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Application Effect of Blended Education Strategy Based on the Learning Pass Platform in Phase III Cardiac Rehabilitation of Patients with Coronary Artery Disease
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作者 Shanshan Cui Guihua Xue +4 位作者 Xuelan Yan Hua Zhang Fang Wang Yan Xu xuefei li 《Journal of Contemporary Educational Research》 2024年第2期91-97,共7页
Objective:To explore the application effect of the blended education strategy based on the Learning Pass platform in the phase III cardiac rehabilitation of patients with coronary artery disease.Methods:90 patients di... Objective:To explore the application effect of the blended education strategy based on the Learning Pass platform in the phase III cardiac rehabilitation of patients with coronary artery disease.Methods:90 patients diagnosed with coronary artery disease in the Department of Cardiology of our hospital from January 2019 to January 2021 were selected and divided into the control group and the experimental group according to the method of randomized numerical table,with 45 cases in each group.Both the experimental group and the control group received pre-discharge cardiac rehabilitation education by conventional means.The control group received education and supervision information via WeChat after discharge,while the experimental group joined the Learning Pass platform to receive online and offline hybrid education and supervision,with online as the mainstay and offline as a supplement.The disease cognitive level,self-management skills,quality of life,medication adherence,and emotional status of the two groups were compared.Results:The disease cognitive levels in the experimental group were significantly higher than those of the control group(P<0.05);the scores of the experimental group in terms of quality of life,self-management skills,and medication adherence were significantly higher than those of the control group(P<0.05);and the scores of anxiety and depression in the experimental group were significantly lower than those of the control group(P<0.05).Conclusion:The blended education strategy based on the Learning Pass platform has a significant application effect in phase III cardiac rehabilitation of patients with coronary artery disease.It can improve patients’disease cognitive level,self-management skills,and quality of life,and provide a basis for improving patients’prognosis. 展开更多
关键词 Learning Pass platform Blended education Coronary artery disease Cardiac rehabilitation
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Application of Specialized Group Management in the Quality Control of Perioperative Nursing
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作者 Cong Fu xuefei li +4 位作者 li Wang Yuanyuan Jiang Xinrong Qi Chen Ding Shanshan Tang 《Journal of Clinical and Nursing Research》 2024年第2期70-75,共6页
Objective:To explore the role of specialized group management in the quality control of perioperative nursing.Methods:45 surgical nurses from our hospital were selected as the research subjects.Traditional operating r... Objective:To explore the role of specialized group management in the quality control of perioperative nursing.Methods:45 surgical nurses from our hospital were selected as the research subjects.Traditional operating room management was adopted from July 2019 to June 2020,and specialized group management was adopted from July 2020 to June 2021.The surgeon’s satisfaction,surgical nurses’core professional competence,and surgical patients’satisfaction were obtained through surveys and the results were analyzed.Results:Surgeon satisfaction before the implementation of specialized group management was significantly lower than after its implementation(P<0.05).Besides,surgical nurses’core professional competency scores before the implementation of specialized group management were significantly lower than after its implementation(P<0.05).Lastly,surgical patients’satisfaction before the implementation of specialized group management was significantly lower than after its implementation(P<0.05).Conclusion:Specialized group management helps to improve the quality of perioperative care and should be applied in clinical practice. 展开更多
关键词 Specialized group management Operating room Quality of care CONTROL
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Application Effect of Blended Education Strategy Based on the Learning Pass Platform in Phase III Cardiac Rehabilitation of Patients with Coronary Artery Disease
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作者 Shanshan Cui Guihua Xue +4 位作者 Xuelan Yan Hua Zhang Fang Wang Yan Xu xuefei li 《Journal of Contemporary Educational Research》 2023年第12期294-300,共7页
Objective:To explore the application effect of the blended education strategy based on the Learning Pass platform in the phase III cardiac rehabilitation of patients with coronary artery disease.Methods:90 patients di... Objective:To explore the application effect of the blended education strategy based on the Learning Pass platform in the phase III cardiac rehabilitation of patients with coronary artery disease.Methods:90 patients diagnosed with coronary artery disease in the Department of Cardiology of our hospital from January 2019 to January 2021 were selected and divided into the control group and the experimental group according to the method of randomized numerical table,with 45 cases in each group.Both the experimental group and the control group received pre-discharge cardiac rehabilitation education by conventional means.The control group received education and supervision information via WeChat after discharge,while the experimental group joined the Learning Pass platform to receive online and offline hybrid education and supervision,with online as the mainstay and offline as a supplement.The disease cognitive level,self-management skills,quality of life,medication adherence,and emotional status of the two groups were compared.Results:The disease cognitive levels in the experimental group were significantly higher than those of the control group(P<0.05);the scores of the experimental group in terms of quality of life,self-management skills,and medication adherence were significantly higher than those of the control group(P<0.05);and the scores of anxiety and depression in the experimental group were significantly lower than those of the control group(P<0.05).Conclusion:The blended education strategy based on the Learning Pass platform has a significant application effect in phase III cardiac rehabilitation of patients with coronary artery disease.It can improve patients’disease cognitive level,self-management skills,and quality of life,and provide a basis for improving patients’prognosis. 展开更多
关键词 Learning Pass platform Blended education Coronary artery disease Cardiac rehabilitation
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Progress in Investigating the Current Mental Health Status Among Caregivers for Surgical Oncology Patients
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作者 xuefei li li Wang +4 位作者 lian Xue Jian Yang Shanshan Cui Shanshan Tang Cong Fu 《Proceedings of Anticancer Research》 2024年第1期10-16,共7页
This article aims to discuss the current state and research progress concerning the mental health of caregivers for surgical oncology patients.The goal is to offer insights that can serve as a reference for further en... This article aims to discuss the current state and research progress concerning the mental health of caregivers for surgical oncology patients.The goal is to offer insights that can serve as a reference for further enhancements in caregivers’mental well-being.This article conducts a comprehensive review and analysis of recent studies on the mental health of caregivers for patients undergoing oncologic surgery.These studies reveal that caregivers commonly grapple with mental health issues,including anxiety,depression,and stress.These problems are closely linked to the stress of the patient’s condition and treatment,the caregiver’s own mental strain,and a lack of social support.In addition,the mental health status of caregivers significantly influences the patient’s treatment and recovery process.Implementing various interventions,such as mental health education,services,the establishment of mental health support teams,and engagement in mental health promotion activities,can contribute to the improvement of caregivers’mental well-being.This,in turn,has the potential to enhance treatment outcomes and the overall quality of life for patients. 展开更多
关键词 Tumor patients CAREGIVERS Mental health
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Uncommon EGFR mutations in a cohort of Chinese NSCLC patients and outcomes of first-line EGFR-TKIs and platinum-based chemotherapy 被引量:7
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作者 Jinpeng Shi Hui Yang +12 位作者 Tao Jiang xuefei li Chao Zhao limin Zhang Sha Zhao Xiaozhen liu Yijun Jia Yan Wang Lei Xi Shijia Zhang Chunxia Su Shengxiang Ren Caicun Zhou 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2017年第6期543-552,共10页
Objective: Data on the clinical activity of epidermal growth factor receptor(EGFR) tyrosine kinase inhibitors(TKIs) in patients with non-small-cell lung cancer(NSCLC) and uncommon EGFR mutations remain insufficient.Th... Objective: Data on the clinical activity of epidermal growth factor receptor(EGFR) tyrosine kinase inhibitors(TKIs) in patients with non-small-cell lung cancer(NSCLC) and uncommon EGFR mutations remain insufficient.This study aimed to investigate the effect of first-line EGFR-TKIs or platinum-based chemotherapy in NSCLC patients with uncommon EGFR mutations.Methods: We retrospectively enrolled 504 patients with EGFR-mutant NSCLC.The clinical characteristics and treatment outcomes were collected and compared between patients with common and uncommon EGFR-mutant NSCLC.Results: Seventy patients(13.9%) harboring uncommon EGFR mutations were included.Thirty of these patients received EGFR-TKIs and 40 received platinum-based chemotherapy as first-line therapy.The objective response rate(ORR) and median progression-free survival(m PFS) of patients treated with TKIs in the uncommon mutation group was significantly inferior to that in the common mutation group(ORR: 23.3% vs.51.8%,P=0.003; m PFS:7.1 vs.10.9 months,P<0.001).In the uncommon group,m PFS was similar between first-line EGFR-TKIs treatment and platinum-based chemotherapy(7.1 vs.6.1 months,P=0.893).In patients with EGFR G719 X or L861 Q mutations,the m PFS was longer in the first-line EGFR-TKIs treatment group than in the chemotherapy group,but the difference was not statistically significant(G719 X: 8.2 vs.5.8 months,P=0.061; L861 Q: 7.6 vs.4.1 months,P=0.872).Multivariate analyses identified adenocarcinoma(P=0.003) as the independent predictive factor for PFS in patients with uncommon EGFR mutations who were treated with first-line EGFR-TKIs.Conclusions: The current study demonstrated that the effect of first-line EGFR-TKIs was similar to that of platinum-based chemotherapy in patients with uncommon EGFR-mutant NSCLC.Adenocarcinoma was the independent predictive factor for PFS in uncommon EGFR-mutant NSCLC patients treated with first-line EGFRTKIs. 展开更多
关键词 EGFR 化疗 中国 人的因素 PFS 变异 治疗
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基于计算控制通信融合的车联网资源协同优化技术研究 被引量:1
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作者 张志龙 张天琦 +1 位作者 李雪菲 刘丹谱 《电信科学》 2023年第4期17-30,共14页
车联网高度动态且业务种类多样,安全业务和非安全业务并存。如何同时满足差异化的业务需求,是车联网面临的重大挑战。分析了计算、控制与通信等要素在车联网中的融合方式,并指出以协同管理多维资源提升驾驶安全性和业务体验质量的必要... 车联网高度动态且业务种类多样,安全业务和非安全业务并存。如何同时满足差异化的业务需求,是车联网面临的重大挑战。分析了计算、控制与通信等要素在车联网中的融合方式,并指出以协同管理多维资源提升驾驶安全性和业务体验质量的必要性。针对业务特点分别介绍了面向自动驾驶的控制与通信融合机制、面向信息娱乐业务的计算与通信资源协同管理机制以及面向差异化业务并发的多维资源协同管理机制,最后基于相关挑战展望了该领域未来的技术发展趋势。 展开更多
关键词 车联网 控制与通信融合 多维资源管理 自动驾驶 高动态
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The Study on the Framework and Implementation Scheme of the Railway Intelligent Cold Chain Logistics System
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作者 Wei Xu Gang li xuefei li 《Advances in Internet of Things》 2022年第3期110-123,共14页
With the development of intelligent and communication technology, traditional logistics has gradually transformed into intelligent logistics. The construction of the railway intelligent cold chain logistics system is ... With the development of intelligent and communication technology, traditional logistics has gradually transformed into intelligent logistics. The construction of the railway intelligent cold chain logistics system is an effective measure to implement the structural adjustment of supply, which conforms to the times. Firstly, basic features and design principles of the railway intelligent cold chain logistics system were described. Secondly, target functions and the system framework of the railway intelligent cold chain logistics were put forward, which takes information service as a foundation, management service as a guarantee, business capability as kernel and expansion capability as support. Subsequently, the technical approaches were studied at the hardware, processing and software levels. Finally, development strategies of the railway intelligent cold chain logistics were discussed, including optimizing the layout of infrastructure, improving the performance of equipment, extending the reach of services, deepening the cooperation of technologies and promoting the formulation of standards which provides feasible references for the railway cold chain logistics to explore modern business models. 展开更多
关键词 China Railway Cold Chain Logistics Intelligent Logistics System System Framework Scheme Design
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Quantitative measurement of the charge carrier concentration using dielectric force microscopy
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作者 赖君奇 陈博文 +4 位作者 邢志伟 李雪飞 陆书龙 陈琪 陈立桅 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第3期449-455,共7页
The charge carrier concentration profile is a critical factor that determines semiconducting material properties and device performance.Dielectric force microscopy(DFM)has been previously developed to map charge carri... The charge carrier concentration profile is a critical factor that determines semiconducting material properties and device performance.Dielectric force microscopy(DFM)has been previously developed to map charge carrier concentrations with nanometer-scale spatial resolution.However,it is challenging to quantitatively obtain the charge carrier concentration,since the dielectric force is also affected by the mobility.Here,we quantitative measured the charge carrier concentration at the saturation mobility regime via the rectification effect-dependent gating ratio of DFM.By measuring a series of n-type GaAs and GaN thin films with mobility in the saturation regime,we confirmed the decreased DFM-measured gating ratio with increasing electron concentration.Combined with numerical simulation to calibrate the tip–sample geometry-induced systematic error,the quantitative correlation between the DFM-measured gating ratio and the electron concentration has been established,where the extracted electron concentration presents high accuracy in the range of 4×10^(16)–1×10^(18)cm^(-3).We expect the quantitative DFM to find broad applications in characterizing the charge carrier transport properties of various semiconducting materials and devices. 展开更多
关键词 dielectric force microscopy charge carrier concentration quantitative measurement numerical simulation
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3D printed silicon-based micro-lattices with ultrahigh areal/gravimetric capacities and robust structural stability for lithium-ion batteries
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作者 Jie Fu Dong Wang +7 位作者 Yan li Xianzheng liu Rui Zhang Zhiyuan liu Pengdong liu lijuan Zhang xuefei li Guangwu Wen 《Nano Research》 SCIE EI CSCD 2024年第4期2693-2703,共11页
Nanostructured silicon anodes have shown extraordinary lithium storage properties for lithium-ion batteries(LIBs)but are usually achieved at low areal loadings(<1.5 mg·cm^(-2))with low areal capacity.Sustainin... Nanostructured silicon anodes have shown extraordinary lithium storage properties for lithium-ion batteries(LIBs)but are usually achieved at low areal loadings(<1.5 mg·cm^(-2))with low areal capacity.Sustaining sound electrochemical performance at high loading requires proportionally higher ion/electron currents and robust structural stability in the thicker electrode.Herein,we report a three-dimensional(3D)printed silicon-graphene-carbon nanotube(3D-Si/G/C)electrode for simultaneously achieving ultrahigh areal/gravimetric capacities at high mass loading.The periodically arranged vertical channels and hierarchically porous filaments facilitate sufficient electrolyte infiltration and rapid ion diffusion,and the carbonaceous network provides excellent electron transport properties and mechanical integrity,thus endowing the printed 3D-Si/G/C electrode with fast electrochemical reaction kinetics and reversibility at high mass loading.Consequently,the 3D-Si/G/C with high areal mass loading of 12.9 mg·cm^(-2) exhibits excellent areal capacity of 12.8 mAh·cm^(-2) and specific capacity of 1007 mAh·g^(-1),respectively.In-situ optical microscope and ex-situ scanning electron microscope(SEM)confirm that the hierarchically porous filaments with interconnected carbon skeletons effectively suppress the volume change of silicon and maintain stable micro-lattice architecture.A 3D printed 3D-Si/G/C-1||3D-LiFePO_(4)/G full cell holds excellent cyclic stability(capacity retention rate of 78%after 50 cycles)with an initial Coulombic efficiency(ICE)of 96%.This work validates the feasibility of 3D printing on constructing high mass loading silicon anode for practical high energy-density LIBs. 展开更多
关键词 silicon anode areal capacity three-dimensional(3D)printing lithium-ion batteries
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基于淋巴管系统在免疫调节中的作用探讨新冠病毒致肺损伤的机制及中药干预作用 被引量:6
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作者 梁倩倩 陈伟 +11 位作者 徐浩 王腾腾 黄怡 石怡 陈锦漫 陈绍华 姚妙恩 鲍嘉敏 庄紫欣 李雪菲 施杞 王拥军 《世界科学技术-中医药现代化》 CSCD 北大核心 2020年第2期270-277,共8页
新型冠状病毒肺炎所产生的炎性渗出,炎症风暴导致急性肺损伤,大量免疫细胞和组织液聚集肺脏,造成患者通气功能障碍,呼吸窘迫,甚至呼吸衰竭而死亡。调节免疫反应和减少肺组织渗出对控制该病的进展及促进后期康复至关重要。淋巴管系统具... 新型冠状病毒肺炎所产生的炎性渗出,炎症风暴导致急性肺损伤,大量免疫细胞和组织液聚集肺脏,造成患者通气功能障碍,呼吸窘迫,甚至呼吸衰竭而死亡。调节免疫反应和减少肺组织渗出对控制该病的进展及促进后期康复至关重要。淋巴管系统具有免疫监视、免疫捕获和维持组织间液平衡的作用,在急性炎症反应过程发挥重要作用。本文综述淋巴管系统在肺部的分布、生理功能及其在急性肺损伤过程中的作用,结合本团队研究成果,探讨淋巴管系统在新型冠状病毒肺炎病理进程中的作用和机制,以及中医药疗法机制,为临床新型冠状病毒肺炎的治疗提供新思路和潜在治疗方案。 展开更多
关键词 新型冠状病毒肺炎 淋巴管系统 急性免疫反应 急性肺损伤 中医药治疗
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Exploiting Geo-Social Correlations to Improve Pairwise Ranking for Point-of-Interest Recommendation 被引量:9
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作者 Rong Gao Jing li +4 位作者 Bo Du xuefei li Jun Chang Chengfang Song Donghua liu 《China Communications》 SCIE CSCD 2018年第7期180-201,共22页
Recently, as location-based social network(LBSN) rapidly grow, point-of-interest(POI) recommendation has become an important way to help people locate interesting places. Nowadays, there have been deep studies conduct... Recently, as location-based social network(LBSN) rapidly grow, point-of-interest(POI) recommendation has become an important way to help people locate interesting places. Nowadays, there have been deep studies conducted on the geographical and social influence in the point-of-interest recommendation model based on the rating prediction. The fact is, however, relying solely on the rating fails to reflect the user's preferences very accurately, because the users are most concerned with the list of ranked point-of-interests(POIs) on the actual output of recommender systems. In this paper, we propose a co-pairwise ranking model called Geo-Social Bayesian Personalized Ranking model(GSBPR), which is based on the pairwise ranking with the exploiting geo-social correlations by incorporating the method of ranking learning into the process of POI recommendation. In this model, we develop a novel BPR pairwise ranking assumption by injecting users' geo-social preference. Based on this assumption, the POI recommendation model is reformulated by a three-level joint pairwise ranking model. And the experimental results based on real datasets show that the proposed method in this paper enjoys better recommendation performance compared to other state-of-the-art POI recommendation models. 展开更多
关键词 评价模型 社会网络 GEO 关联 夏威夷 利用评价 GEO 食品
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Outcome comparison of pyrotinib with current standard of care in the second/third line setting in advanced non-small cell lung cancer patients with HER2 mutation 被引量:1
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作者 Shiqi Mao libo Luo +18 位作者 Shuo Yang Yan Wang Fei Zhou Jia Yu Bin Chen Guanghui Gao xuefei li Chao Zhao Lei Cheng Yiwei liu Wanying Wang Keyi Jia Chuchu Shao Xinyu liu Xiaoxia Chen Chunxia Su Caicun Zhou Fengying Wu Shengxiang Ren 《Chinese Medical Journal》 SCIE CAS CSCD 2023年第7期848-850,共3页
To the Editor:In recent years,impressive outcomes have been achieved in patients harboring human epidermal growth factor receptor 2(HER2)mutations,which accounts for 1%to 4%of cases in non-small cell lung cancer(NSCLC).
关键词 PATIENTS LUNG cancer
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Interfacial dynamics of GaP/Si(100) heterostructure grown by molecular beam epitaxy
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作者 Tieshi Wei xuefei li +4 位作者 Zhiyun li Wenxian Yang Yuanyuan Wu Zhiwei Xing Shulong Lu 《Journal of Semiconductors》 EI CAS CSCD 2022年第12期32-38,共7页
The atomic structure and surface chemistry of GaP/Si(100)heterostructure with different pre-layers grown by molecu-lar beam epitaxy are studied.It is found that GaP epilayer with Ga-riched pre-layers on Si(100)substra... The atomic structure and surface chemistry of GaP/Si(100)heterostructure with different pre-layers grown by molecu-lar beam epitaxy are studied.It is found that GaP epilayer with Ga-riched pre-layers on Si(100)substrate has regular surface mor-phology and stoichiometric abrupt heterointerfaces from atomic force microscopes(AFMs)and spherical aberration-corrected transmission electron microscopes(ACTEMs).The interfacial dynamics of GaP/Si(100)heterostructure is investigated by X-ray photoelectron spectroscopy(XPS)equipped with an Ar gas cluster ion beam,indicating that Ga pre-layers can lower the inter-face formation energy and the bond that is formed is more stable.These results suggest that Ga-riched pre-layers are more con-ducive to the GaP nucleation as well as the epitaxial growth of GaP material on Si(100)substrate. 展开更多
关键词 XPS interfacial dynamics GaP/Si(100)heterostructure MBE
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Application of Bionic Tribology in Water-Lubricated Bearing:A Review 被引量:3
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作者 xuefei li Zhiwei Guo +1 位作者 Qiren Huang Chengqing Yuan 《Journal of Bionic Engineering》 SCIE EI CSCD 2022年第4期902-934,共33页
Water-lubricated bearing has become the development trend in the future because of its economy and environmental friendliness.The poor friction performance under low speed and heavy load seriously limits the populariz... Water-lubricated bearing has become the development trend in the future because of its economy and environmental friendliness.The poor friction performance under low speed and heavy load seriously limits the popularization and application of water-lubricated bearings.Learning from nature,the phenomenon of low friction and wear in nature has aroused great interest of scientists,and a lot of research has been carried out from mechanism analysis to bionic application.In this review,our purpose is to provide guiding methods and analysis basis for the bionic design and theoretical research of anti-friction and anti-wear of water-lubricated bearings.The development of water-lubricated bearing materials are described.Some typical examples of natural friction reduction and drag reduction are introduced in detail,and several representative preparation methods are listed.Finally,the application status of bionic tribology in water-lubricated bearings is summarized,and the future development direction of water-lubricated bearings is prospected. 展开更多
关键词 Water-lubricated bearing Bionic tribology Bearing material FRICTION WEAR
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Accuracy and reliability of orthogonal polynomials in representing corneal topography
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作者 Junjie Wang xuefei li +7 位作者 Zheng Wang Pinakin G.Davey Yiyu li Lanting Yang Mao lin Xiaobo Zheng Fangjun Bao Ahmed Elsheikh 《Medicine in Novel Technology and Devices》 2022年第3期124-133,共10页
Fitting of corneal topography data to analytical surfaces has been necessary in many clinical and experimental applications,yet absolute superiority of fitting methods was still unclear,and their overfitting risks wer... Fitting of corneal topography data to analytical surfaces has been necessary in many clinical and experimental applications,yet absolute superiority of fitting methods was still unclear,and their overfitting risks were not well studied.This study aimed to evaluate the accuracy and reliability of orthogonal polynomials as fitting routines to represent corneal topography.Four orthogonal polynomials,namely,Zernike polynomials(ZPs),pseudo-Zernike polynomials(PZPs),Gaussian-Hermite polynomials(GHPs)and Orthogonal Fourier-Mellin polynomials(OFMPs),were employed to fit anterior and posterior corneal topographies collected from 200 healthy and 174 keratoconic eyes using Pentacam topographer.The fitting performance of these polynomials were compared,and the potential overfitting risks were assessed through a prediction exercise.The results showed that,except for low orders,the fitting performance differed little among polynomials with orders10 regarding surface reconstruction(RMSEs~0.3μm).Anterior surfaces of normal corneas were fitted more efficiently,followed by those of keratoconic corneas,then posterior corneal surfaces.The results,however,revealed an alarming fact that all polynomials tended to overfit the data beyond certain orders.GHPs,closely followed by ZPs,were the most robust in predicting unmeasured surface locations;while PZPs and especially OFMPs overfitted the surfaces drastically.Order 10 appeared to be optimum for corneal surfaces with 10-mm diameter,ensuring accurate reconstruction and avoiding overfitting.The optimum order however varied with topography diameters and data resolutions.The study concluded that continuing to use ZPs as fitting routine for most topography maps,or using GHPs instead,remains a good choice.Choosing polynomial orders close to the topography diameters(millimeters)is generally suggested to ensure both reconstruction accuracy and prediction reliability and avoid overfitting for both normal and complex(e.g.,keratoconic)corneal surfaces. 展开更多
关键词 Corneal topography Orthogonal polynomials Optimum order OVERFITTING PENTACAM
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Insight into the Lubrication Performance of Biomimetic Porous Structure Material for Water-lubricated Bearings 被引量:1
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作者 xuefei li Zhiwei Guo +1 位作者 Qiren Huang Chengqing Yuan 《Journal of Bionic Engineering》 SCIE EI CSCD 2023年第5期1905-1916,共12页
Water-lubricated bearings have great advantages in the application of ship tail bearings due to the characteristics of green,pollution-free,and sustainable.However,the poor wettability of water-lubricated materials,as... Water-lubricated bearings have great advantages in the application of ship tail bearings due to the characteristics of green,pollution-free,and sustainable.However,the poor wettability of water-lubricated materials,as well as the low viscosity and poor load-carrying capacity of water,resulting in poor lubricating film integrity and short material service life under low-speed,heavy-load,start-stop conditions,which limits its application.To study the relationship between wettability and lubrication state and improve the lubrication performance of Si_(3)N_(4) under water lubrication conditions,the characteristic parameters that determine the hydrophilicity of Sphagnum were detected and extracted,and the bionic Si_(3)N_(4) model was established using Material Studio.Then,the molecular dynamic behavior and tribological properties of different Si_(3)N_(4) models were simulated and analyzed.Pore structure affects the spreading and storage of water on the material surface and changes the wettability of the material.Under the condition of water lubrication,better wettability and water storage promote the formation of water film,effectively improve the lubrication state of the material,and improve its bearing performance. 展开更多
关键词 Molecular dynamic Water-lubricated bearing WETTABILITY FRICTION
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Carbon fluxes and soil carbon dynamics along a gradient of biogeomorphic succession in alpine wetlands of Tibetan Plateau 被引量:1
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作者 Hao Wang lingfei Yu +5 位作者 litong Chen Zhenhua Zhang xuefei li Naishen liang Changhui Peng Jin-Sheng He 《Fundamental Research》 CAS CSCD 2023年第2期151-159,共9页
Hydrological changes under climate warming drive the biogeomorphic succession of wetlands and may trigger substantial carbon loss from the carbon-rich ecosystems.Although many studies have explored the responses of we... Hydrological changes under climate warming drive the biogeomorphic succession of wetlands and may trigger substantial carbon loss from the carbon-rich ecosystems.Although many studies have explored the responses of wetland carbon emissions to short-term hydrological change,it remains poorly understood how the carbon cycle evolves with hydrology-driven wetland succession.Here,we used a space-for-time approach across hydrological gradients on the Tibetan Plateau to examine the dynamics of ecosystem carbon fluxes(carbon dioxide(CO_(2))and methane(CH4))and soil organic carbon pools during alpine wetland succession.We found that the succession from mesic meadow to fen changed the seasonality of both CO_(2) and CH4 fluxes,which was related to the shift in plant community composition,enhanced regulation of soil hydrology and increasing contribution of spring-thaw emission.The paludification caused a switch from net uptake of gaseous carbon to net release on an annual timescale but produced a large accumulation of soil organic carbon.We attempted to attribute the paradox between evidence from the carbon fluxes and pools to the lateral carbon input and the systematic changes of historical climate,given that the wetlands are spatially low-lying with strong temporal climate-carbon cycle interactions.These findings demonstrate a systematic change in the carbon cycle with succession and suggest that biogeomorphic succession and lateral carbon flows are both important for understanding the long-term dynamics of wetland carbon footprints. 展开更多
关键词 Carbon dioxide METHANE Soil organic carbon Climate change Hydrological change
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食用菌病毒的研究进展 被引量:9
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作者 李雪飞 宋冰 李玉 《微生物学报》 CAS CSCD 北大核心 2019年第10期1841-1854,共14页
病毒是引起食用菌发生病害的重要病原之一,由于其具有潜隐性、不易辨认的特点,因而难以被人们所察觉,一旦发病就难以控制。在食用菌研究领域中,食用菌病毒使食用菌产量严重下降,引起的病害越来越受人们的重视,逐步成为该领域的研究热点... 病毒是引起食用菌发生病害的重要病原之一,由于其具有潜隐性、不易辨认的特点,因而难以被人们所察觉,一旦发病就难以控制。在食用菌研究领域中,食用菌病毒使食用菌产量严重下降,引起的病害越来越受人们的重视,逐步成为该领域的研究热点。因此,本文主要针对食用菌病毒的结构与分类、危害、传播方式、检测方法以及食用菌病毒的脱毒技术等方面进行了综述,并对其存在的问题和前景进行了展望。这为食用菌病毒的检测、脱毒和无毒菌种的生产提供了理论依据,并为食用菌病毒的深入研究提供参考。 展开更多
关键词 食用菌病毒 结构与分类 危害 检测方法 脱毒
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以非天然核酸为遗传物质的人工生命构建 被引量:1
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作者 白艳芬 聂朋 +8 位作者 熊成鹤 温骏林 甘海云 马晴 胡政 李雪飞 于涛 黄建东 梅辉 《科学通报》 EI CAS CSCD 北大核心 2021年第3期347-355,共9页
合成生物学/工程生物学通过设计、搭建生物部件甚至生物系统来构建具有新功能的人工生命.其研究内容主要分为3个层次:(1)将现有的天然生物模块进行设计和组装,构建不同于天然存在的调控网络,从而实现新功能;(2)通过人工基因组DNA的全合... 合成生物学/工程生物学通过设计、搭建生物部件甚至生物系统来构建具有新功能的人工生命.其研究内容主要分为3个层次:(1)将现有的天然生物模块进行设计和组装,构建不同于天然存在的调控网络,从而实现新功能;(2)通过人工基因组DNA的全合成进行新生命的构建;(3)通过化学合成部件(修饰核酸、蛋白质、脂类等)创建全新的生物系统乃至生命体.第3个层次的研究也称为化学合成生物学,本文主要集中讨论化学合成生物学中将非天然核酸替代DNA作为遗传物质从而构建人工生命的研究,简要介绍了非天然核酸化学修饰对其遗传物质功能的影响,及以其为基础的人工生命构建的研究现状.这将为我们探讨生命起源、进化甚至外星生命等问题提供新的思路. 展开更多
关键词 合成生物学 非天然核酸 遗传物质 人工生命 新生命形式
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钴60诱变选育平菇新菌株的研究 被引量:8
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作者 宋冰 李雪飞 +3 位作者 史泽宇 李长田 付永平 李玉 《微生物学报》 CAS CSCD 北大核心 2019年第11期2155-2164,共10页
【目的】利用60Co-γ射线诱变平菇原生质体创制平菇新种质。【方法】通过3个剂量的60Co-γ射线辐照处理平菇原生质体悬浮液,统计不同剂量的致死率,利用拮抗试验、SSR分子标记筛选突变菌株,通过出菇试验筛选优良的平菇新菌株。【结果】... 【目的】利用60Co-γ射线诱变平菇原生质体创制平菇新种质。【方法】通过3个剂量的60Co-γ射线辐照处理平菇原生质体悬浮液,统计不同剂量的致死率,利用拮抗试验、SSR分子标记筛选突变菌株,通过出菇试验筛选优良的平菇新菌株。【结果】平菇原生质体在0.9 KGy的诱变处理下致死率为0%,在1.2KGy的诱变处理下菌株致死率63.33%,在1.5KGy的诱变处理下菌株致死率为76.67%。经拮抗试验和SSR分子标记筛选,获得了8株突变菌株,出菇试验结果表明7个突变菌株产量和生物学效率均有不同程度的降低,菌盖颜色也略有变化,其中突变菌株1.5-P4的产量较对照降低了41.92%;而突变菌株1.2-P1为高产菌株,其产量达437.95±12.22 g/袋,较对照菌株提高了9.76%,生物学效率较CK提高了10.38%。【结论】利用60Co-γ射线诱变育种技术得到了1个性状较为优良的平菇新菌株,这为其他食药用菌诱变育种研究提供了参考。 展开更多
关键词 平菇 钴60 诱变 SSR 高产菌株
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