BACKGROUND Angiomyolipoma(AML),the most common benign tumor of the kidney,is usually composed of dysmorphic blood vessels,smooth muscle,and mature adipose tissue.To our knowledge,AML with cystic degeneration has rarel...BACKGROUND Angiomyolipoma(AML),the most common benign tumor of the kidney,is usually composed of dysmorphic blood vessels,smooth muscle,and mature adipose tissue.To our knowledge,AML with cystic degeneration has rarely been documented.Cystic degeneration,hemorrhage,and a lack of fat bring great challenges to the diagnosis.CASE SUMMARY A 60-year-old man with hypertension presented with a 5-year history of cystic mass in his left kidney.He fell 2 mo ago.A preoperative computed tomography(CT)scan showed a mixed-density cystic lesion without macroscopic fat density,the size of which had increased compared with before,probably due to hemorrhage caused by a trauma.Radical nephrectomy was performed.Histopathological studies revealed that the lesion mainly consisted of tortuous,ectatic,and thick-walled blood vessels,mature adipose tissue,and smooth muscle-like spindle cells arranged around the abnormal blood vessels.The tumor cells exhibited positivity for human melanoma black-45,Melan-A,smooth muscle actin,calponin,S-100,and neuron-specific enolase,rather than estrogen receptor,progesterone receptor,CD68,and cytokeratin.The Ki-67 labeling index was less than 5%.The final diagnosis was a fat-poor renal AML(RAML)with prominent cystic degeneration.CONCLUSION When confronting a large renal cystic mass,RAML should be included in the differential diagnosis.展开更多
A new species of the genus Occidozyga is reported from Southern Guangxi,China,based on morphological characters and molecular analyses.Morphological data revealed that the new species,Occidozyga shiwandashanensis sp.n...A new species of the genus Occidozyga is reported from Southern Guangxi,China,based on morphological characters and molecular analyses.Morphological data revealed that the new species,Occidozyga shiwandashanensis sp.nov.,differs from its congeners by a combination of the following characters:(1)medium body size(SVL 25.2−33.8 mm in males,34.9−38.9 mm in females);(2)pale brown dorsum with irregular pale dark spots,especially on head;(3)creamy white ventral surface with brown spots on lateral margin and throat;(4)tongue fleshy,rounded,without notch,(5)tympanum hidden;(6)finger webbing absent and toe webbing full,but fourth toe not webbed to discs;(7)tips of fingers pointed,tips of toes rounded,slightly expanded into disc.The new species occurs on Mt.Shiwandashan and inhabits montane evergreen forests at 500−600 m a.s.l.展开更多
基金Supported by the National Science Foundation of China,No.81860490 and 82160546the Science Foundation of Jiangxi Province,No.20202BBG73027。
文摘BACKGROUND Angiomyolipoma(AML),the most common benign tumor of the kidney,is usually composed of dysmorphic blood vessels,smooth muscle,and mature adipose tissue.To our knowledge,AML with cystic degeneration has rarely been documented.Cystic degeneration,hemorrhage,and a lack of fat bring great challenges to the diagnosis.CASE SUMMARY A 60-year-old man with hypertension presented with a 5-year history of cystic mass in his left kidney.He fell 2 mo ago.A preoperative computed tomography(CT)scan showed a mixed-density cystic lesion without macroscopic fat density,the size of which had increased compared with before,probably due to hemorrhage caused by a trauma.Radical nephrectomy was performed.Histopathological studies revealed that the lesion mainly consisted of tortuous,ectatic,and thick-walled blood vessels,mature adipose tissue,and smooth muscle-like spindle cells arranged around the abnormal blood vessels.The tumor cells exhibited positivity for human melanoma black-45,Melan-A,smooth muscle actin,calponin,S-100,and neuron-specific enolase,rather than estrogen receptor,progesterone receptor,CD68,and cytokeratin.The Ki-67 labeling index was less than 5%.The final diagnosis was a fat-poor renal AML(RAML)with prominent cystic degeneration.CONCLUSION When confronting a large renal cystic mass,RAML should be included in the differential diagnosis.
基金supported by the National Natural Science Foundation of China(32060116)Guangxi Natural Science Foundation,China(2020GXNSFDA238022)。
文摘A new species of the genus Occidozyga is reported from Southern Guangxi,China,based on morphological characters and molecular analyses.Morphological data revealed that the new species,Occidozyga shiwandashanensis sp.nov.,differs from its congeners by a combination of the following characters:(1)medium body size(SVL 25.2−33.8 mm in males,34.9−38.9 mm in females);(2)pale brown dorsum with irregular pale dark spots,especially on head;(3)creamy white ventral surface with brown spots on lateral margin and throat;(4)tongue fleshy,rounded,without notch,(5)tympanum hidden;(6)finger webbing absent and toe webbing full,but fourth toe not webbed to discs;(7)tips of fingers pointed,tips of toes rounded,slightly expanded into disc.The new species occurs on Mt.Shiwandashan and inhabits montane evergreen forests at 500−600 m a.s.l.