Objective:To analyze the effects of continuous self-management education on the selfcare ability and health behavior of patients with tumor through peripherally inserted central venous catheters(PICC).Methods:The peri...Objective:To analyze the effects of continuous self-management education on the selfcare ability and health behavior of patients with tumor through peripherally inserted central venous catheters(PICC).Methods:The period from August 2018 to August 2020 was used as the research time range,and the random number table method was used as the basis for grouping.80 patients with malignant tumors who regularly performed fixed catheter maintenance care in the PICC clinic of our hospital were admitted in the experimental group(given PICC specialist nursing,and implemented continuous self-management education),and 80 patients with PICC tube malignant tumors discharged from the superior hospital during this time range served as the control group(return to the original catheterization hospital from time to time or perform catheter maintenance care in the nursing clinic of our hospital).The self-care ability scores,health behavior scores,and complications during intubation between both groups were analyzed.Results:(1)There was no significant difference in self-care ability score and healthy behavior score between groups before the intervention,P>0.05;the self-care ability score and health behavior score of the research group were better than the control group after intervention,P<0.05;(2)After investigation,the incidence of complications in the research group(2.50%)was lower than that of the control group(10.00%),but there was no difference between the groups,P>0.05.Conclusion:Continuous self-management education has good effects on improving the self-care ability of tumor patients with PICC intubation.It can urge patients to maintain good health behaviors and reduce complications.It is worthy of promotion.展开更多
Development of high-performance microwave absorption materials(MAM)with stabilized magnetic properties at high temperatures is specifically essential but remains challenging.Moreover,the Snoke's limitation restrai...Development of high-performance microwave absorption materials(MAM)with stabilized magnetic properties at high temperatures is specifically essential but remains challenging.Moreover,the Snoke's limitation restrains the microwave absorption(MA)property of magnetic materials.Modulating alloy components is considered an effective way to solve the aforementioned problems.Herein,a hollow medium-entropy FeCoNiAl alloy with a stable magnetic property is prepared via simple spray-drying and two-step annealing for efficient MA.FeCoNiAl exhibited an ultrabroad effective absorption band(EAB)of 5.84 GHz(12.16–18 GHz)at a thickness of just 1.6 mm,revealing an excellent absorption capability.Furthermore,the MA mechanism of FeCoNiAl is comprehensively investigated via off-axis holography.Finally,the electromagnetic properties,antioxidant properties,and residual magnetism at high temperatures of FeCoNiAl alloys are summarized in detail,providing new insights into the preparation of MAM operating at elevated temperatures.展开更多
The mapping of DNA cytosine modifications is crucial for understanding the dynamic landscape of epigenetic regulation.While bisulfite sequencing has been the gold standard for decades,it suffers from limitations such ...The mapping of DNA cytosine modifications is crucial for understanding the dynamic landscape of epigenetic regulation.While bisulfite sequencing has been the gold standard for decades,it suffers from limitations such as DNA degradation and low library quality due to harsh chemical treatment.In recent years,bisulfite-free methods have emerged as promising alternatives for detecting and quantifying DNA cytosine modifications.These methods employ enzymatic and chemical strategies to investigate cytosine modifications without the need for bisulfite treatment.This review provides an overview of the historical context of bisulfite-based methods and presents the current landscape of bisulfite-free methods.The advantages and limitations of each approach are discussed,along with insights into their applications.Furthermore,the review explores the existing challenges in the field and presents future perspectives and potential directions for advancing bisulfite-free mapping methods.The continued progress in bisulfite-free techniques holds great promise for unraveling the intricate nature of DNA cytosine modifications and their functional implications in diverse biological processes and diseases.展开更多
Flowering time is a trait vital to the adaptation of flowering plants to different environments. Here, we report that CCT domain genes play an important role in flowering in maize （Zea mays L.）. Among the 53 CCT fam...Flowering time is a trait vital to the adaptation of flowering plants to different environments. Here, we report that CCT domain genes play an important role in flowering in maize （Zea mays L.）. Among the 53 CCT family genes we identified in maize, 28 were located in flowering time quantitative trait locus regions and 15 were significantly associated with flowering time, based on candidate-gene association mapping analysis. Furthermore, a CCT gene named ZmCOL3 was shown to be a repressor of flowering. Overexpressing ZmCOL3 delayed flowering time by approximately 4 d, in either long-day or short-day conditions. The absence of one cytosine in the ZmCOL3 3＇UTR and the presence of a 551 bp fragment in the promoter region are likely the causal polymorphisms contributing to the maize adaptation from tropical to temperate regions. We propose a modified model of the maize photoperiod pathway, wherein ZmCOL3 acts as an inhibitor of flowering either by transactivating transcription of ZmCCT, one of the key genes regulating maize flowering, or by interfering with the circadian clock.展开更多
文摘Objective:To analyze the effects of continuous self-management education on the selfcare ability and health behavior of patients with tumor through peripherally inserted central venous catheters(PICC).Methods:The period from August 2018 to August 2020 was used as the research time range,and the random number table method was used as the basis for grouping.80 patients with malignant tumors who regularly performed fixed catheter maintenance care in the PICC clinic of our hospital were admitted in the experimental group(given PICC specialist nursing,and implemented continuous self-management education),and 80 patients with PICC tube malignant tumors discharged from the superior hospital during this time range served as the control group(return to the original catheterization hospital from time to time or perform catheter maintenance care in the nursing clinic of our hospital).The self-care ability scores,health behavior scores,and complications during intubation between both groups were analyzed.Results:(1)There was no significant difference in self-care ability score and healthy behavior score between groups before the intervention,P>0.05;the self-care ability score and health behavior score of the research group were better than the control group after intervention,P<0.05;(2)After investigation,the incidence of complications in the research group(2.50%)was lower than that of the control group(10.00%),but there was no difference between the groups,P>0.05.Conclusion:Continuous self-management education has good effects on improving the self-care ability of tumor patients with PICC intubation.It can urge patients to maintain good health behaviors and reduce complications.It is worthy of promotion.
基金supported by the Ministry of Science and Technology of China(No.2021YFA1200600)the National Natural Science Foundation of China(Nos.52231007,12327804,22088101,51725101,and T2321003)+4 种基金the Science and Technology Research Project of Jiangxi Provincial Department of Education(No.GJJ200338)Key Research Project of Zhejiang Lab(No.2021PE0AC02)the“Chenguang Program”by Shanghai Education Development Foundation and Shanghai Municipal Education Commission(No.21CGA04)sponsored by Shanghai Sailing Program(No.21YF1401800)the Fund of Science and Technology on Surface Physics and Chemistry Laboratory(No.JCKYS2023120201).
文摘Development of high-performance microwave absorption materials(MAM)with stabilized magnetic properties at high temperatures is specifically essential but remains challenging.Moreover,the Snoke's limitation restrains the microwave absorption(MA)property of magnetic materials.Modulating alloy components is considered an effective way to solve the aforementioned problems.Herein,a hollow medium-entropy FeCoNiAl alloy with a stable magnetic property is prepared via simple spray-drying and two-step annealing for efficient MA.FeCoNiAl exhibited an ultrabroad effective absorption band(EAB)of 5.84 GHz(12.16–18 GHz)at a thickness of just 1.6 mm,revealing an excellent absorption capability.Furthermore,the MA mechanism of FeCoNiAl is comprehensively investigated via off-axis holography.Finally,the electromagnetic properties,antioxidant properties,and residual magnetism at high temperatures of FeCoNiAl alloys are summarized in detail,providing new insights into the preparation of MAM operating at elevated temperatures.
基金supported by the start-up funding from Wuhan UniversityFundamental Research Funds for the Central Universities(2042023kf0118)。
文摘The mapping of DNA cytosine modifications is crucial for understanding the dynamic landscape of epigenetic regulation.While bisulfite sequencing has been the gold standard for decades,it suffers from limitations such as DNA degradation and low library quality due to harsh chemical treatment.In recent years,bisulfite-free methods have emerged as promising alternatives for detecting and quantifying DNA cytosine modifications.These methods employ enzymatic and chemical strategies to investigate cytosine modifications without the need for bisulfite treatment.This review provides an overview of the historical context of bisulfite-based methods and presents the current landscape of bisulfite-free methods.The advantages and limitations of each approach are discussed,along with insights into their applications.Furthermore,the review explores the existing challenges in the field and presents future perspectives and potential directions for advancing bisulfite-free mapping methods.The continued progress in bisulfite-free techniques holds great promise for unraveling the intricate nature of DNA cytosine modifications and their functional implications in diverse biological processes and diseases.
基金supported by the National Key Research and Development Program of China (2016YFD0101003)the National Natural Science Foundation of China (31525017, 31771879)+1 种基金Science and Technology Development Plan of Jilin Province (20160520060JH)Agricultural Science and Technology Innovation Program of Jilin Province (CXGC2017JQ014)
文摘Flowering time is a trait vital to the adaptation of flowering plants to different environments. Here, we report that CCT domain genes play an important role in flowering in maize （Zea mays L.）. Among the 53 CCT family genes we identified in maize, 28 were located in flowering time quantitative trait locus regions and 15 were significantly associated with flowering time, based on candidate-gene association mapping analysis. Furthermore, a CCT gene named ZmCOL3 was shown to be a repressor of flowering. Overexpressing ZmCOL3 delayed flowering time by approximately 4 d, in either long-day or short-day conditions. The absence of one cytosine in the ZmCOL3 3＇UTR and the presence of a 551 bp fragment in the promoter region are likely the causal polymorphisms contributing to the maize adaptation from tropical to temperate regions. We propose a modified model of the maize photoperiod pathway, wherein ZmCOL3 acts as an inhibitor of flowering either by transactivating transcription of ZmCCT, one of the key genes regulating maize flowering, or by interfering with the circadian clock.
