In an attempt to search for novel compounds with agricultural bioactivity,a series of new polysubstituted pyridine derivatives,α-[2-methyl-5-cyano4-(furan-2-yl)-3-ethoxycarboxyl-pyridine-6-thio]acetamide 4a, 2-meth...In an attempt to search for novel compounds with agricultural bioactivity,a series of new polysubstituted pyridine derivatives,α-[2-methyl-5-cyano4-(furan-2-yl)-3-ethoxycarboxyl-pyridine-6-thio]acetamide 4a, 2-methyl-5-cyano-4-(furan-2-yl)-3-acetyl pyridine-6-thioethers [STHZ]5 and 6a were designed and synthesized by a three-step or one-step synthetic route.The structures of all the compounds prepared were confirmed by(elemental) analysis and 1H NMR.The preliminary bioassay results indicate that compound 4a possesses certain fungicidal and herbicidal activities.展开更多
文摘In an attempt to search for novel compounds with agricultural bioactivity,a series of new polysubstituted pyridine derivatives,α-[2-methyl-5-cyano4-(furan-2-yl)-3-ethoxycarboxyl-pyridine-6-thio]acetamide 4a, 2-methyl-5-cyano-4-(furan-2-yl)-3-acetyl pyridine-6-thioethers [STHZ]5 and 6a were designed and synthesized by a three-step or one-step synthetic route.The structures of all the compounds prepared were confirmed by(elemental) analysis and 1H NMR.The preliminary bioassay results indicate that compound 4a possesses certain fungicidal and herbicidal activities.