The presence of malignant ascites in colorectal cancer(CRC)patients is associated with a poor prognosis,a high risk of recurrence,and resistance to chemotherapy and immune therapy[1–3].Understanding the complex inter...The presence of malignant ascites in colorectal cancer(CRC)patients is associated with a poor prognosis,a high risk of recurrence,and resistance to chemotherapy and immune therapy[1–3].Understanding the complex interactions among different kinds of cells and the ecosystem of peritoneal metastasized colorectal cancer(pmCRC)ascites may provide insights into effective treatment strategies.展开更多
基金financial support from the National Key R&D Program of China(No.2019YFA0110601)National Natural Science Foundation of China(No.81571827)+5 种基金Natural Science Foundation Project of Shanghai Science and Technology Commission(SKW2030)Excellent Discipline Reserve Talent Plan of Tongji Hospital Affiliated to Tongji University(HBRC2014)Clinical research Project of Tongji Hospital Affiliated to Tongji University(ITJ-ZD-2104)Key talent introduction project of Tongji Hospital Affiliated to Tongji University(RCQD2102)Talent project of Tongji Hospital Affiliated to Tongji University(GJPY2111)Shanghai Tongji Hospital special disease database construction project(TJ-DB-2105).
文摘The presence of malignant ascites in colorectal cancer(CRC)patients is associated with a poor prognosis,a high risk of recurrence,and resistance to chemotherapy and immune therapy[1–3].Understanding the complex interactions among different kinds of cells and the ecosystem of peritoneal metastasized colorectal cancer(pmCRC)ascites may provide insights into effective treatment strategies.
