The Doppler weather radar fault judging system and remote monitoring platform were introduced.Through the real-time scanning of radar alarm information coding,the platform can realize dynamic monitoring and real-time ...The Doppler weather radar fault judging system and remote monitoring platform were introduced.Through the real-time scanning of radar alarm information coding,the platform can realize dynamic monitoring and real-time alarm of Doppler radar equipment components,so as to improve the reliability of equipment operation,and truly realize"unattended"remote monitoring.展开更多
The oxygen reduction reaction （ORR） and oxygen evolution reaction （OER） are crucial processes for energy conversion/storage systems, such as fuel cells, metal-air batteries, and water splitting. However, both reac...The oxygen reduction reaction （ORR） and oxygen evolution reaction （OER） are crucial processes for energy conversion/storage systems, such as fuel cells, metal-air batteries, and water splitting. However, both reactions are severely restricted by their sluggish kinetics, thus requiring highly active, cost-effective, and durable electrocatalysts. Herein, we develop novel bifunctional nanocatalysts through surface nanoengineering of dealloying-driven nanoporous gold （NPG）. Pd overlayers were precisely deposited onto the NPG ligament surface by epitaxial layer-by-layer growth. More importantly, the obtained NPG-Pd overlayer nanocatalysts exhibit remarkably enhanced electrocatalytic activities toward both the ORR and OER in alkaline media, benchmarked against a state- of-the-art Pt/C catalyst. The improved electrocatalytic performance is rationalized by the unique three-dimensional nanoarchitecture of NPG, enhanced Pd utilization efficiency from precise control of the Pd overlayers, and change in electronic structure, as revealed by density functional theory calculations.展开更多
The development of nanomedicine has recently achieved several breakthroughs in the field of cancer treatment;however,biocompatibility and targeted penetration of these nanomaterials remain as limitations,which lead to...The development of nanomedicine has recently achieved several breakthroughs in the field of cancer treatment;however,biocompatibility and targeted penetration of these nanomaterials remain as limitations,which lead to serious side effects and significantly narrow the scope of their application.The self-assembly of intermediate filaments with arginine-glycine-aspartate(RGD)peptide(RGDIFP)was triggered by the hydrophobic cationic molecule 7-amino actinomycin D(7-AAD)to synthesize a bifunctional nanoparticle that could serve as a fluorescent imaging probe to visualize tumor treatment.The designed RGD-IFP peptide possessed the ability to encapsulate 7-AAD molecules through the formation of hydrogen bonds and hydrophobic interactions by a one-step method.This fluorescent nanoprobe with RGD peptide could be targeted for delivery into tumor cells and released in acidic environments such as endosomes/lysosomes,ultimately inducing cytotoxicity by arresting tumor cell cycling with inserted DNA.It is noteworthy that the RGD-IFP/7-AAD nanoprobe tail-vein injection approach demonstrated not only high tumor-targeted imaging potential,but also potent antitumor therapeutic effects in vivo.The proposed strategy may be used in peptide-driven bifunctional nanoparticles for precise imaging and cancer therapy.展开更多
文摘The Doppler weather radar fault judging system and remote monitoring platform were introduced.Through the real-time scanning of radar alarm information coding,the platform can realize dynamic monitoring and real-time alarm of Doppler radar equipment components,so as to improve the reliability of equipment operation,and truly realize"unattended"remote monitoring.
基金The authors gratefully acknowledge financial support by the National Basic Research Program of China （No. 2012CB932800）, National Natural Science Foundation of China （Nos. 51371106 and 51222202）, and Young Tip-top Talent Support Project （the Organization Department of the Central Committee of the CPC）. The Institute of Materials of Ruhr University Bochum （Germany） is acknowledged for the support of SEM and TEM characterization. This work also made use of the resources of the Center of Electron Microscopy of Zhejiang University.
文摘The oxygen reduction reaction （ORR） and oxygen evolution reaction （OER） are crucial processes for energy conversion/storage systems, such as fuel cells, metal-air batteries, and water splitting. However, both reactions are severely restricted by their sluggish kinetics, thus requiring highly active, cost-effective, and durable electrocatalysts. Herein, we develop novel bifunctional nanocatalysts through surface nanoengineering of dealloying-driven nanoporous gold （NPG）. Pd overlayers were precisely deposited onto the NPG ligament surface by epitaxial layer-by-layer growth. More importantly, the obtained NPG-Pd overlayer nanocatalysts exhibit remarkably enhanced electrocatalytic activities toward both the ORR and OER in alkaline media, benchmarked against a state- of-the-art Pt/C catalyst. The improved electrocatalytic performance is rationalized by the unique three-dimensional nanoarchitecture of NPG, enhanced Pd utilization efficiency from precise control of the Pd overlayers, and change in electronic structure, as revealed by density functional theory calculations.
基金supported by the National Natural Science Foundation of China(No.81603016,81773624,81900453)the Natural Science Foundation of Jiangsu Province(No.BK20160706,BE2017746,China)the National Science and Technology Major Project(2018ZX09301026-005,2020ZX09201015,China)。
文摘The development of nanomedicine has recently achieved several breakthroughs in the field of cancer treatment;however,biocompatibility and targeted penetration of these nanomaterials remain as limitations,which lead to serious side effects and significantly narrow the scope of their application.The self-assembly of intermediate filaments with arginine-glycine-aspartate(RGD)peptide(RGDIFP)was triggered by the hydrophobic cationic molecule 7-amino actinomycin D(7-AAD)to synthesize a bifunctional nanoparticle that could serve as a fluorescent imaging probe to visualize tumor treatment.The designed RGD-IFP peptide possessed the ability to encapsulate 7-AAD molecules through the formation of hydrogen bonds and hydrophobic interactions by a one-step method.This fluorescent nanoprobe with RGD peptide could be targeted for delivery into tumor cells and released in acidic environments such as endosomes/lysosomes,ultimately inducing cytotoxicity by arresting tumor cell cycling with inserted DNA.It is noteworthy that the RGD-IFP/7-AAD nanoprobe tail-vein injection approach demonstrated not only high tumor-targeted imaging potential,but also potent antitumor therapeutic effects in vivo.The proposed strategy may be used in peptide-driven bifunctional nanoparticles for precise imaging and cancer therapy.
