The deformations and stresses of a rotating cylindrical hollow disk made of incompressible functionally-graded hyper-elastic material are theoretically analyzed based on the finite elasticity theory.The hyper-elastic ...The deformations and stresses of a rotating cylindrical hollow disk made of incompressible functionally-graded hyper-elastic material are theoretically analyzed based on the finite elasticity theory.The hyper-elastic material is described by a new micro-macro transition model.Specially,the material shear modulus and density are assumed to be a function with a power law form through the radial direction,while the material inhomogeneity is thus reflected on the power index m.The integral forms of the stretches and stress components are obtained.With the obtained complicated integral forms,the composite trapezoidal rule is utilized to derive the analytical solutions,and the explicit solutions for both the stretches and the stress components are numerically obtained.By comparing the results with two classic models,the superiority of the model in our work is demonstrated.Then,the distributions of the stretches and normalized stress components are discussed in detail under the effects of m.The results indicate that the material inhomogeneity and the rotating angular velocity have significant effects on the distributions of the normalized radial and hoop stress components and the stretches.We believe that by appropriately choosing the material inhomogeneity and configuration parameters,the functionally-graded material(FGM)hyper-elastic hollow cylindrical disk can be designed to meet some unique requirements in the application fields,e.g.,soft robotics,medical devices,and conventional aerospace and mechanical industries.展开更多
The multiscale micro-nano pores in coal can result in the ultra-low permeability of coal,which restricts the efficiency of gas extraction.It is difficult for the conventional seepage-enhancement measures to affect the...The multiscale micro-nano pores in coal can result in the ultra-low permeability of coal,which restricts the efficiency of gas extraction.It is difficult for the conventional seepage-enhancement measures to affect the nanoscale pores within the coal matrix.Thermal stimulation can reach deep into the micro-nano pores within coal matrix to improve the permeability.Therefore,it is important to study the diffusivity and permeability of the multiscale micro-nano pores at different temperatures.In this study,the experiments of diffusion-seepage measured by the methods of GRI(Gas Research Institution)and steady-state were conducted using a cylindrical coal at different temperatures and pressures.The experimental results show that the apparent diffusion coefficient of cylindrical coal is not constant but variable dynamically;and the classical diffusion model fails to describe the full-time process of gas flow accurately.On this basis,a model of multiscale dynamic apparent diffusion-seepage that can accurately describe the full-time flow process was proposed.As is observed,the apparent permeability attenuates dynamically with time without stress loading,and the initial apparent permeability and the attenuation coefficient increase monotonically with the rise of temperature.Under the stress constraint,the steady-state permeability increases after a decrease as the temperature rises,displaying a“U-shaped”pattern.Without stress constraint,the increasing temperature causes the exterior multiscale pores to expand outward by different degrees so as to increase permeability,while the interior micro-nano pores show three inward and outward expansion mechanisms.Under stress constraint,at low temperature and high effective stress,the increasing temperature causes pores to expand inward and the permeability decreases accordingly.When temperature continues to increase,coal expands outward because the effective stress is counteracted by the thermal stress,leading to an increase in permeability.This study is of significance for thermal gas extraction engineering.展开更多
<i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i><span style="font-family:Verdana;"></span><span style="font-family:;" "=&q...<i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i><span style="font-family:Verdana;"></span><span style="font-family:;" "=""><span style="font-family:Verdana;"> used as an analgesic and anti-inflammatory. It is often used not only in Mongolian medicine but also in traditional Chinese medicine. However, there are few studies on its impact of inflammatory cytokines. This study explored the effects of </span><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i> <i><span style="font-family:Verdana;">in vitro</span></i><span style="font-family:Verdana;"></span></i></span><span style="font-family:Verdana;"> used human colon cancer (Caco-2) cells. Cytotoxicity was assessed by measuring effects on expression of IL-1</span><i><span style="font-family:Verdana;"><span style="white-space:nowrap;">β</span></span></i><span style="font-family:Verdana;">, IL-6, IL-8, and TNF-</span><i><span style="font-family:Verdana;"><span style="white-space:nowrap;">α</span></span></i><span style="font-family:Verdana;"> used enzyme-linked immun</span><span style="font-family:Verdana;">o</span><span style="font-family:;" "=""><span style="font-family:Verdana;">sorbent assay (ELISA). </span><span><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">In vitro</span></i><span style="font-family:Verdana;"></span></i></span></span><span style="font-family:Verdana;"> study demonstrated that incubation of Caco-2 cells with some kinds of</span><i> </i><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i><span style="font-family:Verdana;"></span></i><span style="font-family:Verdana;"> at some concentrations inhibit secretion of TNF-</span><i><span style="font-family:Verdana;"><span style="white-space:nowrap;">α</span></span></i><span style="font-family:Verdana;"> and FAXIU </span><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">ACONITUM</span></i> <i><span style="font-family:Verdana;">KUSNEZOFFII</span></i><span style="font-family:Verdana;"></span></i><span style="font-family:Verdana;"> could inhibit the secretion of IL-1</span><i><span style="font-family:Verdana;"><span style="white-space:nowrap;">β</span></span></i><span style="font-family:Verdana;">. While IL-6 and IL-8 levels were unaffected after 24 h of treatment with </span><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i><span style="font-family:Verdana;"><i></i></span><i><span style="font-family:Verdana;">, </span></i></i><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;">qujian </span><i><i><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i><span style="font-family:Verdana;"><i></i></span><i><span style="font-family:Verdana;">, </span></i></i></i></i><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;">faxiu </span><i><i><i><i><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i><span style="font-family:Verdana;"></span></i><span style="font-family:Verdana;">.</span></i></i></i></i>展开更多
A fully dense carbon nanotubes (CNTs) reinforced AlSi matrix composite with the multiscale nacre-like architecture was designed and successfully realized by flake powder metallurgy followed by cold spraying (CS). The ...A fully dense carbon nanotubes (CNTs) reinforced AlSi matrix composite with the multiscale nacre-like architecture was designed and successfully realized by flake powder metallurgy followed by cold spraying (CS). The nanolaminated and ultrafine-grained structure initially created in the CNT/AlSi flaky powder was perfectly conserved, due to the typical ‘cold’ feature of CS. As discussed based on finite element analysis and single splat observation, self-alignment behavior of the flaky powders during impact also allowed the formation of the microlaminated structure. Hence, the scalable CS technique opens a new avenue for bioinspired material design and fabrication with complex shape.展开更多
Gene expression profile changes in brain regions following traumatic brain injury at the gene level cannot sufficiently elucidate gene expression time,expression amount,protein post-translational processing or modific...Gene expression profile changes in brain regions following traumatic brain injury at the gene level cannot sufficiently elucidate gene expression time,expression amount,protein post-translational processing or modification.Therefore,it is necessary to quantitatively analyze the gene expression profile using proteomic techniques.In the present study,we established a rat model of closed brain injury using Marmarou's weight-drop device,and investigated hippocampal differential protein expression using two-dimensional gel electrophoresis and surface-enhanced laser desorption ionization-time of flight-mass spectrometry.A total of 364 protein peaks were detected on weak cation exchange-2 protein chips,including 37 differential protein peaks.345 protein peaks were detected on immobilized metal affinity capture arrays-Cu,including 12 differential protein peaks Further examination of these differential proteins revealed that glucose-regulated protein and proteasome subunit alpha type 3 expression were significantly upregulated post-injury.These results indicate that brain injury can alter protein expression in the hippocampus,and that glucose-regulated protein and proteasome subunit alpha type 3 are closely associated with the occurrence and development of traumatic brain injury.展开更多
The structure of a canalizing function is discussed.Using a new matrix product,namely semitensor product,the logical function is expressed in its matrix form.From its matrix expression,a criterion is obtained to test ...The structure of a canalizing function is discussed.Using a new matrix product,namely semitensor product,the logical function is expressed in its matrix form.From its matrix expression,a criterion is obtained to test whether a logical function is a canalizing function.Then a formula is obtained to calculate the number of canalizing functions.Moreover,an algorithm is presented to generate canalizing functions.Finally,some results obtained are extended to seminested canalizing functions.展开更多
Organic active units often transform into radical intermediates during the redox processes but exhibit poor cycling stability due to the uncontrollable redox of the radicals. Herein, we report a facile and efficient s...Organic active units often transform into radical intermediates during the redox processes but exhibit poor cycling stability due to the uncontrollable redox of the radicals. Herein, we report a facile and efficient strategy to modulate the molecular orbital energies, charge transport capacities, and spin electron densities of the active units in covalent organic frameworks(COFs) via regulating the conjugated unit size to optimize the redox activity and stability of the organic radicals. COFs based on different imide conjugated units exhibit tunable discharge voltages, rate performance and cycling stabilities. Detailed characterizations and theoretical calculation reveal that imide radicals are the important active intermediates during the redox processes of these COFs. Specifically, increasing the size of the imide conjugated units could effectively delocalize the radical electrons and improve the stability of the COFs electrodes. This study offers a very effective strategy to modulate the redox chemistry of organic materials for electrochemical energy storage.展开更多
On average,five to six storms occur in the Qiongzhou Strait every year,causing significant damage to coastal geomorphology and several property losses.Tropical Storm Bebinca is the most unusual and complex storm event...On average,five to six storms occur in the Qiongzhou Strait every year,causing significant damage to coastal geomorphology and several property losses.Tropical Storm Bebinca is the most unusual and complex storm event that has occurred in this region over the last 10 years.To detect the high-frequency beachface responses to the storm,a pressure sensor was deployed in the surf zone to record the free sea surface height,and the heights of grid pile points on the beachface were measured manually to determine beach elevation changes during this storm.Empirical Mode Decomposition and related analysis techniques were used to analyze the high-frequency topography and wave data.The results showed that:(1)the beachface response process occurred in three stages.The first stage was the rapid response stage,wherein the spring tide berm began to erode significantly,and the front edge of the beach berm reacted closely.The two beach sections resisted the harmful energy of the main storm.In the second stage,the beach slope increased after a large sediment loss on the beach berm and its front edge.To adapt to the storm energy,the beach at the low tide line began to erode,and the beach slope decreased.In the third stage,after the storm turned,the wave energy was significantly attenuated,and the beach berm eroded to resist the residual wave energy.The beachface began to oscillate and recover.(2)The main wave surface was the superimposed product of a few internal mode functions.Similar results were observed in beachface changes.High-frequency driving factors determine the local characteristics of beach evolution,and low-frequency driving factors determine the beach evolution trend.(3)The response of sediment to the storm was not a single sea-transportation,but a single-or two-way conversion driven by factors such as wave energy,swash flow,and secondary wave breaking.(4)TheΩ-RTR model is not completely applicable to beach states that undergo rapid changes during storms.Therefore,it is necessary to carry out further research on beach state identification during storms.展开更多
PtRu/SnO_2/C catalyst was prepared in a polyol process, followed by reduction treatment and alkaline etching. X-ray diffraction, transmission electron microscope with energy dispersive spectrometer and Xray photoelect...PtRu/SnO_2/C catalyst was prepared in a polyol process, followed by reduction treatment and alkaline etching. X-ray diffraction, transmission electron microscope with energy dispersive spectrometer and Xray photoelectron spectroscopy were used to characterize the morphology, structure and composition of the catalysts. CO and methanol electro-oxidation activities of the catalysts were evaluated by CO stripping voltammetry, cyclic voltammetry and chronoamperometry measurements. Reduction treatment of the prepared PtRuSnO_2/C catalyst in a polyol process induced the enrichment of Sn on the surface, inhibiting methanol dissolution and CO adsorption on Pt. Alkaline etching removed Sn or SnO_x and thus exposed PtRu on the surface, resulting in enhanced activities for CO and methanol electro-oxidation due to the synergy effects of PtRu on the surface and Sn species beneath.展开更多
Superplastic properties and microstructural evolution of a Ti-24Al-14Nb-3V-0.5Mo (at. pct) intermetallic alloy were studied. Optimum superplastic properties were obtained for temperatures in the interval 960℃≤5 T≤5...Superplastic properties and microstructural evolution of a Ti-24Al-14Nb-3V-0.5Mo (at. pct) intermetallic alloy were studied. Optimum superplastic properties were obtained for temperatures in the interval 960℃≤5 T≤5980℃. The apparent activation energy in the superplastic regime was determined and the deformation mechanism was also discussed. Based on the studies, a curve panel with three sheets sandwich structure was fabricated successfully. The microstructures corresponding to different strain in the part were also studied.展开更多
Anthocyanins are valuable compounds in red-fleshed apples.The MdMYB10 transcription factor is an important regulator of the anthocyanin synthesis pathway.However,other transcription factors are key components of the c...Anthocyanins are valuable compounds in red-fleshed apples.The MdMYB10 transcription factor is an important regulator of the anthocyanin synthesis pathway.However,other transcription factors are key components of the complex network controlling anthocyanin synthesis and should be more thoroughly characterized.In this study,we used a yeast-based screening technology to identify MdNAC1 as a transcription factor that positively regulates anthocyanin synthesis.The overexpression of MdNAC1 in apple fruits and calli significantly promoted the accumulation of anthocyanins.In binding experiments,we demonstrated that MdNAC1 combines with the bZIP-type transcription factor MdbZIP23 to activate the transcription of MdMYB10 and MdUFGT.Our analyses also indicated that the expression of MdNAC1 is strongly induced by ABA because of the presence of an ABRE cis-acting element in its promoter.Additionally,the accumulation of anthocyanins in apple calli co-transformed with MdNAC1 and MdbZIP23 increased in the presence of ABA.Therefore,we revealed a novel anthocyanin synthesis mechanism involving the ABA-induced transcription factor MdNAC1 in red-fleshed apples.展开更多
Coastal erosion on islands is increasing due to sea level rise,frequent extreme events,and anthropogenic activities.However,studies on the multifactorial coastal erosion risk and the vulnerability of islands are limit...Coastal erosion on islands is increasing due to sea level rise,frequent extreme events,and anthropogenic activities.However,studies on the multifactorial coastal erosion risk and the vulnerability of islands are limited.In this study,the Coastal Erosion Risk Assessment(CERA)method was applied for the first time to the study area in China to assess the erosion risk on the coast of Hainan Island;to explore the effects of coastal ocean dynamics,sediment movement characteristics,and anthropogenic construction;and to discuss the suitability of the method and countermeasures for coastal protection.The results show that the coast of Hainan Island shows high sensitivity,high value,low exposure,and moderate erosion.The whole island showed high vulnerability but low erosion risk,with the eastern region being more affected by erosion,particularly the eastern side of Wulong Port and Yalin Bay in Wenchang,and the shore section of Yalong Bay in Sanya,having a very high risk of coastal erosion.In addition,Monte Carlo simulation was used to check the applicability of the CERA method,and it was found that the rate of shoreline change,population density,and number of storms significantly contributed to coastal erosion,but only the short-term effects of sea level rise were considered.The effects of sea level rise and sediment grain size were primarily analyzed as influencing factors.The effects of sea level rise continue to strengthen,with coastal retreat expected to be greater than 2 m by the mid-21st century.Moreover,Hainan Island is primarily composed of the fine and medium sand types,which have little resistance to coastal erosion.Currently,the impact of sediment grain size is rarely considered in coastal erosion risk assessment studies.However,it can be incorporated into the indicator system in the future,and the spatial variation of indicators can be fully considered to strengthen the refinement study.展开更多
Upland cotton(Gossypium hirsutum)is the most important plant producing natural fibers for the textile industry.In this study,we first investigated the phenotypic variation of seven agronomic traits of 273 diverse cott...Upland cotton(Gossypium hirsutum)is the most important plant producing natural fibers for the textile industry.In this study,we first investigated the phenotypic variation of seven agronomic traits of 273 diverse cotton accessions in the years 2017 and 2018,which were from 18 geographical regions.We found large variations among the traits in different geographical regions and only half of the traits in either years 2017 or 2018 followed a normal distribution.We then genotyped the collection with 81,612 high quality SNPs.Phylogenetic tree and population structure revealed a diverse genetic structure of the core collection,and geographical diversification was an important factor,but account for part of the variances of genetic diversification.We then performed genome-wide association study for the seven traits in the years 2017 and 2018,and the average values of each trait in the two years,respectively.We identified a total of 19 significant marker-trait associations and found that Pollen Ole e 1 allergen/extension could be the candidate gene associated with the fall-off cotton bolls from the last three branches.In addition,large variations were observed for the heritability of traits in the years 2017 and 2018.These results provide new potential candidate genes for further functional validation,which could be useful for genetic improvement and breeding of new cotton cultivars with better agronomic performances.展开更多
Realizing the uniform dispersion of nanocarbons such as carbon nanotube and graphene in metals, is an essential prerequisite to fully exhibit their enhancement effect in mechanical, thermal, and electrical properties ...Realizing the uniform dispersion of nanocarbons such as carbon nanotube and graphene in metals, is an essential prerequisite to fully exhibit their enhancement effect in mechanical, thermal, and electrical properties of metal matrix composites(MMCs). In this work, we propose an effective method to achieve uniform distribution of nanocarbons in various metal flakes through a slurry-based method. It relies on the electrostatic interactions between the negatively charged nanocarbons and the positively charged metal flakes when mixed in slurry. For case study, flake metal powders(Al, Mg, Ti,Fe, and Cu) were positively charged in aqueous suspension by spontaneous ionization or cationic surface modification. While nanocarbons, given examples as carboxylic multi-walled carbon nanotubes, pristine single-walled carbon nanotube, and carbon nanotube–graphene oxide hybrid were negatively charged by the ionization of oxygen-containing functional groups or anionic surfactant. It was found that through the electrostatic interaction mechanism, all kinds of nanocarbons can be spontaneously and efficiently adsorbed onto the surface of various metal flakes. The development of such a versatile method would provide us great opportunities to fabricate advanced MMCs with appealing properties.展开更多
基金supported by the National Natural Science Foundation of China(No.11972144)the Shanxi Province Specialized Research and Development Breakthrough in Key Core and Generic Technologies(Key Research and Development Program)(No.2020XXX017)the Fundamental Research Program of Shanxi Province of China(No.202203021211134)。
文摘The deformations and stresses of a rotating cylindrical hollow disk made of incompressible functionally-graded hyper-elastic material are theoretically analyzed based on the finite elasticity theory.The hyper-elastic material is described by a new micro-macro transition model.Specially,the material shear modulus and density are assumed to be a function with a power law form through the radial direction,while the material inhomogeneity is thus reflected on the power index m.The integral forms of the stretches and stress components are obtained.With the obtained complicated integral forms,the composite trapezoidal rule is utilized to derive the analytical solutions,and the explicit solutions for both the stretches and the stress components are numerically obtained.By comparing the results with two classic models,the superiority of the model in our work is demonstrated.Then,the distributions of the stretches and normalized stress components are discussed in detail under the effects of m.The results indicate that the material inhomogeneity and the rotating angular velocity have significant effects on the distributions of the normalized radial and hoop stress components and the stretches.We believe that by appropriately choosing the material inhomogeneity and configuration parameters,the functionally-graded material(FGM)hyper-elastic hollow cylindrical disk can be designed to meet some unique requirements in the application fields,e.g.,soft robotics,medical devices,and conventional aerospace and mechanical industries.
基金Doctoral Foundation of Henan Polytechnic University,Grant/Award Number:B2021-7Key Science and Technology Project of Henan Province,Grant/Award Number:222102320017+3 种基金State Key Laboratory Cultivation Base for Gas Geology and Gas Control(Henan Polytechnic University),Grant/Award Number:WS2021A06National Natural Science Foundation of China,Grant/Award Number:52174173Key Scientific Research Projects of Colleges and Universities in Henan Province,Grant/Award Number:22B620002Fundamental Research Funds for the Universities of Henan Province,Grant/Award Number:NSFRF180305。
文摘The multiscale micro-nano pores in coal can result in the ultra-low permeability of coal,which restricts the efficiency of gas extraction.It is difficult for the conventional seepage-enhancement measures to affect the nanoscale pores within the coal matrix.Thermal stimulation can reach deep into the micro-nano pores within coal matrix to improve the permeability.Therefore,it is important to study the diffusivity and permeability of the multiscale micro-nano pores at different temperatures.In this study,the experiments of diffusion-seepage measured by the methods of GRI(Gas Research Institution)and steady-state were conducted using a cylindrical coal at different temperatures and pressures.The experimental results show that the apparent diffusion coefficient of cylindrical coal is not constant but variable dynamically;and the classical diffusion model fails to describe the full-time process of gas flow accurately.On this basis,a model of multiscale dynamic apparent diffusion-seepage that can accurately describe the full-time flow process was proposed.As is observed,the apparent permeability attenuates dynamically with time without stress loading,and the initial apparent permeability and the attenuation coefficient increase monotonically with the rise of temperature.Under the stress constraint,the steady-state permeability increases after a decrease as the temperature rises,displaying a“U-shaped”pattern.Without stress constraint,the increasing temperature causes the exterior multiscale pores to expand outward by different degrees so as to increase permeability,while the interior micro-nano pores show three inward and outward expansion mechanisms.Under stress constraint,at low temperature and high effective stress,the increasing temperature causes pores to expand inward and the permeability decreases accordingly.When temperature continues to increase,coal expands outward because the effective stress is counteracted by the thermal stress,leading to an increase in permeability.This study is of significance for thermal gas extraction engineering.
文摘<i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i><span style="font-family:Verdana;"></span><span style="font-family:;" "=""><span style="font-family:Verdana;"> used as an analgesic and anti-inflammatory. It is often used not only in Mongolian medicine but also in traditional Chinese medicine. However, there are few studies on its impact of inflammatory cytokines. This study explored the effects of </span><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i> <i><span style="font-family:Verdana;">in vitro</span></i><span style="font-family:Verdana;"></span></i></span><span style="font-family:Verdana;"> used human colon cancer (Caco-2) cells. Cytotoxicity was assessed by measuring effects on expression of IL-1</span><i><span style="font-family:Verdana;"><span style="white-space:nowrap;">β</span></span></i><span style="font-family:Verdana;">, IL-6, IL-8, and TNF-</span><i><span style="font-family:Verdana;"><span style="white-space:nowrap;">α</span></span></i><span style="font-family:Verdana;"> used enzyme-linked immun</span><span style="font-family:Verdana;">o</span><span style="font-family:;" "=""><span style="font-family:Verdana;">sorbent assay (ELISA). </span><span><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">In vitro</span></i><span style="font-family:Verdana;"></span></i></span></span><span style="font-family:Verdana;"> study demonstrated that incubation of Caco-2 cells with some kinds of</span><i> </i><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i><span style="font-family:Verdana;"></span></i><span style="font-family:Verdana;"> at some concentrations inhibit secretion of TNF-</span><i><span style="font-family:Verdana;"><span style="white-space:nowrap;">α</span></span></i><span style="font-family:Verdana;"> and FAXIU </span><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">ACONITUM</span></i> <i><span style="font-family:Verdana;">KUSNEZOFFII</span></i><span style="font-family:Verdana;"></span></i><span style="font-family:Verdana;"> could inhibit the secretion of IL-1</span><i><span style="font-family:Verdana;"><span style="white-space:nowrap;">β</span></span></i><span style="font-family:Verdana;">. While IL-6 and IL-8 levels were unaffected after 24 h of treatment with </span><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i><span style="font-family:Verdana;"><i></i></span><i><span style="font-family:Verdana;">, </span></i></i><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;">qujian </span><i><i><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i><span style="font-family:Verdana;"><i></i></span><i><span style="font-family:Verdana;">, </span></i></i></i></i><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;">faxiu </span><i><i><i><i><span style="font-family:Verdana;"><i></i></span><i><i><span style="font-family:Verdana;">Aconitum kusnezoffii</span></i><span style="font-family:Verdana;"></span></i><span style="font-family:Verdana;">.</span></i></i></i></i>
基金financial support from China Scholarship Council for his Ph.D. projectThe TEM facility in Lille, France, is supported by the Conseil Regional du Nord-Pas de Calais and the European Regional Development Fund
文摘A fully dense carbon nanotubes (CNTs) reinforced AlSi matrix composite with the multiscale nacre-like architecture was designed and successfully realized by flake powder metallurgy followed by cold spraying (CS). The nanolaminated and ultrafine-grained structure initially created in the CNT/AlSi flaky powder was perfectly conserved, due to the typical ‘cold’ feature of CS. As discussed based on finite element analysis and single splat observation, self-alignment behavior of the flaky powders during impact also allowed the formation of the microlaminated structure. Hence, the scalable CS technique opens a new avenue for bioinspired material design and fabrication with complex shape.
基金the National Natural Science Foundation of China,No. 30471934
文摘Gene expression profile changes in brain regions following traumatic brain injury at the gene level cannot sufficiently elucidate gene expression time,expression amount,protein post-translational processing or modification.Therefore,it is necessary to quantitatively analyze the gene expression profile using proteomic techniques.In the present study,we established a rat model of closed brain injury using Marmarou's weight-drop device,and investigated hippocampal differential protein expression using two-dimensional gel electrophoresis and surface-enhanced laser desorption ionization-time of flight-mass spectrometry.A total of 364 protein peaks were detected on weak cation exchange-2 protein chips,including 37 differential protein peaks.345 protein peaks were detected on immobilized metal affinity capture arrays-Cu,including 12 differential protein peaks Further examination of these differential proteins revealed that glucose-regulated protein and proteasome subunit alpha type 3 expression were significantly upregulated post-injury.These results indicate that brain injury can alter protein expression in the hippocampus,and that glucose-regulated protein and proteasome subunit alpha type 3 are closely associated with the occurrence and development of traumatic brain injury.
基金supported by the National Natural Science Foundation of China (No.60674022,60736022,60821091)
文摘The structure of a canalizing function is discussed.Using a new matrix product,namely semitensor product,the logical function is expressed in its matrix form.From its matrix expression,a criterion is obtained to test whether a logical function is a canalizing function.Then a formula is obtained to calculate the number of canalizing functions.Moreover,an algorithm is presented to generate canalizing functions.Finally,some results obtained are extended to seminested canalizing functions.
基金supports from the Basic Research Project of the Science and Technology Innovation Commission of Shenzhen (No. JCYJ20200109141640095)the Shenzhen Key Laboratory of Interfacial Science and Engineering of Materials (No. ZDSYS20200421111401738)+3 种基金the Leading Talents of Guangdong Province Program (No. 2016LJ06C536)the GuangdongHong Kong-Macao Joint Laboratory (No. 2019B121205001)the National Natural Science Foundation of China (No. 21875097)the support from the Hong Kong Research Grants Council (Project number CityU 11218420)。
文摘Organic active units often transform into radical intermediates during the redox processes but exhibit poor cycling stability due to the uncontrollable redox of the radicals. Herein, we report a facile and efficient strategy to modulate the molecular orbital energies, charge transport capacities, and spin electron densities of the active units in covalent organic frameworks(COFs) via regulating the conjugated unit size to optimize the redox activity and stability of the organic radicals. COFs based on different imide conjugated units exhibit tunable discharge voltages, rate performance and cycling stabilities. Detailed characterizations and theoretical calculation reveal that imide radicals are the important active intermediates during the redox processes of these COFs. Specifically, increasing the size of the imide conjugated units could effectively delocalize the radical electrons and improve the stability of the COFs electrodes. This study offers a very effective strategy to modulate the redox chemistry of organic materials for electrochemical energy storage.
基金The National Natural Science Foundation of China under contract Nos 42176167 and 41676079the Project of Enhancing School with Innovation,Guangdong Ocean University under contract No.Q18307.
文摘On average,five to six storms occur in the Qiongzhou Strait every year,causing significant damage to coastal geomorphology and several property losses.Tropical Storm Bebinca is the most unusual and complex storm event that has occurred in this region over the last 10 years.To detect the high-frequency beachface responses to the storm,a pressure sensor was deployed in the surf zone to record the free sea surface height,and the heights of grid pile points on the beachface were measured manually to determine beach elevation changes during this storm.Empirical Mode Decomposition and related analysis techniques were used to analyze the high-frequency topography and wave data.The results showed that:(1)the beachface response process occurred in three stages.The first stage was the rapid response stage,wherein the spring tide berm began to erode significantly,and the front edge of the beach berm reacted closely.The two beach sections resisted the harmful energy of the main storm.In the second stage,the beach slope increased after a large sediment loss on the beach berm and its front edge.To adapt to the storm energy,the beach at the low tide line began to erode,and the beach slope decreased.In the third stage,after the storm turned,the wave energy was significantly attenuated,and the beach berm eroded to resist the residual wave energy.The beachface began to oscillate and recover.(2)The main wave surface was the superimposed product of a few internal mode functions.Similar results were observed in beachface changes.High-frequency driving factors determine the local characteristics of beach evolution,and low-frequency driving factors determine the beach evolution trend.(3)The response of sediment to the storm was not a single sea-transportation,but a single-or two-way conversion driven by factors such as wave energy,swash flow,and secondary wave breaking.(4)TheΩ-RTR model is not completely applicable to beach states that undergo rapid changes during storms.Therefore,it is necessary to carry out further research on beach state identification during storms.
基金financially supported by the project of National Scientific Fund of China(Grant no.201403023)Specialized Research Fund for the Doctoral Program of Higher Education of China(Grant no.20122124120004)
文摘PtRu/SnO_2/C catalyst was prepared in a polyol process, followed by reduction treatment and alkaline etching. X-ray diffraction, transmission electron microscope with energy dispersive spectrometer and Xray photoelectron spectroscopy were used to characterize the morphology, structure and composition of the catalysts. CO and methanol electro-oxidation activities of the catalysts were evaluated by CO stripping voltammetry, cyclic voltammetry and chronoamperometry measurements. Reduction treatment of the prepared PtRuSnO_2/C catalyst in a polyol process induced the enrichment of Sn on the surface, inhibiting methanol dissolution and CO adsorption on Pt. Alkaline etching removed Sn or SnO_x and thus exposed PtRu on the surface, resulting in enhanced activities for CO and methanol electro-oxidation due to the synergy effects of PtRu on the surface and Sn species beneath.
文摘Superplastic properties and microstructural evolution of a Ti-24Al-14Nb-3V-0.5Mo (at. pct) intermetallic alloy were studied. Optimum superplastic properties were obtained for temperatures in the interval 960℃≤5 T≤5980℃. The apparent activation energy in the superplastic regime was determined and the deformation mechanism was also discussed. Based on the studies, a curve panel with three sheets sandwich structure was fabricated successfully. The microstructures corresponding to different strain in the part were also studied.
基金supported by the National key Research and Development Program of China (2019YFC1709500)the National Collaboration Project of Critical Illness by Integrating Chinese Medicine and Western Medicine+8 种基金the Project of Heilongjiang Province Innovation Team “Tou Yan”the Yi-Xun Liu and Xiao-Ke Wu Academician Workstationthe Innovation Team of Reproductive Technique with Integrative Chinese Medicine and Western Medicine in Xuzhou City, ChinaHeilongjiang University of Chinese Medicine from the National Clinical Trial BaseHeilongjiang Provincial Clinical Research Center for Ovary Diseasesthe Research Grant Council (T13-602/21-N, C5045-20EF, and 14122021)Food and Health Bureau in Hong Kong, China (06171026)supported by a National Health and Medical Research Council (NHMRC) Investigator grant (GNT1176437)travel support from Merck.
基金This study was supported by the Natural Science Foundation of Shandong Province(ZR2020QC144,ZR2022MC017)the National Natural Science Foundation of China(32002002)the Key Research and Develop ment Programs of Shandong Provence(2021LZGC024).
文摘Anthocyanins are valuable compounds in red-fleshed apples.The MdMYB10 transcription factor is an important regulator of the anthocyanin synthesis pathway.However,other transcription factors are key components of the complex network controlling anthocyanin synthesis and should be more thoroughly characterized.In this study,we used a yeast-based screening technology to identify MdNAC1 as a transcription factor that positively regulates anthocyanin synthesis.The overexpression of MdNAC1 in apple fruits and calli significantly promoted the accumulation of anthocyanins.In binding experiments,we demonstrated that MdNAC1 combines with the bZIP-type transcription factor MdbZIP23 to activate the transcription of MdMYB10 and MdUFGT.Our analyses also indicated that the expression of MdNAC1 is strongly induced by ABA because of the presence of an ABRE cis-acting element in its promoter.Additionally,the accumulation of anthocyanins in apple calli co-transformed with MdNAC1 and MdbZIP23 increased in the presence of ABA.Therefore,we revealed a novel anthocyanin synthesis mechanism involving the ABA-induced transcription factor MdNAC1 in red-fleshed apples.
基金The National Natural Science Foundation of China under contract No.42176167the Innovation Fund of Guangdong Ocean University under contract No.Q18307the Postgraduate Education Innovation Project of Guangdong Ocean University under contract No.202252.
文摘Coastal erosion on islands is increasing due to sea level rise,frequent extreme events,and anthropogenic activities.However,studies on the multifactorial coastal erosion risk and the vulnerability of islands are limited.In this study,the Coastal Erosion Risk Assessment(CERA)method was applied for the first time to the study area in China to assess the erosion risk on the coast of Hainan Island;to explore the effects of coastal ocean dynamics,sediment movement characteristics,and anthropogenic construction;and to discuss the suitability of the method and countermeasures for coastal protection.The results show that the coast of Hainan Island shows high sensitivity,high value,low exposure,and moderate erosion.The whole island showed high vulnerability but low erosion risk,with the eastern region being more affected by erosion,particularly the eastern side of Wulong Port and Yalin Bay in Wenchang,and the shore section of Yalong Bay in Sanya,having a very high risk of coastal erosion.In addition,Monte Carlo simulation was used to check the applicability of the CERA method,and it was found that the rate of shoreline change,population density,and number of storms significantly contributed to coastal erosion,but only the short-term effects of sea level rise were considered.The effects of sea level rise and sediment grain size were primarily analyzed as influencing factors.The effects of sea level rise continue to strengthen,with coastal retreat expected to be greater than 2 m by the mid-21st century.Moreover,Hainan Island is primarily composed of the fine and medium sand types,which have little resistance to coastal erosion.Currently,the impact of sediment grain size is rarely considered in coastal erosion risk assessment studies.However,it can be incorporated into the indicator system in the future,and the spatial variation of indicators can be fully considered to strengthen the refinement study.
基金supported by the Xinjiang Uygur Autonomous Region Major Science and Technology Project (2021A02001-3).
文摘Upland cotton(Gossypium hirsutum)is the most important plant producing natural fibers for the textile industry.In this study,we first investigated the phenotypic variation of seven agronomic traits of 273 diverse cotton accessions in the years 2017 and 2018,which were from 18 geographical regions.We found large variations among the traits in different geographical regions and only half of the traits in either years 2017 or 2018 followed a normal distribution.We then genotyped the collection with 81,612 high quality SNPs.Phylogenetic tree and population structure revealed a diverse genetic structure of the core collection,and geographical diversification was an important factor,but account for part of the variances of genetic diversification.We then performed genome-wide association study for the seven traits in the years 2017 and 2018,and the average values of each trait in the two years,respectively.We identified a total of 19 significant marker-trait associations and found that Pollen Ole e 1 allergen/extension could be the candidate gene associated with the fall-off cotton bolls from the last three branches.In addition,large variations were observed for the heritability of traits in the years 2017 and 2018.These results provide new potential candidate genes for further functional validation,which could be useful for genetic improvement and breeding of new cotton cultivars with better agronomic performances.
基金supported by the GDAS Special Project of Science and Technology Development(2020GDASYL-20200301003,2021GDASYL-20210103049,2020GDASYL-20200102021)the National Natural Science Foundation of China(3010300101,30970393,J1210002)the Biological Resources Program,Chinese Academy of Sciences(KFJ-BRP-017-26)。
基金the financial support of the National Basic Research Program(973 Program)(No.2012CB619600)the National Natural Science Foundation(Nos.51131004,51071100,51001071,51511130038,51501111,51471190)+1 种基金the National High-Tech R&D Program(863 Program)(No.2012AA030311)the research grant(Nos.14DZ2261200,15JC1402100,13PJ1404000,14520710100)from Shanghai government
文摘Realizing the uniform dispersion of nanocarbons such as carbon nanotube and graphene in metals, is an essential prerequisite to fully exhibit their enhancement effect in mechanical, thermal, and electrical properties of metal matrix composites(MMCs). In this work, we propose an effective method to achieve uniform distribution of nanocarbons in various metal flakes through a slurry-based method. It relies on the electrostatic interactions between the negatively charged nanocarbons and the positively charged metal flakes when mixed in slurry. For case study, flake metal powders(Al, Mg, Ti,Fe, and Cu) were positively charged in aqueous suspension by spontaneous ionization or cationic surface modification. While nanocarbons, given examples as carboxylic multi-walled carbon nanotubes, pristine single-walled carbon nanotube, and carbon nanotube–graphene oxide hybrid were negatively charged by the ionization of oxygen-containing functional groups or anionic surfactant. It was found that through the electrostatic interaction mechanism, all kinds of nanocarbons can be spontaneously and efficiently adsorbed onto the surface of various metal flakes. The development of such a versatile method would provide us great opportunities to fabricate advanced MMCs with appealing properties.
