Introduction Liver transplantation(LT)benefits patients with decompensated liver cirrhosis,acute liver failure,or hepatocellular carcinoma.The greatest challenge in LT is the insufficient number of donors for the grow...Introduction Liver transplantation(LT)benefits patients with decompensated liver cirrhosis,acute liver failure,or hepatocellular carcinoma.The greatest challenge in LT is the insufficient number of donors for the growing number of transplantation candidates.Various surgical strategies have been adopted to overcome the increasing donor-recipient disparity,including sequential/“domino”transplantation,split LT,use of marginal livers,and living donor LT(LDLT).To ensure the safety of donors and recipients,dual-graft LT may be considered(1).Herein,we describe the first successful hybrid-dual-graft LT in an obese patient requiring urgent LT,which involved transplantation of an otherwise-wasted resected liver lobe from a patient with a benign hepatic tumor and an inadequate-size living donor graft from the recipient’s father.展开更多
The COVID-19 pandemic remains complex,with concentrated and sporadic cases in multiple locations.During COVID-19 outbreaks,the routine diagnosis and treatment of liver cancer patients can be affected to a significant ...The COVID-19 pandemic remains complex,with concentrated and sporadic cases in multiple locations.During COVID-19 outbreaks,the routine diagnosis and treatment of liver cancer patients can be affected to a significant degree.For liver oncologists,it is important to identify strategies and protocols to reduce the risk of COVID-19 infection among patients and medical staff,use limited medical resources to maximally ensure access to anti-tumor treatment and related emergency treatment,and provide support for patients during the disruption caused by the pandemic.Given this requirement,eleven experts in liver cancer treatment-related disciplines from Zhongshan Hospital,Fudan University have written the Expert Guidance on the Overall Management of Liver Cancer During the COVID-19 Pandemic,which aims to provide a reference to assist liver oncologists in conducting clinical work safely and effectively while implementing COVID-19 prevention and control strategies and offer guidance on supporting liver cancer patients during the pandemic.展开更多
This paper reports a series of studies on the lubricant properties,elastohydrodynamic film thickness,and coefficients of friction of several commercially available ester base stocks,i.e.,diisooctyl phthalate(DIOP),dii...This paper reports a series of studies on the lubricant properties,elastohydrodynamic film thickness,and coefficients of friction of several commercially available ester base stocks,i.e.,diisooctyl phthalate(DIOP),diisodecyl phthalate(DIDP),diisotridecyl phthalate(DITDP),diisooctyl sebacate(DOS),diisotridecyl sebacate(DTDS),trihydroxymethylpropyl trioleate(TMPTO),and pentaerythritol tetraoleate(PETO).The results include densities and viscosities from 303 to 398 K,and elastohydrodynamic lubricant film thicknesses and friction in the boundary,mixed and full-film lubrication regimes measured at several temperatures,loads,and speeds.These ester base stocks have different lubrication abilities owing to their chain lengths,geometric configurations,and molecular rigidity.This study provides quantitative insight into the use of ester-based lubricants for low friction through the entire lubrication regime(boundary to full film)by utilization of suitable type and size of the ester base stocks.展开更多
基金supported by the National Natural Science Foundation of China(Nos.82150004,81830102),and Shanghai Municipal Key Clinical Specialty.
文摘Introduction Liver transplantation(LT)benefits patients with decompensated liver cirrhosis,acute liver failure,or hepatocellular carcinoma.The greatest challenge in LT is the insufficient number of donors for the growing number of transplantation candidates.Various surgical strategies have been adopted to overcome the increasing donor-recipient disparity,including sequential/“domino”transplantation,split LT,use of marginal livers,and living donor LT(LDLT).To ensure the safety of donors and recipients,dual-graft LT may be considered(1).Herein,we describe the first successful hybrid-dual-graft LT in an obese patient requiring urgent LT,which involved transplantation of an otherwise-wasted resected liver lobe from a patient with a benign hepatic tumor and an inadequate-size living donor graft from the recipient’s father.
文摘The COVID-19 pandemic remains complex,with concentrated and sporadic cases in multiple locations.During COVID-19 outbreaks,the routine diagnosis and treatment of liver cancer patients can be affected to a significant degree.For liver oncologists,it is important to identify strategies and protocols to reduce the risk of COVID-19 infection among patients and medical staff,use limited medical resources to maximally ensure access to anti-tumor treatment and related emergency treatment,and provide support for patients during the disruption caused by the pandemic.Given this requirement,eleven experts in liver cancer treatment-related disciplines from Zhongshan Hospital,Fudan University have written the Expert Guidance on the Overall Management of Liver Cancer During the COVID-19 Pandemic,which aims to provide a reference to assist liver oncologists in conducting clinical work safely and effectively while implementing COVID-19 prevention and control strategies and offer guidance on supporting liver cancer patients during the pandemic.
基金The Northwestern authors would also like to acknowledge the support from US Department of Energy(DE-EE0006449).
文摘This paper reports a series of studies on the lubricant properties,elastohydrodynamic film thickness,and coefficients of friction of several commercially available ester base stocks,i.e.,diisooctyl phthalate(DIOP),diisodecyl phthalate(DIDP),diisotridecyl phthalate(DITDP),diisooctyl sebacate(DOS),diisotridecyl sebacate(DTDS),trihydroxymethylpropyl trioleate(TMPTO),and pentaerythritol tetraoleate(PETO).The results include densities and viscosities from 303 to 398 K,and elastohydrodynamic lubricant film thicknesses and friction in the boundary,mixed and full-film lubrication regimes measured at several temperatures,loads,and speeds.These ester base stocks have different lubrication abilities owing to their chain lengths,geometric configurations,and molecular rigidity.This study provides quantitative insight into the use of ester-based lubricants for low friction through the entire lubrication regime(boundary to full film)by utilization of suitable type and size of the ester base stocks.