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A study of fluoride occurrence in groundwater and dental fluorosis in Nathenje, Lilongwe, Malawi 被引量:1
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作者 Kamoza W. Msonda William Masamba Emanuel Fabiano 《Chinese Journal Of Geochemistry》 EI CAS 2006年第B08期60-60,共1页
关键词 氟化物 地下水 氟中毒 马拉维 牙齿
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Groundwater Quality and Its Impact on Health: A Preliminary Evaluation of Dental Fluorosis in Julimes, Chihuahua, Mexico
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作者 Aida Verónica Ontiveros-Terrazas Alejandro Villalobos-Aragón +1 位作者 Vanessa Verónica Espejel-García Daphne Espejel-García 《Journal of Water Resource and Protection》 2020年第7期545-557,共13页
Medical Geology can be defined as the branch of geology dealing with the relationship between natural geological aspects and health in organisms (humans and animals), trying to determine the influence of ordinary envi... Medical Geology can be defined as the branch of geology dealing with the relationship between natural geological aspects and health in organisms (humans and animals), trying to determine the influence of ordinary environmental factors on the geographical distribution of health issues. The main goals of this research were: 1) to evaluate the severity of dental fluorosis (DF) and fluoride concentration in groundwater, used for human consumption, as an indicator of overexposure to fluorides, 2) to estimate the Community Fluorosis Index (CFI) in the Julimes municipality in Chihuahua, Mexico. Nine water samples were collected in four locations in the Julimes area: Hacienda Humboldt, La Regina, Colonia San Jose, and Julimes. Samples were collected and stored in accordance with the Mexican standard (NOM-014-SSA1-1993). All the samples exceeded the maximum permissible limit established in the modified Mexican standard (NOM-127-SSA1-1994) of 1.5 mgL<sup>-1</sup> for fluoride in water for human consumption. Average concentrations of 2.74 mgL<sup>-1</sup> were found in Colonia San Jose, 2.19 mgL<sup>-1</sup> in La Regina, 2.17 mgL<sup>-1</sup> in Julimes and 2.06 mgL<sup>-1</sup> in Hacienda Humboldt. Dental Fluorosis diagnosis was evaluated using the Dean Index and the CFI applied to residents. A total of 100 inhabitants were examined, with interviews and oral examinations also carried out. Dental Fluorosis prevalence was 92% overall for the municipality, while for Colonia San Jose was of 100%, of 88.89% for Hacienda Humboldt, 88.24% for Julimes and 96% for La Regina. Dental Fluorosis’ severity for the Julimes municipality was distributed as follows: 2% normal, 6% questionable, 8% very mild, 13% mild, 19% moderate, and 52% severe. An average CFI was found for the four localities of 3.02 points, with a very notable impact on public health. 展开更多
关键词 dental fluorosis Dean index Community fluorosis index CHIHUAHUA
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Assessment of the relationship between body mass index (BMI) and dental age
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作者 Maryam Zangouei-Booshehri Fatemeh Ezoddini-Ardakani +1 位作者 Hosein Agha Aghili Akbar Sharifi 《Health》 2011年第5期253-257,共5页
The aim of the study was to determine the rela-tionship between Body Mass Index (BMI) and accelerated dental development. The dental developmental ages of 100 children aged between 8 and 12 years were determined using... The aim of the study was to determine the rela-tionship between Body Mass Index (BMI) and accelerated dental development. The dental developmental ages of 100 children aged between 8 and 12 years were determined using the Demirjian method and panoramic radiographs. BMI status was determined for each subject on the basis of the system developed by the International Obesity Task Force. There was a significant direct relationship between dental development and BMI (P < 0.01). Obese children have a higher rate of dental development compared to normal children. CLINICAL RELEVANCE: This is an important variable to be considered when planning for dental and orthodontic treatments in obese children. Brief objectives statement: Overweight or obesity can accelerate dental development. Accelerated dental development in overweight children is important to be considered in pediatric dentistry and orthodontics. 展开更多
关键词 dental Age BODY Mass index (BMI) BONE Age OVERWEIGHT
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Fluorosis and Dental Caries in the Hydrogeological Environments of Southeastern Communities in the State of Morelos, Mexico
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作者 Gricelda G. Varela-González Alvaro García-Pérez +2 位作者 Rafael Huizar-Alvarez Maria Esther Irigoyen-Camacho Maria M. Espinoza-Jaramillo 《Journal of Environmental Protection》 2013年第9期994-1001,共8页
Objectives: 1) To identify the hydrogeological characteristics and fluoride (F-) concentration in drinking water in the southeast of the state of Morelos, Mexico, and 2) to estimate the association between the prevale... Objectives: 1) To identify the hydrogeological characteristics and fluoride (F-) concentration in drinking water in the southeast of the state of Morelos, Mexico, and 2) to estimate the association between the prevalence and severity of fluorosis, dental caries, and water F-?concentration. Methods: A hydrogeological model was developed to determine the vertical distribution of lithostratigraphic units, rocks’ hydraulic conductivities, and groundwater flow characteristics. A total of 649 schoolchildren from two communities received oral examinations. One community was located in an area with 0.75 mg F-/L in the water supply and the other in an area with 1.6 mg F-/L. Fluorosis was assessed using the Thylstrup & Fejerskov Index (TFI) and the dental caries were assessed with the decayed, missing, and filled teeth (DMFT) index. The region groundwater was extracted from an inter-granular aquifer consisting of volcano clasts of intermediate volcanic chemical composition. Results: Oral examinations showed that 32.35% of the children had severe forms of fluorosis (TFI ≥ 4) in the community with 1.60 mg F-/L and 7.8% in the 0.75 mg F-/L community (p < 0.0001). DMFT = 0.53 (±1.28) and 0.42 (±0.95) in the community with 1.60 mg F-/L and 0.75 mg F-/L, respectively (p = 0.2259). Conclusions: The increasing extraction of underground water was associated with deeper water flows and higher F-?concentration. In the community with high F-concentration, a third of the children showed objectionable levels of fluorosis. Adequate groundwater management actions are required to reduce fluorosis risk. 展开更多
关键词 FLUORIDE DRINKING Water fluorosis dental CARIES México
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Fluorine in Water and Dental Fluorosis in a Community of Queretaro State Mexico
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作者 Ma Lilia. A Juárez-López Rafael Huízar-álvarez +2 位作者 Nelly Molina-Frechero Francisco Murrieta-Pruneda Yazmin Cortés-Aguilera 《Journal of Environmental Protection》 2011年第6期744-749,共6页
The community La Llave, Queretaro State, Mexico, has not been identified by the sanitary authorities as living in a hazard area related to dental fluorosis. However;a high concentration of fluoride is found in their d... The community La Llave, Queretaro State, Mexico, has not been identified by the sanitary authorities as living in a hazard area related to dental fluorosis. However;a high concentration of fluoride is found in their drinking water causing them dental fluorosis. Physical-chemical analysis was carried out in the groundwater sources to determine the prevalence of dental fluorosis risk and caries accordingly to criteria of The World Health Organization, and 154 school children of ages 10 to 13 years were examined. As a result, 1.9 mg/L of fluorine concentration in drinking water was obtained;dental fluorosis presence was detected in the school children with an incidence of about 98%, in 47% of cases severe fluorosis with a dental caries index of 3.06 was traced. The groundwater sources in La Llave community contains fluorine above the limits dictated by Mexican regulations, producing serious repercussions on the health of school children, with an unnaturally high incidence of dental fluorosis. 展开更多
关键词 fluorosis DEAN index GROUNDWATER La Llave Querétaro Mexico
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The Impact of Salivary pH Value and Dental Caries Index on Periodontal Status among Adult Age Groups of Patients from Aseer Region, Saudi Arabia
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作者 Mohammed M. A. Abdullah Al-Abdaly Abdalkarim Ibrahim Mohammed Assiry 《Open Journal of Stomatology》 2020年第7期199-209,共11页
<b><span>Background:</span></b><span> The patients’ age is considered a modified risk factor that causes periodontal disease, dental caries, and their development.</span><b... <b><span>Background:</span></b><span> The patients’ age is considered a modified risk factor that causes periodontal disease, dental caries, and their development.</span><b><span> Objective:</span></b><span> The present study was designed to evaluate the impact of salivary pH value and dental caries index on periodontal status among adult age groups of patients from Aseer region, Saudi Arabia</span><span>.</span><span> </span><b><span>Methods:</span></b><span> A cross-sectional analysi</span><span>s carried out in the college of dentistry, King Khalid University on 750 </span><span>adult patients (400 males and 350 females). The adults patients were divided into three equal groups according to the patients’ age: group I (20 - 30 years), group I</span><span>I (31 - 40 years), and group III (41 - 50 years).</span><span> </span><span>Plaque index (PLI), gingi</span><span>val index (GI), clinical attachment loss (CAL), and the dental caries index (DMFT)</span><span> recorded as w</span><span>ell as salivary pH. All findings collected, then analyzed by an</span><span> ANOVA test and the t</span><span>-test. A p-value at <0.05 was considered a statistical significance level.</span><span> </span><b><span>R</span></b><b><span>esults:</span></b><b><span> </span></b><span>The clinical findings of the current study showed that there were statistically significant differences in the patients’ age of both males and females. Moreover, there were statistically significant diffe</span><span>rences in GI. On the other hand, there were highly statistically significant differences in PLI and DMFS, but there were no significant differences</span><span> in CAL of both males and females </span><span>Moreover, there were no statistically significant differences in salivary pH</span><span>.</span><span> </span><b><span>Conclusion:</span></b><span> We concluded that DMFT Index correlated to periodontal and oral hea</span><span>lth status and, it increased with the progression of the pat</span><span>ient’s age and</span><span> can be used in the epidemiological evaluation of periodontal and o</span><span>ral health status. 展开更多
关键词 Adult Age Groups of Patients dental Caries index Periodontal Status Salivary pH
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Relationships between daily total fluoride intake and dental fluorosis and dental caries 被引量:3
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作者 Quanyong Xiang Minghao Zhou +4 位作者 Ming Wu Xinya Zhou Li Lin Jiuning Huan Youxing Liang 《Journal of Nanjing Medical University》 2009年第1期33-39,共7页
Objective:To explore the relationships between the daily total intake of fluoride,dental fluorosis and dental caries. Methods: An epidemiological method was used to investigate the daily total intake of fluoride,denta... Objective:To explore the relationships between the daily total intake of fluoride,dental fluorosis and dental caries. Methods: An epidemiological method was used to investigate the daily total intake of fluoride,dental fluorosis,and dental caries among 236 and 290 children aged 8-13 years in a severe endemic area and in a non-fluorosis control area,respectively. The children were divided into eight subgroups according to each child’s estimated daily total intake of fluoride. The prevalence of dental fluorosis and dental caries in each group was calculated. Results: As expected,elevated levels of fluoride intake were significantly associated with a higher prevalence of dental fluorosis and an increasing amount of more severe defect dental fluorosis. When the daily total F intake was 2.78 mg/child/day,the prevalence of dental fluorosis was nearly 100%,with the prevalence of defect dental fluorosis increasing with increasing fluoride intake. There was also a significant negative(inverse) dose-response relationship between the daily total intake of fluoride and the overall preva-lence of dental caries,the prevalence of which decreased when the daily total intake of fluoride increased up to 3.32 mg/child/day. However,at higher levels of daily total intake of fluoride the prevalence of dental caries increased,giving rise to a U-shaped dose-response relationship curve. Conclusion: It is important to monitor total fluoride exposure and protect children from excessive fluoride intake,especially during the years of tooth development. 展开更多
关键词 氟化物 每日入口量 牙齿 氟中毒 牙龋
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Complete oral rehabilitation in a case with severe dental fluorosis
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作者 Nikhil Joshi Jayant Palaskar +1 位作者 Mahasweta Joshi Rahul Kathariya 《World Journal of Clinical Cases》 SCIE 2014年第12期938-942,共5页
The authors have presented a technique of full occlusal rehabilitation in a case of severe dental fluorosis. In this technique, maxillary and mandibular anterior teeth were simultaneously prepared and restored first. ... The authors have presented a technique of full occlusal rehabilitation in a case of severe dental fluorosis. In this technique, maxillary and mandibular anterior teeth were simultaneously prepared and restored first. This was followed by simultaneous preparation of maxillary and mandibular posterior teeth that were restored in canine guided occlusion. The technique and sequence followed here is unique and is not available in dental literature. This technique reduces number of appointments while fulfilling all objectives. Periodontal followup over 3 years was satisfactory. A restorative treatment protocol has been devised for fluorosis which will act as a guide for the dental practitioners. 展开更多
关键词 Occlusal REHABILITATION dental fluorosis Treatment protocol RESTORATIVE management Occlusal PLANE
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Effect of socio-demographic status on dental caries in pupils by using a multilevel hurdle model
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作者 Yunes Jahani Mohammad R. Eshraghian +4 位作者 Abbas R. Foroushani Keramat Nourijelyani Kazem Mohammad Arash Shahravan Mahin Alam 《Health》 2013年第7期1110-1116,共7页
Introduction: Dental caries is the most prevalent chronic disease among schoolchildren. We aimed to investigate the association between dental caries index and socio-demographic status in schoolchildren by using a mul... Introduction: Dental caries is the most prevalent chronic disease among schoolchildren. We aimed to investigate the association between dental caries index and socio-demographic status in schoolchildren by using a multilevel hurdle model. Materials and Methods: A cross-sectional epidemiological study was carried out on 906 primary school pupils in Kerman, Iran in 2012. The subjects were selected through a stratified cluster random sampling. At first, the whole target area was stratified according to two geographic areas, the north and south area. Then each area was stratified according to gender. In the next step, several schools were considered as clusters, which were selected randomly in each geographic area and gender strata. All the schoolchildren in these schools were included in this study as samples. Twelve-year-old pupils were examined for dental caries. The dependent variable in this study was the dmft/DMFT index. Eight variables, including socio-demographic information, were collected. Multilevel negative binomial hurdle model was employed for data analysis. Results: The prevalence of caries-free pupils was 30.1% and the mean dmft/DMFT was 3.6 ± 2.2. Negative binomial part of the adjusted model showed that the dmft/DMFT adjusted rate for females was 1.36 (95% CI: 1.10-1.79) times higher than males. Also, the dmft/DMFT adjusted rate for overweight pupils was 0.86 (95% CI: 0.74-0.98) times lower than those with normal weight. Logistic part of the adjusted model showed that the posibility of caries-free state in overweight pupils was 1.95 (95% CI: 1.22-3.11) times higher than those with normal weight. In addition, pupils whose fathers and mothers were workers and housewives, respectively, and those with a high maternal age were at a greater risk for caries experience than others (p < 0.05). Conclusion: BMI, gender, parent’s job and mother’s age at delivery were factors effecting on dental caries in schoolchildren. These pupils need more attention to dental care. 展开更多
关键词 MULTILEVEL HURDLE Model dental Caries SOCIO-DEMOGRAPHIC STATUS Primary School PUPILS dmft/DMFT index
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Therapeutic effect of neurogrowth factor in the treatment of gingival pain and swelling in patients with dental pulp necrosis after root canal therapy
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作者 Yan Li Hai-Yan Cheng 《Journal of Hainan Medical University》 2017年第20期150-153,共4页
Objective: To explore the clinical efficacy of neurogrowth factor in the treatment of gingival pain and swelling in patients with dental pulp necrosis after root canal therapy and the effect on the serum inflammatory ... Objective: To explore the clinical efficacy of neurogrowth factor in the treatment of gingival pain and swelling in patients with dental pulp necrosis after root canal therapy and the effect on the serum inflammatory cytokines. Methods: A total of 156 patients with gingival pain and swelling after root canal therapy due to dental pulp necrosis were included in the study and randomized into the control group (n=78) and teh treatment group (n=78). The patients in the control group were given metronidazole tablets. On the above basis, the patients in the treatment group were given local injection of neurogrowth factors. 10-day treatment was regarded as one course, and the patients were continuously treated for 2 courses. The improvement of clinical symptoms before and after treatment in the two groups was evaluated. Gingival sulcus index and serum inflammatory cytokines before and after treatment in the two groups were detected and compared. Results: When compared with before treatment, the periodontal soft tissue swelling, tooth mobility, and periapical pain scores after treatment in the two groups were significantly reduced, and those in the treatment group were significantly lower than those in the control group. When compared with before treatment, the gingival sulcus bleeding index 1 and 2 courses after treatment in the two groups was significantly reduced, and that 2 courses after treatment was significantly lower than that after 1 course treatment. The gingival sulcus bleeding index 1 and 2 courses after treatment in the treatment group was significantly lower than that in the control group. When compared with before treatment, the serum IL-8 and IL-6 levels after treatment in the two groups, and TNF-α level after treatment in the treatment group were significantly reduced, and the above indicators in the treatment group were significantly lower than those in the control group. Conclusions: The neurogrowth factors in the treatment of gingival pain and swelling in patients with dental pulp necrosis after root canal therapy can effectively improve the clinical symptoms, and inhibit the inflammatory reaction, with a significant efficacy. 展开更多
关键词 dental pulp necrosis Root CANAL therapy GINGIVAL PAIN and SWELLING Neurogrowth factor Inflammatory cytokine GINGIVAL SULCUS bleeding index
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Exploring the practice of common oral diseases among the patients visiting in the selected dental college and hospital in Bangladesh
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作者 Khalid Hasan Pasha Md.Fazlul Karim +4 位作者 Md.Mahmudur Rahman Ashek Elahi Noor Md.Mamunur Rashid Nahid Al Nomann Kazi Golam Mohiuddin 《Life Research》 2022年第4期1-5,共5页
Background:Having the ability to identify potential health risk factors such as lifestyle,ethnicity,health status,and social determinants associated with oral health status risk,health care providers can take an activ... Background:Having the ability to identify potential health risk factors such as lifestyle,ethnicity,health status,and social determinants associated with oral health status risk,health care providers can take an active role in health screening to discover any need for clinical preventive services,including dental preventive services,and can detect health problems.Methods:A descriptive type of cross-sectional study was conducted to explore the practice of common oral diseases among the patients visiting in the selected dental college and hospital in Bangladesh from October 2019 to December 2019.About 100 patients were interviewed through a semi-structured questionnaire,followed by an oral examination through a checklist and a face-to-face interview.A systematically random sampling technique was employed to select the study population.Results:Among them,the(21-30)year age group shows a maximum 20%,whereas the(71-80)year age group represents the minority with only 2%.Among them,56%were male and 44%were female.Students represent the majority of 26%,whereas others(day laborers)represent only 4%.Decayed teeth remained in 72%of cases,teeth were missing in 31%of cases,and filled teeth were present in 24%of cases.A majority of 71%clean teeth once daily,whereas only 29%clean teeth twice daily.Again,only 30%brush teeth at night and a maximum of 95%brush teeth in the morning.Moreover,a maximum of 68%use toothpaste and brushes,while only 4%use meswak for cleaning their teeth.About 4%of cases with no debris,51%of cases with less than 1/3rd of the tooth with debris,32%of cases with 1/3rd-2/3rd of the tooth with debris,and 13%of cases with more than 2/3rd of the tooth with debris were present.Again,about 30%had no calculus,52%less than 1/3rd of tooth,16%in between 1/3rd and 2/3rd of tooth,and 2%more than 2/3rd of the calculus was present.About 47%of mild,22%of moderate,6%of severe and 25%had no inflammation.Furthermore,for treatment purposes,20.69%was advised for scaling,19.66%for filling,16.90%for root canal treatment,17.59%for extraction,17.24%for prosthodontic treatment,1.03%for orthodontic treatment,2.07%for pulpotomy,2.41%for pulpectomy,and 2.41%for minor surgery.Overall,about 72%of the respondents,mostly the students,are suffering from decayed teeth,which may be due to a lack of frequency of brushing,indicating 95%that it is once daily.In addition,the most alarming situation among them is about 20.69%required scaling,which may be due to improper and inadequate brushing maintenance.Conclusion:to some extent,the above scenario may reflect the negative hallmark for our country’s younger generation in terms of oral health practice.Therefore,the establishment of a preventive oral health policy by our policymakers for the general population,mostly school-going students,on an emergency basis. 展开更多
关键词 dental caries ABSCESS broken down root broken down crown decayed missing filled tooth root canal treatment orthopentomogram intra oral periapical cone beam computed tomography body mass index
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山东省淄博市饮水型地方性氟中毒流行现状调查与分析
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作者 刘晓利 王丹 程忠哲 《中国当代医药》 CAS 2024年第6期116-119,共4页
目的采用横断面调查的方法,对山东省淄博市饮水型地方性氟中毒流行现状进行调查与分析。方法于2021年6月至12月对淄博市辖区内7个区县(张店区、临淄区、周村区、博山区、桓台县、高青县、沂源县)原有的氟中毒病区村及疑似病区村进行逐... 目的采用横断面调查的方法,对山东省淄博市饮水型地方性氟中毒流行现状进行调查与分析。方法于2021年6月至12月对淄博市辖区内7个区县(张店区、临淄区、周村区、博山区、桓台县、高青县、沂源县)原有的氟中毒病区村及疑似病区村进行逐一调查登记,对8~12岁1200名在校儿童进行氟斑牙患病率的调查分析,并对淄博市采取的114个改水降氟工程运行情况及运行后的水质状况进行监测与分析。结果地方性氟中毒在淄博市分布广泛,7个区县共3102个行政村中地方性氟中毒病区村459个,高氟危及人群达28万人。高青县是淄博市地方性氟中毒最为严重的地区,病区村占总数的75.2%;高青县中病区村数量占中病区村总数的92.2%,12个重病区均位于高青县。高青县也是8~12岁儿童氟斑牙的患病率最高的地区,20个村的88名儿童的氟斑牙检出率为100%,因受地理环境、气候及经济状况的影响,高青县345个病区村中仅有224个实施了改水降氟工程,占64.9%,是淄博市病区改水率最低的地区。结论淄博市地方性氟中毒总体处于低度流行趋势,但高青县地方性氟中毒防治形势仍然十分严峻,应加大防治经费的投入及改水降氟措施的落实力度,为早日控制地方性氟中毒的流行,保障人民群众免受地方性氟病的威胁做出努力。 展开更多
关键词 地方性氟中毒 氟斑牙 流行病学调查 淄博市 山东省
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异种胶原基质在种植体周角化黏膜增宽中的美学效果评价
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作者 杨艳 张佳 +3 位作者 马雪纯 蔡安东 周文娟 柳忠豪 《口腔疾病防治》 2024年第2期108-115,共8页
目的评价异种胶原基质在种植体周角化黏膜增宽中的稳定性及美学效果,为异种胶原基质材料的临床应用提供参考依据。方法获得医院伦理委员会审批及患者知情同意,收集2020年7月至2022年9月于滨州医学院附属烟台口腔医院因种植位点颊侧角化... 目的评价异种胶原基质在种植体周角化黏膜增宽中的稳定性及美学效果,为异种胶原基质材料的临床应用提供参考依据。方法获得医院伦理委员会审批及患者知情同意,收集2020年7月至2022年9月于滨州医学院附属烟台口腔医院因种植位点颊侧角化黏膜宽度(keratinized mucosa width,KMW)<2 mm行角化黏膜增宽的20例患者,共纳入36颗种植体,年龄(52.0±10.4)岁,其中女性18例,男性2例。根据移植材料的不同分为游离龈移植(free gingival graft,FGG)对照组和异种胶原基质试验组。测量术后1、3个月种植体颊侧KMW的增量效果及黏膜收缩率,评价术后黏膜瘢痕指数(mucosal scarring index,MSI)。结果术后3个月对照组的KMW为(3.67±1.06)mm,试验组的KMW为(2.96±0.98)mm,差异有统计学意义(t=2.076,P<0.05)。术后1个月试验组KMW收缩率为(33.34±16.30)%,对照组为(22.05±15.47)%,差异有统计学意义(P<0.05);术后3个月试验组KMW收缩率为(51.95±12.60)%,对照组为(37.44±16.30)%,差异有统计学意义(P<0.05)。术后3个月试验组在瘢痕5项指标中(瘢痕宽度、瘢痕凸度、瘢痕颜色、缝合痕迹、整体外观)均优于对照组,差异具有统计学意义(P<0.05)。结论异种胶原基质在种植体周角化黏膜增宽中可以增加KMW,同时获得更加自然协调的软组织美学效果,但具有较大的收缩率。 展开更多
关键词 牙种植 角化黏膜 角化黏膜宽度 种植体周角化黏膜增宽 游离龈移植术 异种胶原基质 角化黏膜收缩率 黏膜瘢痕指数 美学效果
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脑电双频指数监测下的浅镇静技术在20例牙科焦虑症患者下颌阻生齿拔除中的应用
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作者 于涛 辛志军 +2 位作者 尚将 孙静 曲伟栋 《口腔颌面外科杂志》 CAS 2024年第2期134-137,共4页
目的:探讨浅镇静技术在焦虑患者阻生牙拔除术中的应用。方法:对20例下颌阻生牙焦虑患者行丙泊酚静脉输入,在患者脑电双频指数(bispectral index,BIS)达到80~85时拔除阻生牙,术中监测患者心率(heart rate,HR)、平均动脉压(mean arterial ... 目的:探讨浅镇静技术在焦虑患者阻生牙拔除术中的应用。方法:对20例下颌阻生牙焦虑患者行丙泊酚静脉输入,在患者脑电双频指数(bispectral index,BIS)达到80~85时拔除阻生牙,术中监测患者心率(heart rate,HR)、平均动脉压(mean arterial pressure,MAP)、呼吸频率及血氧饱和度等,术后指导患者记录视觉模拟评分法(visual analogue scale,VAS)评分及询问患者顺行遗忘情况,采用SPSS 20.0软件包对数据进行数据统计,配对t检验比较术中生理指标与入室时的差异性,采用描述性分析法分析患者术中疼痛情况。结果:所有患者均顺利完成手术,未出现明显不良反应,术中HR、MAP、呼吸频率及血氧饱和度均未出现异常,患者术后VAS评分为1~3分,对手术开始、黏膜切开及牙钻声音顺行遗忘,即焦虑得到缓解。结论:针对牙科焦虑症患者下颌阻生牙的拔除,丙泊酚静脉浅镇静技术(BIS=80~85)即可达到较为满意的效果,减轻患者焦虑,提高舒适度。 展开更多
关键词 浅镇静 牙科焦虑症 下颌阻生牙 脑电双频指数
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固定正畸矫治80例病人唾液基质金属蛋白酶8和基质金属蛋白酶9的水平变化
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作者 张婉君 孔中楠 +3 位作者 马永平 崔敬雅 杨茜 马文盛 《安徽医药》 CAS 2024年第4期746-750,I0003,共6页
目的 探究固定正畸矫治病人唾液基质金属蛋白酶8(MMP-8)、基质金属蛋白酶9(MMP-9)水平的变化及临床意义。方法 选取2019年6月至2021年12月于保定市第二医院接受固定正畸矫治成年病人80例及健康受试者40例为研究对象。对病人固定矫治前(... 目的 探究固定正畸矫治病人唾液基质金属蛋白酶8(MMP-8)、基质金属蛋白酶9(MMP-9)水平的变化及临床意义。方法 选取2019年6月至2021年12月于保定市第二医院接受固定正畸矫治成年病人80例及健康受试者40例为研究对象。对病人固定矫治前(T1)、固定矫治1周(T2)、固定矫治1个月(T3)及健康受试者探诊出血(BOP)、菌斑指数(PLI)进行检测;收集健康受试者及病人T1、T2、T3时期唾液,采用ELISA检测唾液中MMP-8、MMP-9水平;流式细胞术对唾液白细胞含量进行检测;分别对MMP-8、MMP-9与牙龈BOP相关性进行分析;分离唾液白细胞,检测白细胞MMP-8、MMP-9表达水平变化。结果T2、T3时病人BOP[(21.36±8.79)%、(13.06±5.80)%]、PLI[(2.53±0.43)分、(1.89±0.39)分]及唾液中MMP-8[(0.43±0.11)μg/L、(0.32±0.10)μg/L]、MMP-9[(3.64±0.76)μg/L、(2.02±0.50)μg/L]、白细胞水平[(17 893.71±505.49)个、(8 532.18±421.89)个],显著高于T1水平[(5.05±2.11)%、(0.71±0.25)分、(0.16±0.08)μg/L、(0.25±0.13)μg/L、(2 308.66±178.04)个,P<0.05];唾液MMP-8、MMP-9水平与牙龈BOP、PLI呈正相关;进一步发现T2、T3时白细胞MMP-8、MMP-9表达水平显著高于T1水平(P<0.05)。受试者操作特征(ROC)曲线显示唾液MMP-8及MMP-9水平能较好预测牙龈炎程度。结论 正畸病人唾液MMP-8、MMP-9水平与牙龈炎病情呈正相关,唾液MMP-8、MMP-9可作为评估正畸病人牙龈炎的潜在生物标志物。 展开更多
关键词 牙龈炎 正畸矫正器 基质金属蛋白酶8 基质金属蛋白酶9 牙菌斑指数
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高氟干预成釉细胞钙稳态差异表达基因的筛选及分析
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作者 黄婷 刘霞 +5 位作者 王烛 陈霆 陈彬 白国辉 吴家媛 田源 《中国组织工程研究》 CAS 北大核心 2024年第16期2481-2487,共7页
背景:氟牙症是长期摄入大量氟所导致的牙釉质发育障碍,病因复杂,其发病机制有待深入研究。目的:通过转录组测序技术筛选高氟干预成釉细胞与钙稳态相关的差异表达基因,并进一步探索氟斑牙形成的分子机制。方法:分别用浓度为0,0.4,0.8,1.6... 背景:氟牙症是长期摄入大量氟所导致的牙釉质发育障碍,病因复杂,其发病机制有待深入研究。目的:通过转录组测序技术筛选高氟干预成釉细胞与钙稳态相关的差异表达基因,并进一步探索氟斑牙形成的分子机制。方法:分别用浓度为0,0.4,0.8,1.6,3.2,6.4 mmol/L的NaF处理成釉细胞LS824,48,72 h,检测细胞形态、细胞活性与细胞内钙离子浓度。分别用浓度为0,1.6,3.2 mmol/L的NaF处理成釉细胞LS824 h,通过转录组测序筛选差异表达基因,并对差异表达基因进行验证。结果与结论:①处理24 h后,NaF浓度0,0.4,0.8 mmol/L组细胞生长状态良好,细胞的数量增多,细胞轮廓清晰;当NaF浓度≥1.6 mmol/L,随着NaF浓度的增加,细胞体积逐渐皱缩变小、细胞数量减少。处理48,72 h后,NaF浓度0,0.4 mmol/L组细胞数量增加,0.8,1.6,3.2 mmol/L组细胞数量逐渐减少,细胞形态变圆、变小,6.4 mmol/L组细胞皱缩变圆悬浮于培养基中,几乎无细胞贴壁。当NaF浓度相同时,处理24 h后LS8细胞的生长状态最佳。CCK-8检测结果显示,当NaF浓度相同时,随着处理时间的延长,细胞活性减弱;当处理时间相同时,随着NaF浓度的增加,细胞活性减弱。处理24 h后,随着NaF浓度的增加,细胞内钙离子浓度增加。②转录组测序分析发现参与调控细胞钙稳态的基因:Hsp90b1、Canx、Calr、Hspa5的表达显著上调(P<0.05),Cacna1a的表达显著下调(P<0.05),该结果得到了RT-qPCR检测的验证。③结果显示,NaF对LS8细胞增殖的抑制作用可能与细胞内Ca2+浓度异常增加有关,其机制可能由蛋白质加工合成通路Hsp90b1、Canx、Calr、Hspa5表达上调和钙信号通路Cacna1a表达下调所导致。 展开更多
关键词 氟中毒 氟斑牙 成釉细胞 氟化钠 转录组测序 内质网应激 钙离子通道 钙离子探针
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3种咬合纸在人工种植牙修复中的应用效果比较
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作者 潘旭祯 王煜君 《中国口腔颌面外科杂志》 CAS 2024年第1期63-67,共5页
目的 :比较3种咬合纸在人工种植牙修复中的应用效果。方法 :选取2020年2月—2022年2月舟山市口腔医院117例人工种植牙修复患者,根据咬合紧密程度分为A、B、C 3组,每组39例,均为单颗患牙。A组采用12μm咬合纸,B组采用20μm咬合纸,C组采... 目的 :比较3种咬合纸在人工种植牙修复中的应用效果。方法 :选取2020年2月—2022年2月舟山市口腔医院117例人工种植牙修复患者,根据咬合紧密程度分为A、B、C 3组,每组39例,均为单颗患牙。A组采用12μm咬合纸,B组采用20μm咬合纸,C组采用30μm咬合纸。比较3组修复后3个月的牙周指标(种植体周骨吸收程度、种植体周围探诊深度、牙龈指数、牙松动度),修复前、修复当天、修复后3个月和修复后6个月咬合平衡指数绝对值,并评估患者及医师满意度。采用SPSS 22.0软件包对数据进行统计学分析。结果:3组牙周指标比较无统计学差异(P>0.05);3组组内咬合平衡指数绝对值比较,修复后6个月<修复后3个月<修复当天<修复前(P<0.05);修复后3个月,A组咬合平衡指数绝对值显著小于B组和C组(P<0.05);A组患者及医师满意度显著高于B组和C组(P<0.05)。结论:与20μm、30μm咬合纸比较,12μm咬合纸应用于人工种植牙修复能调整咬合平衡,提高患者及医师满意度。 展开更多
关键词 咬合纸 种植牙修复 种植体周骨吸收程度 咬合平衡指数
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Invisalign矫治器联合Damon Q自锁托槽对牙性错颌畸形的临床效果观察
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作者 马艳丽 王志航 庄金莉 《中国医疗美容》 2024年第2期78-81,共4页
目的探讨牙性错颌畸形患者采用Invisalign矫治器联合Damon Q自锁托槽治疗的临床效果。方法选择2021年6月至2023年6月我院收治的牙性错颌畸形患者96例,按照治疗方案不同将其分成两组,各48例。对照组采用Damon Q自锁托槽治疗,基于此,观察... 目的探讨牙性错颌畸形患者采用Invisalign矫治器联合Damon Q自锁托槽治疗的临床效果。方法选择2021年6月至2023年6月我院收治的牙性错颌畸形患者96例,按照治疗方案不同将其分成两组,各48例。对照组采用Damon Q自锁托槽治疗,基于此,观察组加用Invisalign矫治器。比较两组复诊间隔时间、牙周指数、锥形束计算机断层扫描(CBCT)检查结果及患者满意度。结果观察组复诊间隔时间为(16.23±2.04)周,对照组复诊间隔时间为(8.35±1.51)周,组间对比差异有统计学意义(P<0.05)。两组治疗前、后牙周指标、CBCT检查结果比较,差异无统计学意义(P>0.05)。两组治疗后牙周指标均高于同组治疗前,CBCT检查结果均低于治疗前,观察组满意度更高,差异有统计学意义(P<0.05)。结论相比单独采用Damon Q自锁托槽治疗,牙性错颌畸形患者加用Invisalign矫治器辅助治疗可获得理想的矫治效果,对患者牙周指数影响较小,利于改善CBCT检查指标,且可延长复诊间隔时间,提高患者满意度,应用价值更高。 展开更多
关键词 牙性错颌畸形 Invisalign矫治器 Damon Q自锁托槽 牙周指数
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正畸联合种植体支抗治疗牙前突畸形疗效及对PAR指数的影响
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作者 管丽丽 《智慧健康》 2024年第2期119-122,126,共5页
目的 探讨临床治疗牙前突畸形采取正畸、种植体支抗联合治疗的疗效及对PAR指数的影响。方法 选择2019年1月—2022年12月响水县中医院口腔科治疗牙前突畸形患者74例作为研究目标,按照治疗方案的不同分为对照组与观察组:观察组(37例)治疗... 目的 探讨临床治疗牙前突畸形采取正畸、种植体支抗联合治疗的疗效及对PAR指数的影响。方法 选择2019年1月—2022年12月响水县中医院口腔科治疗牙前突畸形患者74例作为研究目标,按照治疗方案的不同分为对照组与观察组:观察组(37例)治疗方案采取正畸种植体支抗联合方式;对照组(37例)治疗方案采取其他加强支抗正畸方式。对两组治疗效果予以观察比较。测量两组患者治疗后磨牙移位距离及上中切牙的凸距差、倾角差。对两组患者治疗前后PAR指数进行评估,对比结果数据组间差异。观察各组患者治疗后产生的不良反应,比较总发生率。结果 观察组牙前突畸形患者经种植支抗联合治疗后总有效率高于对照组(P<0.05)。同时经测量,观察组患者治疗后磨牙移位距离小于对照组,上中切牙的凸距差、倾角差大于对照组(P<0.05)。治疗前两组患者PAR指数评分结果比较差异无统计学意义(P>0.05),治疗后观察组患者PAR指数评分数值均低于对照组(P<0.05)。另外,治疗后观察组患者产生的不良反应总概率低于对照组(P<0.05)。结论 临床治疗牙前突畸形可在正畸的同时联合种植体支抗技术,可有效提高疗效,改善PAR指数评分,同时减少及减轻治疗后患者不良症状,提倡推广。 展开更多
关键词 正畸 种植体支抗 牙畸形 PAR指数
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牙周翻瓣术联合一次性根管填充治疗牙体牙髓病变患者的效果
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作者 李会浩 李小磊 高雅丽 《中国民康医学》 2024年第4期69-72,共4页
目的:观察牙周翻瓣术联合一次性根管填充治疗牙体牙髓病变患者的效果。方法:选取2020年2月至2023年1月该院收治的130例牙体牙髓病变患者进行前瞻性研究,按照随机数字表法分为研究组和对照组各65例。对照组采用一次性根管填充治疗,研究... 目的:观察牙周翻瓣术联合一次性根管填充治疗牙体牙髓病变患者的效果。方法:选取2020年2月至2023年1月该院收治的130例牙体牙髓病变患者进行前瞻性研究,按照随机数字表法分为研究组和对照组各65例。对照组采用一次性根管填充治疗,研究组在对照组基础上联合牙周翻瓣术治疗,比较两组临床疗效、炎性指标[C反应蛋白(CRP)、降钙素原(PCT)、白细胞计数(WBC)]水平、临床症状改善指标[咬合力、咀嚼效率、疼痛程度数字评估量表(NRS)]水平、牙周相关指标[龈沟出血指数(SBI)、牙齿松动度(TM)、牙龈指数(GI)、菌斑指数(PLI)]水平和不良事件发生率。结果:研究组治疗总有效率为92.31%(60/65),高于对照组的80.00%(52/65),差异有统计学意义(P<0.05);治疗后,两组PCT、CRP和WBC水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05);两组咀嚼效率和咬合力均高于治疗前,且研究组高于对照组,两组NRS评分均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05);两组SBI、TM、GI、PLI评分均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05);研究组不良事件发生率低于对照组,差异有统计学意义(P<0.05)。结论:牙周翻瓣术联合一次性根管填充治疗牙体牙髓病变患者可提高治疗总有效率,改善临床症状改善指标水平,降低牙周相关指标水平和不良事件发生率,其效果优于单纯一次性根管填充治疗。 展开更多
关键词 牙周翻瓣术 一次性根管填充 牙体牙髓病变 牙周指数 炎性 不良事件
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