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Screening of High Temperature Resistant Fodder Yeast Strains 被引量:1
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作者 Yufeng LIU Yueming WANG +3 位作者 Qingli YANG yanru ji Yan DONG jie SHI 《Agricultural Biotechnology》 CAS 2015年第4期58-60,69,共4页
[ Objective] This study aimed to screen yeast strains suitable for high temperature processing of formulated biological feed. [ Method ] High temperature resistance and culture conditions of six yeast strains were inv... [ Objective] This study aimed to screen yeast strains suitable for high temperature processing of formulated biological feed. [ Method ] High temperature resistance and culture conditions of six yeast strains were investigated. [Result] Two yeast strains resistant to high temperature (45 ℃ ) with high viable cell number (10^8 cells/ml) were screened, including DQFC2117-1 and DQFC2122-2. [ Conclusion] Strains DQFC2117-1 and DQFC2122-2 could be used as high temperature resistant yeast strains for processing of formulated biological feed. 展开更多
关键词 High temperature resistance Fodder yeast Formulated feed Biological feed
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Emerging Human Pluripotent Stem Cell-Based Human–Animal Brain Chimeras for Advancing Disease Modeling and Cell Therapy for Neurological Disorders
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作者 yanru ji Jenna Lillie McLean Ranjie Xu 《Neuroscience Bulletin》 SCIE CAS CSCD 2024年第9期1315-1332,共18页
Human pluripotent stem cell(hPSC)models provide unprecedented opportunities to study human neurological disorders by recapitulating human-specific disease mechanisms.In particular,hPSC-based human–animal brain chimer... Human pluripotent stem cell(hPSC)models provide unprecedented opportunities to study human neurological disorders by recapitulating human-specific disease mechanisms.In particular,hPSC-based human–animal brain chimeras enable the study of human cell pathophysiology in vivo.In chimeric brains,human neural and immune cells can maintain human-specific features,undergo maturation,and functionally integrate into host brains,allowing scientists to study how human cells impact neural circuits and animal behaviors.The emerging human–animal brain chimeras hold promise for modeling human brain cells and their interactions in health and disease,elucidating the disease mechanism from molecular and cellular to circuit and behavioral levels,and testing the efficacy of cell therapy interventions.Here,we discuss recent advances in the generation and applications of using human–animal chimeric brain models for the study of neurological disorders,including disease modeling and cell therapy. 展开更多
关键词 Human pluripotent stem cell Human–animal chimera Neurological disorder Disease modeling Cell therapy Human neurons and glia MICROGLIA Organoid
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Boron-promoted reductive deoxygenation coupling reaction of sulfonyl chlorides for the C(sp3)-S bond construction 被引量:1
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作者 Shuo Chen Qingru Wen +5 位作者 Yanqing Zhu yanru ji Yu Pu Zhengli Liu Yun He Zhang Feng 《Chinese Chemical Letters》 SCIE CAS CSCD 2022年第12期5101-5105,共5页
Herein,we report a borane-promoted reductive deoxygenation coupling reaction to synthesize sulfides.This reaction features excellent functional group compatibility,high efficiency,broad substrate scope,and application... Herein,we report a borane-promoted reductive deoxygenation coupling reaction to synthesize sulfides.This reaction features excellent functional group compatibility,high efficiency,broad substrate scope,and application in late-stage functionalization of biomolecules.Preliminary mechanistic studies suggest diaryl sulfides are the intermediates of this reaction.Moreover,the real active aryl sulfide anions may be generated in situ with the aid of B2pin2 and react with alkyl tosylates through a concerted SN2 pathway. 展开更多
关键词 C-S bond formation Reductive deoxygenation coupling BORANE Organosulfur compounds Green chemistry
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