目的探讨绝经后女性骨密度与血清维生素K1水平之间的相关性。方法使用标准化的酶联免疫吸附试验(ELISA)试剂盒测量46例绝经后骨质疏松女性和30名绝经后健康对照女性的血清维生素K1水平。检测腰椎(1～4)的骨密度(bone mineral density, B...目的探讨绝经后女性骨密度与血清维生素K1水平之间的相关性。方法使用标准化的酶联免疫吸附试验(ELISA)试剂盒测量46例绝经后骨质疏松女性和30名绝经后健康对照女性的血清维生素K1水平。检测腰椎(1～4)的骨密度(bone mineral density, BMD)。结果绝经后骨质疏松女性组血清维生素K1水平明显低于正常对照组(P<0.05),绝经后骨质疏松女性血清维生素K1浓度与腰椎BMD呈正相关(R=0.545,P=0.003);绝经后正常对照组血清维生素K1浓度与腰椎BMD呈正相关(R=0.513,P=0.009)。维生素K1对骨质疏松症的诊断敏感性和特异性分别为91%和98%(截止值:0.853 ng/mL);维生素K1的ROC曲线下面积(AUC)为0.985,奇数比为18.88。结论维生素K1与诊断绝经后骨质疏松症呈负相关。展开更多
Lanthanum-doped muscovite(MC) composite particles(hereinafter abbreviated as La-MC) were prepared by the mechanical solid-state-chemistry-reaction method, followed by surface modification with oleic acid. The microstr...Lanthanum-doped muscovite(MC) composite particles(hereinafter abbreviated as La-MC) were prepared by the mechanical solid-state-chemistry-reaction method, followed by surface modification with oleic acid. The microstructure of materials was characterized by SEM, XRD, EDS and FTIR. Furthermore, the friction-reduction and anti-wear properties of MC and La-MC as lubricant additives in lithium grease were evaluated using a four-ball friction and wear tester. The results showed that La(OH)_3 nanoparticles were coated on the surface of muscovite. Both MC and La-MC can effectively improve the friction-reduction and anti-wear properties of lithium grease and La-MC presents better tribological properties than MC. The excellent tribological properties of La-MC can be attributed to the formation of the adsorbed La-MC film and the chemical reaction film mainly composed of Fe_2O_3 and SiO_2 on the worn surface, as well as the catalysis of lanthanum element during the friction process.展开更多
文摘目的探讨绝经后女性骨密度与血清维生素K1水平之间的相关性。方法使用标准化的酶联免疫吸附试验(ELISA)试剂盒测量46例绝经后骨质疏松女性和30名绝经后健康对照女性的血清维生素K1水平。检测腰椎(1～4)的骨密度(bone mineral density, BMD)。结果绝经后骨质疏松女性组血清维生素K1水平明显低于正常对照组(P<0.05),绝经后骨质疏松女性血清维生素K1浓度与腰椎BMD呈正相关(R=0.545,P=0.003);绝经后正常对照组血清维生素K1浓度与腰椎BMD呈正相关(R=0.513,P=0.009)。维生素K1对骨质疏松症的诊断敏感性和特异性分别为91%和98%(截止值:0.853 ng/mL);维生素K1的ROC曲线下面积(AUC)为0.985,奇数比为18.88。结论维生素K1与诊断绝经后骨质疏松症呈负相关。
基金supported by the Postdoctoral Science Foundation of China(XM2013018)Logistics Project Foundation of China(Oil 20070209)
文摘Lanthanum-doped muscovite(MC) composite particles(hereinafter abbreviated as La-MC) were prepared by the mechanical solid-state-chemistry-reaction method, followed by surface modification with oleic acid. The microstructure of materials was characterized by SEM, XRD, EDS and FTIR. Furthermore, the friction-reduction and anti-wear properties of MC and La-MC as lubricant additives in lithium grease were evaluated using a four-ball friction and wear tester. The results showed that La(OH)_3 nanoparticles were coated on the surface of muscovite. Both MC and La-MC can effectively improve the friction-reduction and anti-wear properties of lithium grease and La-MC presents better tribological properties than MC. The excellent tribological properties of La-MC can be attributed to the formation of the adsorbed La-MC film and the chemical reaction film mainly composed of Fe_2O_3 and SiO_2 on the worn surface, as well as the catalysis of lanthanum element during the friction process.
