Uroflowmetry is an uroflow measurement technique used to record the voided volume(VV)and flow rate,which can help clinicians objectively evaluate lower urinary tract function.Currently,few uroflowmetry studies have fo...Uroflowmetry is an uroflow measurement technique used to record the voided volume(VV)and flow rate,which can help clinicians objectively evaluate lower urinary tract function.Currently,few uroflowmetry studies have focused on the female population,[1]especially on the uroflow curve standard analysis.Hence,we sought to establish dependable uroflow reference values and nomograms for Chinese women and to evaluate the relationship between uroflow patterns and demographic data.展开更多
Metastatic pheochromocytoma/paraganglioma(MPP)is a rare endocrine tumor that originates from extra-adrenal chromaffin cells such as the paraganglia cells of sympathetic and parasympathetic nerves.It usually causes mul...Metastatic pheochromocytoma/paraganglioma(MPP)is a rare endocrine tumor that originates from extra-adrenal chromaffin cells such as the paraganglia cells of sympathetic and parasympathetic nerves.It usually causes multiple solid tumors and exhibits strong aggressiveness with poor prognosis,with a reported 5-year survival rate of less than 50%.Cases of brain and retroperitoneal metastases at the initial diagnosis have not yet been reported.We report a 41-year-old male patient initially diagnosed with MPP in the brain and retroperitoneum who underwent multi-disciplinary collaborative surgery and simultaneous removal of two tumors at our center.Postoperative pathology revealed infiltrative growth of a skull base tumor.The patient chose to receive the tyrosine kinase inhibitor sunitinib as a targeted treatment.A 3-month follow-up after surgery showed that the patient recovered well without signs of metastasis or recurrence.We present multi-disciplinary surgery under similar circumstances for enhanced treatment and postoperative management.The patient demonstrates a favorable prognosis during postoperative follow-up,indicating that simultaneous multidisciplinary surgery may offer greater benefits for MPP patients.展开更多
There are few experimental results available on film thickness at speeds above 5 m/s and they are almost all based on the optical ball-on-disc test rig.In contrast to the contacts in a rolling bearing,in which the lub...There are few experimental results available on film thickness at speeds above 5 m/s and they are almost all based on the optical ball-on-disc test rig.In contrast to the contacts in a rolling bearing,in which the lubricant in the oil reservoir distributes symmetrically,ball-on-disc contact shows asymmetry of lubricant distribution due to centrifugal effects.In order to closely imitate the contact occurring between the ball and the outer ring of a ball bearing,this study proposes an experimental model based on ball-on-glass ring contact.An optical matrix method is used to analyze the optical system,which is composed of a steel ball-lubricant-chromium-coated glass ring.Based on the optical analysis,the measurement system is improved in order to obtain a high quality interference image,which makes it possible to measure the film thickness at high-speeds conditions.展开更多
文摘Uroflowmetry is an uroflow measurement technique used to record the voided volume(VV)and flow rate,which can help clinicians objectively evaluate lower urinary tract function.Currently,few uroflowmetry studies have focused on the female population,[1]especially on the uroflow curve standard analysis.Hence,we sought to establish dependable uroflow reference values and nomograms for Chinese women and to evaluate the relationship between uroflow patterns and demographic data.
基金This study was supported by the National Key Research and Development Program of China(No.2018YFC2002202)the National High-Level Hospital Clinical Research Funding(No.BJ-2021-184).
文摘Metastatic pheochromocytoma/paraganglioma(MPP)is a rare endocrine tumor that originates from extra-adrenal chromaffin cells such as the paraganglia cells of sympathetic and parasympathetic nerves.It usually causes multiple solid tumors and exhibits strong aggressiveness with poor prognosis,with a reported 5-year survival rate of less than 50%.Cases of brain and retroperitoneal metastases at the initial diagnosis have not yet been reported.We report a 41-year-old male patient initially diagnosed with MPP in the brain and retroperitoneum who underwent multi-disciplinary collaborative surgery and simultaneous removal of two tumors at our center.Postoperative pathology revealed infiltrative growth of a skull base tumor.The patient chose to receive the tyrosine kinase inhibitor sunitinib as a targeted treatment.A 3-month follow-up after surgery showed that the patient recovered well without signs of metastasis or recurrence.We present multi-disciplinary surgery under similar circumstances for enhanced treatment and postoperative management.The patient demonstrates a favorable prognosis during postoperative follow-up,indicating that simultaneous multidisciplinary surgery may offer greater benefits for MPP patients.
基金The work was supported by the National Natural Science Foundation of China，the National Key Basic Research (973)Program of China
文摘There are few experimental results available on film thickness at speeds above 5 m/s and they are almost all based on the optical ball-on-disc test rig.In contrast to the contacts in a rolling bearing,in which the lubricant in the oil reservoir distributes symmetrically,ball-on-disc contact shows asymmetry of lubricant distribution due to centrifugal effects.In order to closely imitate the contact occurring between the ball and the outer ring of a ball bearing,this study proposes an experimental model based on ball-on-glass ring contact.An optical matrix method is used to analyze the optical system,which is composed of a steel ball-lubricant-chromium-coated glass ring.Based on the optical analysis,the measurement system is improved in order to obtain a high quality interference image,which makes it possible to measure the film thickness at high-speeds conditions.
