The South China Sea(SCS)is the largest marginal sea in the Northwest Pacific Ocean,and it encounters frequent typhoons.The atmosphere and ocean will create significant thermal and dynamic responses during the intense ...The South China Sea(SCS)is the largest marginal sea in the Northwest Pacific Ocean,and it encounters frequent typhoons.The atmosphere and ocean will create significant thermal and dynamic responses during the intense disturbance caused by typhoons.However,these responses have not been thoroughly investigated owing to the complicated marine environment.According to the satellite data,the SCS Basin was observed to have a strong sea surface temperature(SST)response to Typhoon Mangkhut,resulting in widespread SST cooling.A coupled model was used to investigate the atmospheric and oceanic responses to Typhoon Mangkhut.Best-track data,satellite SST,and ARGO measurements show that the coupled WRF-CROCO simulation displays better track,intensity,SST,temperature,and salinity profiles than those of the WRF-only simulation.Results show that the typhoon induced rightward intensifications in wind speed,ocean current,and SST.The following are some remarkable atmosphere and ocean responses:(1)the SST below the inner-core region is cooled by 1℃,resulting in a 37%-44%decrease in wet enthalpy,and the central pressure is increased by~9 hPa.Therefore,the changes in SST below the innercore region of the SCS Basin have a significant impact on air-sea fluxes under high-wind conditions;(2)the ocean boundary layer analysis shows that near-inertial oscillations on the right side of the typhoon track and a strong inertial current up to~2.28 m/s in the upper ocean were observed,which resonated with the local wind and flow field on the right side and induced strong SST cooling;(3)a decrease in SST decreased the moist static energy of the typhoon boundary layer,thereby weakening the typhoon’s intensity.The difference in equivalent potential temperature and sea surface pressure have a good correlation,indicating that the influence of moist static energy on typhoon intensity cannot be overlooked.展开更多
Oceanic front plays a significant role in the ocean vertical mixing and the regulation of air-sea interaction,among others.The western branch of the subarctic front(WSAF)located in the Northwest Pacific has attained l...Oceanic front plays a significant role in the ocean vertical mixing and the regulation of air-sea interaction,among others.The western branch of the subarctic front(WSAF)located in the Northwest Pacific has attained lots of attention given its strong intensity and widespread influence on this region.In this study,we take advantage of the merged sea surface temperature(SST)at a high spatial resolution of 0.05°to investigate the characteristics of WSAF.The front detection algorithm that combines the Sobel operator and histogram analysis is adopted.It is advantageous in both preserving the front intensity represented by the SST gradient as well as reducing the detection noise level.We systematically applied this algorithm to the daily SST products for front detection,based on which the WSAF characteristics including its intensity,occurrence of frequency,latitudinal position and coverage area are then extracted.WSAF is mostly located within a small latitude range between 40°N and 41°N with a clear seasonal trend in its intensity that peaks in the winter and troughs in the summer.The seasonal variation of WSAF intensity is almost consistent throughout the temporal period of interest from 2010 to 2018.Similar seasonality is observed for its occurrence of frequency with the winter-summer contrast reaching up to5%.The findings presented here shall help better interpret the WSAF characteristics in the long-term run as well as their impact on the regional weather and climate patterns at high spatial resolution.展开更多
The spatial distribution of eddy diffusivity,basic characteristics of coherent mesoscale eddies and their relationship are analyzed from numerical model outputs in the Southern Ocean.Mesoscale fluctuation information ...The spatial distribution of eddy diffusivity,basic characteristics of coherent mesoscale eddies and their relationship are analyzed from numerical model outputs in the Southern Ocean.Mesoscale fluctuation information is obtained by a temporal-spatial filtering method,and the eddy diffusivity is calculated using a linear regression analysis between isoneutral thickness flux and large-scale isoneutral thickness gradient.The eddy diffusivity is on the order of O(103 m2/s)with a significant spatial variation,and it is larger in the area with strong coherent mesoscale eddy activity.The mesoscale eddies are mainly located in the upper ocean layer,with the average intensity no larger than 0.2.The mean radius of the coherent mesoscale cyclonic(anticyclonic)eddy gradually decays from(121.2±10.4)km((117.8±9.6)km)at 30°S to(43.9±5.3)km((44.7±4.9)km)at 65°S.Their vertical penetration depths(lifespans)are deeper(longer)between the northern side of the Subpolar Antarctic Front and 48°S.The normalized eddy diffusivity and coherent mesoscale eddy activity show a significant positive correlation,indicating that coherent mesoscale eddy plays an important role in eddy diffusivity.展开更多
The present climate simulation and future projection of the mixed layer depth(MLD)and subduction process in the subtropical Southeast Pacific are investigated based on the geophysical fluid dynamics laboratory earth s...The present climate simulation and future projection of the mixed layer depth(MLD)and subduction process in the subtropical Southeast Pacific are investigated based on the geophysical fluid dynamics laboratory earth system model(GFDL-ESM2 M).The MLD deepens from May and reaches its maximum(>160 m)near(24°S,104°W)in September in the historical simulation.The MLD spatial pattern in September is non-uniform in the present climate,which shows three characteristics:(1)the deep MLD extends from the Southeast Pacific to the West Pacific and leads to a"deep tongue"until 135°W;(2)the northern boundary of the MLD maximum is smoothly near 18°S,and MLD shallows sharply to the northeast;(3)there is a relatively shallow MLD zone inserted into the MLD maximum eastern boundary near(26°S,80°W)as a weak"shallow tongue".The MLD nonuniform spatial pattern generates three strong MLD fronts respectively in the three key regions,promoting the subduction rate.After global warming,the variability of MLD spatial patterns is remarkably diverse,rather than deepening consistently.In all the key regions,the MLD deepens in the south but shoals in the north,strengthing the MLD front.As a result,the subduction rate enhances in these areas.This MLD antisymmetric variability is mainly influenced by various factors,especially the potential-density horizontal advection non-uniform changes.Notice that the freshwater flux change helps to deepen the MLD uniformly in the whole basin,so it hardly works on the regional MLD variability.The study highlights that there are regional differences in the mechanisms of the MLD change,and the MLD front change caused by MLD non-uniform variability is the crucial factor in the subduction response to global warming.展开更多
We investigated the interaction between mesoscale eddies and the Kuroshio Current east of Taiwan,China,using a fine-resolution regional general circulation model.Mesoscale eddies are injected into a region east of Tai...We investigated the interaction between mesoscale eddies and the Kuroshio Current east of Taiwan,China,using a fine-resolution regional general circulation model.Mesoscale eddies are injected into a region east of Taiwan,China,according to the quasi-geostrophic theory of stratified fluids.Modeled eddies propagated westward at the velocity of the first baroclinic mode Rossby wave.When eddies collide with the Kuroshio Current east of Taiwan,China,the spatial structure and volume transport of the Kuroshio Current shows a significant variation.The upper 600 m of the anticyclonic eddy cannot cross the Kuroshio Current to reach the region west of the Kuroshio Current;rather,these waters flow northward along the eastern side of the Kuroshio Current.The upper water carried by the anticyclonic eddies cannot reach the shelf of the East China Sea(ECS).In contrast,the waters in the upper layer of the cyclonic eddy reach the western side of the Kuroshio Current and then flow northward.The dynamic mechanism analysis shows that the interaction between the Kuroshio Current and the cyclonic(anticyclonic)eddy decrease(increase)the horizontal potential vorticity(PV)gradient,or PV barrier,whereby the cyclonic(anticyclonic)eddy can(cannot)cross the Kuroshio Current.This study implies that the continental shelf could potentially be influenced by cyclonic eddies in the open ocean,which can transport heat and material from the upper open ocean across the Kuroshio Current to the shelf waters.展开更多
The internal energy distribution of waves can be described using ocean-wave spectra.In many ways,obtaining wave spectra on a global scale is critical.Surface waves investigation and monitoring onboard the Chinese-Fren...The internal energy distribution of waves can be described using ocean-wave spectra.In many ways,obtaining wave spectra on a global scale is critical.Surface waves investigation and monitoring onboard the Chinese-French oceanography satellite is the first space-borne instrument for detecting wave spectra specially,which was launched on October 29,2018.It can avoid the shortage of synthetic aperture radar detection results while still having some problems,especially with the effects of speckle noise.In this study,a method to suppress the speckle noise is proposed.First,the empirical formula for background speckle noise is established.Second,many spatio-temporal representative fluctuation spectra are classified and averaged.Third,rational transfer function filtering is used to obtain speckle noise close to the along-track direction.Finally,a signal-to-noise ratio threshold is used to suppress the abnormal speckle noise.This method solves the problems existing in previous denoising methods,such as excessive denoising in the along-track direction and the inability of some abnormal noises to be denoised in the two-dimensional directional wave spectra.展开更多
A microbial fuel cell(MFC)is a novel promising technology for simultaneous renewable electricity generation and wastewater treatment.Three non-comparable objectives,i.e.power density,attainable current density and was...A microbial fuel cell(MFC)is a novel promising technology for simultaneous renewable electricity generation and wastewater treatment.Three non-comparable objectives,i.e.power density,attainable current density and waste removal ratio,are often conflicting.A thorough understanding of the relationship among these three conflicting objectives can be greatly helpful to assist in optimal operation of MFC system.In this study,a multiobjective genetic algorithm is used to simultaneously maximizing power density,attainable current density and waste removal ratio based on a mathematical model for an acetate two-chamber MFC.Moreover,the level diagrams method is utilized to aid in graphical visualization of Pareto front and decision making.Three biobjective optimization problems and one three-objective optimization problem are thoroughly investigated.The obtained Pareto fronts illustrate the complex relationships among these three objectives,which is helpful for final decision support.Therefore,the integrated methodology of a multi-objective genetic algorithm and a graphical visualization technique provides a promising tool for the optimal operation of MFCs by simultaneously considering multiple conflicting objectives.展开更多
We aim to directly invert wave parameters by using the data of a compact polarimetric synthetic aperture radar(CP SAR)and validate the effectiveness of ocean wave parameter retrieval from the circular transmit/linear ...We aim to directly invert wave parameters by using the data of a compact polarimetric synthetic aperture radar(CP SAR)and validate the effectiveness of ocean wave parameter retrieval from the circular transmit/linear receive mode andπ/4 compact polarimetric mode.Relevant data from the RADARSAT-2 fully polarimetric SAR on the C-band were used to obtain the compact polarimetric SAR images,and a polarimetric SAR wave retrieval algorithm was used to verify the sea surface wave measurements.Using the data and algorithm,there is no need to estimate complex hydrodynamic modulation transfer functions,even at large radar incidence angles.First,the radar backscattering cross-sections and backscattering cross-section of the radar linearly polarized with any polarization orientation angle were calculated in the two compact polarimetric SAR modes.Then,the wave slopes along the azimuth direction and the range direction were calculated directly using CP SAR data.Finally,we obtained the slope spectrum of the wave from the estimated wave slopes along azimuth and range directions.The wave parameters extracted from the synthetic wave slope spectrum were compared with those obtained from buoy observations of the National Data Buoy Center,verifying a suitable agreement.展开更多
The velocity and direction of internal waves(IWs) are important parameters of the ocean,however,traditional observation methods can only obtain the average parameters of IWs for a single location or large area.Herein,...The velocity and direction of internal waves(IWs) are important parameters of the ocean,however,traditional observation methods can only obtain the average parameters of IWs for a single location or large area.Herein,a new method based on optical flow is proposed to derive the phase velocity vectors of IWs from X-band marine radar images.First,the X-band marine radar image sequence is averaged,and ramp correction is used to reduce the attenuation of gray values with increasing radial range.Second,the average propagation direction of the IWs is determined using the two-dimensional Fourier transform of the radar images;two radial profiles along this direction are selected from two adjacent radar images;and then,the average phase velocity of the IWs is estimated from these radial profiles.Third,the averaged radar images are processed via histogram equalization and binarization to reduce the influence of noise on the radar images.Fourth,a weighting factor is determined using the average phase velocity of a reference point;the phase velocities on the wave crest of the IWs are subsequently estimated via the optical flow method.Finally,the proposed method is validated using X-band marine radar image sequences observed on an oil platform in the South China Sea,and the error of the phase velocity is calculated to be 0.000 3–0.073 8 m/s.The application conditions of the proposed method are also discussed using two different types of IW packets.展开更多
This paper proposes a multifunction radar that can not only measure sea currents but also perform sea-surface imaging.The fundamental aspect of the proposed radar comprises transmitting time-shifted up-and-down contin...This paper proposes a multifunction radar that can not only measure sea currents but also perform sea-surface imaging.The fundamental aspect of the proposed radar comprises transmitting time-shifted up-and-down continuous wave linear frequency modulated signals that allow for the offset of two one-dimensional range images of the sea surface that respectively correspond to the upward linear frequency modulated(LFM)signal and the downward LFM signal.Owing to the Doppler frequency shift from the sea surface,a range offset,which is proportional to the radial velocity of the sea surface,occurs between the upward and downward LFM signals.By using the least-squares linear fitting method in the transformed domain,the range offset can be measured and the current velocity can be retrieved.Finally,we verify the accuracy of current measurement with simulation results.展开更多
Successful wound healing depends on the reconstruction of proper tissue homeostasis,particularly in the posttraumatic inflammatory tissue microenvironment.Diabetes jeopardizes tissues’immune homeostasis in cutaneous ...Successful wound healing depends on the reconstruction of proper tissue homeostasis,particularly in the posttraumatic inflammatory tissue microenvironment.Diabetes jeopardizes tissues’immune homeostasis in cutaneous wounds,causing persistent chronic inflammation and cytokine dysfunction.Previously,we developed an autologous regeneration factor(ARF)technology to extract the cytokine composite from autologous tissue to restore immune homeostasis and promote wound healing.However,treatment efficacy was significantly compromised in diabetic conditions.Therefore,we proposed that a combination of melatonin and ARF,which is beneficial for proper immune homeostasis reconstruction,could be an effective treatment for diabetic wounds.Our research showed that the utilization of melatonin-mediated ARF biogel(AM gel)promoted diabetic wound regeneration at a more rapid healing rate.RNA-Seq analysis showed that AM gel treatment could restore more favorable immune tissue homeostasis with unique inflammatory patterning as a result of the diminished intensity of acute and chronic inflammation.Currently,AM gel could be a novel and promising therapeutic strategy for diabetic wounds in clinical practice through favorable immune homeostatic reconstructions in the tissue microenvironment and proper posttraumatic inflammation patterning.展开更多
The risk of emerging infectious diseases(EID)is increasing globally.More than 60%of EIDs worldwide are caused by animal-borne pathogens.This study aimed to characterize the virome,analyze the phylogenetic evolution,an...The risk of emerging infectious diseases(EID)is increasing globally.More than 60%of EIDs worldwide are caused by animal-borne pathogens.This study aimed to characterize the virome,analyze the phylogenetic evolution,and determine the diversity of rodent-borne viruses in Hainan Province,China.We collected 682 anal and throat samples from rodents,combined them into 28 pools according to their species and location,and processed them for next-generation sequencing and bioinformatics analysis.The diverse viral contigs closely related to mammals were assigned to 22 viral families.Molecular clues of the important rodent-borne viruses were further identified by polymerase chain reaction for phylogenetic analysis and annotation of genetic characteristics such as arenavirus,coronavirus,astrovirus,pestivirus,parvovirus,and papillomavirus.We identified pestivirus and bocavirus in Leopoldoms edwardsi from Huangjinjiaoling,and bocavirus in Rattus andamanensis from the national nature reserves of Bangxi with low amino acid identity to known pathogens are proposed as the novel species,and their rodent hosts have not been previously reported to carry these viruses.These results expand our knowledge of viral classification and host range and suggest that there are highly diverse,undiscovered viruses that have evolved independently in their unique wildlife hosts in inaccessible areas.展开更多
The authors regret a mistake of funding numbers in the Acknowledgment Section failed to be corrected during proofreading.Below is the corrected funding statement in ACKNOWLEDGMENT SECTION:This work was supported by th...The authors regret a mistake of funding numbers in the Acknowledgment Section failed to be corrected during proofreading.Below is the corrected funding statement in ACKNOWLEDGMENT SECTION:This work was supported by the National Natural Science Foundation of China(NSFC)(Nos.82072415,81772354,81902189),Clinical Innovation Research Program of Guangzhou Regenerative Medicine and Health Guangdong Laboratory(2018GZR0201002),Science Technology Project of Guangzhou City(2019ZD15).展开更多
The potential translation of bio-inert polymer scaffolds as bone substitutes is limited by the lack of neovascularization upon implantation and subsequently diminished ingrowth of host bone,most likely resulted from t...The potential translation of bio-inert polymer scaffolds as bone substitutes is limited by the lack of neovascularization upon implantation and subsequently diminished ingrowth of host bone,most likely resulted from the inability to replicate appropriate endogenous crosstalk between cells.Human umbilical vein endothelial cell-derived decellularized extracellular matrix(HdECM),which contains a collection of angiocrine biomolecules,has recently been demonstrated to mediate endothelial cells(ECs)-osteoprogenitors(OPs)crosstalk.We employed the HdECM to create a PCL(polycaprolactone)/fibrin/HdECM(PFE)hybrid scaffold.We hypothesized PFE scaffold could reconstitute a bio-instructive microenvironment that reintroduces the crosstalk,resulting in vascularized bone regeneration.Following implantation in a rat femoral bone defect,the PFE scaffold demonstrated early vascular infiltration and enhanced bone regeneration by microangiography(μ-AG)and micro-computational tomography(μ-CT).Based on the immunofluorescence studies,PFE mediated the endogenous angiogenesis and osteogenesis with a substantial number of type H vessels and osteoprogenitors.In addition,superior osseointegration was observed by a direct host bone-PCL interface,which was likely attributed to the formation of type H vessels.The bio-instructive microenvironment created by our innovative PFE scaffold made possible superior osseointegration and type H vessel-related bone regeneration.It could become an alternative solution of improving the osseointegration of bone substitutes with the help of induced type H vessels,which could compensate for the inherent biological inertness of synthetic polymers.展开更多
基金Supported by the National Natural Science Foundation of China (No. 41620104003)the Postgraduate Research and Practice Innovation Program of Jiangsu Province (Nos. SJKY19_0951, KYCX21_0959)
文摘The South China Sea(SCS)is the largest marginal sea in the Northwest Pacific Ocean,and it encounters frequent typhoons.The atmosphere and ocean will create significant thermal and dynamic responses during the intense disturbance caused by typhoons.However,these responses have not been thoroughly investigated owing to the complicated marine environment.According to the satellite data,the SCS Basin was observed to have a strong sea surface temperature(SST)response to Typhoon Mangkhut,resulting in widespread SST cooling.A coupled model was used to investigate the atmospheric and oceanic responses to Typhoon Mangkhut.Best-track data,satellite SST,and ARGO measurements show that the coupled WRF-CROCO simulation displays better track,intensity,SST,temperature,and salinity profiles than those of the WRF-only simulation.Results show that the typhoon induced rightward intensifications in wind speed,ocean current,and SST.The following are some remarkable atmosphere and ocean responses:(1)the SST below the inner-core region is cooled by 1℃,resulting in a 37%-44%decrease in wet enthalpy,and the central pressure is increased by~9 hPa.Therefore,the changes in SST below the innercore region of the SCS Basin have a significant impact on air-sea fluxes under high-wind conditions;(2)the ocean boundary layer analysis shows that near-inertial oscillations on the right side of the typhoon track and a strong inertial current up to~2.28 m/s in the upper ocean were observed,which resonated with the local wind and flow field on the right side and induced strong SST cooling;(3)a decrease in SST decreased the moist static energy of the typhoon boundary layer,thereby weakening the typhoon’s intensity.The difference in equivalent potential temperature and sea surface pressure have a good correlation,indicating that the influence of moist static energy on typhoon intensity cannot be overlooked.
基金The Natural Science Foundation of Jiangsu Province under contract No.BK20210666the National Natural Science Foundation of China under contract Nos 41620104003 and 42006163+2 种基金the Startup Foundation for Introducing Talent of Nanjing University of Information Science&Technologythe National Key Research and Development Program of China under contract No.2021YFB3901004the Graduate Innovation Project of Jiangsu Province under contract No.KYCX21_0980。
文摘Oceanic front plays a significant role in the ocean vertical mixing and the regulation of air-sea interaction,among others.The western branch of the subarctic front(WSAF)located in the Northwest Pacific has attained lots of attention given its strong intensity and widespread influence on this region.In this study,we take advantage of the merged sea surface temperature(SST)at a high spatial resolution of 0.05°to investigate the characteristics of WSAF.The front detection algorithm that combines the Sobel operator and histogram analysis is adopted.It is advantageous in both preserving the front intensity represented by the SST gradient as well as reducing the detection noise level.We systematically applied this algorithm to the daily SST products for front detection,based on which the WSAF characteristics including its intensity,occurrence of frequency,latitudinal position and coverage area are then extracted.WSAF is mostly located within a small latitude range between 40°N and 41°N with a clear seasonal trend in its intensity that peaks in the winter and troughs in the summer.The seasonal variation of WSAF intensity is almost consistent throughout the temporal period of interest from 2010 to 2018.Similar seasonality is observed for its occurrence of frequency with the winter-summer contrast reaching up to5%.The findings presented here shall help better interpret the WSAF characteristics in the long-term run as well as their impact on the regional weather and climate patterns at high spatial resolution.
基金The National Key Research Programs of China under contract No.2017YFA0604100the National Natural Science Foundation of China under contract Nos 41906008,41806039 and 41706205+3 种基金the Open Fund of State Key Laboratory of Satellite Ocean Environment Dynamics,Second Institute of Oceanography,MNR under contract No.QNHX2022the Startup Foundation for Introducing Talent of Nanjing University of Information Science&Technology under contract No.2019r049the Startup Foundation for Introducing Talent of Zhejiang Ocean Universitythe Innovation Group Project of Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)under contract No.311020004。
文摘The spatial distribution of eddy diffusivity,basic characteristics of coherent mesoscale eddies and their relationship are analyzed from numerical model outputs in the Southern Ocean.Mesoscale fluctuation information is obtained by a temporal-spatial filtering method,and the eddy diffusivity is calculated using a linear regression analysis between isoneutral thickness flux and large-scale isoneutral thickness gradient.The eddy diffusivity is on the order of O(103 m2/s)with a significant spatial variation,and it is larger in the area with strong coherent mesoscale eddy activity.The mesoscale eddies are mainly located in the upper ocean layer,with the average intensity no larger than 0.2.The mean radius of the coherent mesoscale cyclonic(anticyclonic)eddy gradually decays from(121.2±10.4)km((117.8±9.6)km)at 30°S to(43.9±5.3)km((44.7±4.9)km)at 65°S.Their vertical penetration depths(lifespans)are deeper(longer)between the northern side of the Subpolar Antarctic Front and 48°S.The normalized eddy diffusivity and coherent mesoscale eddy activity show a significant positive correlation,indicating that coherent mesoscale eddy plays an important role in eddy diffusivity.
基金The National Natural Science Foundation of China under contract Nos 41606217 and 41620104003the Open Fund of Key Laboratory for Polar Science,Polar Research Institute of China,Ministry of Natural Resources,under contract No.KP201702the Open Fund of the Key Laboratory of Ocean Circulation and Waves,Chinese Academy of Sciences,under contract No.KLOCW1903
文摘The present climate simulation and future projection of the mixed layer depth(MLD)and subduction process in the subtropical Southeast Pacific are investigated based on the geophysical fluid dynamics laboratory earth system model(GFDL-ESM2 M).The MLD deepens from May and reaches its maximum(>160 m)near(24°S,104°W)in September in the historical simulation.The MLD spatial pattern in September is non-uniform in the present climate,which shows three characteristics:(1)the deep MLD extends from the Southeast Pacific to the West Pacific and leads to a"deep tongue"until 135°W;(2)the northern boundary of the MLD maximum is smoothly near 18°S,and MLD shallows sharply to the northeast;(3)there is a relatively shallow MLD zone inserted into the MLD maximum eastern boundary near(26°S,80°W)as a weak"shallow tongue".The MLD nonuniform spatial pattern generates three strong MLD fronts respectively in the three key regions,promoting the subduction rate.After global warming,the variability of MLD spatial patterns is remarkably diverse,rather than deepening consistently.In all the key regions,the MLD deepens in the south but shoals in the north,strengthing the MLD front.As a result,the subduction rate enhances in these areas.This MLD antisymmetric variability is mainly influenced by various factors,especially the potential-density horizontal advection non-uniform changes.Notice that the freshwater flux change helps to deepen the MLD uniformly in the whole basin,so it hardly works on the regional MLD variability.The study highlights that there are regional differences in the mechanisms of the MLD change,and the MLD front change caused by MLD non-uniform variability is the crucial factor in the subduction response to global warming.
基金Supported by the National Key Research Development Program of China(No.2017YFC1404000)the Open Fund of the Key Laboratory of Ocean Circulation and Waves,Chinese Academy of Sciences(No.KLOCW1802)+2 种基金the Startup Foundation for Introducing Talent of NUIST(No.2017r092)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB42000000)the National Natural Science Foundation of China(No.41876019)。
文摘We investigated the interaction between mesoscale eddies and the Kuroshio Current east of Taiwan,China,using a fine-resolution regional general circulation model.Mesoscale eddies are injected into a region east of Taiwan,China,according to the quasi-geostrophic theory of stratified fluids.Modeled eddies propagated westward at the velocity of the first baroclinic mode Rossby wave.When eddies collide with the Kuroshio Current east of Taiwan,China,the spatial structure and volume transport of the Kuroshio Current shows a significant variation.The upper 600 m of the anticyclonic eddy cannot cross the Kuroshio Current to reach the region west of the Kuroshio Current;rather,these waters flow northward along the eastern side of the Kuroshio Current.The upper water carried by the anticyclonic eddies cannot reach the shelf of the East China Sea(ECS).In contrast,the waters in the upper layer of the cyclonic eddy reach the western side of the Kuroshio Current and then flow northward.The dynamic mechanism analysis shows that the interaction between the Kuroshio Current and the cyclonic(anticyclonic)eddy decrease(increase)the horizontal potential vorticity(PV)gradient,or PV barrier,whereby the cyclonic(anticyclonic)eddy can(cannot)cross the Kuroshio Current.This study implies that the continental shelf could potentially be influenced by cyclonic eddies in the open ocean,which can transport heat and material from the upper open ocean across the Kuroshio Current to the shelf waters.
文摘The internal energy distribution of waves can be described using ocean-wave spectra.In many ways,obtaining wave spectra on a global scale is critical.Surface waves investigation and monitoring onboard the Chinese-French oceanography satellite is the first space-borne instrument for detecting wave spectra specially,which was launched on October 29,2018.It can avoid the shortage of synthetic aperture radar detection results while still having some problems,especially with the effects of speckle noise.In this study,a method to suppress the speckle noise is proposed.First,the empirical formula for background speckle noise is established.Second,many spatio-temporal representative fluctuation spectra are classified and averaged.Third,rational transfer function filtering is used to obtain speckle noise close to the along-track direction.Finally,a signal-to-noise ratio threshold is used to suppress the abnormal speckle noise.This method solves the problems existing in previous denoising methods,such as excessive denoising in the along-track direction and the inability of some abnormal noises to be denoised in the two-dimensional directional wave spectra.
基金Supported by the National Natural Science Foundation of China(21576163)the Major State Basic Research Development Program of China(2014CB239703)+1 种基金the Science and Technology Commission of Shanghai Municipality(14DZ2250800)the Project-sponsored by SRF for ROCS,SEM
文摘A microbial fuel cell(MFC)is a novel promising technology for simultaneous renewable electricity generation and wastewater treatment.Three non-comparable objectives,i.e.power density,attainable current density and waste removal ratio,are often conflicting.A thorough understanding of the relationship among these three conflicting objectives can be greatly helpful to assist in optimal operation of MFC system.In this study,a multiobjective genetic algorithm is used to simultaneously maximizing power density,attainable current density and waste removal ratio based on a mathematical model for an acetate two-chamber MFC.Moreover,the level diagrams method is utilized to aid in graphical visualization of Pareto front and decision making.Three biobjective optimization problems and one three-objective optimization problem are thoroughly investigated.The obtained Pareto fronts illustrate the complex relationships among these three objectives,which is helpful for final decision support.Therefore,the integrated methodology of a multi-objective genetic algorithm and a graphical visualization technique provides a promising tool for the optimal operation of MFCs by simultaneously considering multiple conflicting objectives.
基金The National Natural Science Foundation of China under contract Nos 41620104003 and 42027805the National Key Research and Development Program under contract No.2016YFC1401002。
文摘We aim to directly invert wave parameters by using the data of a compact polarimetric synthetic aperture radar(CP SAR)and validate the effectiveness of ocean wave parameter retrieval from the circular transmit/linear receive mode andπ/4 compact polarimetric mode.Relevant data from the RADARSAT-2 fully polarimetric SAR on the C-band were used to obtain the compact polarimetric SAR images,and a polarimetric SAR wave retrieval algorithm was used to verify the sea surface wave measurements.Using the data and algorithm,there is no need to estimate complex hydrodynamic modulation transfer functions,even at large radar incidence angles.First,the radar backscattering cross-sections and backscattering cross-section of the radar linearly polarized with any polarization orientation angle were calculated in the two compact polarimetric SAR modes.Then,the wave slopes along the azimuth direction and the range direction were calculated directly using CP SAR data.Finally,we obtained the slope spectrum of the wave from the estimated wave slopes along azimuth and range directions.The wave parameters extracted from the synthetic wave slope spectrum were compared with those obtained from buoy observations of the National Data Buoy Center,verifying a suitable agreement.
基金The National Natural Science Foundation of China under contract Nos 41620104003 and 42027805the National Natural Science Youth Foundation of China under contract No.41506199。
文摘The velocity and direction of internal waves(IWs) are important parameters of the ocean,however,traditional observation methods can only obtain the average parameters of IWs for a single location or large area.Herein,a new method based on optical flow is proposed to derive the phase velocity vectors of IWs from X-band marine radar images.First,the X-band marine radar image sequence is averaged,and ramp correction is used to reduce the attenuation of gray values with increasing radial range.Second,the average propagation direction of the IWs is determined using the two-dimensional Fourier transform of the radar images;two radial profiles along this direction are selected from two adjacent radar images;and then,the average phase velocity of the IWs is estimated from these radial profiles.Third,the averaged radar images are processed via histogram equalization and binarization to reduce the influence of noise on the radar images.Fourth,a weighting factor is determined using the average phase velocity of a reference point;the phase velocities on the wave crest of the IWs are subsequently estimated via the optical flow method.Finally,the proposed method is validated using X-band marine radar image sequences observed on an oil platform in the South China Sea,and the error of the phase velocity is calculated to be 0.000 3–0.073 8 m/s.The application conditions of the proposed method are also discussed using two different types of IW packets.
基金The National Key Research and Development Program under contract No.2016YFC1401002the National Natural Science Foundation of China under contract Nos 41606201,41576173,41620104003 and 41706202.
文摘This paper proposes a multifunction radar that can not only measure sea currents but also perform sea-surface imaging.The fundamental aspect of the proposed radar comprises transmitting time-shifted up-and-down continuous wave linear frequency modulated signals that allow for the offset of two one-dimensional range images of the sea surface that respectively correspond to the upward linear frequency modulated(LFM)signal and the downward LFM signal.Owing to the Doppler frequency shift from the sea surface,a range offset,which is proportional to the radial velocity of the sea surface,occurs between the upward and downward LFM signals.By using the least-squares linear fitting method in the transformed domain,the range offset can be measured and the current velocity can be retrieved.Finally,we verify the accuracy of current measurement with simulation results.
基金supported by the National Natural Science Foundation of China(NSFC)(Nos.81772354,81902189,82072409)Clinical Innovation Research Program of Guangzhou Regenerative Medicine and Health Guangdong Laboratory(2018GZR0201002)+3 种基金Science Technology Project of Guangzhou City(201804010185)Natural Science Foundation of Guangdong Province(2019A1515012020)Science and Technology Innovation Project of Foshan City(1920001000025)National Young Thousand-Talent Scheme to Zhang Zhi-Yong.
文摘Successful wound healing depends on the reconstruction of proper tissue homeostasis,particularly in the posttraumatic inflammatory tissue microenvironment.Diabetes jeopardizes tissues’immune homeostasis in cutaneous wounds,causing persistent chronic inflammation and cytokine dysfunction.Previously,we developed an autologous regeneration factor(ARF)technology to extract the cytokine composite from autologous tissue to restore immune homeostasis and promote wound healing.However,treatment efficacy was significantly compromised in diabetic conditions.Therefore,we proposed that a combination of melatonin and ARF,which is beneficial for proper immune homeostasis reconstruction,could be an effective treatment for diabetic wounds.Our research showed that the utilization of melatonin-mediated ARF biogel(AM gel)promoted diabetic wound regeneration at a more rapid healing rate.RNA-Seq analysis showed that AM gel treatment could restore more favorable immune tissue homeostasis with unique inflammatory patterning as a result of the diminished intensity of acute and chronic inflammation.Currently,AM gel could be a novel and promising therapeutic strategy for diabetic wounds in clinical practice through favorable immune homeostatic reconstructions in the tissue microenvironment and proper posttraumatic inflammation patterning.
基金This work was supported by Key Research and Development Plan of Hainan Province(No.ZDYF2020150,and ZDYF2022SHFZ085)the National Natural Science Foundation of China(Nos.32060015,81860367 and 82060378)+7 种基金CAMS Innovation Fund for Medical Sciences(CIFMS)(grant 2021-I2M-1-037,Grant No.2021-I2M-1-039)the Major Science and Technology Program of Hainan Province(No.ZDKJ202003)the Hainan Provincial Natural Science Foundation of China(Nos.820RC628 and 2019RC218)the National Key R&D Program of China(Grant No.2022YFE0210300)the Scientific Research Foundation of the Higher Education Institutions of Hainan Province,China(No.Hnky2021-40)the Research Project of the Hainan Academician Innovation Platform(No.YSPTZX202004)the Hainan Talent Development Project(No.SRC200003)Graduate student innovation grant of Hainan Medical University(No.HYYS2020-33,Hys2020-360,Hys2020-376 and Qhys2021-356)。
文摘The risk of emerging infectious diseases(EID)is increasing globally.More than 60%of EIDs worldwide are caused by animal-borne pathogens.This study aimed to characterize the virome,analyze the phylogenetic evolution,and determine the diversity of rodent-borne viruses in Hainan Province,China.We collected 682 anal and throat samples from rodents,combined them into 28 pools according to their species and location,and processed them for next-generation sequencing and bioinformatics analysis.The diverse viral contigs closely related to mammals were assigned to 22 viral families.Molecular clues of the important rodent-borne viruses were further identified by polymerase chain reaction for phylogenetic analysis and annotation of genetic characteristics such as arenavirus,coronavirus,astrovirus,pestivirus,parvovirus,and papillomavirus.We identified pestivirus and bocavirus in Leopoldoms edwardsi from Huangjinjiaoling,and bocavirus in Rattus andamanensis from the national nature reserves of Bangxi with low amino acid identity to known pathogens are proposed as the novel species,and their rodent hosts have not been previously reported to carry these viruses.These results expand our knowledge of viral classification and host range and suggest that there are highly diverse,undiscovered viruses that have evolved independently in their unique wildlife hosts in inaccessible areas.
文摘The authors regret a mistake of funding numbers in the Acknowledgment Section failed to be corrected during proofreading.Below is the corrected funding statement in ACKNOWLEDGMENT SECTION:This work was supported by the National Natural Science Foundation of China(NSFC)(Nos.82072415,81772354,81902189),Clinical Innovation Research Program of Guangzhou Regenerative Medicine and Health Guangdong Laboratory(2018GZR0201002),Science Technology Project of Guangzhou City(2019ZD15).
基金This work was supported by the National Natural Science Foundation of China(NSFC)(Nos.82072415,81772354,81902189)Clinical Innovation Research Program of Guangzhou Regenerative Medicine and Health Guangdong Laboratory(2018GZR0201001)+3 种基金Science Technology Project of Guangzhou City(2019ZD15)Collegiate Innovation and Entrepreneurship Education Project of Guangzhou City(2019PT104)Science and Technology Innovation Project of Foshan City(1920001000025)and National Young Thousand-Talent Scheme to Zhang Zhi-Yong.
文摘The potential translation of bio-inert polymer scaffolds as bone substitutes is limited by the lack of neovascularization upon implantation and subsequently diminished ingrowth of host bone,most likely resulted from the inability to replicate appropriate endogenous crosstalk between cells.Human umbilical vein endothelial cell-derived decellularized extracellular matrix(HdECM),which contains a collection of angiocrine biomolecules,has recently been demonstrated to mediate endothelial cells(ECs)-osteoprogenitors(OPs)crosstalk.We employed the HdECM to create a PCL(polycaprolactone)/fibrin/HdECM(PFE)hybrid scaffold.We hypothesized PFE scaffold could reconstitute a bio-instructive microenvironment that reintroduces the crosstalk,resulting in vascularized bone regeneration.Following implantation in a rat femoral bone defect,the PFE scaffold demonstrated early vascular infiltration and enhanced bone regeneration by microangiography(μ-AG)and micro-computational tomography(μ-CT).Based on the immunofluorescence studies,PFE mediated the endogenous angiogenesis and osteogenesis with a substantial number of type H vessels and osteoprogenitors.In addition,superior osseointegration was observed by a direct host bone-PCL interface,which was likely attributed to the formation of type H vessels.The bio-instructive microenvironment created by our innovative PFE scaffold made possible superior osseointegration and type H vessel-related bone regeneration.It could become an alternative solution of improving the osseointegration of bone substitutes with the help of induced type H vessels,which could compensate for the inherent biological inertness of synthetic polymers.
