BACKGROUND Morgagni hernias are rare anomalies that are easily misdiagnosed or missed.AIM To summarize the ultrasound(US)imaging characteristics of Morgagni hernias through a comparison of imaging and surgical results...BACKGROUND Morgagni hernias are rare anomalies that are easily misdiagnosed or missed.AIM To summarize the ultrasound(US)imaging characteristics of Morgagni hernias through a comparison of imaging and surgical results.METHODS The records of children with Morgagni hernias who were hospitalized at two hospitals between January 2013 and November 2023 were retrospectively re-viewed in terms of clinical findings,US features,and operative details.RESULTS Between 2013 and 2023,we observed nine(five male and four female)children with Morgagni hernias.Upper abdominal scanning revealed a widening of the prehepatic space,with an abnormal channel extending from the xiphoid process to the right or left side of the thoracic cavity.The channel had intestinal duct and intestinal gas echoes.Hernia contents were found in the transverse colon(n=6),the colon and small intestine(n=2),and the colon and stomach(n=1).Among the patients,seven had a right-sided lesion,two had a left-sided lesion,and all of them had hernial sacs.CONCLUSION US imaging can accurately determine the location,extent,and content of Morgagni hernias.For suspected Mor-gagni hernias,we recommend performing sonographic screening first.展开更多
AIM: To evaluate the efficacy and tolerability of low-dose standard or pegylated interferon (PEG-IFN) in hepatitis C virus (HCV)-positive hemodialysis patients.
The isothermal compression dynamics of ternary Ti-6 Al-4 V alloy with initial martensitic structures were investigated in the high temperature range 1083-1173 K and moderate strain rate regime 0.01-10 s-1.Shear bandin...The isothermal compression dynamics of ternary Ti-6 Al-4 V alloy with initial martensitic structures were investigated in the high temperature range 1083-1173 K and moderate strain rate regime 0.01-10 s-1.Shear banding was found to still dominate the deformation mechanism of this process,despite its nonadiabatic feature.The constitutive equation was derived with the aid of Zener-Hollomon parameter,which predicted the apparent activation energy as 534.39 kJ/mol.A combination of higher deformation temperature and lower strain rate suppressed the peak flow stress and promoted the evolution of shear bands.Both experiments and calculations demonstrated that a conspicuous temperature rise up to 83 K could be induced by severe plastic deformation.This facilitated the dynamic recrystallization of deformed martensites,as evidenced by the measured microhardness profiles across shear bands.展开更多
Background：Compared with full-term infants, very preterm infants are more vulnerable to injury and long-term disability and are at high risk of death. The predictive value of ultrasound and imaging on the neurodevelo...Background：Compared with full-term infants, very preterm infants are more vulnerable to injury and long-term disability and are at high risk of death. The predictive value of ultrasound and imaging on the neurodevelopment is one of the hot topics. This study aimed to investigate the relationship between cranial ultrasound （cUS） variables and neurodevelopmental outcomes of very preterm infants.Methods：Totally 129 very preterm infants （gestational age ≤28 weeks） in neonatal intensive care unit of Hunan Children’s Hospital between January 2012 and November 2014 were included in this retrospective study. Serial cUS （weekly before discharge and monthly after discharge） was performed on the infants until 6 months or older. Magnetic resonance imaging （MRI） was performed on the infants at approximately the term-equivalent age. The mental developmental index （MDI） and psychomotor developmental index （PDI） were followed up until the infants were 24 months or older. The relationship between brain injury and MDI/PDI scores was analyzed.Results：The consistency rate between cUS and MRI was 88%. At the first cUS, germinal matrix hemorrhage （GMH） Grades 3 and 4, hospitalization duration, and weight are significantly correlated with MDI/PDI and prognosis （MDI： odds ratio [OR] = 8.415, 0.982, and 0.042, P = 0.016, 0.000, and 0.004; PDI： OR = 7.149, 0.978, and 0.012, P = 0.025, 0.000, and 0.000, respectively）. At the last cUS, gestational age, extensive cystic periventricular leukomalacia （c-PVL）, and moderate and severe hydrocephaly are significantly correlated with MDI （OR = 0.292, 60.220, and 170.375, P = 0.004, 0.003, and 0.000, respectively）. Extensive c-PVL and moderate and severe hydrocephaly are significantly correlated with PDI （OR = 76.861 and 116.746, P = 0.003 and 0.000, respectively）.Conclusions：Very premature infants with GMH Grades 3 and 4, short hospitalization duration, and low weight have low survival rates and poorly developed brain nerves. Cerebral palsy can result from severe cerebral hemorrhage, moderate and severe hydrocephaly, and extensive c-PVL. The sustained, inhomogeneous echogenicity of white matter may suggest subtle brain injury.展开更多
Objective： Studies have demonstrated that Tai Chi exercise improves blood lipid level with inconsistent results. A meta-analysis was conducted to quantify the effects of Tai Chi on blood lipid profiles in humans. Met...Objective： Studies have demonstrated that Tai Chi exercise improves blood lipid level with inconsistent results. A meta-analysis was conducted to quantify the effects of Tai Chi on blood lipid profiles in humans. Methods： We screened the databases of PubMed, EMBASE, Cochrane Library （Central）, Web of Science, China National Knowledge Infrastructure （CNKI）, Wanfang data, and Clinicaltrials.gov for randomized controlled trials with Physio- therapy Evidence Database （PEDro） score more than 3 points up to June 2015. Six studies involving 445 subjects were included. Most trials applied 12-week Tai Chi intervention courses. Results： In comparison with the control group, blood triglyceride （TG） level difference between follow-up and baseline was statistically significantly lower in the Tai Chi practicing group （weighted mean difference （WMD） -16.81 mg/dl; 95% confidence intervals （CI） -31.27 to -2.35 mg/dl; P=-0.02）. A trend to improving total cholesterol （TC） reduction was found with Tai Chi （WMD -7.96 mg/dl; 95% CI -17.30 to 1.39 mg/dl; P=-0.10）. However, no difference was found in blood low-density lipoprotein cholesterol （LDL-C） or high-density lipoprotein cholesterol （HDL-C）. Conclusions： Tai Chi exercise lowered blood TG level with a trend to decrease blood TC level. Our data suggest that Tai Chi has the potential to implement meaningful blood lipid modification and serve as an adjunctive exercise modality. The relationship between Tai Chi exercise regimen and lipid profile change might have a scientific priority for future investigation.展开更多
To the Editor:Survival rates for very pre-term infants have risen drastically in recent years owing to successful assistedventilation techniques;the latest prenatal and postnatal treatments;and modern,well-equipped,an...To the Editor:Survival rates for very pre-term infants have risen drastically in recent years owing to successful assistedventilation techniques;the latest prenatal and postnatal treatments;and modern,well-equipped,and well-staffed neonatal intensive care units?1Cranial ultrasound(cUS)is the primary imaging technique for evaluating brain injury in very pre-term infants.Very pre-term infants have several unique features related to their ongoing maturation,and associated findings on cUS should be considered for accurate and early diagnosis.13,41 The purpose of this study was to summarize the cUS characteristics of the brains of very premature infants of different gestational ages(GAs)<29 weeks to provide an understanding of the diagnosis of abnormal brain conditions.展开更多
基金Supported by Startup Fund for Scientific Research,Fujian Province Science and Technology Innovation Joint Fund Project,No.2021Y9188.
文摘BACKGROUND Morgagni hernias are rare anomalies that are easily misdiagnosed or missed.AIM To summarize the ultrasound(US)imaging characteristics of Morgagni hernias through a comparison of imaging and surgical results.METHODS The records of children with Morgagni hernias who were hospitalized at two hospitals between January 2013 and November 2023 were retrospectively re-viewed in terms of clinical findings,US features,and operative details.RESULTS Between 2013 and 2023,we observed nine(five male and four female)children with Morgagni hernias.Upper abdominal scanning revealed a widening of the prehepatic space,with an abnormal channel extending from the xiphoid process to the right or left side of the thoracic cavity.The channel had intestinal duct and intestinal gas echoes.Hernia contents were found in the transverse colon(n=6),the colon and small intestine(n=2),and the colon and stomach(n=1).Among the patients,seven had a right-sided lesion,two had a left-sided lesion,and all of them had hernial sacs.CONCLUSION US imaging can accurately determine the location,extent,and content of Morgagni hernias.For suspected Mor-gagni hernias,we recommend performing sonographic screening first.
文摘AIM: To evaluate the efficacy and tolerability of low-dose standard or pegylated interferon (PEG-IFN) in hepatitis C virus (HCV)-positive hemodialysis patients.
基金Supported by the National Natural Science Foundation of China(Grant No.51471136)the Fundamental Research Funds for Central Universities。
文摘The isothermal compression dynamics of ternary Ti-6 Al-4 V alloy with initial martensitic structures were investigated in the high temperature range 1083-1173 K and moderate strain rate regime 0.01-10 s-1.Shear banding was found to still dominate the deformation mechanism of this process,despite its nonadiabatic feature.The constitutive equation was derived with the aid of Zener-Hollomon parameter,which predicted the apparent activation energy as 534.39 kJ/mol.A combination of higher deformation temperature and lower strain rate suppressed the peak flow stress and promoted the evolution of shear bands.Both experiments and calculations demonstrated that a conspicuous temperature rise up to 83 K could be induced by severe plastic deformation.This facilitated the dynamic recrystallization of deformed martensites,as evidenced by the measured microhardness profiles across shear bands.
文摘Background：Compared with full-term infants, very preterm infants are more vulnerable to injury and long-term disability and are at high risk of death. The predictive value of ultrasound and imaging on the neurodevelopment is one of the hot topics. This study aimed to investigate the relationship between cranial ultrasound （cUS） variables and neurodevelopmental outcomes of very preterm infants.Methods：Totally 129 very preterm infants （gestational age ≤28 weeks） in neonatal intensive care unit of Hunan Children’s Hospital between January 2012 and November 2014 were included in this retrospective study. Serial cUS （weekly before discharge and monthly after discharge） was performed on the infants until 6 months or older. Magnetic resonance imaging （MRI） was performed on the infants at approximately the term-equivalent age. The mental developmental index （MDI） and psychomotor developmental index （PDI） were followed up until the infants were 24 months or older. The relationship between brain injury and MDI/PDI scores was analyzed.Results：The consistency rate between cUS and MRI was 88%. At the first cUS, germinal matrix hemorrhage （GMH） Grades 3 and 4, hospitalization duration, and weight are significantly correlated with MDI/PDI and prognosis （MDI： odds ratio [OR] = 8.415, 0.982, and 0.042, P = 0.016, 0.000, and 0.004; PDI： OR = 7.149, 0.978, and 0.012, P = 0.025, 0.000, and 0.000, respectively）. At the last cUS, gestational age, extensive cystic periventricular leukomalacia （c-PVL）, and moderate and severe hydrocephaly are significantly correlated with MDI （OR = 0.292, 60.220, and 170.375, P = 0.004, 0.003, and 0.000, respectively）. Extensive c-PVL and moderate and severe hydrocephaly are significantly correlated with PDI （OR = 76.861 and 116.746, P = 0.003 and 0.000, respectively）.Conclusions：Very premature infants with GMH Grades 3 and 4, short hospitalization duration, and low weight have low survival rates and poorly developed brain nerves. Cerebral palsy can result from severe cerebral hemorrhage, moderate and severe hydrocephaly, and extensive c-PVL. The sustained, inhomogeneous echogenicity of white matter may suggest subtle brain injury.
文摘Objective： Studies have demonstrated that Tai Chi exercise improves blood lipid level with inconsistent results. A meta-analysis was conducted to quantify the effects of Tai Chi on blood lipid profiles in humans. Methods： We screened the databases of PubMed, EMBASE, Cochrane Library （Central）, Web of Science, China National Knowledge Infrastructure （CNKI）, Wanfang data, and Clinicaltrials.gov for randomized controlled trials with Physio- therapy Evidence Database （PEDro） score more than 3 points up to June 2015. Six studies involving 445 subjects were included. Most trials applied 12-week Tai Chi intervention courses. Results： In comparison with the control group, blood triglyceride （TG） level difference between follow-up and baseline was statistically significantly lower in the Tai Chi practicing group （weighted mean difference （WMD） -16.81 mg/dl; 95% confidence intervals （CI） -31.27 to -2.35 mg/dl; P=-0.02）. A trend to improving total cholesterol （TC） reduction was found with Tai Chi （WMD -7.96 mg/dl; 95% CI -17.30 to 1.39 mg/dl; P=-0.10）. However, no difference was found in blood low-density lipoprotein cholesterol （LDL-C） or high-density lipoprotein cholesterol （HDL-C）. Conclusions： Tai Chi exercise lowered blood TG level with a trend to decrease blood TC level. Our data suggest that Tai Chi has the potential to implement meaningful blood lipid modification and serve as an adjunctive exercise modality. The relationship between Tai Chi exercise regimen and lipid profile change might have a scientific priority for future investigation.
基金The study was supported by a grant from the Hunan Provincial Science and Technology Department(No.2017SK50701).
文摘To the Editor:Survival rates for very pre-term infants have risen drastically in recent years owing to successful assistedventilation techniques;the latest prenatal and postnatal treatments;and modern,well-equipped,and well-staffed neonatal intensive care units?1Cranial ultrasound(cUS)is the primary imaging technique for evaluating brain injury in very pre-term infants.Very pre-term infants have several unique features related to their ongoing maturation,and associated findings on cUS should be considered for accurate and early diagnosis.13,41 The purpose of this study was to summarize the cUS characteristics of the brains of very premature infants of different gestational ages(GAs)<29 weeks to provide an understanding of the diagnosis of abnormal brain conditions.
