Nonmechanical pumping of liquids is of key importance for applications from the biomedical microfluidic chip to drug delivery systems. In this paper, a new electrokinetic pump (EOP) system with polycarbonate nanoeha...Nonmechanical pumping of liquids is of key importance for applications from the biomedical microfluidic chip to drug delivery systems. In this paper, a new electrokinetic pump (EOP) system with polycarbonate nanoehannel membrane sandwiched between two membrane holders was constructed. The pump was tested with water and phosphate buffer at 1-6 V applied voltage, the maximum pressure and flow rate are 0.32 MPa (3.2 atm) and 4.2 μL/min for phosphate buffer, respectively. This proof-of-concept pump shows its potential use for drugs or chemical agents delivery by the usage of different membrane materials.展开更多
A micro fluidic system was developed and used for cell isolation on biochips. The flow speed could be precisely adjusted by a micropump, and the flow direction could be controlled by switching valves. The complete ope...A micro fluidic system was developed and used for cell isolation on biochips. The flow speed could be precisely adjusted by a micropump, and the flow direction could be controlled by switching valves. The complete operation was computer controlled. The control system for the micropump and microvalves is discussed here. This control system can be combined with other biochip devices to construct a micro total analysis system (μTAS).展开更多
文摘Nonmechanical pumping of liquids is of key importance for applications from the biomedical microfluidic chip to drug delivery systems. In this paper, a new electrokinetic pump (EOP) system with polycarbonate nanoehannel membrane sandwiched between two membrane holders was constructed. The pump was tested with water and phosphate buffer at 1-6 V applied voltage, the maximum pressure and flow rate are 0.32 MPa (3.2 atm) and 4.2 μL/min for phosphate buffer, respectively. This proof-of-concept pump shows its potential use for drugs or chemical agents delivery by the usage of different membrane materials.
基金the National Key Project (No.398890 0 1) the National Outstanding Young ScientistFund (No. 3982 5 10 8) from the National NaturalScience Foundation of Chinathe National"86 3"High Technology Program (No.10 3- 13- 0 5 - 0 2 )
文摘A micro fluidic system was developed and used for cell isolation on biochips. The flow speed could be precisely adjusted by a micropump, and the flow direction could be controlled by switching valves. The complete operation was computer controlled. The control system for the micropump and microvalves is discussed here. This control system can be combined with other biochip devices to construct a micro total analysis system (μTAS).