INTRODUCTIONIn order to study the relationship between oncogeneexpression and HCC generation,we observed theprecancerous hepatic GGT loci,IGF-Ⅱ,p53 andp21 expression during hepatocarcinogenesis of treeshrew induced b...INTRODUCTIONIn order to study the relationship between oncogeneexpression and HCC generation,we observed theprecancerous hepatic GGT loci,IGF-Ⅱ,p53 andp21 expression during hepatocarcinogenesis of treeshrew induced by hepatitis B virus (HBV) and/oraflatoxin B1 (AFB1).展开更多
研究旨在评估肥育猪日粮直链淀粉与支链淀粉比例(DAR)对机体健康和肉品质的影响。共选取杜×长×大猪48头(初始体重74.9±5.0 kg),随机分为两个处理组,分别为LR日粮组(DAR:12/88)和HR日粮组(DAR:30/70)。结果表明,HR组血浆...研究旨在评估肥育猪日粮直链淀粉与支链淀粉比例(DAR)对机体健康和肉品质的影响。共选取杜×长×大猪48头(初始体重74.9±5.0 kg),随机分为两个处理组,分别为LR日粮组(DAR:12/88)和HR日粮组(DAR:30/70)。结果表明,HR组血浆甘油三酯及胆固醇水平显著降低(P<0.05),肝脏脂肪含量显著减少(P<0.05)。HR日粮组有减少肌内脂肪含量的趋势(P=0.06),并显著增加了硬度(P<0.05),极显著增加了腰部眼肌面积(P<0.01)。并且,HR日粮组背最长肌My HC I水平显著降低(P<0.05),且My HC IIb基因表达水平显著提高(P<0.05)。HR日粮导致肝脏和背最长肌FAS3基因下调(P<0.05)。结果表明,HR日粮有利于降低肝脏和肌肉中的脂肪形成。展开更多
Kaposi＆#39;s sarcoma （KS） is a rare,malignant vascular.tumor of the skin,mucosa,and viscera with an increased incidence in human immunodeficiency virus （HIV）-positive patients.According to the clinical characteri...Kaposi＆#39;s sarcoma （KS） is a rare,malignant vascular.tumor of the skin,mucosa,and viscera with an increased incidence in human immunodeficiency virus （HIV）-positive patients.According to the clinical characteristics and the affected population,four clinical types of KS have been described successively：classic,endemic to Africa,acquired immunodeficiency syndrome （AIDS）-associated,and immunosuppression associated type.Bullous pemphigoid （BP） is an acquired autoimmune bullous skin disease that frequently occurs in the elderly and is characterized by intraepidermal blisters and immunoglobulin G （IgG） deposits on the basement membrane.A few cases of KS have occurred in immunosuppressed patients with BP.Here,we report a Chinese female patient diagnosed with immunosuppression associated KS that was induced by the short-term use of immunosuppressive agents for BP.We also present a review of the literature on immunosuppressed KS with BP and discuss the potential role of human herpesvirus-8 （HHV-8） in the pathogenic mechanism.展开更多
基金the National Natural Science Foundation of China,No.39260033.
文摘INTRODUCTIONIn order to study the relationship between oncogeneexpression and HCC generation,we observed theprecancerous hepatic GGT loci,IGF-Ⅱ,p53 andp21 expression during hepatocarcinogenesis of treeshrew induced by hepatitis B virus (HBV) and/oraflatoxin B1 (AFB1).
文摘研究旨在评估肥育猪日粮直链淀粉与支链淀粉比例(DAR)对机体健康和肉品质的影响。共选取杜×长×大猪48头(初始体重74.9±5.0 kg),随机分为两个处理组,分别为LR日粮组(DAR:12/88)和HR日粮组(DAR:30/70)。结果表明,HR组血浆甘油三酯及胆固醇水平显著降低(P<0.05),肝脏脂肪含量显著减少(P<0.05)。HR日粮组有减少肌内脂肪含量的趋势(P=0.06),并显著增加了硬度(P<0.05),极显著增加了腰部眼肌面积(P<0.01)。并且,HR日粮组背最长肌My HC I水平显著降低(P<0.05),且My HC IIb基因表达水平显著提高(P<0.05)。HR日粮导致肝脏和背最长肌FAS3基因下调(P<0.05)。结果表明,HR日粮有利于降低肝脏和肌肉中的脂肪形成。
文摘Kaposi＆#39;s sarcoma （KS） is a rare,malignant vascular.tumor of the skin,mucosa,and viscera with an increased incidence in human immunodeficiency virus （HIV）-positive patients.According to the clinical characteristics and the affected population,four clinical types of KS have been described successively：classic,endemic to Africa,acquired immunodeficiency syndrome （AIDS）-associated,and immunosuppression associated type.Bullous pemphigoid （BP） is an acquired autoimmune bullous skin disease that frequently occurs in the elderly and is characterized by intraepidermal blisters and immunoglobulin G （IgG） deposits on the basement membrane.A few cases of KS have occurred in immunosuppressed patients with BP.Here,we report a Chinese female patient diagnosed with immunosuppression associated KS that was induced by the short-term use of immunosuppressive agents for BP.We also present a review of the literature on immunosuppressed KS with BP and discuss the potential role of human herpesvirus-8 （HHV-8） in the pathogenic mechanism.
