerosols.As the RH decreased linearly,the v_3-SO_4~2 band shifts from 1094 cm^1 to 1132 cm^1,suggesting the phase transition of Na_2SO_4 from solution to crystal phase(Ⅲ).For pure Na_2SO_4 aerosols,the ERH is 75.1%RH,whereas the efflorescence point of mixed Na_2SO_4/CTAB aerosols(74.2%) is lower.By further analysis of IR differential spectra,the ratio of Na_2SO_4 crystals in mixed aerosols is only 62.7%and the heterogeneous nucleation rate of Na_2SO_4 in Na_2SO_4/CTAB mixed aerosols is lower than that in pure Na_2SO_4 aerosols.They showed that CTAB assembled into reversed micelle and part Na_2SO_4 droplets are in the core to form core-shell structure,and CTAB shell prevents core Na_2SO_4 solutions from crystallizing.However,the counter ion Br for CTAB reversed micelle can interact with Na^+ ions,which decreases the crystallization rate of free Na_2SO_4 droplets and ERH is delayed.展开更多
基金supported by a grant from the Major Programs of Anhui Science and Technology Special Funds,No.08010302099the Doctor Funds of Anhui Medical University,No.XJ200813
文摘Buyang Huanwu Decoction fraction extracted from Buyang Huanwu Decoction contains saponins of Astragalus, total paeony glycoside and safflower flavones. The aim of this study was to demonstrate the neuroprotective effect and mechanism of Buyang Huanwu Decoction fraction on ischemic injury both in vivo and in vitro. In vivo experiments showed that 50-200 mg/kg Buyang Huanwu Decoction fraction reduced infarct volume and pathological injury in ischemia/reperfusion rats, markedly inhibited expression of nuclear factor-κB and tumor necrosis factor-α and promoted nestin protein expression in brain tissue. Buyang Huanwu Decoction fraction (200 mg/kg) exhibited significant effects, which were similar to those of 100 mg/kg Ginkgo biloba extract. In vitro experimental results demonstrated that 10-100 mg/L Buyang Huanwu Decoction fraction significantly improved cell viability, decreased the release of lactate dehydrogenase and malondialdehyde levels, and inhibited the rate of apoptosis in HT22 cells following oxygen-glucose deprivation. Buyang Huanwu Decoction fraction (100 mg/L) exhibited significant effects, which were similar to those of 100 mg/L Ginkgo biloba extract. These findings suggest that Buyang Huanwu Decoction fraction may represent a novel, protective strategy against cerebral ischemia/reperfusion injury in rats and oxygen-glucose deprivation-induced damage in HT22 cells in vitro by attenuating the inflammatory response and cellular apoptosis.
基金supported by the National Natural Science Foundation of China (Grant Nos. 11733006, 11273026, 11233004 and U1631105)
文摘We aim to understand the properties at the locations of supernova(SN) explosions in their host galaxies and compare with the global properties of these host galaxies. We use the integral field spectrograph(IFS) of Mapping Nearby Galaxies at Apache Point Observatory(MaNGA) to generate 2 D maps of the parameter properties for 11 SN host galaxies. The sample galaxies are analyzed one by one in detail in terms of their properties of velocity field, star formation rate, oxygen abundance, stellar mass, etc.This sample of SN host galaxies has redshifts around z^0.03, which is higher than those of previous related works. The higher redshift distribution allows us to obtain the properties of more distant SN host galaxies. Metallicity(gas-phase oxygen abundance) estimated from integrated spectra can represent the local metallicity at SN explosion sites with small bias. All the host galaxies in our sample are metal-rich galaxies(12+log(O/H)> 8.5) except for NGC 6387, which means SNe may be more inclined to explode in metallicity-rich galaxies. There is a positive relation between global gas-phase oxygen abundance and the stellar mass of host galaxies. We also try to compare the differences of the host galaxies between SNe Ia and SNe II. In our sample, both SNe Ia and SNe II can explode in normal galaxies, but SNe II can also explode in an interacting or a merging system, in which star formation is occurring in the galaxy.
基金Supported by the National Natural Science Foundation of China
文摘We select 947 star-forming galaxies from SDSS-DR7 with [O III]λ4363emission lines detected at a signal-to-noise ratio larger than 5σ. Their electron temperatures and direct oxygen abundances are then determined. We compare the results from different methods. t2, the electron temperature in the low ionization region, estimated from t3, that in the high ionization region, is compared using three analysis relations between t2- t3. These show obvious differences, which result in some different ionic oxygen abundances. The results of t3, t2, O++/H+and O+/H+derived by using methods from IRAF and literature are also compared. The ionic abundances O++/H+are higher than O+/H+for most cases. The different oxygen abundances derived from Teand the strong-line ratios show a clear discrepancy, which is more obvious following increasing stellar mass and strong-line ratio R23. The sample of galaxies from SDSS with detected [O III]λ4363 have lower metallicites and higher star formation rates, so they may not be typical representatives of the whole population of galaxies. Adopting data objects from Andrews & Martini, Liang et al. and Lee et al. data, we derive new relations of stellar mass and metallicity for star-forming galaxies in a much wider stellar mass range: from 106 M to 1011 M.
基金supported by the National Key R&D Program of China(Grant No.2017YFA0402704)the National Natural Science Foundation of China(Grant Nos.11803044 and 11933003)+2 种基金the China Manned Space Project with No.CMSCSST-2021-A05sponsored(in part)by the Chinese Academy of Sciences(CAS)through a grant to the CAS South America Center for Astronomy(CASSACA)。
文摘The Spitzer Extended Deep Survey(SEDS)as a deep and wide mid-infrared(MIR)survey project provides a sample of 500000+sources spreading 1.46 square degree and a depth of 26 AB mag(3σ).Combining with the previous available data,we build a PSF-matched multi-wavelength photometry catalog from u band to 8μm.We fit the SEDS galaxies spectral energy distributions by the local galaxy templates.The results show that the SEDS galaxy can be fitted well,indicating the high redshift galaxy(z~1)shares the same templates with the local galaxies.This study would facilitate the further study of the galaxy luminosity and high redshift mass function.
基金the National Science Foundation of China(Grant No.11733006 to HW,11903046 to JG and U1631105 to WB)the Beijing Municipal Natural Science Foundation(No.1204038 to JG).
文摘By using Data Analysis Pipeline(DAP)products of Mapping Nearby Galaxies at Apache Point Observatory(MaNGA),which are publicly available from the SDSS Data Release 15,we analyze the local properties at the SN explosion sites and global properties of different types of SN host galaxies to explore the explosion environments of different types of SNe.In our sample,there are 67 SN host galaxies in the field of view of MaNGA,including 32 Type Ia,29 core collapse SNe(CCSNe),1 superluminous SN(SLSN),1 Type I and 4 unclassified type of SNe,with which we can apply the K-S test for analysis and derive statistically robust results.Due to the limited sample size,we could not remove the mass dependence in this work,which is likely the true driver of the trends for the properties presented in this work.The global star formation rate(SFR)and EW(H)for SN Ia hosts are slightly lower than those for CCSN hosts on average.SN Ia host galaxies are0.3 dex more massive than CCSN hosts,which implies that the number ratio of CCSNe to Type Ia SNe will decrease with increasing stellar mass of host galaxies.The stellar population age of SN Ia host galaxies is older than that of CCSN hosts on average.There is no significant difference between different types of SN hosts for some properties,including local SFR density(SFR),and local and global gas-phase oxygen abundance.For most galaxies in our sample,the global gas-phase oxygen abundance estimated from the integrated spectra of SN hosts can represent the local gas-phase oxygen abundance at the SN explosion sites with small bias.
基金supported by the National Key R&D Program of China(Grant 2017YFA0402704)by the National Natural Science Foundation of China(NSFC,Nos.11803044,11933003,11673028)+3 种基金sponsored(in part)by the Chinese Academy of Sciences(CAS),through a grant to the CAS South America Center for Astronomy(CASSACA)supported by the NSFC(Nos.U1931109 and 11733006)the Young Researcher Grant funded by National Astronomical Observatories,Chinese Academy of Sciences(CAS)the Youth Innovation Promotion Association,CAS。
文摘How low surface brightness galaxies(LSBGs)form stars and assemble stellar mass is one of the most important questions related to understanding the LSBG population.We select a sample of 381 HI bright LSBGs with both far ultraviolet(FUV)and near infrared(NIR)observations to investigate the star formation rate(SFR)and stellar mass scales,and the growth mode.We measure the FUV and NIR radii of our sample,which represent the star-forming and stellar mass distribution scales respectively.We also compare the FUV and H band radius-stellar mass relation with archival data,to identify the SFR and stellar mass structure difference between the LSBG population and other galaxies.Since galaxy HI mass has a tight correlation with the HI radius,we can also compare the HI and FUV radii to understand the distribution of HI gas and star formation activities.Our results show that most of the HI selected LSBGs have extended star formation structure.The stellar mass distribution of LSBGs may have a similar structure to disk galaxies at the same stellar mass bins,but the star-forming activity of LSBGs happens at a larger radius than the high surface density galaxies,which may help to identify the LSBG sample from the wide-field deep u band image survey.The HI is also distributed at larger radii,implying a steeper(or not)Kennicutt-Schmidt relation for LSBGs.
基金funded by the Medical Health Science and Technology Project of Hangzhou Municipal Health Commission to Kehua Yang(A20200709).
文摘Minimally invasive surgeries,including laparoscopic,endoscopic,and robotic surgeries,have gained great popularity and have gradually replaced conventional open surgeries.Commonly,patients may have perioperative psychological issues such as anxiety,depression,sleep disturbance,and delirium.A comprehensive literature review was conducted to identify how these psychological issues occur in minimally invasive surgeries and how nurses can take better care of patients to alleviate these issues.Only papers focusing on psychological issues during the perioperative period were included in the re-view,and preexisting issues before the setting of surgical treatment plan were not discussed.Compared to conventional surgeries,the incidence of postoperative anxiety,preoperative depression,and sleep disturbance is lower in minimally invasive surgeries,the incidence of postoperative depression may be higher with limited evidence,and the incidence of preoperative anxiety and delirium is inconclusive.Systematic perioperative nursing programs not only alleviate psychological issues,but also reduce postsurgical complications and accelerate recovery.However,special nursing programs to handle delirium are lacking.
基金Supported by the Natural and Science Foundation of China(Grant No.81570869)Wenzhou Key Team of Scientific and Technological Innovation(Grant No.C20170002).
文摘The 2019 novel coronavirus disease(COVID-19)has now swept through the continents and poses a global threat to public health.Several investigations have been conducted to identify whether COVID-19 can be transmitted through the ocular route,and the conclusion is that it is a potential route but remains uncertain.Due to the faceto-face communication with patients,frequent exposure to tears and ocular discharge,and the unavoidable use of equipment which requires close proximity,ophthalmologists carry a high risk of contracting severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Based on 33 articles published by Chinese scholars,guidelines and clinical practice experience in domestic hospitals,we have summarized the Chinese experience through the lens of ophthalmology,hoping to make a contribution to protecting ophthalmologists and patients around the world.
基金This study is supported by the National Natural Science Foundation of China(grant numbers 81570869)Zhejiang Provincial Natural Science Foundation of China(grant numbers Y2110784)+4 种基金Zhejiang Provincial Foundation of China for Distinguished Young Talents in Medicine and Health(grant numbers 2010QNA018)Wenzhou Key Team of Scientific and Technological Innovation(grant number C20170002)Foundation of Wenzhou City Science&Technology Bureau(grant numbers Y20140705)Engineering Development Project of Ophthalmology and Optometry(grant number GCKF201601)The funding organizations have no role in the design or conduct of this study.
文摘Purpose:To assess the efficacy and safety of a novel ophthalmic viscosurgical device-free(OVD-free)method for posterior chamber phakic intraocular lens(PIOL)implantation in myopic eyes.Methods:In this retrospective cohort study,the medical records of myopic eyes that underwent PIOL(Implantable Collamer Lens,ICL)implantation for myopia correction at the Eye Hospital of Wenzhou Medical University between May 2015 and March 2017 were reviewed.A total of 49 eyes with complete data that met follow up requirements(2 h,1 day,1 week,3 months postoperatively)were recruited.Based on the surgical techniques used,the eyes were divided into the OVD-free method group and the standard method group.The clinical data,including intraocular pressure(IOP),corrected distance visual acuity(CDVA)and spherical equivalent(SE),at each follow-up were collected for comparison.Endothelial cell loss and complications were also investigated.Results:Twenty-one eyes received the standard method,and 28 eyes received the OVD-free method.A rise in IOP>22 mmHg at 2 h was noted in 14 eyes(66.7%)in the standard group and none(0%)in the OVD-free group(p<0.001).The rise in IOP from baseline was significantly higher at 2 h in the standard group(10.5±5.2 mmHg vs.2.2±3.3 mmHg,difference:8.3,95%CI 5.8 to 10.8;p<0.001).There was a significant difference in the time course of LogMAR CDVA changes between the two groups(p=0.047).The LogMAR CDVA was significantly better in the OVD-free method group compared to the standard group at 1 day(−0.076,95%CI−0.134 to−0.018;p=0.012),1 week(−0.071,95%CI−0.135 to−0.007;p=0.03),but not at 3 months(−0.046,95%CI−0.107 to 0.015;p=0.134).There was no significant difference in the time course of SE changes between the two groups(p=0.471;p=0.705).In the OVD-free group,mean endothelial cell loss was 4.6%at 3 months(2522±281 vs.2407±226 cells/mm^(2),difference:-115,95%CI−295 to 65;p=0.187).No complications were reported in both groups except for the early IOP elevation in the standard group during the observation period.Conclusions:The OVD-free method is safe and efficient for ICL implantation.It can be a safer method of ICL implantation compared to the standard method in that it completely eliminates ophthalmic viscoelastic devicesrelated complications without causing additional complications.
基金financially supported by the National Natural Science Foundation of China (Nos. 21373026, 21473009.)
文摘FTIR-ATR technology is used to study the efflorescence kinetic of Na_2SO_4 and mixed Na_2SO_4/CTAB aerosols.As the RH decreased linearly,the v_3-SO_4~2 band shifts from 1094 cm^1 to 1132 cm^1,suggesting the phase transition of Na_2SO_4 from solution to crystal phase(Ⅲ).For pure Na_2SO_4 aerosols,the ERH is 75.1%RH,whereas the efflorescence point of mixed Na_2SO_4/CTAB aerosols(74.2%) is lower.By further analysis of IR differential spectra,the ratio of Na_2SO_4 crystals in mixed aerosols is only 62.7%and the heterogeneous nucleation rate of Na_2SO_4 in Na_2SO_4/CTAB mixed aerosols is lower than that in pure Na_2SO_4 aerosols.They showed that CTAB assembled into reversed micelle and part Na_2SO_4 droplets are in the core to form core-shell structure,and CTAB shell prevents core Na_2SO_4 solutions from crystallizing.However,the counter ion Br for CTAB reversed micelle can interact with Na^+ ions,which decreases the crystallization rate of free Na_2SO_4 droplets and ERH is delayed.
