目的检索、遴选并整合慢性阻塞性肺疾病患者长期氧疗管理的最佳证据,为临床工作提供参考。方法系统依次检索BMJ best practice、Up To Date、JBI循证卫生保健国际合作中心图书馆、系统摘要数据库、美国国立指南数据库、加拿大安大略注...目的检索、遴选并整合慢性阻塞性肺疾病患者长期氧疗管理的最佳证据,为临床工作提供参考。方法系统依次检索BMJ best practice、Up To Date、JBI循证卫生保健国际合作中心图书馆、系统摘要数据库、美国国立指南数据库、加拿大安大略注册护士协会、苏格兰学院间指南网、国际指南协作组、英国国家卫生与临床优化研究所库、澳大利亚指南网、临床系统改进协会、慢性阻塞性肺疾病全球倡议、美国胸科协会、英国胸科协会、爱尔兰胸科协会、澳大利亚和新西兰胸科协会、医脉通临床指南网、Cochrane Library、EMbase、CINAHL、PubMed、万方数据库、中国知网、维普数据库、中国生物医学文献数据库中所有关于慢性阻塞性肺疾病患者长期氧疗证据,包括指南、专家共识、最佳实践、系统评价、证据总结及随机对照研究。由2名研究员对文献质量独立评价,结合专业人士的判断,对符合纳入标准的文献进行资料提取。结果共纳入20篇文献,包括临床决策2篇、证据总结4篇、指南8篇、系统评价1篇、专家共识3篇、随机对照试验2篇。总结长期氧疗定义、多学科团队、适用指征、氧疗设备基本要求与选择、实施、动态评估与监测、健康教育与出院随访8大类27条最佳证据。结论本研究总结了目前慢性阻塞性肺疾病患者长期氧疗管理的最佳证据,为标准化临床护理方案提供循证依据,改善患者结局,提升护理质量。展开更多
For preparing fluorinated quinolone antibiotic medicine locally used in stomatology, simultaneous determination of norfloxacin, ciprofloxacin, and enoxacin was carried out by multiphase ion chromatography with fluores...For preparing fluorinated quinolone antibiotic medicine locally used in stomatology, simultaneous determination of norfloxacin, ciprofloxacin, and enoxacin was carried out by multiphase ion chromatography with fluorescence detection. Quinolone antibiotics were separated by Dionex OmniPac PAX-500 column with an eluent of 15 mmol/L H2SO4 and 35% methanol (v/v) at a flow-rate of 1.0 ml/min and detected with fluorescence with excitation and emission wave lengths of 347 nm and 420 nm respectively. The detection limits (S/N=3) of norfloxacin, ciprofloxacin and enoxacin were 50, 105 and 80 ng/ml respectively. The relative standard deviations of retention time, peak area and peak height were less than 1.1% and good linear relationship resulted. The developed method was applied to pharmaceutical formulations and biological fluids.展开更多
文摘目的检索、遴选并整合慢性阻塞性肺疾病患者长期氧疗管理的最佳证据,为临床工作提供参考。方法系统依次检索BMJ best practice、Up To Date、JBI循证卫生保健国际合作中心图书馆、系统摘要数据库、美国国立指南数据库、加拿大安大略注册护士协会、苏格兰学院间指南网、国际指南协作组、英国国家卫生与临床优化研究所库、澳大利亚指南网、临床系统改进协会、慢性阻塞性肺疾病全球倡议、美国胸科协会、英国胸科协会、爱尔兰胸科协会、澳大利亚和新西兰胸科协会、医脉通临床指南网、Cochrane Library、EMbase、CINAHL、PubMed、万方数据库、中国知网、维普数据库、中国生物医学文献数据库中所有关于慢性阻塞性肺疾病患者长期氧疗证据,包括指南、专家共识、最佳实践、系统评价、证据总结及随机对照研究。由2名研究员对文献质量独立评价,结合专业人士的判断,对符合纳入标准的文献进行资料提取。结果共纳入20篇文献,包括临床决策2篇、证据总结4篇、指南8篇、系统评价1篇、专家共识3篇、随机对照试验2篇。总结长期氧疗定义、多学科团队、适用指征、氧疗设备基本要求与选择、实施、动态评估与监测、健康教育与出院随访8大类27条最佳证据。结论本研究总结了目前慢性阻塞性肺疾病患者长期氧疗管理的最佳证据,为标准化临床护理方案提供循证依据,改善患者结局,提升护理质量。
基金Project supported by the National Natural Science Foundation of China (Nos.20375035 and 20527005)the Natural Science Foundation of Zhejiang Province (No.Z404105), China
文摘For preparing fluorinated quinolone antibiotic medicine locally used in stomatology, simultaneous determination of norfloxacin, ciprofloxacin, and enoxacin was carried out by multiphase ion chromatography with fluorescence detection. Quinolone antibiotics were separated by Dionex OmniPac PAX-500 column with an eluent of 15 mmol/L H2SO4 and 35% methanol (v/v) at a flow-rate of 1.0 ml/min and detected with fluorescence with excitation and emission wave lengths of 347 nm and 420 nm respectively. The detection limits (S/N=3) of norfloxacin, ciprofloxacin and enoxacin were 50, 105 and 80 ng/ml respectively. The relative standard deviations of retention time, peak area and peak height were less than 1.1% and good linear relationship resulted. The developed method was applied to pharmaceutical formulations and biological fluids.
