AIM: To evaluate the 5-year survival after laparoscopic surgery vs open surgery for stages Ⅱ and Ⅲ rectal cancer.METHODS:This study enrolled 406 consecutive patients who underwent curative resection for stagesⅡand...AIM: To evaluate the 5-year survival after laparoscopic surgery vs open surgery for stages Ⅱ and Ⅲ rectal cancer.METHODS:This study enrolled 406 consecutive patients who underwent curative resection for stagesⅡandⅢrectal cancer between January 2000 and December 2009[laparoscopic rectal resection(LRR),n=152;open rectal resection(ORR),n=254].Clinical characteristics,operative outcomes,pathological outcomes,postoperative recovery,and 5-year survival outcomes were compared between the two groups.RESULTS:Most of the clinical characteristics were similar except age(59 years vs 55 years,P=0.033)between the LRR group and ORR group.The proportion of anterior resection was higher in the LRR group than that in the ORR group(81.6%vs 66.1%,P=0.001).The LRR group had less estimated blood loss(50m L vs 200 m L,P<0.001)and a lower rate of blood transfusion(4.6%vs 11.8%,P=0.019)compared to the ORR group.The pathological outcomes of the two groups were comparable.The LRR group was associated with faster recovery of bowel function(2.8 d vs 3.7 d,P<0.001)and shorter postoperative hospital stay(11.7 d vs 13.7 d,P<0.001).The median followup time was 63 mo in the LRR group and 65 mo in the ORR group.As for the survival outcomes,the 5-year local recurrence rate(16.0%vs 16.4%,P=0.753),5-year disease-free survival(DFS)rate(63.0%vs63.1%,P=0.589),and 5-year overall survival(OS)rate(68.1%vs 63.5%,P=0.682)were comparable between the LRR group and the ORR group.Stageby stage,there were also no statistical differences between the LRR group and the ORR group in terms of the 5-year local recurrence rate(stageⅡ:6.3%vs 8.7%,P=0.623;stageⅢ:26.4%vs 23.2%,P=0.747),5-year DFS rate(stageⅡ:77.5%vs 77.6%,P=0.462;stageⅢ:46.5%vs 50.9%,P=0.738),and5-year OS rate(stageⅡ:81.4%vs 74.3%,P=0.242;stageⅢ:53.9%vs 54.1%,P=0.459).CONCLUSION:LRR for stagesⅡandⅢrectal cancer can yield comparable long-term survival while achieving short-term benefits compared to open surgery.展开更多
Objective: To study the clinical therapy and prognosis in children with transient congenital hypothyroidism (CH). Methods: Fifty-seven children with CH diagnosed after neonatal screening were treated with low-dosa...Objective: To study the clinical therapy and prognosis in children with transient congenital hypothyroidism (CH). Methods: Fifty-seven children with CH diagnosed after neonatal screening were treated with low-dosage levothyroxine (L-T4). Follow-up evaluation included the determination of TT3, TT4 and TSH serum levels and the assessment of thyroid gland morphology, bone age, growth development and development quotients (DQ). A full check-up was performed at age 2, when the affected children first discontinued the L-T4 treatment for 1 month, and one year later. Development quotients were compared with a control group of 29 healthy peers. Results: The initial L-T4 dosage administered was 3.21-5.81μg/(kg·d) with an average of (16.25±3.87)μg/d. Mean duration of therapy was (28.09±9.56) months. No significant difference was found between study group and control group in the DQ test (average score (106.58±14.40) vs (102.4±8.6), P〉0.05) and 96.49% of the CH children achieved a test score above 85. Bone age, 99mTc scans and ultrasonographic findings were all normal, and evaluation of physical development was normal too, as were the serum levels of TT3, TT4 and TSH after one year of follow-up. Conclusion: AL-T4 dosage of 3.21-5.81μg/(kg·d) was found sufficient for the treatment of transient CH. The treated children showed satisfactory overall mental and physical development at age 2. So it is possible for CH children to stop taking medicine if their laboratory findings and physical development are all normal after regular treatment and 2-3 years of follow-up.展开更多
High strength Al Zn Mg Cu alloys were produced by spray forming process, and compacted by hot extrusion. The results show that the as deposited billets have fine grained microstructure and low porosity. After heat tre...High strength Al Zn Mg Cu alloys were produced by spray forming process, and compacted by hot extrusion. The results show that the as deposited billets have fine grained microstructure and low porosity. After heat treatment, mechanical properties increase greatly: tensile strength up to 754 MPa, yield strength up to 722 MPa, fracture elongation up to 8%, and elastic modulus up to 72 GPa, respectively. [展开更多
The large-diameter cylinder structure, which is made of large successive bottomless cylinders placed on foundation bed or partly driven into soil, is a recently developed retaining structure in China. It can be used i...The large-diameter cylinder structure, which is made of large successive bottomless cylinders placed on foundation bed or partly driven into soil, is a recently developed retaining structure in China. It can be used in port, coastal and offshore works. The method for stability analysis of the large-diameter cylinder structure, especially for stability analysis of the embedded large-diameter cylinder structure, is an important issue. In this paper, an idea is presented that is, embedded large-diameter cylinder quays can be divided into two types, i.e. the gravity wall type and the cylinder pile wall type. A method for stability analysis of the large-diameter cylinder quay of the cylinder pile wall type is developed and a method for stability analysis of the large-diameter cylinder quay of the gravity wall type is also proposed. The effect of significant parameters on the stability of the large-diameter cylinder quay of the cylinder pile wall type is investigated through numerical calculation.展开更多
Overmany alarms of modern chemical process give the operators many difficulties to decision and diag- nosis. In order to ensure safe production and process operating, management and optimization of alarm information a...Overmany alarms of modern chemical process give the operators many difficulties to decision and diag- nosis. In order to ensure safe production and process operating, management and optimization of alarm information are challenge work that must be confronted. A new process alarm management method based on fuzzy clustering- ranking algorithm is proposed. The fuzzy clustering algorithm is used to cluster rationally the process variables, and difference driving decision algorithm ranks different clusters and process parameters in every cluster. The alarm signal of higher rank is handled preferentially to manage effectively alarms and avoid blind operation. The validity of proposed algorithm and solution is verified by the practical application of ethylene cracking furnace system. It is an effective and dependable alarm management method to improve operating safety in industrial process.展开更多
Near-fault strong ground motions that resulted in serious structural damage are characterized by directivity effect and pulse-type motion. Large-amplitude and long-period pulses are contained in the velocity time-his...Near-fault strong ground motions that resulted in serious structural damage are characterized by directivity effect and pulse-type motion. Large-amplitude and long-period pulses are contained in the velocity time-history traces of near-fault pulse-type records. A reasonable model of equivalent velocity pulse is proposed on the basis of the ex- isted models in this paper to simplify the calculation and analysis. Based on the large amount of collected near-fault strong earthquakes records, the parameters describing equivalent velocity pulse model such as pulse period, pulse intensity and number of predominant pulses are studied, and comparison is made with the results obtained by others models. The proposed model is contributive to the seismic design for structures in near-fault areas.展开更多
The principle of a CAD method of converting the pre-designed figures in image form into complex dobby weaves with the appearances similar to the original figures is mainly introduced in this paper. A few designed weav...The principle of a CAD method of converting the pre-designed figures in image form into complex dobby weaves with the appearances similar to the original figures is mainly introduced in this paper. A few designed weaves by the created CAD system are also given as examples of the practical application in the area of complex dobby weave designing.展开更多
Dipyrido [3, 2-a:2,3-c] phenazine moiety has been introduced as neutral ligand in europium complex. Therefore, a new europium complex with saturated emission, strong fluorescent intensity and good solubility was desi...Dipyrido [3, 2-a:2,3-c] phenazine moiety has been introduced as neutral ligand in europium complex. Therefore, a new europium complex with saturated emission, strong fluorescent intensity and good solubility was designed and synthesized for the first time. Its photoluminescence and UV properties were examined. The experimental results showed that this new Eu-complex could be used as red electroluminescent materials.展开更多
A kW-scale molten carbonate fuel cells stack was developed and 800-hours’ operating test and performance experimental research had been done. Utilizing domestic materials completely, we developed NiO cathode and Ni-A...A kW-scale molten carbonate fuel cells stack was developed and 800-hours’ operating test and performance experimental research had been done. Utilizing domestic materials completely, we developed NiO cathode and Ni-Al anode with the active area of 336cm 2 and Υ-LiAlO 2 electrolyte tile and bipolar plate with the area of 900cm 2. The stack was composed of thirty cells, with 62%Li 2CO 3+38%K 2CO 3 as its electrolyte. During the 800 hours’ continuous operating, the performance of the stack was stable. With 99.7%(mole fraction) H 2 as fuel and O 2 from air as oxidant, the average operating voltage of a cell was about 0.72 V. The maximal current density attained to 165mA/cm 2, and the maximal output power attained to 1080 Watt. The whole performance of the stack approached to the international level in the early 90’s. This paper gives the main works and experiments results.展开更多
基金Supported by National Key Clinical Specialty Construction Project of China,the National High Technology Research and Development Program of China No.2012AA021103the Research Fund of Public Welfare in Health Industry,National Health and Family Planning Commission of China,No.201502039
文摘AIM: To evaluate the 5-year survival after laparoscopic surgery vs open surgery for stages Ⅱ and Ⅲ rectal cancer.METHODS:This study enrolled 406 consecutive patients who underwent curative resection for stagesⅡandⅢrectal cancer between January 2000 and December 2009[laparoscopic rectal resection(LRR),n=152;open rectal resection(ORR),n=254].Clinical characteristics,operative outcomes,pathological outcomes,postoperative recovery,and 5-year survival outcomes were compared between the two groups.RESULTS:Most of the clinical characteristics were similar except age(59 years vs 55 years,P=0.033)between the LRR group and ORR group.The proportion of anterior resection was higher in the LRR group than that in the ORR group(81.6%vs 66.1%,P=0.001).The LRR group had less estimated blood loss(50m L vs 200 m L,P<0.001)and a lower rate of blood transfusion(4.6%vs 11.8%,P=0.019)compared to the ORR group.The pathological outcomes of the two groups were comparable.The LRR group was associated with faster recovery of bowel function(2.8 d vs 3.7 d,P<0.001)and shorter postoperative hospital stay(11.7 d vs 13.7 d,P<0.001).The median followup time was 63 mo in the LRR group and 65 mo in the ORR group.As for the survival outcomes,the 5-year local recurrence rate(16.0%vs 16.4%,P=0.753),5-year disease-free survival(DFS)rate(63.0%vs63.1%,P=0.589),and 5-year overall survival(OS)rate(68.1%vs 63.5%,P=0.682)were comparable between the LRR group and the ORR group.Stageby stage,there were also no statistical differences between the LRR group and the ORR group in terms of the 5-year local recurrence rate(stageⅡ:6.3%vs 8.7%,P=0.623;stageⅢ:26.4%vs 23.2%,P=0.747),5-year DFS rate(stageⅡ:77.5%vs 77.6%,P=0.462;stageⅢ:46.5%vs 50.9%,P=0.738),and5-year OS rate(stageⅡ:81.4%vs 74.3%,P=0.242;stageⅢ:53.9%vs 54.1%,P=0.459).CONCLUSION:LRR for stagesⅡandⅢrectal cancer can yield comparable long-term survival while achieving short-term benefits compared to open surgery.
文摘Objective: To study the clinical therapy and prognosis in children with transient congenital hypothyroidism (CH). Methods: Fifty-seven children with CH diagnosed after neonatal screening were treated with low-dosage levothyroxine (L-T4). Follow-up evaluation included the determination of TT3, TT4 and TSH serum levels and the assessment of thyroid gland morphology, bone age, growth development and development quotients (DQ). A full check-up was performed at age 2, when the affected children first discontinued the L-T4 treatment for 1 month, and one year later. Development quotients were compared with a control group of 29 healthy peers. Results: The initial L-T4 dosage administered was 3.21-5.81μg/(kg·d) with an average of (16.25±3.87)μg/d. Mean duration of therapy was (28.09±9.56) months. No significant difference was found between study group and control group in the DQ test (average score (106.58±14.40) vs (102.4±8.6), P〉0.05) and 96.49% of the CH children achieved a test score above 85. Bone age, 99mTc scans and ultrasonographic findings were all normal, and evaluation of physical development was normal too, as were the serum levels of TT3, TT4 and TSH after one year of follow-up. Conclusion: AL-T4 dosage of 3.21-5.81μg/(kg·d) was found sufficient for the treatment of transient CH. The treated children showed satisfactory overall mental and physical development at age 2. So it is possible for CH children to stop taking medicine if their laboratory findings and physical development are all normal after regular treatment and 2-3 years of follow-up.
文摘High strength Al Zn Mg Cu alloys were produced by spray forming process, and compacted by hot extrusion. The results show that the as deposited billets have fine grained microstructure and low porosity. After heat treatment, mechanical properties increase greatly: tensile strength up to 754 MPa, yield strength up to 722 MPa, fracture elongation up to 8%, and elastic modulus up to 72 GPa, respectively. [
基金by the National Natural Science Foundation of China(Grant No.59679003)the Natural Science Foundation of Tianjin(Grant No.973606311)
文摘The large-diameter cylinder structure, which is made of large successive bottomless cylinders placed on foundation bed or partly driven into soil, is a recently developed retaining structure in China. It can be used in port, coastal and offshore works. The method for stability analysis of the large-diameter cylinder structure, especially for stability analysis of the embedded large-diameter cylinder structure, is an important issue. In this paper, an idea is presented that is, embedded large-diameter cylinder quays can be divided into two types, i.e. the gravity wall type and the cylinder pile wall type. A method for stability analysis of the large-diameter cylinder quay of the cylinder pile wall type is developed and a method for stability analysis of the large-diameter cylinder quay of the gravity wall type is also proposed. The effect of significant parameters on the stability of the large-diameter cylinder quay of the cylinder pile wall type is investigated through numerical calculation.
基金Partially supported by the National Natural Science Foundation of China (No. 29976003), the Key Research Project ofScience and Technology from Ministry of Education in China (No. 01024), and Sinopec Science & Technology DevelopmentProject (No. E03007)
文摘Overmany alarms of modern chemical process give the operators many difficulties to decision and diag- nosis. In order to ensure safe production and process operating, management and optimization of alarm information are challenge work that must be confronted. A new process alarm management method based on fuzzy clustering- ranking algorithm is proposed. The fuzzy clustering algorithm is used to cluster rationally the process variables, and difference driving decision algorithm ranks different clusters and process parameters in every cluster. The alarm signal of higher rank is handled preferentially to manage effectively alarms and avoid blind operation. The validity of proposed algorithm and solution is verified by the practical application of ethylene cracking furnace system. It is an effective and dependable alarm management method to improve operating safety in industrial process.
基金National Natural Science Foundation of China (50278002).
文摘Near-fault strong ground motions that resulted in serious structural damage are characterized by directivity effect and pulse-type motion. Large-amplitude and long-period pulses are contained in the velocity time-history traces of near-fault pulse-type records. A reasonable model of equivalent velocity pulse is proposed on the basis of the ex- isted models in this paper to simplify the calculation and analysis. Based on the large amount of collected near-fault strong earthquakes records, the parameters describing equivalent velocity pulse model such as pulse period, pulse intensity and number of predominant pulses are studied, and comparison is made with the results obtained by others models. The proposed model is contributive to the seismic design for structures in near-fault areas.
文摘The principle of a CAD method of converting the pre-designed figures in image form into complex dobby weaves with the appearances similar to the original figures is mainly introduced in this paper. A few designed weaves by the created CAD system are also given as examples of the practical application in the area of complex dobby weave designing.
基金This work was supported by the National Natural Science Foundation of China (No29992530-6) and Provincial Natural Science Foundation of Hunan (00JJY2043).
文摘Dipyrido [3, 2-a:2,3-c] phenazine moiety has been introduced as neutral ligand in europium complex. Therefore, a new europium complex with saturated emission, strong fluorescent intensity and good solubility was designed and synthesized for the first time. Its photoluminescence and UV properties were examined. The experimental results showed that this new Eu-complex could be used as red electroluminescent materials.
基金ShanghaiScienceandTechnologyDevelopmentFunds (No .9930 12 0 13),andtheNational985ScientificProjectDevelopmentFundsandpartoffundsupportofShanghaiElectricalGroups
文摘A kW-scale molten carbonate fuel cells stack was developed and 800-hours’ operating test and performance experimental research had been done. Utilizing domestic materials completely, we developed NiO cathode and Ni-Al anode with the active area of 336cm 2 and Υ-LiAlO 2 electrolyte tile and bipolar plate with the area of 900cm 2. The stack was composed of thirty cells, with 62%Li 2CO 3+38%K 2CO 3 as its electrolyte. During the 800 hours’ continuous operating, the performance of the stack was stable. With 99.7%(mole fraction) H 2 as fuel and O 2 from air as oxidant, the average operating voltage of a cell was about 0.72 V. The maximal current density attained to 165mA/cm 2, and the maximal output power attained to 1080 Watt. The whole performance of the stack approached to the international level in the early 90’s. This paper gives the main works and experiments results.