Sinusoidal obstruction syndrome (SOS) is one of the severe complications of radiation, anticancer chemotherapy and immunosuppressive agents for transplantation. Autopsy of a case of rapidly progressive, uncontrollable...Sinusoidal obstruction syndrome (SOS) is one of the severe complications of radiation, anticancer chemotherapy and immunosuppressive agents for transplantation. Autopsy of a case of rapidly progressive, uncontrollable severe ascites, without apparent signs of preceding drug toxicity, revealed a tensely enlarged liver and spleen, and 3000 ml of ascites attributed to secondary portal hypertension. Histopathological analysis disclosed sinusoidal endothelial damage and fibrous expansion from central veins. All the foregoing indicated hepatic SOS that needs to be included in the differential diagnosis of progressive ascites in patients without an apparent history of malignancy or transplantation.展开更多
Optical fiber sensors have played a pivotal role in structural health monitoring for over half a century,owing to their inherent advantages such as lightweight design,compactness,immunity to electromagnetic interferen...Optical fiber sensors have played a pivotal role in structural health monitoring for over half a century,owing to their inherent advantages such as lightweight design,compactness,immunity to electromagnetic interference,and their ability to enable distributed sensing.1 Within this diverse range of sensors,Brillouin scattering has emerged as a widely adopted principle for distributed measurements of strain and temperature.展开更多
Optical fibre sensors based on Brillouin scattering have been vigorously studied in the context of structural health monitoring on account of their capacity for distributed strain and temperature measurements.However,...Optical fibre sensors based on Brillouin scattering have been vigorously studied in the context of structural health monitoring on account of their capacity for distributed strain and temperature measurements.However,real-time distributed strain measurement has been achieved only for two-end-access systems;such systems reduce the degree of freedom in embedding the sensors into structures,and furthermore render the measurement no longer feasible when extremely high loss or breakage occurs at a point along the sensing fibre.Here,we demonstrate real-time distributed measurement with an intrinsically one-end-access reflectometry configuration by using a correlation-domain technique.In this method,the Brillouin gain spectrum is obtained at high speed using a voltage-controlled oscillator,and the Brillouin frequency shift is converted into a phase delay of a synchronous sinusoidal waveform;the phase delay is subsequently converted into a voltage,which can be directly measured.When a single-point measurement is performed at an arbitrary position,a strain sampling rate of up to 100 kHz is experimentally verified by detecting locally applied dynamic strain at 1 kHz.When distributed measurements are performed at 100 points with 10 times averaging,a repetition rate of 100 Hz is verified by tracking a mechanical wave propagating along the fibre.Some drawbacks of this ultrahigh-speed configuration,including the reduced measurement accuracy,lowered spatial resolution and limited strain dynamic range,are also discussed.展开更多
Aging degradation and seismic damage of civil infrastructures have become a serious issue for society,and one promising technology for monitoring their conditions is optical fiber sensing.Glass optical fibers have bee...Aging degradation and seismic damage of civil infrastructures have become a serious issue for society,and one promising technology for monitoring their conditions is optical fiber sensing.Glass optical fibers have been predominantly used for the past several decades to develop fiber sensors,but currently polymer or plastic optical fibers(POFs)have also been used extensively to develop advanced fiber sensors because of their unique features,such as high flexibility,large breakage strain,and impact resistance.This review focuses on recently developed distributed and quasi-distributed POF-based sensing techniques based on Rayleigh scattering,Brillouin scattering,and fiber Bragg gratings.展开更多
文摘Sinusoidal obstruction syndrome (SOS) is one of the severe complications of radiation, anticancer chemotherapy and immunosuppressive agents for transplantation. Autopsy of a case of rapidly progressive, uncontrollable severe ascites, without apparent signs of preceding drug toxicity, revealed a tensely enlarged liver and spleen, and 3000 ml of ascites attributed to secondary portal hypertension. Histopathological analysis disclosed sinusoidal endothelial damage and fibrous expansion from central veins. All the foregoing indicated hepatic SOS that needs to be included in the differential diagnosis of progressive ascites in patients without an apparent history of malignancy or transplantation.
文摘Optical fiber sensors have played a pivotal role in structural health monitoring for over half a century,owing to their inherent advantages such as lightweight design,compactness,immunity to electromagnetic interference,and their ability to enable distributed sensing.1 Within this diverse range of sensors,Brillouin scattering has emerged as a widely adopted principle for distributed measurements of strain and temperature.
基金supported by JSPS KAKENHI Grant Numbers 25709032,26630180 and 25007652by research grants from the Iwatani Naoji FoundationSCAT Foundation and the Konica Minolta Science and Technology Foundation.
文摘Optical fibre sensors based on Brillouin scattering have been vigorously studied in the context of structural health monitoring on account of their capacity for distributed strain and temperature measurements.However,real-time distributed strain measurement has been achieved only for two-end-access systems;such systems reduce the degree of freedom in embedding the sensors into structures,and furthermore render the measurement no longer feasible when extremely high loss or breakage occurs at a point along the sensing fibre.Here,we demonstrate real-time distributed measurement with an intrinsically one-end-access reflectometry configuration by using a correlation-domain technique.In this method,the Brillouin gain spectrum is obtained at high speed using a voltage-controlled oscillator,and the Brillouin frequency shift is converted into a phase delay of a synchronous sinusoidal waveform;the phase delay is subsequently converted into a voltage,which can be directly measured.When a single-point measurement is performed at an arbitrary position,a strain sampling rate of up to 100 kHz is experimentally verified by detecting locally applied dynamic strain at 1 kHz.When distributed measurements are performed at 100 points with 10 times averaging,a repetition rate of 100 Hz is verified by tracking a mechanical wave propagating along the fibre.Some drawbacks of this ultrahigh-speed configuration,including the reduced measurement accuracy,lowered spatial resolution and limited strain dynamic range,are also discussed.
基金Japan Society for the Promotion of Science(17H04930,20K22417,21H04555)Noguchi Institute+5 种基金Murata Science FoundationTelecommunications Advancement FoundationYazaki Memorial Foundation for Science and TechnologyTakahashi Industrial and Economic Research FoundationEuropean Regional Development Fundthe Republic of Cyprus through the Research and Innovation Foundation(INTEGRATED/0918/0031)。
文摘Aging degradation and seismic damage of civil infrastructures have become a serious issue for society,and one promising technology for monitoring their conditions is optical fiber sensing.Glass optical fibers have been predominantly used for the past several decades to develop fiber sensors,but currently polymer or plastic optical fibers(POFs)have also been used extensively to develop advanced fiber sensors because of their unique features,such as high flexibility,large breakage strain,and impact resistance.This review focuses on recently developed distributed and quasi-distributed POF-based sensing techniques based on Rayleigh scattering,Brillouin scattering,and fiber Bragg gratings.
