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Effect of Yinxieling decoction on PASI,TNF-α and IL-8 in patients with psoriasis vulgaris 被引量:4
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作者 Yong-Jiang Dai yu-yang li +5 位作者 Hui-Ming Zeng Xiong-An liang Zhi-Jie Xie Zhi-Ang Zheng Qin-Hui Pan Yi-Xiong Xing 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2014年第8期668-670,共3页
Objective:To study the effect of Yinxieling decoction on PASI,TNF-α and IL-8 in patients with psoriasis vulgaris.Methods:A total of 120 cases of psoriasis vulgaris were divided into 4 groups according to syndrome dif... Objective:To study the effect of Yinxieling decoction on PASI,TNF-α and IL-8 in patients with psoriasis vulgaris.Methods:A total of 120 cases of psoriasis vulgaris were divided into 4 groups according to syndrome differentiation of TCM and randomized controlled method:wind heat syndrome group(group A).blood stasis syndrome group(group B) blood dryness syndrome group(group C)nd control group(group D)(n=30 per group).Patients in observation groups were treated with Yinxieling decoction,while patients in control group were treated by placebo for 8 weeks.Levels of TNT-α and IL-8 were determined before treatment.4 and 8 weeks after treatment.psoriasis area and severity index score was also performed before and after treatment.Results:psoriasis area and severity index score and serum level of TNF-α,IL-8 were significantly decreased in all groups.The decrease in three observation groups was more significant(P<0.05 or P<0.01),and the decrease in wind heat syndrome group was the most significant(P<0.01).psoriasis area and severity index was positively correlated with TNF-α and IT.-8,respectively(P<0.05).Conclusions:Yinxieling decoction has therapeutical effect on psoriasis vulgaris via regulating TNF-α and IL-8. 展开更多
关键词 Psoriasis vulgaris Yinxieling decoction Syndrome differentiation TNF-Α IL-8
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On-Line Photoionization Mass Spectrometric Study on Behavior of Ammonia Poisoning on H-Form Ultra Stable Y Zeolite for Catalytic Pyrolysis of Polypropylene
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作者 Yi-zun Wang Jiu-zhong Yang +3 位作者 Yang Pan Hao Ma yu-yang li Fei Qi 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2016年第6期681-686,I0001,共7页
在这个工作,热分解光电游离 time-of-flight 团 spectrometry (Py-PI-TOFMS ) 被使用学习为聚丙烯(PP ) 的催化热分解在 H 形式极端稳定的 Y (HUSY ) 沸石上毒害的氨的行为。第一,在 HUSY 上毒害的氨被执行与酸地点的不同力量和数量... 在这个工作,热分解光电游离 time-of-flight 团 spectrometry (Py-PI-TOFMS ) 被使用学习为聚丙烯(PP ) 的催化热分解在 H 形式极端稳定的 Y (HUSY ) 沸石上毒害的氨的行为。第一,在 HUSY 上毒害的氨被执行与酸地点的不同力量和数量获得合适的催化剂。第二,为有各种各样的酸力量的 PP 和 HUSY 的热分解产品的联机光电游离团系列在不同热分解温度被记录。最后,有温度的增加的 PP/HUSY 的各种各样的 pyrolysates 的形成曲线是坚定的。我们的结果显示 PP 的热分解产品的形成温度,收益和选择与 HUSY 的酸力量表明明显的关系。 展开更多
关键词 光电离质谱 催化热解 聚丙烯 氨中毒 超稳Y沸石 行为 质谱法 电离飞行时间质谱
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Parotid mammary analogue secretory carcinoma:A case report and review of literature
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作者 Feng-He Min Jia li +7 位作者 Bo-Qiang Tao Hui-Min liu Zhi-Jing Yang Lu Chang yu-yang li Ying-Kun liu Yi-Wen Qin Wei-Wei liu 《World Journal of Clinical Cases》 SCIE 2021年第16期4052-4061,共10页
BACKGROUND Mammary analogue secretory carcinoma(MASC)is a rare low-grade malignant salivary gland tumor.The morphological and immunohistochemical features of MASC closely resemble those of breast secretory carcinoma.T... BACKGROUND Mammary analogue secretory carcinoma(MASC)is a rare low-grade malignant salivary gland tumor.The morphological and immunohistochemical features of MASC closely resemble those of breast secretory carcinoma.The key characteristics of the lesion are a lack of pain and slow growth.There is no obvious specificity in the clinical manifestations and imaging features.The diagnosis of the disease mainly depends on the detection of the MASC-specific ETV6-NTRK3 fusion gene.CASE SUMMARY This report describes a rare case of a 32-year-old male patient who presented with a gradually growing lesion that was initially diagnosed as breast-like secretory carcinoma of the right parotid gland.Imaging and histological investigations were used to overcome the diagnostic difficulties.The lesion was managed with right parotidectomy,facial nerve preservation,biological patch implantation to restore the resulting defect,and postoperative radiotherapy.On postoperative follow-up,the patient reported a mild facial deformity with no complications,signs of facial paralysis,or Frey’s syndrome.CONCLUSION The imaging and histological diagnostic challenges for MASC are discussed. 展开更多
关键词 Mammary analogue secretory carcinoma Salivary gland IMMUNOHISTOCHEMISTRY Total lobectomy of right parotid gland Case report
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Dynamic changes of inflammation in ligation-induced rat periodontitis model
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作者 Bai-Jie Ren Yue liu +3 位作者 yu-yang li Xin-Ying Zou Chen Kong Lei Wang 《Journal of Hainan Medical University》 2021年第2期6-10,共5页
Objective:To study the dynamic changes of inflammation in rat models of periodontitis induced by ligation.Methods:Twenty-one healthy male SD rats were selected and randomly divided into 7 groups,namely normal control ... Objective:To study the dynamic changes of inflammation in rat models of periodontitis induced by ligation.Methods:Twenty-one healthy male SD rats were selected and randomly divided into 7 groups,namely normal control group and ligation group A-F(the ligation group A-F were ligated 1,3,5,7,14 and 21 days respectively,and then sacrificed).In addition to the normal control group,ligature was used to ligate the neck of the right maxillary first molar.The experimental periodontitis model was established in rats.By observing the changes in rat body weight within 21 days,we explored the intervention of ligature wires on inflammation.The impact of the process,through monitoring the debris index simplified(DIS),Sulcus Bleeding Index(SBI),Tooth Mobility(TM),to evaluate the periodontal inflammation of the target tooth within 21 days of ligation.In addition,in order to more accurately assess the dynamic changes of the alveolar bone during the inflammatory phase,we use CBCT Observe the alveolar bone resorption.Results:The body weight of the ligation group decreased during the 3 days after ligation,and compared with the normal control group,there was no statistically significant difference in body weight growth rate in the ligation group from 3 to 21 days(P≥0.05),indicating that due to the intervention of the ligation wire,the rat will have a 3-day adaptability phenomenon.The ligation of silk after day will not affect the growth and development of rats.The DIS on the ligated side was higher than that of the normal control on the first,third,fifth,and seventh days after the ligation.The side increased significantly(P<0.05),and the DIS value increased in the first 3 days,and gradually decreased on the 5th day,until the 21st day after ligation,compared with the normal control group,the difference was not statistically significant(P≥0.05);SDI on the ligation side increased significantly on the 5th day,and gradually decreased after reaching the peak on the 7th day(P<0.05),until there was no statistical difference between the ligation side and the normal control group on the 21st day(P≥0.05);The day began to change and gradually increased until the 21st day,which was statistically significant compared with the normal control group(P<0.05);the CEJ-ABC distance of the ligation group A,B,and C was not statistically significant compared with the normal controlgroup(P>0.05),the CEJ-ABC distance of the ligated group D,E,and F was significantly higher than that of the normal control group(P<0.05),and bone resorption was more significant in group F compared with D and E groups(P<0.01).Conclusion:Three days after the ligation of the ligature,it affects the molar eating in rats,and induces inflammation.Ligation-induced experimental periodontitis is in the acute inflammatory phase during 3-7 days of ligation,and turns to chronic inflammatory phase in 14-21 days.Our study provides a more precise definition of the occurrence and development of ligation-induced periodontitis in rats,which provides a new direction for the subsequent study of periodontitis models and provides a basis for better and more accurate clinical research. 展开更多
关键词 PERIODONTITIS Debris index simplified Sulcus bleeding index Tooth mobility
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环己烷在射流搅拌反应器中的低温氧化动力学初探:实验和动力学模型研究(英文) 被引量:3
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作者 邹家标 李伟 +4 位作者 叶莉莉 张晓愿 李玉阳 杨玖重 齐飞 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2018年第4期537-546,615,共11页
本文报道了500-742K下环己烷在射流搅拌反应器中的低温氧化.应用同步辐射真空紫外光电离质谱(SVUV—PIMS)对氧化物种进行了定性和定量测量.探测到的氧化物种有主要产物、环烯烃以及含氧产物,包括活泼的过氧化物和高氧化合物.与烷... 本文报道了500-742K下环己烷在射流搅拌反应器中的低温氧化.应用同步辐射真空紫外光电离质谱(SVUV—PIMS)对氧化物种进行了定性和定量测量.探测到的氧化物种有主要产物、环烯烃以及含氧产物,包括活泼的过氧化物和高氧化合物.与烷烃相比,环己烷的低温氧化过程中观察到更窄的低温反应区(-80K).此外,基于CNRS模型[(Coinbust.Flame 160,2319(2013)1发展了一个环己烷模型。本模型与前人模型相比能够更好地预测实验结果.利用模型开展的动力学分析表明,1,5-氢转移在环己烷低温链分支过程中主导一次和二次加氧产物的关键异构化反应.由于链抑制步和链传递步的竞争,如环己基加氧气的反应和环己基过氧自由基的分解反应均可产生环己烯和HO2,或者经环己基过氧化自由基产生5-己烯-1-醛和OH,导致链分支过程被抑制,从而引发了环己烷低温氧化中的负温度系数效应. 展开更多
关键词 环己烷 低温氧化 SVUV-PIMS 燃烧反应动力学模型 负温度系数效应
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Effect of pharmacological intervention on MIP-1α,MIP-1β and MCP-1 expression in patients with psoriasis vulgaris 被引量:7
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作者 Yong-Jiang Dai yu-yang li +5 位作者 Hui-Ming Zeng Xiong-An liang Zhi-Jie Xie Zhi-Ang Zheng Qin-Hui Pan Yi-Xiong Xing 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2014年第7期582-584,共3页
Objective:To detect the expression level of macrophage inflammatory protein-1(MIP-1)α,MIP-1βand monocyte chemoattractant protein-1(MCP-1)in with psoriasis vulgaris and explore the role in the pathogenesis of psorias... Objective:To detect the expression level of macrophage inflammatory protein-1(MIP-1)α,MIP-1βand monocyte chemoattractant protein-1(MCP-1)in with psoriasis vulgaris and explore the role in the pathogenesis of psoriasis vulgaris.Methods:The level of MIP-1α,MIP-1βand MCP-1 in peripheral blood from 50 patients with psoriasis vulgaris and 50 normal controls were measured by enzyme linked immunosorbent assay.The correlation with psoriasis area and severity index(PASI)was analyzed.The level of MIP-1α,MIP-1βand MCP-1 was compared between psoriasis vulgaris patients at active stage and resting stage.And the change in MIP-1α,MIP-1βand MCP-1 before and after therapy was also observed.Results:The content of MIP-1α,MIP-1βand MCP-1 in patients with psoriasis vulgaris was(1342.78±210.30),(175.28±28.18)and(266.86±32.75)ng/L,respectively,significantly higher than those in control group(P<0.05).The expression level of MIP-1α,MIP-1βand MCP-1 in peripheral blood of patients with psoriasis vulgaris was positively correlated wilh PASI(P<0.01).After acitretin therapy,expression level of MIP-1α,MIP-1βand MCP-1 in peripheral blood of patients with psoriasis vulgaris was significantly decreased.Conclusions:Chemokine factor MIP-1α,MIP-1βand MCP-1 may be involved in the pathogenesis of psoriasis vulgaris. 展开更多
关键词 Macrophage inflammatory protein-1 MONOCYTE CHEMOATTRACTANT protein-1 Psoriasis VULGARIS
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Gabor-CNN for object detection based on small samples 被引量:4
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作者 Xiao-dong Hu Xin-qing Wang +5 位作者 Fan-jie Meng Xia Hua Yu-ji Yan yu-yang li Jing Huang Xun-lin Jiang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2020年第6期1116-1129,共14页
Object detection models based on convolutional neural networks(CNN)have achieved state-of-the-art performance by heavily rely on large-scale training samples.They are insufficient when used in specific applications,su... Object detection models based on convolutional neural networks(CNN)have achieved state-of-the-art performance by heavily rely on large-scale training samples.They are insufficient when used in specific applications,such as the detection of military objects,as in these instances,a large number of samples is hard to obtain.In order to solve this problem,this paper proposes the use of Gabor-CNN for object detection based on a small number of samples.First of all,a feature extraction convolution kernel library composed of multi-shape Gabor and color Gabor is constructed,and the optimal Gabor convolution kernel group is obtained by means of training and screening,which is convolved with the input image to obtain feature information of objects with strong auxiliary function.Then,the k-means clustering algorithm is adopted to construct several different sizes of anchor boxes,which improves the quality of the regional proposals.We call this regional proposal process the Gabor-assisted Region Proposal Network(Gabor-assisted RPN).Finally,the Deeply-Utilized Feature Pyramid Network(DU-FPN)method is proposed to strengthen the feature expression of objects in the image.A bottom-up and a topdown feature pyramid is constructed in ResNet-50 and feature information of objects is deeply utilized through the transverse connection and integration of features at various scales.Experimental results show that the method proposed in this paper achieves better results than the state-of-art contrast models on data sets with small samples in terms of accuracy and recall rate,and thus has a strong application prospect. 展开更多
关键词 Deep learning Convolutional neural network Small samples Gabor convolution kernel Feature pyramid
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Experimental Study of Premixed Stoichiometric Ethylene/Oxygen/Argon Flame
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作者 Qing Zhang yu-yang li +3 位作者 Zhen-yu Tian Tai-chang Zhang Jing Wang Fei Qi 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 北大核心 2006年第5期379-385,共7页
在有 stoichiometric 等价比率(=1 ) 的 2.667 kPa 的 premixed 乙烯 / 氧 / 氩火焰的全面试验性的研究与悦耳的同步加速器光电游离和分子横梁的采样团 spectrometry 技术被执行。在火焰的最观察的种类的异构体被光电游离效率系列的大... 在有 stoichiometric 等价比率(=1 ) 的 2.667 kPa 的 premixed 乙烯 / 氧 / 氩火焰的全面试验性的研究与悦耳的同步加速器光电游离和分子横梁的采样团 spectrometry 技术被执行。在火焰的最观察的种类的异构体被光电游离效率系列的大小明白地识别,例如 C <SUB>3</SUB > H <SUB>4</SUB>, C <SUB>2</SUB > H <SUB>4</SUB > O 和 C <SUB>4</SUB > H <SUB>4</SUB> 。直到 C <SUB>7</SUB 的种类的鼹鼠部分侧面 > H <SUB>8</SUB> 被在电离阀值,和火焰温度侧面附近在选择光子精力扫描炉子位置测量被使用 Pt/Pt-13%Rh 热电偶获得。与以前的研究相比,很多新火焰种类: C <SUB>3</SUB > H <SUB>2</SUB>, C <SUB>3</SUB > H <SUB>3</SUB>, C <SUB>3</SUB > H <SUB>5</SUB>, C <SUB>2</SUB > H <SUB>6</SUB > O , C <SUB>4</SUB > H <SUB>2</SUB>, C <SUB>4</SUB > H <SUB>4</SUB>, C <SUB>4</SUB > H <SUB>6</SUB>, C <SUB>3</SUB > H <SUB>4</SUB > O , C <SUB>3</SUB > H <SUB>6</SUB > O , C <SUB>3</SUB > H <SUB>8</SUB > O , C <SUB>5</SUB > H <SUB>6</SUB>, C <SUB>4</SUB > H <SUB>8</SUB > O 和 C <SUB>7</SUB > H <SUB>8</SUB>,被观察。在火焰的一系列自由激进分子被检测是 CH <SUB>3</SUB>, C <SUB>2</SUB > H <SUB>3</SUB>, C <SUB>2</SUB > H <SUB>5</SUB>, HCO, C <SUB>3</SUB > H <SUB>3</SUB> 和 C <SUB>3</SUB > H <SUB>5</SUB> 。基于试验性的工作,减少的反应机制包括 40 种类和 223 反应被开发。建模并且大小为主要种类和大多数中介同意很好。一个详细运动模型为这火焰被需要。 展开更多
关键词 预混乙烯/氧气/氩气火焰 可调谐同步辐射光电离 反应机理
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Patients’awareness about their own breast cancer characteristics
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作者 Chong Geng Guo-Jun Lu +1 位作者 Jing Zhu yu-yang li 《World Journal of Clinical Cases》 SCIE 2021年第24期7043-7052,共10页
BACKGROUND Patients’knowledge about the characteristics of their own cancer could be an important factor for understanding treatment regimens and adhering to therapies.However,to date nothing is known about the aware... BACKGROUND Patients’knowledge about the characteristics of their own cancer could be an important factor for understanding treatment regimens and adhering to therapies.However,to date nothing is known about the awareness among Chinese breast cancer patients about the characteristics of their own tumors.AIM To investigate how much knowledge that Chinese breast cancer patients have about their tumor characteristics and the impact of health and education literacy on the acquisition of such information.METHODS The survey was administered to patients who were diagnosed with breast cancer from 2017 to 2019 in three hospitals in China,and who came in for regular followup on an outpatient basis.We collected responses from 226 respondents who were asked about their cancer characteristics(stage,grade,and estrogen receptor status and human epidermal growth factor receptor 2 status of the cancer),and evaluated the correctness by comparing with their medical records.Logistic regression was used to assess the probability of knowing and of correctly answering questions.We also analyzed the association between our findings and the level of the patient’s education and their health literacy.RESULTS Overall,20.80%to 57.96%of the patients reported knowing about the characteristics of breast cancer;of these,10.18%to 46.46%reported these characteristics correctly.Education,age,and health literacy were all significantly associated with awareness rate,and with the level to which this information was accurate.CONCLUSION Breast cancer patients in China know little about their disease,and better education aimed at improving their knowledge about cancer characteristics is urgently needed.The low level of awareness could represent a deficiency of communication between surgeons and patients,which may be one of the reasons why medical disputes occur in China. 展开更多
关键词 Breast cancer AWARENESS CHARACTERISTICS Health literacy EDUCATION
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The first photometric analysis and period investigation of the K-type W UMa type binary system V0842 Cep
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作者 yu-yang li Kai li Yuan liu 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2021年第5期201-206,共6页
V0842 Cep is a W UMa-type binary star that has been neglected since its discovery.We analysed the V RcIc light curves,obtained by the 1 m telescope at Weihai Observatory of Shandong University,using the Wilson-Devinne... V0842 Cep is a W UMa-type binary star that has been neglected since its discovery.We analysed the V RcIc light curves,obtained by the 1 m telescope at Weihai Observatory of Shandong University,using the Wilson-Devinney code.V0842 Cep was found to be a shallow contact binary system(f=8.7%)with a mass ratio of 2.281.Because its orbital inclination is greater than 80◦,the photometric results are reliable.A period study is included which reveals a continually decreasing orbital period(dp/dt=1.50(±0.42)×10^(−7)d y^(r−1)).This trend could be attributed to the angular momentum loss via stellar wind. 展开更多
关键词 stars:binaries:close stars:binaries:eclipsing stars:individual(V0842 Cep)
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Screening for candidate genes related to breast cancer with cDNA microarray analysis
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作者 Yu-Juan Xiang Qin-Ye Fu +8 位作者 Zhong-Bing Ma De-Zong Gao Qiang Zhang yu-yang li liang li Lu liu Chun-Miao Ye Zhi-Gang Yu Ming-Ming Guo 《Chronic Diseases and Translational Medicine》 2015年第2期-,共8页
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