Background:The prevalence of pediatric mental illnesses has been increasing in recent years,with a great potential to impact on individual's functionality and adaptation in adulthood.Objective:This study aims to a...Background:The prevalence of pediatric mental illnesses has been increasing in recent years,with a great potential to impact on individual's functionality and adaptation in adulthood.Objective:This study aims to assess emotional and behavioral problems among schoolchildren in Herat City of Afghanistan.Methods:This cross-sectional study was conducted on schoolchildren(grade 5-10),between September and November 2021.Sociodemographic data was collected using a paper-based 14-item structured questionnaire.Data on emotional and behavioral problems was collected using the Strengths and Difficulties Questionnaire(SDQ)based on teachers'and children's report.Statistical analyses were performed in IBM SPSS Statistics(version 27).Results:A total of 418 students,including 190(45.5%)males and 228(54.5%)females with a mean age of 14.1±1.7(11-<18)years were included in the study.The prevalence of students*self-reported total difficulties and prosocial problem were 5.7%and 1.2%,respectively.An insignificant difference was observed between mean total difficulties scores between students'self-reported and teachers'reported SDQ.Gender,grade,concern about shortage of food,and concern about losing house were significantly predicting students'self-reported total difficulties scores.Conclusion:This is the first study to report the prevalence of emotional and behavioral problems among schoolchildren in Herat City,Afghanistan.This,together with relevant global literature,highlight the need to address pediatric mental health,and provide services aimed at preventing,and treating children with these problems around the world.展开更多
Objective:To determine the prevalence of infestation with head lice in primary schoolchildren in the eastern area of Bangkok,Thailand.Methods:The present study was to determine the head lice infestation(Pediculosis) l...Objective:To determine the prevalence of infestation with head lice in primary schoolchildren in the eastern area of Bangkok,Thailand.Methods:The present study was to determine the head lice infestation(Pediculosis) levels in primary schoolchildren,during May,2011 to July, 2011,A total of 3747 schoolchildren aged 5-12 years old from 12 selected primary school of Ladkrabang district,the eastern area of Bangkok were examined for head lice.Pediculosis was defined as the presence of at least on living adult,nymph and viable egg.Results:The overall head lice infestation rate was 23.32%and infestation rate was higher in girls(47.12%) than in boys(0%).The infestation rate among schoolchildren varied from 12.62%to 29.76%.The infestation rate among girls varied from 26.07%(12 years old group) to 55.89%(8 years old group).Conclusions: Pediculosis is a common public healtli problem affecting primary schoolchildren in eastern area of Bangkok and those levels are epidemic importance.展开更多
Objective:To evaluate the efficacy and side effects of praziquantel(PZQ) in the treatment of schistosomiasis in Ethiopia.Methods:In a cross-sectional study,stool specimens were collected from randomly selected 299 sch...Objective:To evaluate the efficacy and side effects of praziquantel(PZQ) in the treatment of schistosomiasis in Ethiopia.Methods:In a cross-sectional study,stool specimens were collected from randomly selected 299 school children in Shesha Kekele Elementary School,Wondo Genet, Southern Ethiopia,in April 2010.Stool specimens were examined using a single Kato-Katz thick smear for Schistosoma mansoni(5.mansoni) ova.Children who were found positive for S.mansoni were treated with a single oral dose of PZQ at 40 mg/kg bw and interviewed for treatment-related symptoms 24 hours after drug administration.Four weeks post-treatment,stool specimens were collected from the same children and examined following the same procedure as in the pretreatment.Drug efficacy was determined based on cure and egg reduction rates.Results:Pretreatment prevalence of S.mansoni infection was 74.9%with geometric mean egg count of 268. The evaluated generic PZQ produced an overall cure rate of 73.6%(P<0.000 1,OR:8.33,CI:5.3-13.1) and egg reduction rate of 68.2%(P=0.03,F=0.64).The cure rate showed significant association with age(x^2=H,P=0.004),the highest rate being observed in the 15-22 age group.83%of S. mansoni infected children showed various treatment-related symptoms,the most frerjiient being headache,nausea,and abdominal pain.These symptoms were associated with age(P<0.001) and pre-treatment intensity of infection(P<0.05).Conclusions:The present observations revealed relatively lower cure and egg reduction rates of the PZQ evaluated as compared to previous reports for other PZQ brands in Ethiopia.Hence,in depth studies are recommended to clarify whether the present relatively lower cure rate is the actual cure rate of the praziquantel evaluated,treatment failure,or reduced susceptibility of the parasite.Treatment-related side effects observed were transient and tolerable.展开更多
Objective:To investigate the prevalence of different intestinal parasitic infections among male primary schoolchildren in Al-Ahsa,Saudi Arabia,and to explore the possible relative socioeconomic, environmental and beha...Objective:To investigate the prevalence of different intestinal parasitic infections among male primary schoolchildren in Al-Ahsa,Saudi Arabia,and to explore the possible relative socioeconomic, environmental and behavioural sanitary correlates.Methods:A cross-sectional descriptive study was performed.A total of 1 289 male students aged from 7 to 12 years were selected randomly from 20 urban and 12 rural primary schools by multistage sampling method. Data collection was carried out by self administered questionnaire form to the parents/guardians of students and included inquires about socio-demographics,environmental conditions,and behavioural sanitary habits.Stool analysis was carried out to examine the presence of intestinal parasitic infections.Results:Overall prevalence of parasitic infections was 27.2%,more among rural students.Frequently encountered infections included Entamoeba histolytica/dispar(8.2%), Giardia lamblia(6.5%),Entamoeba coli(4.0%) and Enterobius vermicularis(1.6%).Logistic regression revealed that lower maternal educational level and occupational status,low family income,big family size,poor personal hygienic practices and positive history of previous intestinal infections among family members increased the likelihood of infections.Conclusions: Although of low magnitude,intestinal parasitic infections still represent a public health concern among male schoolchildren in Al-Ahsa region.Socio-demographic and poor personal hygienic habits are the main predictors for these infections.展开更多
Objective:To establish the prevalence and associated risk factors of Schistosoma mansoni(S.mansoni) infection among schoolchildren at a village in Wolaita Zone.Sothern Ethiopia,Methods:A cross-sectional study was carr...Objective:To establish the prevalence and associated risk factors of Schistosoma mansoni(S.mansoni) infection among schoolchildren at a village in Wolaita Zone.Sothern Ethiopia,Methods:A cross-sectional study was carried out among primary schoolchildren.A total of 384 randomly selected study subjects provided stool samples for parasitological examination by Kato-Katz and Formalin-Ether concentration techniques.Secondary parasitological data were obtained from Health Center Laboratory to see the previous history of.S.mansoni infection in the area.Statistical analysis was performed using SPSS software version 16.Results:From the total children examined.85.4% were found positive for at least one helminth infection.S.mansoni infection(81.3% ) was the most prevalent and the prevalence of STH was 32% ..Moderate and heavy infection intensities were only observed in S,mansoni infections.The overall heavy intensity of infection was 56.4% .Contact to Bisarc stream was the most important factor for S.mansoni infection(OR 3.9) followed by herding cattle near the stream(OR2.527).Males were twice more likely to get the infection than females(OR 1.923).Analysis of secondary parasitological data showed that S.mansoni infection was a leading helminthic infection over the past years.Conclusions:The present study found a higher intensity and prevalence of S.mansoni infection in a rural village of Wolaita Zone.Therefore,appropriate integrated control and prevention measures need to be implemented in the study area.展开更多
Objective:To obtain the prevalence with clinical symptoms of Cyclospora cayetanensis(C.cayetanensis),a coceidian protozoan parasite,in Thailand which is the cause of an intestinal infection characterized by sporadic-t...Objective:To obtain the prevalence with clinical symptoms of Cyclospora cayetanensis(C.cayetanensis),a coceidian protozoan parasite,in Thailand which is the cause of an intestinal infection characterized by sporadic-to-frequent explosive diarrhea.Methods:In a field surveyconducted by the Faculty of Tropical Medicine.Mahidol Lniversity.as part of the existing parasite-control program,a total of 2 540 faecal samples from villagers in Nan Province,Thailand,were collected and examined to determine the prevalence and clinical characteristics of parasitic infections.Results:Twelve cases of C.cayetanensis infection were found duritig faecal examination of schoolchildren aged 5-12 years.None exhibited obvious clinical symptoms,especially evidence of diarrhea:5 of 12 had loose faeces,one reported frequent symptoms of abdominal discomfort,and another had pale conjunctiva with low hematocrit.The children were generally asymptomatic.Conclusions:This finding confirms a public-health issue with potentially serious consequences whereby children can be exposed to an environment contaminated with food-und water-borne transmitted oocysts,anil can hence become infected with C.cayetunensis.展开更多
Introduction: Intestinal parasitism has been a challenge to overcome for the Mexican deworming campaign and this study determined the prevalence of these infections in schoolchildren treated with albendazole in Northw...Introduction: Intestinal parasitism has been a challenge to overcome for the Mexican deworming campaign and this study determined the prevalence of these infections in schoolchildren treated with albendazole in Northwestern Mexico. Methods: Study sites in marginal conditions, with gastrointestinal infections and albendazole intervention were selected. The Faust and Kato Katz techniques were used to identify the parasites spp. and the NCSS software was used for statistical analysis. Results: A total of 450, 389 and 364 schoolchildren participated in 2005, 2006, and 2007 respectively during this study. The mean age was 7.9 (±1.3). The estimated prevalences were of 42%, 30% and 37% for protozoa infections, and 11%, 12% and 11% for helminth infections in 2005, 2006 and 2007 respectively. Conclusion: The education strategies should be integrated into the Mexican deworming campaign.展开更多
The purpose of this study was to use the measurement of the PAEE taken from Actiheart in order to calculate the TEE in Costa Rican schoolchildren, and at the same time, to determine the effectiveness when it is compar...The purpose of this study was to use the measurement of the PAEE taken from Actiheart in order to calculate the TEE in Costa Rican schoolchildren, and at the same time, to determine the effectiveness when it is compared against the TEE obtained by the DLW. A total of sixteen male schoolchildren were measured for their total daily energy expenditure (TEE) with the doubly labeled water (DLW) technique. The TEE obtained by the Actiheart monitor was calculated and validated against the DWL. The TEE was obtained adding the physical activity energy expenditure given by the Actiheart, plus the basal metabolic rate, and the energy cost of growth. The Pearson’s product‐moment correlation coefficient and the paired t‐test sample were measured in order to identify the association of the data and to evidence the differences between both measurements of TEE respectively. The Lin’s concordance correlation coefficient and the Bland-Altman plot evaluated the concordance of both methods. The correlation between the TEE obtained by DLW and the one calculated by Actiheart was r = 0.97, P < 0.001. The paired t-test showed no significant differences between both methods. Lin’s concordance correlation coefficient was Cb = 0.99, classified as almost perfect. The study validated the TEE calculated with Actiheart against the TEE measured by the DLW.展开更多
The objective of this study was to assess the prevalence of iodine deficiency and possible correlated factors among schoolchildren in the municipality of Novo Cruzeiro-MG by means of an evaluation of urinary iodine ex...The objective of this study was to assess the prevalence of iodine deficiency and possible correlated factors among schoolchildren in the municipality of Novo Cruzeiro-MG by means of an evaluation of urinary iodine excretion. Five hundred and forty schoolchildren aged 6 to 14 years selected by stratified sampling, were evaluated. Urine samples were analyzed using the Sandell-Kolthoff method preconized by the WHO and iodine concentrations in the salt were assessed by means of volumetric analysis, in accordance with recommendations from the Ministry of Health. Iodine deficiency was observed in 38.9% of the schoolchildren. Of these, 28.7% of them presented slight deficiency, 6.2% of them were moderately deficient and 4% of them were seriously deficient. Median urinary iodine levels in the urban and rural population were 150.8 and 119.2 μg/L, respectively, with a clear distribution of iodine deficiency among the populations (p < 0.001) being registered. It was also observed that there was a high prevalence of deficient urinary iodine excretion among schoolchildren that consumed salt with an insufficient iodine content. In relation to the quality of the salt consumed by families, in 12.2% of the residences studied the iodine content in salt was below the recommended level (20 mg/kg), while the iodine content was below 15 mg/kg in only 5.3% of them. The results indicated that, although not characterized as a public health issue, according to WHO criteria, iodine deficiency showed very high prevalence among schoolchildren in this region. Regarding the iodine content of salt found in household consumption, our findings indicated the National Program of Salt Iodination was not efficient in the city, since it did not hit the target proposed by the Ministry of Health. Furthermore, low urinary iodine excretion associated with the consumption of salt with low iodine content suggests the need for periodical evaluations in order to provide effective control of the endemic disease.展开更多
Background: Cardiorespiratory fitness involves both cardiovascular and respiratory capacities. However, existing methods have been criticised for reflecting cardiovascular fitness, but not pulmonary fitness. The objec...Background: Cardiorespiratory fitness involves both cardiovascular and respiratory capacities. However, existing methods have been criticised for reflecting cardiovascular fitness, but not pulmonary fitness. The objective of this study was to investigate the relationship between these two testing parameters. Methods: A cross-sectional population-based physical fitness assessment was conducted in 23 schools. The body height and weight, lung capacity, and step test results of students aged 10-18 were recorded. Criterion-referenced standards from the China Sports Bureau were adopted, as they include separate measurements for cardiovascular and pulmonary fitness. Results: The Pearson coefficients of lung capacity and the step test index from 13,028 schoolchildren ranged from 0.007 to 0.086 and from 0.026 to 0.105 for boys and girls, respectively, showing that poor correlations exist between the two parameters. Cluster analysis resulted in three clusters of children with similar characteristics. A good degree of similarity was found between the two parameters in children obtaining an “excellent” grade, but only a moderate degree of similarity between the two parameters in those obtaining a “good”, “pass” or “fail” grade. Conclusion: When cardiovascular fitness and pulmonary fitness are considered separately, there is a poor correlation between them, thus indicating further studies of cardiopulmonary fitness measurements is necessary.展开更多
The aim of this study was to assess the prevalence of sleep-disordered breathing (SDB) symptoms among primary schoolchildren, and to objectively determine the influence of SDB on the intra-oral environment through the...The aim of this study was to assess the prevalence of sleep-disordered breathing (SDB) symptoms among primary schoolchildren, and to objectively determine the influence of SDB on the intra-oral environment through the analysis of saliva. A questionnaire survey was conducted among approximately 400 children from a primary school in Hiroshima. Parents were asked to complete the questionnaire and provide their contact information if they allowed the collection of saliva samples from their children. Thirty-eight chil- dren agreed to participate in the saliva study. Habit- ual snoring and cessation of breathing during sleep were found in approximately 8% and 1% of children, respectively. The present results showed significant correlations between snoring and mouth breathing. A significant association between excessive daytime sle- epiness (EDS) and learning problems was found. Fur- thermore, among children between the ages of 7 and 12 years, those with EDS and learning problems tended to be older. SDB symptom scores were statisti- cally significant only in relation to EDS. The present study also demonstrated significantly higher levels of salivary IgA and cortisol in children with sleep-re- lated disorders. The present study determined the pre- valence and characteristics of SDB among Japanese primary schoolchildren and their effects on the oral environment. Approximately 8% of primary school- children with habitual snoring might need to be care- fully monitored for SDB symptoms and immune sta- tus to ensure proper psychological and physical deve- lopment.展开更多
The aim of this study was to evaluate orthodontic treatment needs among Ferlo scholars. The design of the study was descriptive and transversal. For Inclusion criteria, children must live in Widou or live around Widou...The aim of this study was to evaluate orthodontic treatment needs among Ferlo scholars. The design of the study was descriptive and transversal. For Inclusion criteria, children must live in Widou or live around Widou’s school at least 6 km, be students at primary school of Widou Thiengoly, have a general health state which permits a clinical oral examination and teacher’s and/or parent’s agreement. The investigation was exhaustive and concerned the only school of the locality. More of 4/5 schoolchildren was 10.25 years ± 2.15 old. The majority (83.74%) of children presented an overjet between 0 and 3.5 mm, 1.63% presented a crossbite and 15.45% had OIM and RC different over to 2 mm. More of 30% of schoolchildren presented an overbite between 1 and 2 mm. More of 1/10 of them had an aesthetic teeth perception classified levels 8.9 and 10 corresponding to an orthodontic treatment needed according to IOTN while 20.33% had a score of 4 and 3.25% recorded score of 5 corresponding to a high treatment needed according to IOTN. The results of this study reveal that people need to be informed better about the therapeutic possibilities that orthodontics offer.展开更多
Introduction: Child obesity has important consequences on the child’s health and is related to the risk of developing chronic diseases. That brings up the need for research assessing the impact of obesity-and overwei...Introduction: Child obesity has important consequences on the child’s health and is related to the risk of developing chronic diseases. That brings up the need for research assessing the impact of obesity-and overweight-reduction programs with close attention to methodology aspects and precise indicators of the impact of such programs. Goal: Assessing the impact of a physical activity program on the plasma concentrations of adiponectin, leptin, and ghrelin in overweight and obese schoolchildren. Methods: Randomized controlled trial, double-blind, with 6-to 9-year-old overweight and obese school-children. A sample of 79 schoolchildren randomly distributed into control and intervention groups was subjected to a physical activity program. The levels of adiponectin, leptin, ghrelin, body mass index, body fat percentage, anthropometry, lipid profile and glycemia were evaluated. The program’s impact was assessed through multivariate linear regression models. Result: When comparing the groups, a significant difference was found for adiponectin, which shows an increase in the proportion of subjects with higher adiponectin concentrations for the intervention group and a reduction in body mass index and body fat percentage. Conclusion: The impact of the intervention program was positive in increasing adiponectin levels associated with a reduction in body mass index and body fat percentage.展开更多
There is much literature on the effects of fine particulate matter (PM2.5) on respiratory and cardiovascular health. However, few studies have evaluated the impact of PM2.5 on a population living in the vicinity of a ...There is much literature on the effects of fine particulate matter (PM2.5) on respiratory and cardiovascular health. However, few studies have evaluated the impact of PM2.5 on a population living in the vicinity of a massive deposit of mine tailings. A longitudinal panel study was performed to evaluate the association between exposure to PM2.5 and acute effects on lung function in schoolchildren from November 2012 to May 2013. Ambient levels of PM2.5 and its metal composition were measured. Lung function was evaluated using spirometric testing. Associations were quantified using GEE multilevel analysis controlling for confounders by using different lag time periods. The chemical characterization of PM2.5 had high levels of S > Na > Cl > Ca > Si > Fe > Al > Mg > K > Cu > Ti > and Zn, which would be associated with metals present in tailings. We found a negative association between the temporal variation of PM2.5 and changes in lung function specifically on forced vital capacity. Our results suggest that schoolchildren exposed to fine particulate matter from tailings deposited in the bay of Chanaral have their forced vital capacity decreased, which would affect their present and future lung development, increasing the risk of developing chronic respiratory diseases.展开更多
It＇s all about determination and persistence against the odds, befieves Zhang Ke. ＂You can realize your dreams as long as you persist,＂ says the 11-year-old. ＂You see, if the youngest brother had run away like his...It＇s all about determination and persistence against the odds, befieves Zhang Ke. ＂You can realize your dreams as long as you persist,＂ says the 11-year-old. ＂You see, if the youngest brother had run away like his elder brothers on that night, he would never have married the beautiful princess,＂ says the fifth-grader from Run＇an Public School in China＇s eastern Anhui Province.展开更多
Myopia is a huge health problem due to its high frequency,vision losses and public health cost.According to the World Health Organization,at least 2.2 billion people have vision impairment.Although myopia can be contr...Myopia is a huge health problem due to its high frequency,vision losses and public health cost.According to the World Health Organization,at least 2.2 billion people have vision impairment.Although myopia can be controlled at its early and middle stages,unfortunately,no cure can be achieved so far.Among the methods to control myopia,atropine,a muscarinic receptor antagonist,is the oldest but still the most effective for retardation of myopia progression.Despite such a fact,standard protocols have not been established for clinicians to use atropine for treatment of myopia.In this article,a concise and up to date summary of myopia epidemiology and pathogenesis and summarized therapeutic effects and side effects,possible mechanisms and application methods of atropine were provided in hope for clinical doctors to effectively control this problematic disease.At present,the protocol is recommend:use higher dose(1%)of atropine intermittently to effectively slowdown myopia progression in schoolchildren for 2y,and to significantly reduce side effects of atropine by decrease of atropine frequency for 1y and inhibit myopic rebound by withdrawal of topical atropine gradually for 1y.Application of a lower dose(0.05%)atropine regime should also be considered due to its effectiveness and application at regular basis.展开更多
目的探讨全民加碘10年后浙江省8-10岁儿童的甲状腺容积的正常值及其校正方法,建立浙江省8-10岁儿童甲状腺容积的正常值标准。方法以2005年全国第5次碘缺乏病监测中的浙江省1110名8-10岁儿童B超测得的甲状腺容积数据为基础,应用SPSS10.0 ...目的探讨全民加碘10年后浙江省8-10岁儿童的甲状腺容积的正常值及其校正方法,建立浙江省8-10岁儿童甲状腺容积的正常值标准。方法以2005年全国第5次碘缺乏病监测中的浙江省1110名8-10岁儿童B超测得的甲状腺容积数据为基础,应用SPSS10.0 for windows统计软件进行统计分析检验。结果儿童甲状腺容积随着年龄的增加而递增,性别对甲状腺容积没有影响。浙江省8-10岁儿童甲状腺容积的正常值标准按年龄分组分别为：4.7、5.3和6.0ml。体质指数校正法（BMIV）、体重身高甲状腺容积指数法（WHVI）、体表面积甲状腺容积指数法（BSAV）和身高甲状腺容积指数法（HVI）四种甲状腺容积校正方法中,HVI校正法比其它校正方法更方便实用。结论浙江省8-10岁儿童甲状腺容积各年龄段的正常值标准较为合理,可为今后浙江省碘缺乏病监测及我国修订儿童甲状腺容积正常值标准提供依据。HVI是目前校正甲状腺容积的最适合方法。展开更多
基金supported by the International Assistance Mission,Herat Office(Grant number#IDR0220526IAM).
文摘Background:The prevalence of pediatric mental illnesses has been increasing in recent years,with a great potential to impact on individual's functionality and adaptation in adulthood.Objective:This study aims to assess emotional and behavioral problems among schoolchildren in Herat City of Afghanistan.Methods:This cross-sectional study was conducted on schoolchildren(grade 5-10),between September and November 2021.Sociodemographic data was collected using a paper-based 14-item structured questionnaire.Data on emotional and behavioral problems was collected using the Strengths and Difficulties Questionnaire(SDQ)based on teachers'and children's report.Statistical analyses were performed in IBM SPSS Statistics(version 27).Results:A total of 418 students,including 190(45.5%)males and 228(54.5%)females with a mean age of 14.1±1.7(11-<18)years were included in the study.The prevalence of students*self-reported total difficulties and prosocial problem were 5.7%and 1.2%,respectively.An insignificant difference was observed between mean total difficulties scores between students'self-reported and teachers'reported SDQ.Gender,grade,concern about shortage of food,and concern about losing house were significantly predicting students'self-reported total difficulties scores.Conclusion:This is the first study to report the prevalence of emotional and behavioral problems among schoolchildren in Herat City,Afghanistan.This,together with relevant global literature,highlight the need to address pediatric mental health,and provide services aimed at preventing,and treating children with these problems around the world.
文摘Objective:To determine the prevalence of infestation with head lice in primary schoolchildren in the eastern area of Bangkok,Thailand.Methods:The present study was to determine the head lice infestation(Pediculosis) levels in primary schoolchildren,during May,2011 to July, 2011,A total of 3747 schoolchildren aged 5-12 years old from 12 selected primary school of Ladkrabang district,the eastern area of Bangkok were examined for head lice.Pediculosis was defined as the presence of at least on living adult,nymph and viable egg.Results:The overall head lice infestation rate was 23.32%and infestation rate was higher in girls(47.12%) than in boys(0%).The infestation rate among schoolchildren varied from 12.62%to 29.76%.The infestation rate among girls varied from 26.07%(12 years old group) to 55.89%(8 years old group).Conclusions: Pediculosis is a common public healtli problem affecting primary schoolchildren in eastern area of Bangkok and those levels are epidemic importance.
基金financially supported by the Vice President Officefor Research and Dean of School of Graduate Studies and Aklilu Lemma Institute of Pathobiology(grant No.RDP/PY-014/09)
文摘Objective:To evaluate the efficacy and side effects of praziquantel(PZQ) in the treatment of schistosomiasis in Ethiopia.Methods:In a cross-sectional study,stool specimens were collected from randomly selected 299 school children in Shesha Kekele Elementary School,Wondo Genet, Southern Ethiopia,in April 2010.Stool specimens were examined using a single Kato-Katz thick smear for Schistosoma mansoni(5.mansoni) ova.Children who were found positive for S.mansoni were treated with a single oral dose of PZQ at 40 mg/kg bw and interviewed for treatment-related symptoms 24 hours after drug administration.Four weeks post-treatment,stool specimens were collected from the same children and examined following the same procedure as in the pretreatment.Drug efficacy was determined based on cure and egg reduction rates.Results:Pretreatment prevalence of S.mansoni infection was 74.9%with geometric mean egg count of 268. The evaluated generic PZQ produced an overall cure rate of 73.6%(P<0.000 1,OR:8.33,CI:5.3-13.1) and egg reduction rate of 68.2%(P=0.03,F=0.64).The cure rate showed significant association with age(x^2=H,P=0.004),the highest rate being observed in the 15-22 age group.83%of S. mansoni infected children showed various treatment-related symptoms,the most frerjiient being headache,nausea,and abdominal pain.These symptoms were associated with age(P<0.001) and pre-treatment intensity of infection(P<0.05).Conclusions:The present observations revealed relatively lower cure and egg reduction rates of the PZQ evaluated as compared to previous reports for other PZQ brands in Ethiopia.Hence,in depth studies are recommended to clarify whether the present relatively lower cure rate is the actual cure rate of the praziquantel evaluated,treatment failure,or reduced susceptibility of the parasite.Treatment-related side effects observed were transient and tolerable.
基金supported by a grant from the Deanship of Scientific Research,King Faisal University
文摘Objective:To investigate the prevalence of different intestinal parasitic infections among male primary schoolchildren in Al-Ahsa,Saudi Arabia,and to explore the possible relative socioeconomic, environmental and behavioural sanitary correlates.Methods:A cross-sectional descriptive study was performed.A total of 1 289 male students aged from 7 to 12 years were selected randomly from 20 urban and 12 rural primary schools by multistage sampling method. Data collection was carried out by self administered questionnaire form to the parents/guardians of students and included inquires about socio-demographics,environmental conditions,and behavioural sanitary habits.Stool analysis was carried out to examine the presence of intestinal parasitic infections.Results:Overall prevalence of parasitic infections was 27.2%,more among rural students.Frequently encountered infections included Entamoeba histolytica/dispar(8.2%), Giardia lamblia(6.5%),Entamoeba coli(4.0%) and Enterobius vermicularis(1.6%).Logistic regression revealed that lower maternal educational level and occupational status,low family income,big family size,poor personal hygienic practices and positive history of previous intestinal infections among family members increased the likelihood of infections.Conclusions: Although of low magnitude,intestinal parasitic infections still represent a public health concern among male schoolchildren in Al-Ahsa region.Socio-demographic and poor personal hygienic habits are the main predictors for these infections.
文摘Objective:To establish the prevalence and associated risk factors of Schistosoma mansoni(S.mansoni) infection among schoolchildren at a village in Wolaita Zone.Sothern Ethiopia,Methods:A cross-sectional study was carried out among primary schoolchildren.A total of 384 randomly selected study subjects provided stool samples for parasitological examination by Kato-Katz and Formalin-Ether concentration techniques.Secondary parasitological data were obtained from Health Center Laboratory to see the previous history of.S.mansoni infection in the area.Statistical analysis was performed using SPSS software version 16.Results:From the total children examined.85.4% were found positive for at least one helminth infection.S.mansoni infection(81.3% ) was the most prevalent and the prevalence of STH was 32% ..Moderate and heavy infection intensities were only observed in S,mansoni infections.The overall heavy intensity of infection was 56.4% .Contact to Bisarc stream was the most important factor for S.mansoni infection(OR 3.9) followed by herding cattle near the stream(OR2.527).Males were twice more likely to get the infection than females(OR 1.923).Analysis of secondary parasitological data showed that S.mansoni infection was a leading helminthic infection over the past years.Conclusions:The present study found a higher intensity and prevalence of S.mansoni infection in a rural village of Wolaita Zone.Therefore,appropriate integrated control and prevention measures need to be implemented in the study area.
基金partially supported by a grant from the Faculty of Tropical Medicine,Mahidol University
文摘Objective:To obtain the prevalence with clinical symptoms of Cyclospora cayetanensis(C.cayetanensis),a coceidian protozoan parasite,in Thailand which is the cause of an intestinal infection characterized by sporadic-to-frequent explosive diarrhea.Methods:In a field surveyconducted by the Faculty of Tropical Medicine.Mahidol Lniversity.as part of the existing parasite-control program,a total of 2 540 faecal samples from villagers in Nan Province,Thailand,were collected and examined to determine the prevalence and clinical characteristics of parasitic infections.Results:Twelve cases of C.cayetanensis infection were found duritig faecal examination of schoolchildren aged 5-12 years.None exhibited obvious clinical symptoms,especially evidence of diarrhea:5 of 12 had loose faeces,one reported frequent symptoms of abdominal discomfort,and another had pale conjunctiva with low hematocrit.The children were generally asymptomatic.Conclusions:This finding confirms a public-health issue with potentially serious consequences whereby children can be exposed to an environment contaminated with food-und water-borne transmitted oocysts,anil can hence become infected with C.cayetunensis.
文摘Introduction: Intestinal parasitism has been a challenge to overcome for the Mexican deworming campaign and this study determined the prevalence of these infections in schoolchildren treated with albendazole in Northwestern Mexico. Methods: Study sites in marginal conditions, with gastrointestinal infections and albendazole intervention were selected. The Faust and Kato Katz techniques were used to identify the parasites spp. and the NCSS software was used for statistical analysis. Results: A total of 450, 389 and 364 schoolchildren participated in 2005, 2006, and 2007 respectively during this study. The mean age was 7.9 (±1.3). The estimated prevalences were of 42%, 30% and 37% for protozoa infections, and 11%, 12% and 11% for helminth infections in 2005, 2006 and 2007 respectively. Conclusion: The education strategies should be integrated into the Mexican deworming campaign.
文摘The purpose of this study was to use the measurement of the PAEE taken from Actiheart in order to calculate the TEE in Costa Rican schoolchildren, and at the same time, to determine the effectiveness when it is compared against the TEE obtained by the DLW. A total of sixteen male schoolchildren were measured for their total daily energy expenditure (TEE) with the doubly labeled water (DLW) technique. The TEE obtained by the Actiheart monitor was calculated and validated against the DWL. The TEE was obtained adding the physical activity energy expenditure given by the Actiheart, plus the basal metabolic rate, and the energy cost of growth. The Pearson’s product‐moment correlation coefficient and the paired t‐test sample were measured in order to identify the association of the data and to evidence the differences between both measurements of TEE respectively. The Lin’s concordance correlation coefficient and the Bland-Altman plot evaluated the concordance of both methods. The correlation between the TEE obtained by DLW and the one calculated by Actiheart was r = 0.97, P < 0.001. The paired t-test showed no significant differences between both methods. Lin’s concordance correlation coefficient was Cb = 0.99, classified as almost perfect. The study validated the TEE calculated with Actiheart against the TEE measured by the DLW.
文摘The objective of this study was to assess the prevalence of iodine deficiency and possible correlated factors among schoolchildren in the municipality of Novo Cruzeiro-MG by means of an evaluation of urinary iodine excretion. Five hundred and forty schoolchildren aged 6 to 14 years selected by stratified sampling, were evaluated. Urine samples were analyzed using the Sandell-Kolthoff method preconized by the WHO and iodine concentrations in the salt were assessed by means of volumetric analysis, in accordance with recommendations from the Ministry of Health. Iodine deficiency was observed in 38.9% of the schoolchildren. Of these, 28.7% of them presented slight deficiency, 6.2% of them were moderately deficient and 4% of them were seriously deficient. Median urinary iodine levels in the urban and rural population were 150.8 and 119.2 μg/L, respectively, with a clear distribution of iodine deficiency among the populations (p < 0.001) being registered. It was also observed that there was a high prevalence of deficient urinary iodine excretion among schoolchildren that consumed salt with an insufficient iodine content. In relation to the quality of the salt consumed by families, in 12.2% of the residences studied the iodine content in salt was below the recommended level (20 mg/kg), while the iodine content was below 15 mg/kg in only 5.3% of them. The results indicated that, although not characterized as a public health issue, according to WHO criteria, iodine deficiency showed very high prevalence among schoolchildren in this region. Regarding the iodine content of salt found in household consumption, our findings indicated the National Program of Salt Iodination was not efficient in the city, since it did not hit the target proposed by the Ministry of Health. Furthermore, low urinary iodine excretion associated with the consumption of salt with low iodine content suggests the need for periodical evaluations in order to provide effective control of the endemic disease.
文摘Background: Cardiorespiratory fitness involves both cardiovascular and respiratory capacities. However, existing methods have been criticised for reflecting cardiovascular fitness, but not pulmonary fitness. The objective of this study was to investigate the relationship between these two testing parameters. Methods: A cross-sectional population-based physical fitness assessment was conducted in 23 schools. The body height and weight, lung capacity, and step test results of students aged 10-18 were recorded. Criterion-referenced standards from the China Sports Bureau were adopted, as they include separate measurements for cardiovascular and pulmonary fitness. Results: The Pearson coefficients of lung capacity and the step test index from 13,028 schoolchildren ranged from 0.007 to 0.086 and from 0.026 to 0.105 for boys and girls, respectively, showing that poor correlations exist between the two parameters. Cluster analysis resulted in three clusters of children with similar characteristics. A good degree of similarity was found between the two parameters in children obtaining an “excellent” grade, but only a moderate degree of similarity between the two parameters in those obtaining a “good”, “pass” or “fail” grade. Conclusion: When cardiovascular fitness and pulmonary fitness are considered separately, there is a poor correlation between them, thus indicating further studies of cardiopulmonary fitness measurements is necessary.
文摘The aim of this study was to assess the prevalence of sleep-disordered breathing (SDB) symptoms among primary schoolchildren, and to objectively determine the influence of SDB on the intra-oral environment through the analysis of saliva. A questionnaire survey was conducted among approximately 400 children from a primary school in Hiroshima. Parents were asked to complete the questionnaire and provide their contact information if they allowed the collection of saliva samples from their children. Thirty-eight chil- dren agreed to participate in the saliva study. Habit- ual snoring and cessation of breathing during sleep were found in approximately 8% and 1% of children, respectively. The present results showed significant correlations between snoring and mouth breathing. A significant association between excessive daytime sle- epiness (EDS) and learning problems was found. Fur- thermore, among children between the ages of 7 and 12 years, those with EDS and learning problems tended to be older. SDB symptom scores were statisti- cally significant only in relation to EDS. The present study also demonstrated significantly higher levels of salivary IgA and cortisol in children with sleep-re- lated disorders. The present study determined the pre- valence and characteristics of SDB among Japanese primary schoolchildren and their effects on the oral environment. Approximately 8% of primary school- children with habitual snoring might need to be care- fully monitored for SDB symptoms and immune sta- tus to ensure proper psychological and physical deve- lopment.
文摘The aim of this study was to evaluate orthodontic treatment needs among Ferlo scholars. The design of the study was descriptive and transversal. For Inclusion criteria, children must live in Widou or live around Widou’s school at least 6 km, be students at primary school of Widou Thiengoly, have a general health state which permits a clinical oral examination and teacher’s and/or parent’s agreement. The investigation was exhaustive and concerned the only school of the locality. More of 4/5 schoolchildren was 10.25 years ± 2.15 old. The majority (83.74%) of children presented an overjet between 0 and 3.5 mm, 1.63% presented a crossbite and 15.45% had OIM and RC different over to 2 mm. More of 30% of schoolchildren presented an overbite between 1 and 2 mm. More of 1/10 of them had an aesthetic teeth perception classified levels 8.9 and 10 corresponding to an orthodontic treatment needed according to IOTN while 20.33% had a score of 4 and 3.25% recorded score of 5 corresponding to a high treatment needed according to IOTN. The results of this study reveal that people need to be informed better about the therapeutic possibilities that orthodontics offer.
文摘Introduction: Child obesity has important consequences on the child’s health and is related to the risk of developing chronic diseases. That brings up the need for research assessing the impact of obesity-and overweight-reduction programs with close attention to methodology aspects and precise indicators of the impact of such programs. Goal: Assessing the impact of a physical activity program on the plasma concentrations of adiponectin, leptin, and ghrelin in overweight and obese schoolchildren. Methods: Randomized controlled trial, double-blind, with 6-to 9-year-old overweight and obese school-children. A sample of 79 schoolchildren randomly distributed into control and intervention groups was subjected to a physical activity program. The levels of adiponectin, leptin, ghrelin, body mass index, body fat percentage, anthropometry, lipid profile and glycemia were evaluated. The program’s impact was assessed through multivariate linear regression models. Result: When comparing the groups, a significant difference was found for adiponectin, which shows an increase in the proportion of subjects with higher adiponectin concentrations for the intervention group and a reduction in body mass index and body fat percentage. Conclusion: The impact of the intervention program was positive in increasing adiponectin levels associated with a reduction in body mass index and body fat percentage.
基金the Chilean National Fund for Research and Development in Health(FONIS N°SA11|2244).
文摘There is much literature on the effects of fine particulate matter (PM2.5) on respiratory and cardiovascular health. However, few studies have evaluated the impact of PM2.5 on a population living in the vicinity of a massive deposit of mine tailings. A longitudinal panel study was performed to evaluate the association between exposure to PM2.5 and acute effects on lung function in schoolchildren from November 2012 to May 2013. Ambient levels of PM2.5 and its metal composition were measured. Lung function was evaluated using spirometric testing. Associations were quantified using GEE multilevel analysis controlling for confounders by using different lag time periods. The chemical characterization of PM2.5 had high levels of S > Na > Cl > Ca > Si > Fe > Al > Mg > K > Cu > Ti > and Zn, which would be associated with metals present in tailings. We found a negative association between the temporal variation of PM2.5 and changes in lung function specifically on forced vital capacity. Our results suggest that schoolchildren exposed to fine particulate matter from tailings deposited in the bay of Chanaral have their forced vital capacity decreased, which would affect their present and future lung development, increasing the risk of developing chronic respiratory diseases.
文摘It＇s all about determination and persistence against the odds, befieves Zhang Ke. ＂You can realize your dreams as long as you persist,＂ says the 11-year-old. ＂You see, if the youngest brother had run away like his elder brothers on that night, he would never have married the beautiful princess,＂ says the fifth-grader from Run＇an Public School in China＇s eastern Anhui Province.
基金Supported by the Basic Research Fund for Science and Technology Department of Yunnan Province and Kunming Medical University(No.202401AY070001-289).
文摘Myopia is a huge health problem due to its high frequency,vision losses and public health cost.According to the World Health Organization,at least 2.2 billion people have vision impairment.Although myopia can be controlled at its early and middle stages,unfortunately,no cure can be achieved so far.Among the methods to control myopia,atropine,a muscarinic receptor antagonist,is the oldest but still the most effective for retardation of myopia progression.Despite such a fact,standard protocols have not been established for clinicians to use atropine for treatment of myopia.In this article,a concise and up to date summary of myopia epidemiology and pathogenesis and summarized therapeutic effects and side effects,possible mechanisms and application methods of atropine were provided in hope for clinical doctors to effectively control this problematic disease.At present,the protocol is recommend:use higher dose(1%)of atropine intermittently to effectively slowdown myopia progression in schoolchildren for 2y,and to significantly reduce side effects of atropine by decrease of atropine frequency for 1y and inhibit myopic rebound by withdrawal of topical atropine gradually for 1y.Application of a lower dose(0.05%)atropine regime should also be considered due to its effectiveness and application at regular basis.
文摘目的探讨全民加碘10年后浙江省8-10岁儿童的甲状腺容积的正常值及其校正方法,建立浙江省8-10岁儿童甲状腺容积的正常值标准。方法以2005年全国第5次碘缺乏病监测中的浙江省1110名8-10岁儿童B超测得的甲状腺容积数据为基础,应用SPSS10.0 for windows统计软件进行统计分析检验。结果儿童甲状腺容积随着年龄的增加而递增,性别对甲状腺容积没有影响。浙江省8-10岁儿童甲状腺容积的正常值标准按年龄分组分别为：4.7、5.3和6.0ml。体质指数校正法（BMIV）、体重身高甲状腺容积指数法（WHVI）、体表面积甲状腺容积指数法（BSAV）和身高甲状腺容积指数法（HVI）四种甲状腺容积校正方法中,HVI校正法比其它校正方法更方便实用。结论浙江省8-10岁儿童甲状腺容积各年龄段的正常值标准较为合理,可为今后浙江省碘缺乏病监测及我国修订儿童甲状腺容积正常值标准提供依据。HVI是目前校正甲状腺容积的最适合方法。
