期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
Finite Difference-Peridynamic Differential Operator for Solving Transient Heat Conduction Problems
1
作者 Chunlei Ruan Cengceng Dong +2 位作者 zeyue zhang Boyu Chen Zhijun Liu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第9期2707-2728,共22页
Transient heat conduction problems widely exist in engineering.In previous work on the peridynamic differential operator(PDDO)method for solving such problems,both time and spatial derivatives were discretized using t... Transient heat conduction problems widely exist in engineering.In previous work on the peridynamic differential operator(PDDO)method for solving such problems,both time and spatial derivatives were discretized using the PDDO method,resulting in increased complexity and programming difficulty.In this work,the forward difference formula,the backward difference formula,and the centered difference formula are used to discretize the time derivative,while the PDDO method is used to discretize the spatial derivative.Three new schemes for solving transient heat conduction equations have been developed,namely,the forward-in-time and PDDO in space(FT-PDDO)scheme,the backward-in-time and PDDO in space(BT-PDDO)scheme,and the central-in-time and PDDO in space(CT-PDDO)scheme.The stability and convergence of these schemes are analyzed using the Fourier method and Taylor’s theorem.Results show that the FT-PDDO scheme is conditionally stable,whereas the BT-PDDO and CT-PDDO schemes are unconditionally stable.The stability conditions for the FT-PDDO scheme are less stringent than those of the explicit finite element method and explicit finite difference method.The convergence rate in space for these three methods is two.These constructed schemes are applied to solve one-dimensional and two-dimensional transient heat conduction problems.The accuracy and validity of the schemes are verified by comparison with analytical solutions. 展开更多
关键词 Peridynamic differential operator finite difference method STABILITY transient heat conduction problem
下载PDF
结直肠肿瘤早诊筛查新策略:基于液体活检技术的筛查方案
2
作者 刘骞 崔巍 +6 位作者 高亦博 张泽跃 李典格 王治杰 王洁 赫捷 中国结直肠癌筛查与早诊早治指南制定专家组 《中华结直肠疾病电子杂志》 2023年第1期17-20,共4页
结直肠肿瘤是我国最常见的恶性肿瘤之一,严重危害国民身体健康。通过简单有效的检测方法对目标人群进行筛查,早期诊断结直肠肿瘤,是降低其危害的有效策略。然而,尽管我国结直肠癌筛查取得了较大进展,但仍存在筛查方法敏感度和特异度不足... 结直肠肿瘤是我国最常见的恶性肿瘤之一,严重危害国民身体健康。通过简单有效的检测方法对目标人群进行筛查,早期诊断结直肠肿瘤,是降低其危害的有效策略。然而,尽管我国结直肠癌筛查取得了较大进展,但仍存在筛查方法敏感度和特异度不足,接受度和依从性较差等问题,影响了筛查效果。液体活检作为近些年来新兴的检测技术,其内涵丰富,可选择的检测靶点多,同时具有取样方便,创伤小,人群接受度高,易于推广和开展的优点,在结直肠肿瘤筛查早诊工作中具有广阔的应用前景。血液ctDNA可提供患者体内肿瘤的全景数据,在早期肿瘤患者体内含量较高,是结直肠肿瘤早诊筛查的重要靶点。 展开更多
关键词 结直肠肿瘤 筛查 液体活检 CTDNA
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部