[Objective] This study aimed to screen yeast strains suitable for high temperature processing of formulated biological feed. [Method] High temperature resistance and culture conditions of six yeast strains were invest...[Objective] This study aimed to screen yeast strains suitable for high temperature processing of formulated biological feed. [Method] High temperature resistance and culture conditions of six yeast strains were investigated. [Result] Two yeast strains resistant to high temperature( 45 ℃) with high viable cell number( 108 cells / ml) were screened,including DQFC2117-1 and DQFC2122-2. [Conclusion] Strains DQFC2117-1 and DQFC2122-2 could be used as high temperature resistant yeast strains for processing of formulated biological feed.展开更多
Today we are in a technologically explosive information society. The cross-</span></span><span style="white-space:normal;"><span style="font-family:""> </span&g...Today we are in a technologically explosive information society. The cross-</span></span><span style="white-space:normal;"><span style="font-family:""> </span></span><span style="white-space:normal;"><span style="font-family:"">border integration of manufacturing and construction is prefabricated buildings. The cross-border integration of construction and IT is BIM technology, and the emergence of BIM technology provides new ideas for prefabricated building, and the integration of prefabricated building and BIM technology realizes the construction industrialization. This paper studies the application of BIM technology in prefabricated buildings, including the design phase, construction and assembly phase, operation and maintenance phase, and application analysis of related software, so as to improve the high efficiency, high quality and high precision development of prefabricated projects, and promote domestic green environmental protection. The development of the construction industry provides reference value for the application of BIM technology in prefabricated buildings.展开更多
In the rapid development of modern cities, the construction of green low-car</span><span style="white-space:normal;font-size:10pt;font-family:"">- </span><span style="whit...In the rapid development of modern cities, the construction of green low-car</span><span style="white-space:normal;font-size:10pt;font-family:"">- </span><span style="white-space:normal;font-size:10pt;font-family:"">bon livable cities and the realization of energy-saving and beautification of buildings </span><span style="white-space:normal;font-size:10pt;font-family:"">are</span><span style="white-space:normal;font-size:10pt;font-family:""> now being strongly promoted and ha</span><span style="white-space:normal;font-size:10pt;font-family:"">ve</span><span style="white-space:normal;font-size:10pt;font-family:"">become an important indicator of urban development. With the implementation of green building and BIM technology, the combination of BIM technology with green building is a new momentum in the development of the construction industry. The application of BIM can make the quantitative management of green buildings in the whole life cycle, get rid of the shackles of traditional models, make the design and construction process more accurate, and also make the whole pro</span><span style="white-space:normal;font-size:10pt;font-family:"">cess of green buildings more standardized. Among them, the core of BIM is the information model, and the core of green building is: low energy consum</span><span style="white-space:normal;font-size:10pt;font-family:"">ption, green and sustainable. This paper firstly explains the concepts and advantages of BIM technology and green building, and separately elaborates the significance of using both in the construction field. Secondly, the current development status of BIM technology and green building is obtained by studying and analyzing the development status and connection between them. Finally, combining BIM technology in the whole life cycle of green building, analyzing the current situation and advantages and disadvantages of using the combination of green building and BIM in actual engineering, clarifying the importance of using BIM in the whole life cycle of green building, and highlighting the combination of BIM technology and the whole life cycle of green building as an important tool for the future development of the construction industry.展开更多
Motivated by the fascinating progresses in the cold atom experiments and theories,especially the artificial gauge field induced spin–orbit coupling of neutral atoms,we present a novel dispersion of neutral atoms carr...Motivated by the fascinating progresses in the cold atom experiments and theories,especially the artificial gauge field induced spin–orbit coupling of neutral atoms,we present a novel dispersion of neutral atoms carrying a non-vanishing magnetic moment in a special gauge field,an external electric field of dark-soliton shaped profile.By means of WKB approximation,we obtain discrete quantized landau-like energy levels,which is instructive for the quantum Hall effect of neutral particles.The observability of the results is also discussed.展开更多
Reservoir plays an important role in the allocation and rational use of water resources, especially water resources in China are centrally distributed in the western region, and large reservoirs should be built to mee...Reservoir plays an important role in the allocation and rational use of water resources, especially water resources in China are centrally distributed in the western region, and large reservoirs should be built to meet the people’s livelihood needs of each region.</span><span style="white-space:normal;font-size:10pt;font-family:""> </span><span style="white-space:normal;font-size:10pt;font-family:"">The construction of large reservoirs has numerous risks, the clarity of these risks helps us to better plan and make decisions before implementing the project.</span><span style="white-space:normal;font-size:10pt;font-family:""> </span><span style="white-space:normal;font-size:10pt;font-family:"">Search through literature reading and professional information, determined 11 risk factors in the construction phase of the reservoir construction project case, construct a risk influencing factor system under the application of ISM (Interpretative Structural Modeling). Studies have shown that the risks of strategic guidelines and policies and changes in infrastructure planning have the deepest impact on construction risk management. Among them, the strategic policy risk is the root impact, and the impact of the infrastructure planning change risk has a far-reaching impact. Through the above conclusions, providing management countermeasures and suggestions for the risk control of reservoir construction.展开更多
Construction project management is an important aspect of civil engineering construction. How to use scientific and efficient methods to effectively man</span><span style="font-family:Verdana;">a...Construction project management is an important aspect of civil engineering construction. How to use scientific and efficient methods to effectively man</span><span style="font-family:Verdana;">age construction projects is the focus of construction project development un</span><span style="font-family:Verdana;">der the current situation. This article discusses the application of fuzzy mathematics in construction project management. The study found that in the process of construction project management, it was found that a single fuzzy </span><span style="font-family:Verdana;">mathematical method was difficult to adapt to the current complex and cha</span><span style="font-family:Verdana;">ngeable construction projects. Combining fuzzy mathematics with other man</span><span style="font-family:Verdana;">agement methods and computer applications can better simplify complex</span><span style="font-family:Verdana;"> things, reduce human subjectivity, increase calculation speed, and achieve a combination of qualitative and quantitative research;selection of optimization schemes and risk assessment, etc. All have a good effect, and can better </span><span style="font-family:Verdana;">deal with possible or uncertain things and emergencies in the process of pr</span><span style="font-family:Verdana;">oject management. At the same time, combining fuzzy mathematics with heuristic algorithms or meta-heuristic algorithms can make research more objective, improve management efficiency and calculation speed.展开更多
The administration time is a critical but long-neglected point in cell therapy based on macrophages because the incorrect time of macrophage administration could result in diverse outcomes regarding the same macrophag...The administration time is a critical but long-neglected point in cell therapy based on macrophages because the incorrect time of macrophage administration could result in diverse outcomes regarding the same macrophage therapy.In this work,the second near-infrared(NIR-II)fluorescence imaging in vivo tracking of M2 macrophages during a pro-healing therapy in the mice model of rotator cuff injury revealed that the behavior of administrated macrophages was influenced by the timing of their administration.The delayed cell therapy(DCT)group had a longer retention time of injected M2 macrophages in the repairing tissue than that in the immediate cell therapy(ICT)group.Both Keller-Segel model and histological analysis further demonstrated that DCT altered the chemotaxis of M2 macrophages and improved the healing outcome of the repaired structure in comparison with ICT.Our results offer a possible explanation of previous conflicting results on reparative cell therapy and provoke reconsideration of the timing of these therapies.展开更多
Lithium(Li)metal is a potential anode for high-energy-density batteries because of its low potential and ultrahigh capacity.Nevertheless,the Li dendrites formation,the ununiform Li deposition,and the growth of Li dend...Lithium(Li)metal is a potential anode for high-energy-density batteries because of its low potential and ultrahigh capacity.Nevertheless,the Li dendrites formation,the ununiform Li deposition,and the growth of Li dendrites hamper its application,especially under high deposition capacity/high rate.Here,a spatially controlled Li deposition mode with array-oriented morphology is achieved based on the novel mixed ion/electron-conducting Li_(x)Cu_(y)P_(z) arrays constructed on Cu foil,which can be facile fabricated via an in-situ transformation of metal phosphide.Theoretic calculations indicate the excellent lithiophilicity and low Li diffusion barrier of the arrays,especially for the Li_(2)CuP phase,which are conducive to ho-mogenizing the Li nucleation/deposition of Li.Moreover,such mixed conducting arrays promote fast Li+diffusion via the continuous Li+pathways as well as modulate the Li+flux/electric field.Furthermore,the arrays with enlarged specific surface area and open spaces reduce the local current density and alle-viate the volume fluctuation of Li.Consequently,a dendrite-free Li anode is obtained under a high rate(20 mA cm^(–2))or a high deposition capacity(10 mAh cm^(–2)).In addition,even if the negative/positive ratio reduces to only 1.1,the full cells still perform outstanding stability for over 200 cycles.This work empha-sizes the importance of the design of the framework in terms of the intrinsic properties and structure and reveals a pathway for developing Li metal batteries.展开更多
Subsoiling has been widely used all over the world as an important operation method of no-tillage farming.For energy-saving and life-extension,the tillage resistance and wear-corrosion of subsoilers have attracted wid...Subsoiling has been widely used all over the world as an important operation method of no-tillage farming.For energy-saving and life-extension,the tillage resistance and wear-corrosion of subsoilers have attracted wide attention.In this study,the tillage resistance,soil disturbance,wear and corrosion of subsoiler with S-T-SK-2#biomimetic structures(S means subsoiler;T means tine;SK means shank;2#,h/s=0.57,h=5 mm andα=45°.)and self-healing coating under two seasons,two locations with different soil properties(black loam and clay soil)and subsoiling speeds(2 km/h and 3.6 km/h)were investigated.The soil moisture content and compactness affected the tillage resistance and wear-corrosion.The tillage resistance and degree of corrosion on all subsoilers were much larger in clay soil than that in black loam soil.Compared with S-T-SK-2#,the tillage reduction rate of C-S-T-SK-2#(S-T-SK-2#with self-healing coating)was up to 14.32%in clay soil under the speed of 2 km/h.The significance tests of regression equation results showed that subsoiler type and soil properties had a significant impact on soil disturbance coefficient,swelling of total soil layer,bulkiness of the plough pan.It is of a guiding significance for the analysis of soil disturbance.Synergism mechanism of subsoiler coupling with biomimetic structures and self-healing coating was analyzed in following.It depicted the guiding effect of biomimetic structure and the shield function of self-healing coating,resulting in anticorrosion and wear resistance of subsoiler.展开更多
Metal-organic frameworks(MOFs) have been emerging as important multifunctional hybrid materials, not only due to the diversify framework architectures, but also contribute to the rich interactions among metals, ligand...Metal-organic frameworks(MOFs) have been emerging as important multifunctional hybrid materials, not only due to the diversify framework architectures, but also contribute to the rich interactions among metals, ligands and guests. Nitro explosives have important influences for environmental protection and national homeland security. In this review, a brief description of luminescent MOFs is presented, accompanied by a short comment on the four types of metal-based luminescent MOFs as sensing materials for nitro explosives detection. Then the trends and challenges of luminescent MOFs as sensing materials for nitro explosives are also prospected.展开更多
Dear editor,The prognosis of metastatic renal cell carcinoma(mRCC)has been significantly improvedwith the development and widespread use of vascular endothelial growth factor(VEGF)pathway inhibitors and mammalian targ...Dear editor,The prognosis of metastatic renal cell carcinoma(mRCC)has been significantly improvedwith the development and widespread use of vascular endothelial growth factor(VEGF)pathway inhibitors and mammalian target of rapamycin(mTOR)pathway inhibitors[1].For the past decade,the standard of care utilized in the first-line setting was VEGF-targeted therapies.Recently,the mRCC treatment landscape has rapidly changed with the exploration of combinations of immune checkpoint inhibitors(ICIs)and anti-VEGF agents[2,3].展开更多
基金Supported by Special Fund for Basic and Applied Research from the Finance Department of Heilongjiang Province
文摘[Objective] This study aimed to screen yeast strains suitable for high temperature processing of formulated biological feed. [Method] High temperature resistance and culture conditions of six yeast strains were investigated. [Result] Two yeast strains resistant to high temperature( 45 ℃) with high viable cell number( 108 cells / ml) were screened,including DQFC2117-1 and DQFC2122-2. [Conclusion] Strains DQFC2117-1 and DQFC2122-2 could be used as high temperature resistant yeast strains for processing of formulated biological feed.
文摘Today we are in a technologically explosive information society. The cross-</span></span><span style="white-space:normal;"><span style="font-family:""> </span></span><span style="white-space:normal;"><span style="font-family:"">border integration of manufacturing and construction is prefabricated buildings. The cross-border integration of construction and IT is BIM technology, and the emergence of BIM technology provides new ideas for prefabricated building, and the integration of prefabricated building and BIM technology realizes the construction industrialization. This paper studies the application of BIM technology in prefabricated buildings, including the design phase, construction and assembly phase, operation and maintenance phase, and application analysis of related software, so as to improve the high efficiency, high quality and high precision development of prefabricated projects, and promote domestic green environmental protection. The development of the construction industry provides reference value for the application of BIM technology in prefabricated buildings.
文摘In the rapid development of modern cities, the construction of green low-car</span><span style="white-space:normal;font-size:10pt;font-family:"">- </span><span style="white-space:normal;font-size:10pt;font-family:"">bon livable cities and the realization of energy-saving and beautification of buildings </span><span style="white-space:normal;font-size:10pt;font-family:"">are</span><span style="white-space:normal;font-size:10pt;font-family:""> now being strongly promoted and ha</span><span style="white-space:normal;font-size:10pt;font-family:"">ve</span><span style="white-space:normal;font-size:10pt;font-family:"">become an important indicator of urban development. With the implementation of green building and BIM technology, the combination of BIM technology with green building is a new momentum in the development of the construction industry. The application of BIM can make the quantitative management of green buildings in the whole life cycle, get rid of the shackles of traditional models, make the design and construction process more accurate, and also make the whole pro</span><span style="white-space:normal;font-size:10pt;font-family:"">cess of green buildings more standardized. Among them, the core of BIM is the information model, and the core of green building is: low energy consum</span><span style="white-space:normal;font-size:10pt;font-family:"">ption, green and sustainable. This paper firstly explains the concepts and advantages of BIM technology and green building, and separately elaborates the significance of using both in the construction field. Secondly, the current development status of BIM technology and green building is obtained by studying and analyzing the development status and connection between them. Finally, combining BIM technology in the whole life cycle of green building, analyzing the current situation and advantages and disadvantages of using the combination of green building and BIM in actual engineering, clarifying the importance of using BIM in the whole life cycle of green building, and highlighting the combination of BIM technology and the whole life cycle of green building as an important tool for the future development of the construction industry.
基金Project supported by China Scholarship Council,Shanxi Province Natural Science Foundation,China(Grant No.201601D011009)the Enterprise Project(Grant No.01110116100051)+1 种基金Shanxi 1331KSC and 111 Project(Grant No.D18001)the National Natural Science Foundation of China(Grant Nos.11404415 and 61873154)
文摘Motivated by the fascinating progresses in the cold atom experiments and theories,especially the artificial gauge field induced spin–orbit coupling of neutral atoms,we present a novel dispersion of neutral atoms carrying a non-vanishing magnetic moment in a special gauge field,an external electric field of dark-soliton shaped profile.By means of WKB approximation,we obtain discrete quantized landau-like energy levels,which is instructive for the quantum Hall effect of neutral particles.The observability of the results is also discussed.
文摘Reservoir plays an important role in the allocation and rational use of water resources, especially water resources in China are centrally distributed in the western region, and large reservoirs should be built to meet the people’s livelihood needs of each region.</span><span style="white-space:normal;font-size:10pt;font-family:""> </span><span style="white-space:normal;font-size:10pt;font-family:"">The construction of large reservoirs has numerous risks, the clarity of these risks helps us to better plan and make decisions before implementing the project.</span><span style="white-space:normal;font-size:10pt;font-family:""> </span><span style="white-space:normal;font-size:10pt;font-family:"">Search through literature reading and professional information, determined 11 risk factors in the construction phase of the reservoir construction project case, construct a risk influencing factor system under the application of ISM (Interpretative Structural Modeling). Studies have shown that the risks of strategic guidelines and policies and changes in infrastructure planning have the deepest impact on construction risk management. Among them, the strategic policy risk is the root impact, and the impact of the infrastructure planning change risk has a far-reaching impact. Through the above conclusions, providing management countermeasures and suggestions for the risk control of reservoir construction.
文摘Construction project management is an important aspect of civil engineering construction. How to use scientific and efficient methods to effectively man</span><span style="font-family:Verdana;">age construction projects is the focus of construction project development un</span><span style="font-family:Verdana;">der the current situation. This article discusses the application of fuzzy mathematics in construction project management. The study found that in the process of construction project management, it was found that a single fuzzy </span><span style="font-family:Verdana;">mathematical method was difficult to adapt to the current complex and cha</span><span style="font-family:Verdana;">ngeable construction projects. Combining fuzzy mathematics with other man</span><span style="font-family:Verdana;">agement methods and computer applications can better simplify complex</span><span style="font-family:Verdana;"> things, reduce human subjectivity, increase calculation speed, and achieve a combination of qualitative and quantitative research;selection of optimization schemes and risk assessment, etc. All have a good effect, and can better </span><span style="font-family:Verdana;">deal with possible or uncertain things and emergencies in the process of pr</span><span style="font-family:Verdana;">oject management. At the same time, combining fuzzy mathematics with heuristic algorithms or meta-heuristic algorithms can make research more objective, improve management efficiency and calculation speed.
基金the approval of ethics by Ethics Committee of Fudan University(No.202208005Z)supported by the National Natural Science Foundation of China(Nos.81972129,82072521,82111530200)+1 种基金Shanghai Talent Development Funding Scheme(No.2020080)Shanghai Committee of Science and Technology(Nos.22DZ2204900,23ZR1445700)。
文摘The administration time is a critical but long-neglected point in cell therapy based on macrophages because the incorrect time of macrophage administration could result in diverse outcomes regarding the same macrophage therapy.In this work,the second near-infrared(NIR-II)fluorescence imaging in vivo tracking of M2 macrophages during a pro-healing therapy in the mice model of rotator cuff injury revealed that the behavior of administrated macrophages was influenced by the timing of their administration.The delayed cell therapy(DCT)group had a longer retention time of injected M2 macrophages in the repairing tissue than that in the immediate cell therapy(ICT)group.Both Keller-Segel model and histological analysis further demonstrated that DCT altered the chemotaxis of M2 macrophages and improved the healing outcome of the repaired structure in comparison with ICT.Our results offer a possible explanation of previous conflicting results on reparative cell therapy and provoke reconsideration of the timing of these therapies.
基金This work was supported by the National Science Foundation of Tianjin(No.20JCQNJC00500)。
文摘Lithium(Li)metal is a potential anode for high-energy-density batteries because of its low potential and ultrahigh capacity.Nevertheless,the Li dendrites formation,the ununiform Li deposition,and the growth of Li dendrites hamper its application,especially under high deposition capacity/high rate.Here,a spatially controlled Li deposition mode with array-oriented morphology is achieved based on the novel mixed ion/electron-conducting Li_(x)Cu_(y)P_(z) arrays constructed on Cu foil,which can be facile fabricated via an in-situ transformation of metal phosphide.Theoretic calculations indicate the excellent lithiophilicity and low Li diffusion barrier of the arrays,especially for the Li_(2)CuP phase,which are conducive to ho-mogenizing the Li nucleation/deposition of Li.Moreover,such mixed conducting arrays promote fast Li+diffusion via the continuous Li+pathways as well as modulate the Li+flux/electric field.Furthermore,the arrays with enlarged specific surface area and open spaces reduce the local current density and alle-viate the volume fluctuation of Li.Consequently,a dendrite-free Li anode is obtained under a high rate(20 mA cm^(–2))or a high deposition capacity(10 mAh cm^(–2)).In addition,even if the negative/positive ratio reduces to only 1.1,the full cells still perform outstanding stability for over 200 cycles.This work empha-sizes the importance of the design of the framework in terms of the intrinsic properties and structure and reveals a pathway for developing Li metal batteries.
基金This work was supported by Natural Science Foundation of Zhejiang Province(Grant No.Q23E050025)Huzhou Key Research and Development Project(Grant No.2022ZD2068)+5 种基金Scientific Research Fund of Zhejiang Provincial Education Department(Grant No.Y202145948)Huzhou University School-Level Scientific Research Projects(Grant No.2021XJKJ01)Cross Project of Zhejiang Fubai Material Technology Co.,Ltd(Grant No.HK33176)Cross Project of Zhejiang Aobo Quartz Technology Co.,Ltd(Grant No.HK33312),Zhejiang Province Basic Public Welfare Research Program(Grant No.LGG21E010002)Unveiling the Commander Special Plan for Scientific and Technological Research of Liaoning Province(Grant No.2021JH1/10400039)Science and Technology Research and Industrialization Project of Liaoning Province(Grant No.2020JH2/10200024).
文摘Subsoiling has been widely used all over the world as an important operation method of no-tillage farming.For energy-saving and life-extension,the tillage resistance and wear-corrosion of subsoilers have attracted wide attention.In this study,the tillage resistance,soil disturbance,wear and corrosion of subsoiler with S-T-SK-2#biomimetic structures(S means subsoiler;T means tine;SK means shank;2#,h/s=0.57,h=5 mm andα=45°.)and self-healing coating under two seasons,two locations with different soil properties(black loam and clay soil)and subsoiling speeds(2 km/h and 3.6 km/h)were investigated.The soil moisture content and compactness affected the tillage resistance and wear-corrosion.The tillage resistance and degree of corrosion on all subsoilers were much larger in clay soil than that in black loam soil.Compared with S-T-SK-2#,the tillage reduction rate of C-S-T-SK-2#(S-T-SK-2#with self-healing coating)was up to 14.32%in clay soil under the speed of 2 km/h.The significance tests of regression equation results showed that subsoiler type and soil properties had a significant impact on soil disturbance coefficient,swelling of total soil layer,bulkiness of the plough pan.It is of a guiding significance for the analysis of soil disturbance.Synergism mechanism of subsoiler coupling with biomimetic structures and self-healing coating was analyzed in following.It depicted the guiding effect of biomimetic structure and the shield function of self-healing coating,resulting in anticorrosion and wear resistance of subsoiler.
基金supported by the National Natural Science Foundation of China (21301005)the Natural Science Foundation of Anhui Province (1408085QB31)the open fund of Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control (KFK201508)
文摘Metal-organic frameworks(MOFs) have been emerging as important multifunctional hybrid materials, not only due to the diversify framework architectures, but also contribute to the rich interactions among metals, ligands and guests. Nitro explosives have important influences for environmental protection and national homeland security. In this review, a brief description of luminescent MOFs is presented, accompanied by a short comment on the four types of metal-based luminescent MOFs as sensing materials for nitro explosives detection. Then the trends and challenges of luminescent MOFs as sensing materials for nitro explosives are also prospected.
基金supported by Shanghai Science and Technology Commission Research Project(21ZR1438900)the Incubating Program for Clinical Research and Innovation of Renji Hospital(PYXJS16-008,PYIII20-07).
文摘Dear editor,The prognosis of metastatic renal cell carcinoma(mRCC)has been significantly improvedwith the development and widespread use of vascular endothelial growth factor(VEGF)pathway inhibitors and mammalian target of rapamycin(mTOR)pathway inhibitors[1].For the past decade,the standard of care utilized in the first-line setting was VEGF-targeted therapies.Recently,the mRCC treatment landscape has rapidly changed with the exploration of combinations of immune checkpoint inhibitors(ICIs)and anti-VEGF agents[2,3].
