AIM To compare the tolerability and quality of bowel cleansing between 2 L polyethylene glycol(PEG)and reduced-dose sodium phosphate(Na P)tablets as a preparation for colonoscopy.METHODS Two hundred patients were rand...AIM To compare the tolerability and quality of bowel cleansing between 2 L polyethylene glycol(PEG)and reduced-dose sodium phosphate(Na P)tablets as a preparation for colonoscopy.METHODS Two hundred patients were randomly assigned to the PEG or Na P groups at the same ratio.The Na P group patients took 30 tablets with 2 L of clear liquid,while the PEG group patients took 2L of PEG.Tolerability was assessed by a questionnaire about taste,volume,and the overall impression.The bowel cleansing quality was evaluated by colonoscopists.RESULTS Although Na P showed better tolerability in terms of taste,volume and overall impression(P<0.01,P<0.01 and P=0.02,respectively),the overall cleansing quality was better in the PEG group(P<0.01).A subgroup analysis,stratified by sex and age,indicated that Na P was associated with better tolerability and equivalent bowel cleansing quality in females of<50years of age.CONCLUSION Despite the better tolerability,the use of 30 Na P tablets with 2 L of clear liquid should be limited due to its lower cleansing quality;however,in certain cases the regimen may deserve consideration,particularly in cases involving young women.展开更多
文摘AIM To compare the tolerability and quality of bowel cleansing between 2 L polyethylene glycol(PEG)and reduced-dose sodium phosphate(Na P)tablets as a preparation for colonoscopy.METHODS Two hundred patients were randomly assigned to the PEG or Na P groups at the same ratio.The Na P group patients took 30 tablets with 2 L of clear liquid,while the PEG group patients took 2L of PEG.Tolerability was assessed by a questionnaire about taste,volume,and the overall impression.The bowel cleansing quality was evaluated by colonoscopists.RESULTS Although Na P showed better tolerability in terms of taste,volume and overall impression(P<0.01,P<0.01 and P=0.02,respectively),the overall cleansing quality was better in the PEG group(P<0.01).A subgroup analysis,stratified by sex and age,indicated that Na P was associated with better tolerability and equivalent bowel cleansing quality in females of<50years of age.CONCLUSION Despite the better tolerability,the use of 30 Na P tablets with 2 L of clear liquid should be limited due to its lower cleansing quality;however,in certain cases the regimen may deserve consideration,particularly in cases involving young women.