Fidelity plays an important role in quantum information processing,which provides a basic scale for comparing two quantum states.At present,one of the most commonly used fidelities is Uhlmann-Jozsa(U-J)fidelity.Howeve...Fidelity plays an important role in quantum information processing,which provides a basic scale for comparing two quantum states.At present,one of the most commonly used fidelities is Uhlmann-Jozsa(U-J)fidelity.However,U-J fidelity needs to calculate the square root of the matrix,which is not trivial in the case of large or infinite density matrices.Moreover,U-J fidelity is a measure of overlap,which has limitations in some cases and cannot reflect the similarity between quantum states well.Therefore,a novel quantum fidelity measure called quantum Tanimoto coefficient(QTC)fidelity is proposed in this paper.Unlike other existing fidelities,QTC fidelity not only considers the overlap between quantum states,but also takes into account the separation between quantum states for the first time,which leads to a better performance of measure.Specifically,we discuss the properties of the proposed QTC fidelity.QTC fidelity is compared with some existing fidelities through specific examples,which reflects the effectiveness and advantages of QTC fidelity.In addition,based on the QTC fidelity,three discrimination coefficients d_(1)^(QTC),d_(2)^(QTC),and d_^(3)^(QTC)are defined to measure the difference between quantum states.It is proved that the discrimination coefficient d_(3)^(QTC)is a true metric.Finally,we apply the proposed QTC fidelity-based discrimination coefficients to measure the entanglement of quantum states to show their practicability.展开更多
The environmental characteristics of hypothermia and hypoxia exert great selective pressure on the energy metabolism of high-altitude animals,especially the ectotherms.Current research on energy-limited adaptation of ...The environmental characteristics of hypothermia and hypoxia exert great selective pressure on the energy metabolism of high-altitude animals,especially the ectotherms.Current research on energy-limited adaptation of high-altitude ectotherms has focused on energy expenditures.However,the mechanisms of increasing energy intake in high-altitude ectotherms have been studied rarely.In order to investigate the adaptation mechanism of the small intestine,the key part of energy acquisition for animals,to energy limitation at high altitude in ectotherms,the gut proteins of Phrynocephalus vlangalii from high-and low-altitude populations were compared using label free proteomics.GO enrichment and KEGG pathway analysis showed that proteins associated with energy intake,such as those involved in oxidation-reduction processes,glutathione metabolism,oxidoreductase activity,cofactor binding,catalytic activity and metabolic pathways,were significantly up-regulated in high-altitude populations;while proteins associated with energy expenditure,such as immune responses and processes,membrane attack complexes,natural killer pathway and other immune-related processes,were significantly down-regulated in expression.展开更多
Global climate change is a threat to animals in nearly all biomes and ecosystems, especially for ectotherm whose life activities highly depend on environmental thermal regime. Population genetic diversity which is ess...Global climate change is a threat to animals in nearly all biomes and ecosystems, especially for ectotherm whose life activities highly depend on environmental thermal regime. Population genetic diversity which is essential for adaptation to environmental change is a useful index for long-term species survival. In this paper, genetic diversity of eight Phrynocephalus forsythii population which distributed in Tarim Basin, China, were evaluated based on three mtDNA gene and its correlation with environment factors were investigated using RDA. Our result revealed that, the level of genetic diversity of P. forsythii populations was related to its location but there was no significant correlation between genetic distances and geographic distances in P. forsythii. However, we find that mtDNA of P. forsythii was subjected to selection pressure during evolution and population genetic diversity was significantly positively related to variation coefficient of rainfall(VCR) and altitude(AL), while significantly negatively related to longitude(N) and annual average temperature(AAT). Our result supported the previous prediction that excessive ambient heat is a threat to P. forsythii.展开更多
In our previous work, a series of polyethylenimine(PEI)-derived cation exchangers were synthesized using PEIgrafted resin FF-PEI-L740(ionic capacity, 740 mmol·L^-1) as the basic resin to study lysozyme adsorption...In our previous work, a series of polyethylenimine(PEI)-derived cation exchangers were synthesized using PEIgrafted resin FF-PEI-L740(ionic capacity, 740 mmol·L^-1) as the basic resin to study lysozyme adsorption and chromatographic behavior. It was found that the resin with an ionic capacity of 630 mmol·L^-1(FF-PEI-CR630)possessed high adsorption performance towards lysozyme at 0–100 mmol·L^-1 Na Cl. Therefore, in this work,FF-PEI-CR630 was selected to study the influences of pH and ionic strength(IS) on protein adsorption and chromatographic behavior towards lysozyme. The increase of lysozyme adsorption capacity in the pH range of 6 to 10 was observed. However, the uptake rate decreased in the pH range of 6 to 8 and then remained essentially unchanged from pH 8 to pH 10. Increasing IS led to decreased protein adsorption capacity and increased uptake rate in different pH ranges. Besides, FF-PEI-CR630 maintained dynamic binding capacity as high as over150 mg·ml^-1 at pH 8–10 without NaCl. The research has thus provided insight into the selection of proper pH and IS conditions for protein purification by using FF-PEI-CR630.展开更多
Speciation has never been directly observed in nature because it is a lengthy phenomenon.Although rare,ring species are an optimal natural example of speciation and can be identified through the assessment of the geog...Speciation has never been directly observed in nature because it is a lengthy phenomenon.Although rare,ring species are an optimal natural example of speciation and can be identified through the assessment of the geographical conditions of their potential habitat.Phrynocephalus forsythii is endemic to the Tarim Basin,which compnses the Taklamakan Desert and surrounded by mountains on three sides.This study aimed to determine whether P.forsythii had a ring-species-like divergence pattern through the characterization of the genetic features of 17 populations covering the major distribution of this species.Species distribution modelling revealed that P.forsythii had a continuous circular distribution around the Tarim Basin.Gene flow was observed in most adjacent populations except for two terminal populations of the ring,which exhibit the highest differentiation.Genetic distance and geographic distance were significantly correlated,indicating that the observed differentiation resulted from genetic variation gradually accumulating during population dispersion.Although our results do not definitively indicate that P.forsythii is a ring species,our results indicate a ring-shaped diversification This phenomenon elucidates the potential mechanism underlying speciation in the presence of gene flow,providing insight into this evolutionary process.展开更多
The gut microbiota has gained attention because of its importance in facilitating host survival and evolution.However,it is unclear whether gut microbial communities are determined by the host(heritable factor) or env...The gut microbiota has gained attention because of its importance in facilitating host survival and evolution.However,it is unclear whether gut microbial communities are determined by the host(heritable factor) or environment(environmental factor).In this study,we investigated the gut microbial communities and potential functional signatures of two sympatric species distributed along an elevation gradient,the toadheaded lizards Phrynocephalus axillaris and P.forsythii.Our results indicated that at high elevations,the gut microbial communities of P.axillaris and P.forsythii did not significantly differ,and the phylogenetic relationships of gut microbial communities contradicted their hosts.At low altitudes,the two lizards could be distinguished based on their significantly different gut microbial communities.Compared to low-altitude populations,Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis showed that at higher altitudes,energy metabolism,such as carbohydrate,lipid,and amino acids metabolism were higher in both lizards.While a larger number of pathogenic bacteria were found in the lowaltitude population of P.forsythii.This suggests that the convergence of gut microbiota of two lizards at highaltitude stem from environmental factors,as they were exposed to the same environmental stress,whereas the divergence at low-altitude stemmed from heritable factors,as they were exposed to different environmental stresses.These results provide a new perspective regarding whether heritable or environmental factors dominate the gut microbiota during exposure to environmental stress.展开更多
objective: to explore the effect of detail nursing intervention on headache and negative emotion in patients with subarachnoid hemorrhage. Methods: the clinical data of 100 cases of subarachnoid hemorrhage from Januar...objective: to explore the effect of detail nursing intervention on headache and negative emotion in patients with subarachnoid hemorrhage. Methods: the clinical data of 100 cases of subarachnoid hemorrhage from January 2015 to January 2017 of neurosurgery in our hospital were randomly divided into the control group and the experimental group, Detail nursing intervention in experimental group, Comparison of two groups of clinical nursing effects. Results the duration of hospitalization and headache in the experimental group were shorter than those in the control group. Fewer headaches than control group (P<0.05) Less headache than control group (p<0.05). Results: the results of SAS and SDS scores were significantly lower than those in the control group (p<0.05) after nursing in the experimental group. Conclusion: the patients with subarachnoid hemorrhage receive detailed nursing intervention;contribute to the alleviation of their headache symptoms, Relieves the patient of negative emotional problems.展开更多
The friction coefficient and wear rate of pretreated graphite with liquid nitrogen were obtained by using a ball-on-disk tester,and the wear of GCr15–graphite seal pairs with the low-temperature time-dependent pretre...The friction coefficient and wear rate of pretreated graphite with liquid nitrogen were obtained by using a ball-on-disk tester,and the wear of GCr15–graphite seal pairs with the low-temperature time-dependent pretreatment was discussed by comparing the wear morphology.The results show that liquid nitrogen pretreatment can affect the hardness and interlayer spacing of graphite.The range of the friction coefficients of pretreated graphite changes from 0.17 to 0.22.With the increase of liquid nitrogen pretreatment time,the wear mechanism of graphite would change from dominated three-body wear to adhesion wear.The experimental results of the mechanical seal with liquid nitrogen pretreatment show that the wear rate of stator is less than 0.00165 mm^(3)·N^(−1)·m^(−1),and the graphite shows a good low-temperature compatibility.展开更多
Establishment of vaginal immune defenses at the mucosal interface layer through gene vaccines promise to prevent infectious diseases among females.Mucosal barriers composed of a flowing mucus hydrogel and tightly conj...Establishment of vaginal immune defenses at the mucosal interface layer through gene vaccines promise to prevent infectious diseases among females.Mucosal barriers composed of a flowing mucus hydrogel and tightly conjugated epithelial cells(ECs),which represent the main technical difficulties for vaccine development,reside in the harsh,acidic human vaginal environment.Different from frequently employed viral vectors,two types of nonviral nanocarriers were designed to concurrently overcome the barriers and induce immune responses.Differing design concepts include the charge-reversal property(DRLS)to mimic a virus that uses any cells as factories,as well as the addition of a hyaluronic acid coating(HA/RLS)to directly target dendritic cells(DCs).With a suitable size and electrostatic neutrality,these two nanoparticles penetrate a mucus hydrogel with similar diffusivity.The DRLS system expressed a higher level of the carried human papillomavirus type 16 L1 gene compared to HA/RLS in vivo.Therefore it induced more robust mucosal,cellular,and humoral immune responses.Moreover,the DLRS applied to intravaginal immunization induced high IgA levels compared with intramuscularly injected DNA(naked),indicating timely protection against pathogens at the mucus layer.These findings also offer important approaches for the design and fabrication of nonviral gene vaccines in other mucosal systems.展开更多
The self-mixing interferometry(SMI)technique is an emerging sensing technology in microscale particle classification.However,due to the nature of the SMI effect raised by a microscattering particle,the signal analysis...The self-mixing interferometry(SMI)technique is an emerging sensing technology in microscale particle classification.However,due to the nature of the SMI effect raised by a microscattering particle,the signal analysis suffers from many problems compared with a macro target,such as lower signal-to-noise ratio(SNR),short transit time,and time-varying modulation strength.Therefore,the particle sizing measurement resolution is much lower than the one in typical displacement measurements.To solve these problems,in this paper,first,a theoretical model of the phase variation of a singleparticle SMI signal burst is demonstrated in detail.The relationship between the phase variation and the particle size is investigated,which predicts that phase observation could be another alternative for particle detection.Second,combined with continuous wavelet transform and Hilbert transform,a novel phase-unwrapping algorithm is proposed.This algorithm can implement not only efficient individual burst extraction from the noisy raw signal,but also precise phase calculation for particle sizing.The measurement shows good accuracy over a range from 100 nm to 6μm with our algorithm,proving that our algorithm enables a simple and reliable quantitative particle characteristics retrieval and analysis methodology for microscale particle detection in biomedical or laser manufacturing fields.展开更多
In order to enhance the stability of single-phase microgrid,virtual synchronous generator(VSG)control method is investigated in this paper.Its electromagnetic model and electromechanical model are established to illus...In order to enhance the stability of single-phase microgrid,virtual synchronous generator(VSG)control method is investigated in this paper.Its electromagnetic model and electromechanical model are established to illustrate the performance of VSG.Considering the 2 nd fluctuation of fundamental-frequency in the output power,an instantaneous power calculation strategy is proposed based on the intrinsic frequency of single-phase VSG.Besides,a virtual power calculation method is presented to achieve islanded/grid-connected seamless transition.Stability analysis and comparison simulation results demonstrate the correctness of the presented power calculation method.At last,the effectiveness of the proposed approach is verified by comparison experiments of islanded/gridconnected operations in a 500 VA single-phase inverter.展开更多
To search for potent insecticides targeting at ryanodine receptors(RyRs),a series of novel anthranilic diamides analogs containing 4-chlorine N-pyridylpyrazole were designed and synthesized.Their insecticidal activiti...To search for potent insecticides targeting at ryanodine receptors(RyRs),a series of novel anthranilic diamides analogs containing 4-chlorine N-pyridylpyrazole were designed and synthesized.Their insecticidal activities were evaluated and the preliminary struc ture-activity relationships(SARs)were discussed.The insecticidal results showed that some of the compounds(8a-8h,8m,8n)exhibited good larvicidal activities against oriental armyworm at 2.5 mg·L^(-1),and compound 8m possessed 60%insecticidal activityat 0.5 mg·L^(-1).For diamondback moth,8m exhibited better activity than Chlorantraniliprole at a hundred fold preference.展开更多
The interaction between the source and load converters in cascaded DC-DC converters may cause instability.Thus,improving the stability of cascaded DC-DC converters is important.To solve the above-mentioned problem,a f...The interaction between the source and load converters in cascaded DC-DC converters may cause instability.Thus,improving the stability of cascaded DC-DC converters is important.To solve the above-mentioned problem,a flowchart to improve the control method is established by calculating the eigenvalue sensitivity of a time-domain model of cascaded DC-DC converters.Further,an additional voltage-error mutual feedback control method is firstly proposed based on the flowchart provided in this study to improve the stability of cascaded DC-DC converters.Subsequently,the influence of the proposed mutual feedback control on the stability of cascaded DC-DC converters is analyzed.Finally,the effectiveness of the proposed control method is verified by simulation and experiment.展开更多
基金supported by the National Natural Science Foundation of China(62003280,61976120)Chongqing Talents:Exceptional Young Talents Project(cstc2022ycjh-bgzxm0070)+2 种基金Natural Science Foundation of Chongqing(2022NSCQ-MSX2993)Natural Science Key Foundation of Jiangsu Education Department(21KJA510004)Chongqing Overseas Scholars Innovation Program(cx2022024)。
文摘Fidelity plays an important role in quantum information processing,which provides a basic scale for comparing two quantum states.At present,one of the most commonly used fidelities is Uhlmann-Jozsa(U-J)fidelity.However,U-J fidelity needs to calculate the square root of the matrix,which is not trivial in the case of large or infinite density matrices.Moreover,U-J fidelity is a measure of overlap,which has limitations in some cases and cannot reflect the similarity between quantum states well.Therefore,a novel quantum fidelity measure called quantum Tanimoto coefficient(QTC)fidelity is proposed in this paper.Unlike other existing fidelities,QTC fidelity not only considers the overlap between quantum states,but also takes into account the separation between quantum states for the first time,which leads to a better performance of measure.Specifically,we discuss the properties of the proposed QTC fidelity.QTC fidelity is compared with some existing fidelities through specific examples,which reflects the effectiveness and advantages of QTC fidelity.In addition,based on the QTC fidelity,three discrimination coefficients d_(1)^(QTC),d_(2)^(QTC),and d_^(3)^(QTC)are defined to measure the difference between quantum states.It is proved that the discrimination coefficient d_(3)^(QTC)is a true metric.Finally,we apply the proposed QTC fidelity-based discrimination coefficients to measure the entanglement of quantum states to show their practicability.
基金supported by the National Natural Science Foundation of China(Nos.31471988 and 31200287)。
文摘The environmental characteristics of hypothermia and hypoxia exert great selective pressure on the energy metabolism of high-altitude animals,especially the ectotherms.Current research on energy-limited adaptation of high-altitude ectotherms has focused on energy expenditures.However,the mechanisms of increasing energy intake in high-altitude ectotherms have been studied rarely.In order to investigate the adaptation mechanism of the small intestine,the key part of energy acquisition for animals,to energy limitation at high altitude in ectotherms,the gut proteins of Phrynocephalus vlangalii from high-and low-altitude populations were compared using label free proteomics.GO enrichment and KEGG pathway analysis showed that proteins associated with energy intake,such as those involved in oxidation-reduction processes,glutathione metabolism,oxidoreductase activity,cofactor binding,catalytic activity and metabolic pathways,were significantly up-regulated in high-altitude populations;while proteins associated with energy expenditure,such as immune responses and processes,membrane attack complexes,natural killer pathway and other immune-related processes,were significantly down-regulated in expression.
基金supported by the National Natural Science Foundation of China (No. 31471988 and 31200287)
文摘Global climate change is a threat to animals in nearly all biomes and ecosystems, especially for ectotherm whose life activities highly depend on environmental thermal regime. Population genetic diversity which is essential for adaptation to environmental change is a useful index for long-term species survival. In this paper, genetic diversity of eight Phrynocephalus forsythii population which distributed in Tarim Basin, China, were evaluated based on three mtDNA gene and its correlation with environment factors were investigated using RDA. Our result revealed that, the level of genetic diversity of P. forsythii populations was related to its location but there was no significant correlation between genetic distances and geographic distances in P. forsythii. However, we find that mtDNA of P. forsythii was subjected to selection pressure during evolution and population genetic diversity was significantly positively related to variation coefficient of rainfall(VCR) and altitude(AL), while significantly negatively related to longitude(N) and annual average temperature(AAT). Our result supported the previous prediction that excessive ambient heat is a threat to P. forsythii.
基金supported by the National Natural Science Foundation of China (Nos. 21878222 and 21621004).
文摘In our previous work, a series of polyethylenimine(PEI)-derived cation exchangers were synthesized using PEIgrafted resin FF-PEI-L740(ionic capacity, 740 mmol·L^-1) as the basic resin to study lysozyme adsorption and chromatographic behavior. It was found that the resin with an ionic capacity of 630 mmol·L^-1(FF-PEI-CR630)possessed high adsorption performance towards lysozyme at 0–100 mmol·L^-1 Na Cl. Therefore, in this work,FF-PEI-CR630 was selected to study the influences of pH and ionic strength(IS) on protein adsorption and chromatographic behavior towards lysozyme. The increase of lysozyme adsorption capacity in the pH range of 6 to 10 was observed. However, the uptake rate decreased in the pH range of 6 to 8 and then remained essentially unchanged from pH 8 to pH 10. Increasing IS led to decreased protein adsorption capacity and increased uptake rate in different pH ranges. Besides, FF-PEI-CR630 maintained dynamic binding capacity as high as over150 mg·ml^-1 at pH 8–10 without NaCl. The research has thus provided insight into the selection of proper pH and IS conditions for protein purification by using FF-PEI-CR630.
基金supported by the National Natural Science Foundation of China (No.31471988 and No.31200287)。
文摘Speciation has never been directly observed in nature because it is a lengthy phenomenon.Although rare,ring species are an optimal natural example of speciation and can be identified through the assessment of the geographical conditions of their potential habitat.Phrynocephalus forsythii is endemic to the Tarim Basin,which compnses the Taklamakan Desert and surrounded by mountains on three sides.This study aimed to determine whether P.forsythii had a ring-species-like divergence pattern through the characterization of the genetic features of 17 populations covering the major distribution of this species.Species distribution modelling revealed that P.forsythii had a continuous circular distribution around the Tarim Basin.Gene flow was observed in most adjacent populations except for two terminal populations of the ring,which exhibit the highest differentiation.Genetic distance and geographic distance were significantly correlated,indicating that the observed differentiation resulted from genetic variation gradually accumulating during population dispersion.Although our results do not definitively indicate that P.forsythii is a ring species,our results indicate a ring-shaped diversification This phenomenon elucidates the potential mechanism underlying speciation in the presence of gene flow,providing insight into this evolutionary process.
基金supported by the National Natural Science Foundation of China (No.31471988 and N0.31200287)。
文摘The gut microbiota has gained attention because of its importance in facilitating host survival and evolution.However,it is unclear whether gut microbial communities are determined by the host(heritable factor) or environment(environmental factor).In this study,we investigated the gut microbial communities and potential functional signatures of two sympatric species distributed along an elevation gradient,the toadheaded lizards Phrynocephalus axillaris and P.forsythii.Our results indicated that at high elevations,the gut microbial communities of P.axillaris and P.forsythii did not significantly differ,and the phylogenetic relationships of gut microbial communities contradicted their hosts.At low altitudes,the two lizards could be distinguished based on their significantly different gut microbial communities.Compared to low-altitude populations,Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis showed that at higher altitudes,energy metabolism,such as carbohydrate,lipid,and amino acids metabolism were higher in both lizards.While a larger number of pathogenic bacteria were found in the lowaltitude population of P.forsythii.This suggests that the convergence of gut microbiota of two lizards at highaltitude stem from environmental factors,as they were exposed to the same environmental stress,whereas the divergence at low-altitude stemmed from heritable factors,as they were exposed to different environmental stresses.These results provide a new perspective regarding whether heritable or environmental factors dominate the gut microbiota during exposure to environmental stress.
文摘objective: to explore the effect of detail nursing intervention on headache and negative emotion in patients with subarachnoid hemorrhage. Methods: the clinical data of 100 cases of subarachnoid hemorrhage from January 2015 to January 2017 of neurosurgery in our hospital were randomly divided into the control group and the experimental group, Detail nursing intervention in experimental group, Comparison of two groups of clinical nursing effects. Results the duration of hospitalization and headache in the experimental group were shorter than those in the control group. Fewer headaches than control group (P<0.05) Less headache than control group (p<0.05). Results: the results of SAS and SDS scores were significantly lower than those in the control group (p<0.05) after nursing in the experimental group. Conclusion: the patients with subarachnoid hemorrhage receive detailed nursing intervention;contribute to the alleviation of their headache symptoms, Relieves the patient of negative emotional problems.
基金supported by the National Natural Science Foundation of China(No.52075407)Natural Science Foundation of Shaanxi Province of China(No.2019JM-034).
文摘The friction coefficient and wear rate of pretreated graphite with liquid nitrogen were obtained by using a ball-on-disk tester,and the wear of GCr15–graphite seal pairs with the low-temperature time-dependent pretreatment was discussed by comparing the wear morphology.The results show that liquid nitrogen pretreatment can affect the hardness and interlayer spacing of graphite.The range of the friction coefficients of pretreated graphite changes from 0.17 to 0.22.With the increase of liquid nitrogen pretreatment time,the wear mechanism of graphite would change from dominated three-body wear to adhesion wear.The experimental results of the mechanical seal with liquid nitrogen pretreatment show that the wear rate of stator is less than 0.00165 mm^(3)·N^(−1)·m^(−1),and the graphite shows a good low-temperature compatibility.
基金financially supported by National Natural Science Foundation of China (NSFC,Nos.81873921 and 51903174)Sino-German Cooperation Group Project (GZ1512)+2 种基金Chengdu Science and Technology Program (2020-GH02-00007-HZ,China)Sichuan University Postdoctoral Interdisciplinary Innovation Startup Foundationthe Fundamental Research Funds for Central Universities (2021SCU12070,China)
文摘Establishment of vaginal immune defenses at the mucosal interface layer through gene vaccines promise to prevent infectious diseases among females.Mucosal barriers composed of a flowing mucus hydrogel and tightly conjugated epithelial cells(ECs),which represent the main technical difficulties for vaccine development,reside in the harsh,acidic human vaginal environment.Different from frequently employed viral vectors,two types of nonviral nanocarriers were designed to concurrently overcome the barriers and induce immune responses.Differing design concepts include the charge-reversal property(DRLS)to mimic a virus that uses any cells as factories,as well as the addition of a hyaluronic acid coating(HA/RLS)to directly target dendritic cells(DCs).With a suitable size and electrostatic neutrality,these two nanoparticles penetrate a mucus hydrogel with similar diffusivity.The DRLS system expressed a higher level of the carried human papillomavirus type 16 L1 gene compared to HA/RLS in vivo.Therefore it induced more robust mucosal,cellular,and humoral immune responses.Moreover,the DLRS applied to intravaginal immunization induced high IgA levels compared with intramuscularly injected DNA(naked),indicating timely protection against pathogens at the mucus layer.These findings also offer important approaches for the design and fabrication of nonviral gene vaccines in other mucosal systems.
基金supported by the National Natural Science Foundation of China(Nos.61905005 and 52175375)the General Program of Science and Technology Development Project of Beijing Municipal Education Commission(No.KM202110005004)。
文摘The self-mixing interferometry(SMI)technique is an emerging sensing technology in microscale particle classification.However,due to the nature of the SMI effect raised by a microscattering particle,the signal analysis suffers from many problems compared with a macro target,such as lower signal-to-noise ratio(SNR),short transit time,and time-varying modulation strength.Therefore,the particle sizing measurement resolution is much lower than the one in typical displacement measurements.To solve these problems,in this paper,first,a theoretical model of the phase variation of a singleparticle SMI signal burst is demonstrated in detail.The relationship between the phase variation and the particle size is investigated,which predicts that phase observation could be another alternative for particle detection.Second,combined with continuous wavelet transform and Hilbert transform,a novel phase-unwrapping algorithm is proposed.This algorithm can implement not only efficient individual burst extraction from the noisy raw signal,but also precise phase calculation for particle sizing.The measurement shows good accuracy over a range from 100 nm to 6μm with our algorithm,proving that our algorithm enables a simple and reliable quantitative particle characteristics retrieval and analysis methodology for microscale particle detection in biomedical or laser manufacturing fields.
基金supported by the National Basic Research Program of China(973 Program)(No.2013CB02708201)
文摘In order to enhance the stability of single-phase microgrid,virtual synchronous generator(VSG)control method is investigated in this paper.Its electromagnetic model and electromechanical model are established to illustrate the performance of VSG.Considering the 2 nd fluctuation of fundamental-frequency in the output power,an instantaneous power calculation strategy is proposed based on the intrinsic frequency of single-phase VSG.Besides,a virtual power calculation method is presented to achieve islanded/grid-connected seamless transition.Stability analysis and comparison simulation results demonstrate the correctness of the presented power calculation method.At last,the effectiveness of the proposed approach is verified by comparison experiments of islanded/gridconnected operations in a 500 VA single-phase inverter.
基金The project was supported by the National Key Research Program-The Innovation of Eco-Modulator of Insect Ryanodine Re-ceptor(Nos.2018YFD0200100,2017YFD0200505)the National Natural Science Foundation of China(Nos.31972287,21602118).
文摘To search for potent insecticides targeting at ryanodine receptors(RyRs),a series of novel anthranilic diamides analogs containing 4-chlorine N-pyridylpyrazole were designed and synthesized.Their insecticidal activities were evaluated and the preliminary struc ture-activity relationships(SARs)were discussed.The insecticidal results showed that some of the compounds(8a-8h,8m,8n)exhibited good larvicidal activities against oriental armyworm at 2.5 mg·L^(-1),and compound 8m possessed 60%insecticidal activityat 0.5 mg·L^(-1).For diamondback moth,8m exhibited better activity than Chlorantraniliprole at a hundred fold preference.
基金This work was supported by the National Key R＆D Program of China （No. 2017YFA0205600）, and the National Natural Science Foundation of China （Nos. 51773191, 51573176 and 51633008）.
基金Supported by National Natural Science Foundation of China(51577010,51777012).
文摘The interaction between the source and load converters in cascaded DC-DC converters may cause instability.Thus,improving the stability of cascaded DC-DC converters is important.To solve the above-mentioned problem,a flowchart to improve the control method is established by calculating the eigenvalue sensitivity of a time-domain model of cascaded DC-DC converters.Further,an additional voltage-error mutual feedback control method is firstly proposed based on the flowchart provided in this study to improve the stability of cascaded DC-DC converters.Subsequently,the influence of the proposed mutual feedback control on the stability of cascaded DC-DC converters is analyzed.Finally,the effectiveness of the proposed control method is verified by simulation and experiment.
