<i><span style="font-family:Verdana;">Helicobacter pylori</span></i><span style="font-family:Verdana;"> infection is a major public health problem globally, with high ...<i><span style="font-family:Verdana;">Helicobacter pylori</span></i><span style="font-family:Verdana;"> infection is a major public health problem globally, with high prevalence in developing countries associated with poor sanitation, low standard of living, urban-rural disparity and increased gastrointestinal pathologies. This preliminary study determine</span><span style="font-family:Verdana;">d</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> the seroprevalence of </span><i><span style="font-family:Verdana;">H.</span></i></span><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">pylori</span></i><span style="font-family:;" "=""><span style="font-family:Verdana;"> infection among asymptomatic rural population and association of sociodemographic variables on the result outcome. A total of 250 asymptomatic volunteered participants were screened for </span><i><span style="font-family:Verdana;">H.</span></i></span><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">pylori</span></i><span style="font-family:Verdana;"> antibodies, using rapid immunochromatographic strips. 44.8%</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(112/250) were seropositive, and showed increased prevalence with the age</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">group, <15</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">years (8.0%), 18</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">39</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">years</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(23.5%) and 40</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">65</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">years</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(12</span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;">0%) with no significant difference. High prevalence among males,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">88</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(35.2) compared to 24</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(9.6) females</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.228). Significant association was observed with marital status, high prevalence among married participants 63</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(25.0) followed by singles,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">41</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(16.4)</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.010). Similarly, significant prevalence </span><span style="font-family:Verdana;">was </span><span style="font-family:Verdana;">observed among participants with non-formal education,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">60</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(24.0) followed by primary education,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">21</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(8.4)</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.51).</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">While non-salary earners accounted for 79</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(31.6)</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">0.244). The </span><i><span style="font-family:Verdana;">H.</span></i></span><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">pylori</span></i><i><span style="font-family:;" "=""> </span></i><span style="font-family:;" "=""><span style="font-family:Verdana;">seropositivity of 44.8% is relatively low in region with previous reports of high prevalence and predisposing risk factors. Further studies are needed to evaluate the effect of environmental and occupational risk factors for better epidemiological understanding of </span><i><span style="font-family:Verdana;">H. pylori</span></i><span style="font-family:Verdana;"> infection and a template for intervention measures.</span></span>展开更多
文摘<i><span style="font-family:Verdana;">Helicobacter pylori</span></i><span style="font-family:Verdana;"> infection is a major public health problem globally, with high prevalence in developing countries associated with poor sanitation, low standard of living, urban-rural disparity and increased gastrointestinal pathologies. This preliminary study determine</span><span style="font-family:Verdana;">d</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> the seroprevalence of </span><i><span style="font-family:Verdana;">H.</span></i></span><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">pylori</span></i><span style="font-family:;" "=""><span style="font-family:Verdana;"> infection among asymptomatic rural population and association of sociodemographic variables on the result outcome. A total of 250 asymptomatic volunteered participants were screened for </span><i><span style="font-family:Verdana;">H.</span></i></span><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">pylori</span></i><span style="font-family:Verdana;"> antibodies, using rapid immunochromatographic strips. 44.8%</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(112/250) were seropositive, and showed increased prevalence with the age</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">group, <15</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">years (8.0%), 18</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">39</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">years</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(23.5%) and 40</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">65</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">years</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(12</span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;">0%) with no significant difference. High prevalence among males,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">88</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(35.2) compared to 24</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(9.6) females</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.228). Significant association was observed with marital status, high prevalence among married participants 63</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(25.0) followed by singles,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">41</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(16.4)</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.010). Similarly, significant prevalence </span><span style="font-family:Verdana;">was </span><span style="font-family:Verdana;">observed among participants with non-formal education,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">60</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(24.0) followed by primary education,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">21</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(8.4)</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.51).</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">While non-salary earners accounted for 79</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(31.6)</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">0.244). The </span><i><span style="font-family:Verdana;">H.</span></i></span><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">pylori</span></i><i><span style="font-family:;" "=""> </span></i><span style="font-family:;" "=""><span style="font-family:Verdana;">seropositivity of 44.8% is relatively low in region with previous reports of high prevalence and predisposing risk factors. Further studies are needed to evaluate the effect of environmental and occupational risk factors for better epidemiological understanding of </span><i><span style="font-family:Verdana;">H. pylori</span></i><span style="font-family:Verdana;"> infection and a template for intervention measures.</span></span>
