Nail involvement is common in psoriasis and is considered a risk factor for and a predictor of the development of psoriatic arthritis.The treatment of nail psoriasis is challenging because of the unique anatomical str...Nail involvement is common in psoriasis and is considered a risk factor for and a predictor of the development of psoriatic arthritis.The treatment of nail psoriasis is challenging because of the unique anatomical structure of nails and the absence of standardized treatment protocols.Herein,we provide an up-to-date overview of the treatment options for nail psoriasis,including topical drugs and penetration enhancement strategies,traditional and novel oral drugs,and biologic agents.In addition,we highlight the available individualized management strategies in special patient populations such as pediatric patients,geriatric patients,women of childbearing age,and patients with concomitant onychomycosis or psoriatic arthritis.展开更多
基金This study was supported by CAMS Innovation Fund forMedical Sciences(No.CIFMS-2017-12M-1-017)the National Natural Science Foundation of China(Nos.81872545 and 81703152).
文摘Nail involvement is common in psoriasis and is considered a risk factor for and a predictor of the development of psoriatic arthritis.The treatment of nail psoriasis is challenging because of the unique anatomical structure of nails and the absence of standardized treatment protocols.Herein,we provide an up-to-date overview of the treatment options for nail psoriasis,including topical drugs and penetration enhancement strategies,traditional and novel oral drugs,and biologic agents.In addition,we highlight the available individualized management strategies in special patient populations such as pediatric patients,geriatric patients,women of childbearing age,and patients with concomitant onychomycosis or psoriatic arthritis.
