An efficient green protocol for the preparation 3,4,6-trisubstituted 2-pyridone of employing a condensation reaction of cyanoacetamide and acetylacetone in the presence of KAl（SO4）2·12H2O in water has been desc...An efficient green protocol for the preparation 3,4,6-trisubstituted 2-pyridone of employing a condensation reaction of cyanoacetamide and acetylacetone in the presence of KAl（SO4）2·12H2O in water has been described. The present procedure offers advantage such as shorter reaction time, simple workup, and excellent yields.展开更多
基金Iran National Science Foundation for partial support of this work
文摘An efficient green protocol for the preparation 3,4,6-trisubstituted 2-pyridone of employing a condensation reaction of cyanoacetamide and acetylacetone in the presence of KAl（SO4）2·12H2O in water has been described. The present procedure offers advantage such as shorter reaction time, simple workup, and excellent yields.
