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BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition
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作者 Yu Meng Hui-Yan Sun +7 位作者 Yi He Qian Zhou yi-huang liu Hui Su Ming-Zhu Yin Fu-Rong Zeng Xiang Chen Guang-Tong Deng 《Military Medical Research》 SCIE CAS CSCD 2024年第4期620-624,共5页
Dear Editor,Ferroptosis,an iron-dependent form of cell death driven by overwhelming lipid peroxidation,represents a vulnerability in cancers,and therapeutic strategies to further potentiate ferroptosis hold great pote... Dear Editor,Ferroptosis,an iron-dependent form of cell death driven by overwhelming lipid peroxidation,represents a vulnerability in cancers,and therapeutic strategies to further potentiate ferroptosis hold great potential for melanoma treatment. 展开更多
关键词 MELANOMA Bromodomain and extra terminal domain(BET)inhibitor Ferroptosis Cell death AKR1C2 IMMUNOTHERAPY
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