Based on the intersection of“Implementing the National Strategy to Actively Cope with Population Aging”and“Guiding Opinions on Future Rural Construction”in Zhejiang Province,this study constructed the evaluation i...Based on the intersection of“Implementing the National Strategy to Actively Cope with Population Aging”and“Guiding Opinions on Future Rural Construction”in Zhejiang Province,this study constructed the evaluation index system of rural age-appropriate building space.This is done by analyzing the current situation locally and internationally,summarizing the existing problems,and optimizing countermeasures.The cross-analysis method is adopted by fully listening to the opinions of the elderly and introducing a professional team to transform the physical,psychological,and rural natural environment of the elderly.The renovation strategies of building layout,indoor and outdoor space,and supporting facilities for the elderly are put forward.Looking to the future,including the application of intelligent technology,the development of a community pension model,and multi-party cooperation,it aims to create a comfortable,safe,and convenient living environment for rural elderly people,improve the quality of life,promote rural revitalization and actively respond to the challenges of population aging.展开更多
Milk allergy is one of the most common food allergies,affecting 6%of young children,andβ-lactoglobulin(β-LG)is the main milk allergen.Clostridium tyrobutyricum Z816 was selected for the degradation ofβ-LG,which was...Milk allergy is one of the most common food allergies,affecting 6%of young children,andβ-lactoglobulin(β-LG)is the main milk allergen.Clostridium tyrobutyricum Z816 was selected for the degradation ofβ-LG,which was successfully reduced by about 90%using permeabilized bacteria under the optimized conditions.The hydrolyzed peptides were identified by liquid chromatography-tandem mass spectrometry(LC-MS/MS)and analyzed by molecular modeling,which indicated that C.tyrobutyricum Z816 could effectively degrade the antigenic epitopes ofβ-LG.Finally,the concentration and digestibility ofβ-LG in actual samples was quantified using enzyme-linked immunosorbent assay(ELISA)and gastrointestinal digestion simulation experiments.The results showed more than 92%ofβ-LG in actual samples was hydrolyzed,and the gastric and total digestibility of whey protein isolate(WPI)was improved by 85.96%and 64.51%,respectively.Therefore,C.tyrobutyricum Z816 offers an effective method to degradeβ-LG and reduce the occurrence of milk allergies,which has great significance for the development of hypoallergenic dairy products.展开更多
基金Study on the aging evaluation of future rural architectural space from the perspective of rural revitalization under the general topic Y202250584 of Zhejiang Provincial Department of Education Zhejiang University Students Science and Technology Innovation Activity Program(New Talent Program)(Project No.2024R449A002)“Research on the Aging Evaluation System of Building Space in the Future Countryside-Xiaoshan District of Hangzhou City as an Example”。
文摘Based on the intersection of“Implementing the National Strategy to Actively Cope with Population Aging”and“Guiding Opinions on Future Rural Construction”in Zhejiang Province,this study constructed the evaluation index system of rural age-appropriate building space.This is done by analyzing the current situation locally and internationally,summarizing the existing problems,and optimizing countermeasures.The cross-analysis method is adopted by fully listening to the opinions of the elderly and introducing a professional team to transform the physical,psychological,and rural natural environment of the elderly.The renovation strategies of building layout,indoor and outdoor space,and supporting facilities for the elderly are put forward.Looking to the future,including the application of intelligent technology,the development of a community pension model,and multi-party cooperation,it aims to create a comfortable,safe,and convenient living environment for rural elderly people,improve the quality of life,promote rural revitalization and actively respond to the challenges of population aging.
基金supported by the National Key R&D Program of China(2017YFC1600404)the National Natural Science Foundation of China(31922070,22008114)the Natural Science Foundation of Jiangsu Province(BK20180038,BK20200684)。
文摘Milk allergy is one of the most common food allergies,affecting 6%of young children,andβ-lactoglobulin(β-LG)is the main milk allergen.Clostridium tyrobutyricum Z816 was selected for the degradation ofβ-LG,which was successfully reduced by about 90%using permeabilized bacteria under the optimized conditions.The hydrolyzed peptides were identified by liquid chromatography-tandem mass spectrometry(LC-MS/MS)and analyzed by molecular modeling,which indicated that C.tyrobutyricum Z816 could effectively degrade the antigenic epitopes ofβ-LG.Finally,the concentration and digestibility ofβ-LG in actual samples was quantified using enzyme-linked immunosorbent assay(ELISA)and gastrointestinal digestion simulation experiments.The results showed more than 92%ofβ-LG in actual samples was hydrolyzed,and the gastric and total digestibility of whey protein isolate(WPI)was improved by 85.96%and 64.51%,respectively.Therefore,C.tyrobutyricum Z816 offers an effective method to degradeβ-LG and reduce the occurrence of milk allergies,which has great significance for the development of hypoallergenic dairy products.
