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Relationship between red blood cell distribution width levels and atrial fibrillation in hypertensive patients 被引量:7
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作者 Li-hui ZHENG Shang-Yu LIU +4 位作者 Feng hu zhi-cheng hu Li-Shui SHEN Ling-Min WU Yan YAO 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2020年第8期486-494,共9页
Background Information on the relationship between red blood cell distribution width(RDW)and atrial fibrillation(AF)in patients with essential hypertension are scarce.The study aimed to assess the relationship between... Background Information on the relationship between red blood cell distribution width(RDW)and atrial fibrillation(AF)in patients with essential hypertension are scarce.The study aimed to assess the relationship between AF and RDW in hypertensive patients.Methods We enrolled 432 hypertensive patients,including 350 AF patients and 82 patients as controls.Patients'demographic,clinical,laboratory and echocardiographic characteristics were recorded.The AF patients were further divided into the persistent and paroxysmal AF subgroups.Electrocardiograms were monitored to identify the cardiac rhythm during blood sampling,and based on the rhythm,the paroxysmal AF group was categorized into the presence(with AF rhythm during blood sampling)and absence(with sinus rhythm during blood sampling)groups.Results The AF group had elevated RDW levels than the controls(12.7%±0.8%vs.12.4%±0.7%,P=0.002),and the persistent AF subgroup had higher RDW levels than the paroxysmal AF subgroup(12.9%±0.8%vs.12.6%±0.8%,P=0.007).Furthermore,in the paroxysmal AF group,the presence group had higher RDW levels than the absence group(13.0%±0.6%vs.12.5%±0.9%,P=0.001).There was no significant difference in RDW levels between the persistent AF subgroup and presence group of the paroxysmal AF subgroup(P=0.533)and between the absence group of the paroxysmal AF subgroup and control group(P=0.262).In multivariate regression analysis,in hypertensive patients,the presence of AF rhythm is an independent predictor for increased RDW concentration(P=0.001).Conclusions The RDW may be associated with the presence of AF rhythm,which implies the importance of maintaining the sinus rhythm in hypertensive patients. 展开更多
关键词 Atrial fibrillation HYPERTENSION INFLAMMATION Red blood cell distribution width
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Ablation strategies for arrhythmogenic right ventricular cardiomyopathy: a systematic review and meta-analysis 被引量:3
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作者 Li-Shui SHEN Li-Min LIU +6 位作者 Li-hui ZHENG Feng hu zhi-cheng hu Shang-Yu LIU Jin-Rui GUO Kush Kumar Bhagat Yan YAO 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2020年第11期694-703,共10页
Background Catheter ablation for ventricular tachycardia(VT) in patients with arrhythmogenic right ventricular cardiomyopathy(ARVC) has significantly evolved over the past decade. However, different ablation strategie... Background Catheter ablation for ventricular tachycardia(VT) in patients with arrhythmogenic right ventricular cardiomyopathy(ARVC) has significantly evolved over the past decade. However, different ablation strategies showed inconsistency in acute and long-term outcomes. Methods We searched the databases of Medline, Embase and Cochrane Library through October 17, 2019 for studies describing the clinical outcomes of VT ablation in ARVC. Data including VT recurrence, all-cause mortality, acute procedural efficacy and major procedural complications were extracted. A meta-analysis with trial sequential analysis was further performed in comparative studies of endo-epicardial versus endocardial-only ablation. Results A total of 24 studies with 717 participants were enrolled. The literatures of epicardial ablation were mainly published after 2010 with total ICD implantation of 73.7%, acute efficacy of 89.8%, major complication of 5.2%, follow-up of 28.9 months, VT freedom of 75.3%, all-cause mortality of 1.1% and heart transplantation of 0.6%. Meta-analysis of 10 comparative studies revealed that compared with endocardial-only approach, epicardial ablation significantly decreased VT recurrence(OR: 0.50;95% CI: 0.30–0.85;P = 0.010), but somehow increased major procedural complications(OR: 4.64;95% CI: 1.28–16.92;P = 0.02), with not evident improvement of acute efficacy(OR: 2.74;95% CI: 0.98–7.65;P = 0.051) or all-cause mortality(OR: 0.87;95% CI: 0.09–8.31;P = 0.90). Conclusion Catheter ablation for VT in ARVC is feasible and effective. Epicardial ablation is associated with better long-term VT freedom, but with more major complications and unremarkable survival or acute efficacy benefit. 展开更多
关键词 Arrhythmogenic right ventricular cardiomyopathy Catheter ablation Ventricular tachycardia
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Perylene Diimide Based Isomeric Conjugated Polymers as Efficient Electron Acceptors for All-polymer Solar Cells 被引量:2
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作者 Xiao-Cheng Liu Qing-Wu Yin +3 位作者 zhi-cheng hu Zhen-Feng Wang Fei huang Yong Cao 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2019年第1期18-27,1-5,共10页
We present here a series of perylene diimide(PDI)based isomeric conjugated polymers for the application as efficient electron acceptors in all-polymer solar cells(all-PSCs).By copolymerizing PDI monomers with 1,4-diet... We present here a series of perylene diimide(PDI)based isomeric conjugated polymers for the application as efficient electron acceptors in all-polymer solar cells(all-PSCs).By copolymerizing PDI monomers with 1,4-diethynylbenzene(para-linkage)and 1,3-diethynylbenzene(meta-linkage),isomeric PDI based conjugated polymers with parallel and non-parallel PDI units inside backbones were obtained.It was found that para-linked conjugated polymer(PA)showed better solubility,strongerπ-πstacking,more favorable blend morphology,and better photovoltaic performance than those of meta-linked conjugated polymers(PM)did.Device based on PTB7-Th:PA(PTB7-Th:poly{4,8-bis[5-(2-ethylhexyl)-thiophen-2-yl]benzo[1,2-b:4,5-b']dithiophene-2,6-diyl-alt-3-fluoro-2-[(2-ethylhexyl)-carbonyl]thieno[3,4-b]thiophene-4,6-diyl})showed significantly enhanced photovoltaic performance than that of PTB7-Th:MA(3.29%versus 0.92%).Moreover,the photovoltaic performance of these polymeric acceptors could be further improved via a terpolymeric strategy.By copolymerizing a small amount of meta-linkages into PA,the optimized terpolymeric acceptors enabled to enhance photovoltaic performance with improved the short-circuit current density(Jsc)and fill factor(FF),resulting in an improved power conversion efficiency(PCE)of 4.03%. 展开更多
关键词 Isomeric CONJUGATED polymers All-polymer solar cells Electron ACCEPTORS PERYLENE DIIMIDE
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Factors influencing adherence to non-vitamin K antagonist oral anticoagulants in the early period after atrial fibrillation catheter ablation in China 被引量:2
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作者 zhi-cheng hu Shang-Yu Liu +5 位作者 Ling-Min Wu Li-Shui Shen Li-Min Liu Guo-Liang Li Li-hui Zheng Yan Yao 《Chinese Medical Journal》 SCIE CAS CSCD 2020年第16期1989-1991,共3页
Anticoagulants are routinely prescribed in the first several weeks after atrial fibrillation(AF)catheter ablation.Nonvitamin K antagonist oral anticoagulants(NOACs)have been recommended over warfarin for their superio... Anticoagulants are routinely prescribed in the first several weeks after atrial fibrillation(AF)catheter ablation.Nonvitamin K antagonist oral anticoagulants(NOACs)have been recommended over warfarin for their superiority.Unlike warfarin need regular clinical visit to perform blood test,NOACs are more patient friendly.But the lack of routine medical contact may lead to poor adherence.Strict adherence to anticoagulant treatment is essential for both efficacy and safety.Considering NOACs are increasingly commonly used in China,it is therefore necessary to evaluate the adherence of NOACs after AF catheter ablation.The purpose of this research was to investigate the treatment adherence and identify factors that could improve the quality of anticoagulation. 展开更多
关键词 VITAMIN ROUTINE FIBRILLATION
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A Near-infrared Non-fullerene Acceptor with Thienopyrrole-expanded Benzo[1,2-b:4,5-b′]dithiophene Core for Polymer Solar Cells 被引量:2
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作者 Zhen Chen Shan-Shan Ma +4 位作者 Kai Zhang zhi-cheng hu Qing-Wu Yin Fei huang Yong Cao 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2021年第1期35-42,I0005,共9页
A near-infrared non-fullerene acceptor(NFA) BDTIC, based on thienopyrrole-expanded benzo[1,2-b:4,5-b′]dithiophene unit(heptacyclic S,N-heteroacene) as core, is designed and synthesized. The aromatic pyrrole ring with... A near-infrared non-fullerene acceptor(NFA) BDTIC, based on thienopyrrole-expanded benzo[1,2-b:4,5-b′]dithiophene unit(heptacyclic S,N-heteroacene) as core, is designed and synthesized. The aromatic pyrrole ring with strong electron-donating ability in the core enhances the intramolecular charge transfer effect, finely tunes the optical bandgap and absorption profile of BDTIC, and thus results in a narrowed optical bandgap(E_(g)^(opt)) of 1.38 eV and a near-infrared absorption to 900 nm. When BDTIC is paired with donor polymer PBDB-T to fabricate organic solar cells, the optimized device achieves a best power conversion efficiency of 12.1% with a short-circuit current density of 20.0 mA·cm^(-2) and an open-circuit voltage of 0.88 V. The photovoltaic performance benefits from the broad absorption, weak bimolecular recombination, efficient charge separation and collection, and favorable blend morphology. This work demonstrates that thienopyrroleexpanded benzo[1,2-b:4,5-b′]dithiophene unit(heptacyclic S,N-heteroacene) is a promising building unit to construct high-performance NFAs by enhancing the intramolecular charge transfer effect, broadening absorption as well as maintaining good intermolecular stacking property. 展开更多
关键词 Organic solar cells(OSCs) Non-fullerene acceptors(NFAs) Heptacyclic S N-heteroacene
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